Gene info for BT3758 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): N-succinylornithine aminotransferase (EC 2.6.1.81)
Rationale: Important for fitness in most defined media, except when arginine is provided. Similar to acetylornithine aminotransferases (such as argD from B. subtilis), but Bacteroidetes use succinylated intermediates for arginine synthesis (see PMC7311316).
Original annotation: acetylornithine aminotransferase (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, - strand, nucleotides 4,878,474 to 4,879,595
See nucleotide sequence around BT3758 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS18950, uniprot: Q8A1A8

Nearby Genes

500 ntBT3753 and BT3754 are separated by 30 nucleotidesBT3754 and BT3755 are separated by 114 nucleotidesBT3755 and BT3756 are separated by 7 nucleotidesBT3756 and BT3757 are separated by 39 nucleotidesBT3757 and BT3758 are separated by 135 nucleotidesBT3758 and BT3759 are separated by 13 nucleotidesBT3759 and BT3760 overlap by 4 nucleotidesBT3760 and BT3761 are separated by 13 nucleotidesBT3761 and BT3762 are separated by 25 nucleotidesBT3762 and BT3763 are separated by 233 nucleotides BT3753: BT3753 - endo-beta-N-acetylglucosaminidase F2 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F2) (NCBI ptt file), at 4,872,869 to 4,873,972 BT3753 BT3754: BT3754 - conserved hypothetical protein (NCBI ptt file), at 4,874,003 to 4,875,193 BT3754 BT3755: BT3755 - acetyl-coenzyme A synthetase (NCBI ptt file), at 4,875,308 to 4,876,963 BT3755 BT3756: BT3756 - transcriptional regulator (NCBI ptt file), at 4,876,971 to 4,877,525 BT3756 BT3757: BT3757 - pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data), at 4,877,565 to 4,878,338 BT3757 BT3758: BT3758 - N-succinylornithine aminotransferase (EC 2.6.1.81) (from data), at 4,878,474 to 4,879,595 BT3758 BT3759: BT3759 - N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data), at 4,879,609 to 4,880,577 BT3759 BT3760: BT3760 - arginosuccinate synthetase (EC 6.3.4.5) (from data), at 4,880,574 to 4,881,782 BT3760 BT3761: BT3761 - N-succinylglutamate synthase (from data), at 4,881,796 to 4,882,374 BT3761 BT3762: BT3762 - arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file), at 4,882,400 to 4,882,873 BT3762 BT3763: BT3763 - rhamnulose kinase/L-fuculose kinase (NCBI ptt file), at 4,883,107 to 4,884,564 BT3763
Locus Name Description Strand Phenotype
BT3753 BT3753 endo-beta-N-acetylglucosaminidase F2 precursor (mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F2) (NCBI ptt file) + insig.
BT3754 BT3754 conserved hypothetical protein (NCBI ptt file) + insig.
BT3755 BT3755 acetyl-coenzyme A synthetase (NCBI ptt file) - sig.
BT3756 BT3756 transcriptional regulator (NCBI ptt file) - sig.
BT3757 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) - strong
BT3758 BT3758 N-succinylornithine aminotransferase (EC 2.6.1.81) (from data) - strong
BT3759 BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) - strong
BT3760 BT3760 arginosuccinate synthetase (EC 6.3.4.5) (from data) - strong
BT3761 BT3761 N-succinylglutamate synthase (from data) - strong
BT3762 BT3762 arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file) - strong
BT3763 BT3763 rhamnulose kinase/L-fuculose kinase (NCBI ptt file) + strong

Or browse nearby genes

Or see the comparative fitness browser