Experiment setAIT090 for Pseudomonas fluorescens FW300-N2E2

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Cytosine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.7 -4.6 Probable transmembrane protein compare
Pf6N2E2_4597 -6.4 -4.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3783 -6.4 -4.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_64 -6.0 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3253 -6.0 -4.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_5006 -5.8 -5.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4826 -5.8 -5.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4279 -5.7 -7.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3630 -5.7 -5.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4825 -5.7 -6.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4596 -5.6 -7.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -5.6 -5.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_50 -5.3 -8.1 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3751 -5.2 -11.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3264 -5.2 -3.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4047 -5.1 -3.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3060 -5.0 -4.3 Outer membrane protein H precursor compare
Pf6N2E2_3752 -5.0 -18.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5175 -5.0 -9.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3839 -4.9 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3826 -4.9 -5.8 Nitrogen regulation protein NR(I) compare
Pf6N2E2_3842 -4.8 -5.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2258 -4.8 -11.6 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5176 -4.8 -7.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5177 -4.8 -12.1 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3782 -4.7 -3.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2073 -4.6 -5.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -4.5 -11.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2885 -4.5 -5.4 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_77 -4.5 -5.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4048 -4.5 -8.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3610 -4.5 -5.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3251 -4.4 -11.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2588 -4.4 -4.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3252 -4.3 -9.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3554 -4.3 -10.3 GCN5-related N-acetyltransferase compare
Pf6N2E2_1186 -4.3 -6.4 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_1187 -4.2 -10.4 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_4278 -4.2 -12.3 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3461 -4.2 -2.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5150 -4.1 -6.8 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3072 -4.1 -11.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_658 -4.0 -11.4 sensor histidine kinase compare
Pf6N2E2_2074 -3.9 -2.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4564 -3.9 -8.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3825 -3.8 -6.3 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_66 -3.7 -7.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3841 -3.6 -6.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_63 -3.6 -6.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4353 -3.6 -5.6 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_4277 -3.5 -10.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2574 -3.5 -3.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_4372 -3.3 -5.1 FIG00460773: hypothetical protein compare
Pf6N2E2_3258 -3.3 -3.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1189 -3.3 -7.9 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_4759 -3.3 -15.8 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_1190 -3.3 -9.7 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_5527 -3.2 -3.1 Cold shock protein CspC compare
Pf6N2E2_2899 -3.2 -6.0 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4187 -3.2 -3.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3932 -3.2 -3.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2527 -3.2 -6.6 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3938 -3.1 -13.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4206 -3.1 -2.5 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3170 -3.1 -8.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4071 -3.1 -4.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_34 -3.0 -5.0 Cytosine deaminase (EC 3.5.4.1) conserved
Pf6N2E2_5156 -3.0 -2.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_6090 -2.9 -3.0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf6N2E2_2897 -2.9 -10.3 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_1056 -2.8 -1.7 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_5160 -2.8 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_5579 -2.8 -7.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5014 -2.8 -1.7 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3661 -2.8 -6.3 hypothetical protein compare
Pf6N2E2_2896 -2.7 -4.9 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_2181 -2.7 -2.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_1188 -2.7 -5.7 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_2895 -2.6 -8.6 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_2261 -2.6 -7.5 VacJ-like lipoprotein precursor compare
Pf6N2E2_3464 -2.6 -10.0 LysR family transcriptional regulator PA0133 compare
Pf6N2E2_4611 -2.5 -5.0 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4276 -2.5 -6.2 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3984 -2.5 -11.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4797 -2.5 -2.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4009 -2.5 -9.3 GGDEF domain protein compare
Pf6N2E2_4803 -2.5 -2.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_302 -2.4 -4.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2117 -2.3 -13.0 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_2891 -2.3 -12.0 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_3463 -2.3 -8.3 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) conserved
Pf6N2E2_178 -2.3 -1.7 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5242 -2.3 -2.8 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5337 -2.2 -4.8 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3257 -2.2 -4.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4352 -2.2 -2.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_6140 -2.2 -1.4 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_5338 -2.2 -7.9 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_2892 -2.1 -9.6 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_4763 -2.1 -10.5 Biotin synthesis protein BioC compare
