Gene info for Dshi_1119 in Dinoroseobacter shibae DFL-12

Updated annotation (from data): DNA damage response helicase, ligase-associated
Rationale: Conserved and specific phenotype: important for resisting cisplatin. Related to Lhr, which is either a DNA:DNA or DNA:RNA helicase, but lacks the long C-terminal extension that might have a regulatory role (see putative winged helix domain in E. coli lhr). This is also related to the archael protein saci_1500, which has also been linked to DNA damage response, as a mutant is sensitive to UV (PMID: 26148716)
Original annotation: DEAD/H associated domain protein (RefSeq)
Type 1: Protein-coding gene
Located on scaffold 57145, - strand, nucleotides 1,143,663 to 1,146,086
See nucleotide sequence around Dshi_1119 or for all of scaffold 57145

Other databases: MicrobesOnline, NCBI, IMG: 2501022984, uniprot: A8LHR4

Nearby Genes

500 ntDshi_1114 and Dshi_1115 are separated by 81 nucleotidesDshi_1115 and Dshi_1116 are separated by 139 nucleotidesDshi_1116 and Dshi_1117 are separated by 81 nucleotidesDshi_1117 and Dshi_1118 overlap by 4 nucleotidesDshi_1118 and Dshi_1119 are separated by 23 nucleotidesDshi_1119 and Dshi_1120 are separated by 48 nucleotidesDshi_1120 and Dshi_1121 are separated by 36 nucleotidesDshi_1121 and Dshi_1122 are separated by 7 nucleotidesDshi_1122 and Dshi_1123 are separated by 47 nucleotidesDshi_1123 and Dshi_1124 are separated by 52 nucleotides Dshi_1114: Dshi_1114 - tRNA(Ile)-lysidine synthetase (RefSeq), at 1,138,429 to 1,139,682 _1114 Dshi_1115: Dshi_1115 - ATP-dependent metalloprotease FtsH (RefSeq), at 1,139,764 to 1,141,680 _1115 Dshi_1116: Dshi_1116 - hypothetical protein (RefSeq), at 1,141,820 to 1,142,431 _1116 Dshi_1117: Dshi_1117 - thioesterase superfamily protein (RefSeq), at 1,142,513 to 1,142,929 _1117 Dshi_1118: Dshi_1118 - hypothetical protein (RefSeq), at 1,142,926 to 1,143,639 _1118 Dshi_1119: Dshi_1119 - DNA damage response helicase, ligase-associated (from data), at 1,143,663 to 1,146,086 _1119 Dshi_1120: Dshi_1120 - hypothetical protein (RefSeq), at 1,146,135 to 1,147,442 _1120 Dshi_1121: Dshi_1121 - peptidase A24A prepilin type IV (RefSeq), at 1,147,479 to 1,147,988 _1121 Dshi_1122: Dshi_1122 - tetratricopeptide region (RefSeq), at 1,147,996 to 1,148,847 _1122 Dshi_1123: Dshi_1123 - Tetratricopeptide TPR_2 repeat protein (RefSeq), at 1,148,895 to 1,149,425 _1123 Dshi_1124: Dshi_1124 - type II secretion system protein (RefSeq), at 1,149,478 to 1,150,473 _1124
Locus Name Description Strand Phenotype
Dshi_1114 Dshi_1114 tRNA(Ile)-lysidine synthetase (RefSeq) + no data
Dshi_1115 Dshi_1115 ATP-dependent metalloprotease FtsH (RefSeq) + no data
Dshi_1116 Dshi_1116 hypothetical protein (RefSeq) + strong
Dshi_1117 Dshi_1117 thioesterase superfamily protein (RefSeq) - insig.
Dshi_1118 Dshi_1118 hypothetical protein (RefSeq) - no data
Dshi_1119 Dshi_1119 DNA damage response helicase, ligase-associated (from data) - strong
Dshi_1120 Dshi_1120 hypothetical protein (RefSeq) - insig.
Dshi_1121 Dshi_1121 peptidase A24A prepilin type IV (RefSeq) - insig.
Dshi_1122 Dshi_1122 tetratricopeptide region (RefSeq) - cofit
Dshi_1123 Dshi_1123 Tetratricopeptide TPR_2 repeat protein (RefSeq) - cofit
Dshi_1124 Dshi_1124 type II secretion system protein (RefSeq) - insig.

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