Gene info for BT1861 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): 2-isopropylmalate synthase (EC 2.3.3.13)
Rationale: Important for fitness in most defined media. Hits TIGR00973 and 47% identical to the 2-isopropylmalate synthase from Leptospira interrogans (Q8F445).
Original annotation: 2-isopropylmalate synthase (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, - strand, nucleotides 2,334,703 to 2,336,199
See nucleotide sequence around BT1861 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS09425, uniprot: Q8A6L6

Nearby Genes

500 ntBT1856 and BT1857 are separated by 202 nucleotidesBT1857 and BT1858 are separated by 90 nucleotidesBT1858 and BT1859 are separated by 5 nucleotidesBT1859 and BT1860 are separated by 42 nucleotidesBT1860 and BT1861 are separated by 77 nucleotidesBT1861 and BT1862 are separated by 397 nucleotidesBT1862 and BT_r04 are separated by 175 nucleotidesBT_r04 and BT_r05 are separated by 418 nucleotidesBT_r05 and tRNA-Ala are separated by 174 nucleotidestRNA-Ala and tRNA-Ile are separated by 54 nucleotides BT1856: BT1856 - hypothetical protein (NCBI ptt file), at 2,328,407 to 2,329,726 BT1856 BT1857: BT1857 - 3-isopropylmalate dehydrogenase (NCBI ptt file), at 2,329,929 to 2,330,990 BT1857 BT1858: BT1858 - (R)-citramalate synthase (EC 2.3.1.182) (from data), at 2,331,081 to 2,332,580 BT1858 BT1859: BT1859 - 3-isopropylmalate dehydratase small subunit (NCBI ptt file), at 2,332,586 to 2,333,188 BT1859 BT1860: BT1860 - 3-isopropylmalate dehydratase large subunit (NCBI ptt file), at 2,333,231 to 2,334,625 BT1860 BT1861: BT1861 - 2-isopropylmalate synthase (EC 2.3.3.13) (from data), at 2,334,703 to 2,336,199 BT1861 BT1862: BT1862 - hypothetical protein (NCBI ptt file), at 2,336,597 to 2,336,839 BT1862 BT_r04: BT_r04 - 5S ribosomal RNA (RefSeq), at 2,337,015 to 2,337,048 _r04 BT_r05: BT_r05 - 23S ribosomal RNA (RefSeq), at 2,337,467 to 2,340,119 _r05 BT_t31: tRNA-Ala - tRNA-Ala (RefSeq), at 2,340,294 to 2,340,367 tRNA-Ala BT_t32: tRNA-Ile - tRNA-Ile (RefSeq), at 2,340,422 to 2,340,495 tRNA-Ile
Locus Name Description Strand Phenotype
BT1856 BT1856 hypothetical protein (NCBI ptt file) - insig.
BT1857 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) - strong
BT1858 BT1858 (R)-citramalate synthase (EC 2.3.1.182) (from data) - strong
BT1859 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) - strong
BT1860 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) - strong
BT1861 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) - strong
BT1862 BT1862 hypothetical protein (NCBI ptt file) - insig.
BT_r04 BT_r04 5S ribosomal RNA (RefSeq) - no data
BT_r05 BT_r05 23S ribosomal RNA (RefSeq) - no data
BT_t31 tRNA-Ala tRNA-Ala (RefSeq) - no data
BT_t32 tRNA-Ile tRNA-Ile (RefSeq) - no data

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