Pf6N2E2_5679 -2.1 -4.2 hypothetical protein compare
Pf6N2E2_500 -2.1 -2.9 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_464 -2.1 -3.5 Sensory histidine kinase QseC compare
Pf6N2E2_2890 -2.0 -8.3 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_2893 -2.0 -6.5 hypothetical protein compare
Pf6N2E2_1191 -2.0 -8.1 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_1672 -2.0 -9.5 hypothetical protein compare
Pf6N2E2_3074 -2.0 -2.4 FIG00960973: hypothetical protein compare
Pf6N2E2_4638 -2.0 -2.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2465 -1.9 -5.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2218 -1.9 -4.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5316 -1.9 -2.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2888 -1.9 -9.6 Glucose-selective porin OprB compare
Pf6N2E2_2186 -1.8 -5.8 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3869 -1.8 -9.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_5666 -1.8 -9.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4579 -1.8 -2.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3885 -1.8 -2.6 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_4416 -1.8 -2.9 Tyrosine recombinase XerC compare
Pf6N2E2_4418 -1.8 -1.4 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2889 -1.8 -8.9 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_3786 -1.8 -2.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_5339 -1.8 -6.1 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_2274 -1.8 -4.8 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_4391 -1.8 -6.0 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_2473 -1.8 -1.5 Major outer membrane lipoprotein I compare
Pf6N2E2_5780 -1.8 -6.9 Periplasmic protease compare
Pf6N2E2_5494 -1.8 -3.5 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5406 -1.7 -2.5 FIG00958224: hypothetical protein compare
Pf6N2E2_2938 -1.7 -3.4 Outer membrane lipoprotein compare
Pf6N2E2_2340 -1.7 -3.7 Transcriptional regulator, GntR family compare
Pf6N2E2_828 -1.6 -5.3 Transcriptional regulator, TetR family compare
Pf6N2E2_4761 -1.6 -9.2 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5554 -1.6 -4.8 FIG023103: Predicted transmembrane protein compare
Pf6N2E2_4160 -1.6 -1.4 Cytochrome c5 compare
Pf6N2E2_3908 -1.6 -5.6 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3132 -1.6 -3.1 FIG00954548: hypothetical protein compare
Pf6N2E2_4453 -1.6 -11.2 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2552 -1.6 -5.0 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_496 -1.5 -8.3 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) conserved
Pf6N2E2_2514 -1.5 -3.7 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_499 -1.5 -5.3 Possible pyrimidine permease in reductive pathway conserved
Pf6N2E2_5103 -1.5 -1.4 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5001 -1.5 -1.9 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_498 -1.5 -6.4 Dihydropyrimidinase (EC 3.5.2.2) (from data) conserved
Pf6N2E2_2012 -1.5 -2.5 hypothetical protein compare
Pf6N2E2_37 -1.5 -3.6 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_2310 -1.5 -8.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3607 -1.5 -6.2 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2864 -1.4 -2.3 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_146 -1.4 -1.8 Transcriptional regulator, MarR family compare
Pf6N2E2_6164 -1.4 -1.3 tRNA-Val-TAC compare
Pf6N2E2_2474 -1.4 -6.2 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_5219 -1.4 -6.3 FIG140336: TPR domain protein compare
Pf6N2E2_5178 -1.4 -1.8 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4454 -1.4 -4.3 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_4987 -1.4 -1.5 MaoC-like domain protein compare
Pf6N2E2_497 -1.4 -4.0 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism conserved
Pf6N2E2_2180 -1.4 -3.1 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4659 -1.4 -4.0 Lipoprotein, putative compare
Pf6N2E2_3198 -1.4 -2.0 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2863 -1.4 -5.5 Gluconate permease compare
Pf6N2E2_3260 -1.4 -3.5 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2018 -1.4 -2.9 hypothetical protein compare
Pf6N2E2_3469 -1.4 -7.1 Nucleoside ABC transporter, permease protein 2 conserved
Pf6N2E2_2253 -1.4 -2.1 hypothetical protein compare
Pf6N2E2_2470 -1.4 -5.7 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf6N2E2_5761 -1.4 -1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_1072 -1.4 -4.7 LmbE-like protein compare
Pf6N2E2_3770 -1.4 -2.5 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3467 -1.3 -5.6 ABC transporter ATP-binding protein conserved
Pf6N2E2_5536 -1.3 -1.5 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3655 -1.3 -7.8 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_1606 -1.3 -5.2 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_3468 -1.3 -8.0 Nucleoside ABC transporter, permease protein 1 conserved
Pf6N2E2_5524 -1.3 -6.9 Outer membrane porin, OprD family compare
Pf6N2E2_863 -1.3 -4.8 Transcriptional regulator, IclR family compare
Pf6N2E2_89 -1.3 -2.0 hypothetical protein compare
Pf6N2E2_2311 -1.3 -5.7 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_3664 -1.3 -6.1 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_2530 -1.3 -6.8 Sensory box/GGDEF family protein compare
Pf6N2E2_2264 -1.3 -3.5 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_4764 -1.3 -3.5 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2746 -1.2 -3.8 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_4205 -1.2 -3.2 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5340 -1.2 -3.8 Stringent starvation protein A compare
Pf6N2E2_1656 -1.2 -2.4 hypothetical protein compare
Pf6N2E2_1605 -1.2 -6.1 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_2488 -1.2 -2.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4159 -1.2 -2.2 Cytochrome c4 compare
Pf6N2E2_3666 -1.2 -3.3 InaA protein compare
Pf6N2E2_5919 -1.2 -2.7 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_3325 -1.2 -1.7 ABC transporter, ATP-binding protein compare
Pf6N2E2_4658 -1.1 -4.4 FIG00955006: hypothetical protein compare
Pf6N2E2_5155 -1.1 -2.5 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5816 -1.1 -1.4 Smr domain protein compare
Pf6N2E2_2388 -1.1 -2.1 Esterase/lipase/thioesterase family protein compare
Pf6N2E2_4631 -1.1 -5.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3183 -1.1 -2.7 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_5584 -1.1 -2.6 Bacterioferritin-associated ferredoxin compare


Specific Phenotypes

For 14 genes in this experiment

For nitrogen source Cytosine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Cytosine across organisms