Gene info for BT3759 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): N-succinylglutamylphosphate reductase (EC 1.2.1.-)
Rationale: Important for fitness in most defined media, except when arginine is provided. Hits TIGR01850, which is described as N-acetyl-gamma-glutamyl-phosphate reductase, but Bacteroidetes use succinylated intermediates for arginine synthesis (see PMC7311316).
Original annotation: N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, - strand, nucleotides 4,879,609 to 4,880,577
See nucleotide sequence around BT3759 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS18955, uniprot: Q8A1A7

Nearby Genes

500 ntBT3754 and BT3755 are separated by 114 nucleotidesBT3755 and BT3756 are separated by 7 nucleotidesBT3756 and BT3757 are separated by 39 nucleotidesBT3757 and BT3758 are separated by 135 nucleotidesBT3758 and BT3759 are separated by 13 nucleotidesBT3759 and BT3760 overlap by 4 nucleotidesBT3760 and BT3761 are separated by 13 nucleotidesBT3761 and BT3762 are separated by 25 nucleotidesBT3762 and BT3763 are separated by 233 nucleotidesBT3763 and BT3764 are separated by 59 nucleotides BT3754: BT3754 - conserved hypothetical protein (NCBI ptt file), at 4,874,003 to 4,875,193 BT3754 BT3755: BT3755 - acetyl-coenzyme A synthetase (NCBI ptt file), at 4,875,308 to 4,876,963 BT3755 BT3756: BT3756 - transcriptional regulator (NCBI ptt file), at 4,876,971 to 4,877,525 BT3756 BT3757: BT3757 - pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data), at 4,877,565 to 4,878,338 BT3757 BT3758: BT3758 - N-succinylornithine aminotransferase (EC 2.6.1.81) (from data), at 4,878,474 to 4,879,595 BT3758 BT3759: BT3759 - N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data), at 4,879,609 to 4,880,577 BT3759 BT3760: BT3760 - arginosuccinate synthetase (EC 6.3.4.5) (from data), at 4,880,574 to 4,881,782 BT3760 BT3761: BT3761 - N-succinylglutamate synthase (from data), at 4,881,796 to 4,882,374 BT3761 BT3762: BT3762 - arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file), at 4,882,400 to 4,882,873 BT3762 BT3763: BT3763 - rhamnulose kinase/L-fuculose kinase (NCBI ptt file), at 4,883,107 to 4,884,564 BT3763 BT3764: BT3764 - L-rhamnose isomerase (NCBI ptt file), at 4,884,624 to 4,885,880 BT3764
Locus Name Description Strand Phenotype
BT3754 BT3754 conserved hypothetical protein (NCBI ptt file) + insig.
BT3755 BT3755 acetyl-coenzyme A synthetase (NCBI ptt file) - sig.
BT3756 BT3756 transcriptional regulator (NCBI ptt file) - sig.
BT3757 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) - strong
BT3758 BT3758 N-succinylornithine aminotransferase (EC 2.6.1.81) (from data) - strong
BT3759 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) - strong
BT3760 BT3760 arginosuccinate synthetase (EC 6.3.4.5) (from data) - strong
BT3761 BT3761 N-succinylglutamate synthase (from data) - strong
BT3762 BT3762 arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file) - strong
BT3763 BT3763 rhamnulose kinase/L-fuculose kinase (NCBI ptt file) + strong
BT3764 BT3764 L-rhamnose isomerase (NCBI ptt file) + strong

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