Gene info for BT0588 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): BexA: efflux pump for ciprofloxacin, lomefloxacin, and paraquat
Rationale: Specifically important in stress Paraquat dichloride; stress Lomefloxacin hydrochloride; and potentially important during growth in ciprofloxacin, which is reported to be a substrate of this efflux pump (PMCID:PMC90835), along with norfloxacin and ethidium bromide.
Original annotation: BexA, multidrug efflux pump (NCBI ptt file)
Type 1: Protein-coding gene
Located on scaffold 241, - strand, nucleotides 726,297 to 727,628
See nucleotide sequence around BT0588 or for all of scaffold 241

Other databases: MicrobesOnline, NCBI, refseq: BT_RS02885, uniprot: Q8AA77

Nearby Genes

500 ntBT0583 and BT0584 are separated by 153 nucleotidesBT0584 and BT0585 are separated by 19 nucleotidesBT0585 and BT0586 are separated by 116 nucleotidesBT0586 and BT0587 are separated by 145 nucleotidesBT0587 and BT0588 are separated by 47 nucleotidesBT0588 and BT0589 are separated by 85 nucleotidesBT0589 and BT0590 are separated by 62 nucleotidesBT0590 and BT0591 are separated by 184 nucleotidesBT0591 and BT0592 are separated by 95 nucleotidesBT0592 and BT0593 are separated by 26 nucleotides BT0583: BT0583 - hypothetical protein (NCBI ptt file), at 720,420 to 721,514 BT0583 BT0584: BT0584 - putative outer membrane protein (NCBI ptt file), at 721,668 to 722,666 BT0584 BT0585: BT0585 - conserved hypothetical protein (NCBI ptt file), at 722,686 to 723,195 BT0585 BT0586: BT0586 - hypothetical protein (NCBI ptt file), at 723,312 to 724,004 BT0586 BT0587: BT0587 - prolyl oligopeptidase family protein (NCBI ptt file), at 724,150 to 726,249 BT0587 BT0588: BT0588 - BexA: efflux pump for ciprofloxacin, lomefloxacin, and paraquat (from data), at 726,297 to 727,628 BT0588 BT0589: BT0589 - conserved hypothetical protein (NCBI ptt file), at 727,714 to 729,570 BT0589 BT0590: BT0590 - CTP synthase (UTP-ammonia ligase) (NCBI ptt file), at 729,633 to 731,246 BT0590 BT0591: BT0591 - hypothetical protein (NCBI ptt file), at 731,431 to 732,882 BT0591 BT0592: BT0592 - conserved hypothetical protein (NCBI ptt file), at 732,978 to 733,763 BT0592 BT0593: BT0593 - conserved hypothetical protein (NCBI ptt file), at 733,790 to 734,155 BT0593
Locus Name Description Strand Phenotype
BT0583 BT0583 hypothetical protein (NCBI ptt file) + insig.
BT0584 BT0584 putative outer membrane protein (NCBI ptt file) + sig.
BT0585 BT0585 conserved hypothetical protein (NCBI ptt file) + sig.
BT0586 BT0586 hypothetical protein (NCBI ptt file) + insig.
BT0587 BT0587 prolyl oligopeptidase family protein (NCBI ptt file) - sig.
BT0588 BT0588 BexA: efflux pump for ciprofloxacin, lomefloxacin, and paraquat (from data) - strong
BT0589 BT0589 conserved hypothetical protein (NCBI ptt file) - no data
BT0590 BT0590 CTP synthase (UTP-ammonia ligase) (NCBI ptt file) - no data
BT0591 BT0591 hypothetical protein (NCBI ptt file) + strong
BT0592 BT0592 conserved hypothetical protein (NCBI ptt file) - insig.
BT0593 BT0593 conserved hypothetical protein (NCBI ptt file) - insig.

Or browse nearby genes

Or see the comparative fitness browser