Experiment setAIT094 for Pseudomonas fluorescens FW300-N2E2

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Urea nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3783 -6.5 -4.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_64 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4353 -6.0 -5.8 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_4597 -5.9 -8.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3610 -5.9 -5.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3253 -5.8 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_77 -5.8 -4.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4596 -5.7 -7.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5006 -5.6 -7.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3630 -5.5 -6.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2258 -5.5 -9.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4825 -5.5 -8.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_1187 -5.5 -7.4 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3751 -5.4 -11.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5150 -5.3 -3.7 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3842 -5.3 -5.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_71 -5.3 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3248 -5.3 -6.2 Probable transmembrane protein compare
Pf6N2E2_1186 -5.2 -5.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3060 -5.1 -4.4 Outer membrane protein H precursor compare
Pf6N2E2_4279 -5.0 -12.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_5177 -5.0 -11.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3826 -4.8 -5.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5175 -4.8 -12.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3782 -4.8 -3.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3940 -4.7 -10.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3752 -4.7 -20.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4826 -4.6 -8.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5176 -4.6 -9.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_66 -4.6 -10.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4047 -4.6 -6.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2073 -4.6 -5.4 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4048 -4.5 -8.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2574 -4.5 -3.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_4564 -4.4 -12.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3839 -4.4 -5.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3841 -4.3 -6.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3553 -4.1 -7.2 Urease (EC 3.5.1.5) (from data) conserved
Pf6N2E2_4278 -4.0 -12.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3252 -4.0 -9.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_658 -4.0 -13.1 sensor histidine kinase compare
Pf6N2E2_3932 -4.0 -5.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_1672 -4.0 -12.0 hypothetical protein compare
Pf6N2E2_4372 -3.9 -6.0 FIG00460773: hypothetical protein compare
Pf6N2E2_3072 -3.8 -12.4 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_2261 -3.8 -3.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_2885 -3.7 -7.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3552 -3.7 -10.4 Urease accessory protein UreD conserved
Pf6N2E2_3258 -3.7 -3.6 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4759 -3.5 -16.0 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4764 -3.5 -7.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_50 -3.4 -9.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5780 -3.4 -11.2 Periplasmic protease compare
Pf6N2E2_4277 -3.4 -9.7 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4987 -3.3 -2.1 MaoC-like domain protein compare
Pf6N2E2_1188 -3.3 -7.1 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_3251 -3.2 -12.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3571 -3.2 -5.5 Urease accessory protein UreF compare
Pf6N2E2_4187 -3.1 -4.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3257 -3.1 -4.2 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4803 -3.1 -2.9 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5156 -3.0 -2.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3556 -3.0 -10.6 Urease (EC 3.5.1.5) (from data) compare
Pf6N2E2_4761 -3.0 -9.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5014 -2.9 -1.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3984 -2.9 -12.2 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3573 -2.9 -6.1 HupE-UreJ family metal transporter compare
Pf6N2E2_1056 -2.9 -1.7 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3170 -2.8 -7.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3554 -2.8 -8.5 GCN5-related N-acetyltransferase compare
Pf6N2E2_3260 -2.7 -5.4 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2218 -2.7 -5.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3572 -2.7 -9.7 Urease accessory protein UreG conserved
Pf6N2E2_4762 -2.6 -4.6 Biotin synthesis protein BioH compare
Pf6N2E2_4416 -2.6 -3.5 Tyrosine recombinase XerC compare
Pf6N2E2_4638 -2.6 -2.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3938 -2.5 -10.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3825 -2.5 -4.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4763 -2.5 -9.8 Biotin synthesis protein BioC compare
Pf6N2E2_3570 -2.5 -4.8 Urease accessory protein UreE conserved
Pf6N2E2_2863 -2.5 -7.8 Gluconate permease compare
Pf6N2E2_3264 -2.5 -3.2 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_63 -2.5 -3.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5536 -2.5 -1.7 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5579 -2.3 -5.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3349 -2.3 -3.7 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2074 -2.3 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5527 -2.3 -3.3 Cold shock protein CspC compare
Pf6N2E2_3461 -2.3 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1190 -2.3 -5.5 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_2588 -2.2 -3.8 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4611 -2.2 -3.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_1189 -2.2 -4.9 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_4276 -2.2 -6.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2217 -2.1 -5.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4631 -2.1 -9.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_5190 -2.1 -9.9 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_302 -2.0 -3.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2465 -2.0 -6.0 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5103 -2.0 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_3198 -1.9 -2.8 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4009 -1.9 -10.1 GGDEF domain protein compare
