Gene info for BT3395 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): N-succinylglutamate kinase (EC 2.7.2.-)
Rationale: Important for fitness in most defined media, except when arginine is provided. Bacteroidetes use succinylated intermediates, and a close homolog from B. fragilis prefers N-succinylglutamate as a substrate (see PMC7311316 and references therein), so this is N-succinylglutamate kinase, not N-acetylglutamate kinase.
Original annotation: putative acetylglutamate kinase (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, + strand, nucleotides 4,375,854 to 4,376,627
See nucleotide sequence around BT3395 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS17185, uniprot: Q8A2B0

Nearby Genes

500 ntBT3390 and BT3391 are separated by 12 nucleotidesBT3391 and BT3392 are separated by 138 nucleotidesBT3392 and BT3393 are separated by 60 nucleotidesBT3393 and BT3394 are separated by 117 nucleotidesBT3394 and BT3395 are separated by 59 nucleotidesBT3395 and BT3396 are separated by 61 nucleotidesBT3396 and BT3397 overlap by 11 nucleotidesBT3397 and BT3398 are separated by 175 nucleotidesBT3398 and BT3399 are separated by 135 nucleotidesBT3399 and BT3400 are separated by 39 nucleotides BT3390: BT3390 - conserved hypothetical protein (NCBI ptt file), at 4,371,376 to 4,371,807 BT3390 BT3391: BT3391 - ribonuclease H-related protein (NCBI ptt file), at 4,371,820 to 4,372,455 BT3391 BT3392: BT3392 - nitroreductase (NCBI ptt file), at 4,372,594 to 4,373,196 BT3392 BT3393: BT3393 - shikimate kinase (NCBI ptt file), at 4,373,257 to 4,373,784 BT3393 BT3394: BT3394 - putative arginine decarboxylase (NCBI ptt file), at 4,373,902 to 4,375,794 BT3394 BT3395: BT3395 - N-succinylglutamate kinase (EC 2.7.2.-) (from data), at 4,375,854 to 4,376,627 BT3395 BT3396: BT3396 - RNA polymerase ECF-type sigma factor (NCBI ptt file), at 4,376,689 to 4,377,198 BT3396 BT3397: BT3397 - hypothetical protein (NCBI ptt file), at 4,377,188 to 4,377,664 BT3397 BT3398: BT3398 - conserved hypothetical protein (NCBI ptt file), at 4,377,840 to 4,378,625 BT3398 BT3399: BT3399 - putative zinc protease (NCBI ptt file), at 4,378,761 to 4,379,459 BT3399 BT3400: BT3400 - hypothetical protein (NCBI ptt file), at 4,379,499 to 4,379,894 BT3400
Locus Name Description Strand Phenotype
BT3390 BT3390 conserved hypothetical protein (NCBI ptt file) + no data
BT3391 BT3391 ribonuclease H-related protein (NCBI ptt file) - no data
BT3392 BT3392 nitroreductase (NCBI ptt file) + insig.
BT3393 BT3393 shikimate kinase (NCBI ptt file) + no data
BT3394 BT3394 putative arginine decarboxylase (NCBI ptt file) + strong
BT3395 BT3395 N-succinylglutamate kinase (EC 2.7.2.-) (from data) + strong
BT3396 BT3396 RNA polymerase ECF-type sigma factor (NCBI ptt file) + strong
BT3397 BT3397 hypothetical protein (NCBI ptt file) + sig.
BT3398 BT3398 conserved hypothetical protein (NCBI ptt file) - sig.
BT3399 BT3399 putative zinc protease (NCBI ptt file) + insig.
BT3400 BT3400 hypothetical protein (NCBI ptt file) - sig.

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