Gene info for BT3328 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): hyaluronic acid endo-lyase (PL29)
Rationale: Specifically important in carbon source Hyaluronic acid sodium salt from Streptococcus equi. In vitro, it also degrades other glycosaminoglycans such as chondroitin sulfate and dermatan sulfate (PMCID:PMC6240882), but it is not important for utilizing chondroitin sulfate. We do not have fitness data for dermatan sulfate.
Original annotation: hypothetical protein (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, - strand, nucleotides 4,277,069 to 4,279,675
See nucleotide sequence around BT3328 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS16850, uniprot: Q8A2H7

Nearby Genes

500 ntBT3323 and BT3324 are separated by 231 nucleotidesBT3324 and BT3325 are separated by 794 nucleotidesBT3325 and BT3326 are separated by 86 nucleotidesBT3326 and BT3327 are separated by 27 nucleotidesBT3327 and BT3328 are separated by 180 nucleotidesBT3328 and BT3329 are separated by 13 nucleotidesBT3329 and BT3330 are separated by 38 nucleotidesBT3330 and BT3331 are separated by 33 nucleotidesBT3331 and BT3332 are separated by 40 nucleotidesBT3332 and BT3333 are separated by 159 nucleotides BT3323: BT3323 - hypothetical protein (NCBI ptt file), at 4,268,551 to 4,269,072 BT3323 BT3324: BT3324 - chondroitinase (chondroitin lyase) precursor (NCBI ptt file), at 4,269,304 to 4,272,348 BT3324 BT3325: BT3325 - hypothetical protein (NCBI ptt file), at 4,273,143 to 4,274,372 BT3325 BT3326: BT3326 - putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain (NCBI ptt file), at 4,274,459 to 4,275,403 BT3326 BT3327: BT3327 - ATP-dependent DNA helicase recG (NCBI ptt file), at 4,275,431 to 4,276,888 BT3327 BT3328: BT3328 - hyaluronic acid endo-lyase (PL29) (from data), at 4,277,069 to 4,279,675 BT3328 BT3329: BT3329 - hypothetical protein (NCBI ptt file), at 4,279,689 to 4,281,626 BT3329 BT3330: BT3330 - hypothetical protein (NCBI ptt file), at 4,281,665 to 4,282,708 BT3330 BT3331: BT3331 - Outer membrane binding protein for chondroitin sulfate and hyaluronic acid (susD-like) (from data), at 4,282,742 to 4,284,460 BT3331 BT3332: BT3332 - TonB-dependent receptor for chondroitin sulfate and hyaluronic acid (susC-like) (from data), at 4,284,501 to 4,287,662 BT3332 BT3333: BT3333 - arylsulfatase A precursor (ASA) (NCBI ptt file), at 4,287,822 to 4,289,357 BT3333
Locus Name Description Strand Phenotype
BT3323 BT3323 hypothetical protein (NCBI ptt file) + insig.
BT3324 BT3324 chondroitinase (chondroitin lyase) precursor (NCBI ptt file) + insig.
BT3325 BT3325 hypothetical protein (NCBI ptt file) - strong
BT3326 BT3326 putative nifR3 family TIM-barrel enzyme with dihydrouridine synthase domain (NCBI ptt file) - sig.
BT3327 BT3327 ATP-dependent DNA helicase recG (NCBI ptt file) - insig.
BT3328 BT3328 hyaluronic acid endo-lyase (PL29) (from data) - sig.
BT3329 BT3329 hypothetical protein (NCBI ptt file) - sig.
BT3330 BT3330 hypothetical protein (NCBI ptt file) - strong
BT3331 BT3331 Outer membrane binding protein for chondroitin sulfate and hyaluronic acid (susD-like) (from data) - strong
BT3332 BT3332 TonB-dependent receptor for chondroitin sulfate and hyaluronic acid (susC-like) (from data) - strong
BT3333 BT3333 arylsulfatase A precursor (ASA) (NCBI ptt file) - sig.

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