Pf6N2E2_5950 -1.9 -3.2 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4476 -1.9 -6.4 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_5666 -1.9 -9.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2274 -1.8 -4.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3460 -1.8 -2.0 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_5494 -1.8 -5.8 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_2864 -1.8 -2.7 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4071 -1.7 -4.5 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3074 -1.7 -2.1 FIG00960973: hypothetical protein compare
Pf6N2E2_3351 -1.7 -4.9 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_51 -1.7 -6.2 hypothetical protein compare
Pf6N2E2_2474 -1.7 -7.9 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_5508 -1.7 -2.7 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_2375 -1.7 -3.7 Response regulator NasT compare
Pf6N2E2_4453 -1.7 -11.8 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3770 -1.6 -2.0 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3666 -1.6 -3.6 InaA protein compare
Pf6N2E2_2507 -1.6 -6.4 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2746 -1.6 -5.9 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_2186 -1.6 -5.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_178 -1.6 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5667 -1.5 -6.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2253 -1.5 -2.6 hypothetical protein compare
Pf6N2E2_2065 -1.5 -4.1 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2899 -1.5 -5.2 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3338 -1.4 -2.3 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_5676 -1.4 -2.6 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5237 -1.4 -2.5 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_146 -1.4 -1.5 Transcriptional regulator, MarR family compare
Pf6N2E2_4659 -1.4 -3.4 Lipoprotein, putative compare
Pf6N2E2_2897 -1.4 -7.2 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_3835 -1.4 -2.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3077 -1.4 -3.7 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_5155 -1.3 -2.1 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5242 -1.3 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_3908 -1.3 -5.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4181 -1.3 -1.4 Organic hydroperoxide resistance protein compare
Pf6N2E2_2986 -1.3 -3.7 Transcriptional regulator, LuxR family compare
Pf6N2E2_2506 -1.3 -8.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5524 -1.3 -7.9 Outer membrane porin, OprD family compare
Pf6N2E2_5919 -1.3 -1.7 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_4658 -1.2 -3.5 FIG00955006: hypothetical protein compare
Pf6N2E2_5219 -1.2 -4.8 FIG140336: TPR domain protein compare
Pf6N2E2_1191 -1.2 -5.1 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_5746 -1.2 -2.6 Cobalamin synthase compare
Pf6N2E2_3612 -1.2 -2.0 HflK protein compare
Pf6N2E2_5339 -1.2 -4.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3869 -1.2 -7.6 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3282 -1.2 -1.9 FIG005080: Possible exported protein compare
Pf6N2E2_4969 -1.2 -1.2 hypothetical protein compare
Pf6N2E2_3607 -1.1 -5.0 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_4364 -1.1 -2.3 Protein YicC compare
Pf6N2E2_2264 -1.1 -3.3 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1246 -1.1 -2.3 FIG00961372: hypothetical protein compare
Pf6N2E2_1147 -1.1 -2.5 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_2012 -1.1 -2.4 hypothetical protein compare
Pf6N2E2_3611 -1.1 -1.1 HflC protein compare
Pf6N2E2_4162 -1.1 -2.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_6065 -1.1 -1.7 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_2061 -1.1 -3.8 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
Pf6N2E2_4418 -1.1 -1.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_5257 -1.1 -6.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2068 -1.1 -5.4 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3941 -1.1 -2.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_1099 -1.1 -2.1 Hypothetical protein GlcG in glycolate utilization operon compare
Pf6N2E2_4824 -1.0 -2.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_4369 -1.0 -2.2 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_2088 -1.0 -1.5 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_2473 -1.0 -1.1 Major outer membrane lipoprotein I compare
Pf6N2E2_1694 -1.0 -1.4 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_6164 -1.0 -1.1 tRNA-Val-TAC compare
Pf6N2E2_3535 -1.0 -4.7 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_4352 -1.0 -2.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4661 -1.0 -2.6 KluA regulatory protein compare
Pf6N2E2_3687 -1.0 -2.2 FIG00959437: hypothetical protein compare
Pf6N2E2_3658 -1.0 -3.9 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4075 -1.0 -3.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_5258 -1.0 -5.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_1391 -1.0 -2.8 DNA-binding response regulator, LuxR family compare
Pf6N2E2_2425 -1.0 -2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5728 -1.0 -2.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3134 -1.0 -1.0 hypothetical protein compare
Pf6N2E2_1673 -0.9 -2.1 Transcriptional regulator, TetR family compare
Pf6N2E2_1545 -0.9 -2.9 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_5816 -0.9 -1.4 Smr domain protein compare
Pf6N2E2_1396 -0.9 -1.2 ABC transporter, ATP-binding protein compare
Pf6N2E2_2117 -0.9 -6.5 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_3027 -0.9 -1.3 Baseplate assembly protein V compare
Pf6N2E2_1081 -0.9 -1.6 probable membrane protein YPO3302 compare
Pf6N2E2_5740 -0.9 -3.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_5520 -0.9 -4.1 Sensory box histidine kinase compare
Pf6N2E2_1886 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_2753 -0.9 -1.9 HtrA protease/chaperone protein compare
Pf6N2E2_2855 -0.9 -3.0 DGPFAETKE compare
Pf6N2E2_613 -0.9 -1.4 lipoprotein, putative compare
Pf6N2E2_3521 -0.9 -5.2 Sensor histidine kinase/response regulator compare
Pf6N2E2_37 -0.9 -2.3 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4534 -0.9 -3.3 hypothetical protein compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source Urea in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Urea across organisms