Experiment setAIT089 for Pseudomonas fluorescens FW300-N2E2

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Cytidine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.5 -4.5 Probable transmembrane protein compare
Pf6N2E2_3060 -6.4 -4.4 Outer membrane protein H precursor compare
Pf6N2E2_3630 -5.9 -4.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_64 -5.8 -4.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3253 -5.8 -4.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4825 -5.7 -5.5 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4597 -5.7 -6.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -5.6 -5.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5177 -5.6 -6.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3783 -5.6 -5.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4353 -5.5 -5.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_3842 -5.5 -3.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4071 -5.5 -3.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_77 -5.5 -3.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_71 -5.4 -5.3 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5006 -5.4 -6.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4596 -5.3 -7.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3751 -5.3 -9.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3251 -5.2 -8.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2588 -5.2 -3.6 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3940 -5.1 -7.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2258 -5.0 -9.0 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4278 -5.0 -10.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2899 -5.0 -4.8 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3264 -5.0 -3.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4279 -4.9 -10.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_1187 -4.7 -8.4 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_4047 -4.6 -4.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5175 -4.6 -10.3 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_2073 -4.6 -3.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_50 -4.5 -8.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3826 -4.5 -5.3 Nitrogen regulation protein NR(I) compare
Pf6N2E2_658 -4.4 -12.7 sensor histidine kinase compare
Pf6N2E2_3252 -4.4 -7.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3752 -4.3 -19.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5176 -4.3 -8.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4564 -4.3 -11.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3841 -4.3 -5.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5150 -4.3 -5.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3839 -4.3 -4.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3610 -4.2 -5.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4048 -4.2 -8.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3072 -4.2 -9.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_3938 -4.2 -14.4 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2885 -4.1 -5.6 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3554 -4.1 -9.8 GCN5-related N-acetyltransferase compare
Pf6N2E2_1186 -4.1 -6.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_4372 -4.0 -3.9 FIG00460773: hypothetical protein compare
Pf6N2E2_5014 -4.0 -1.7 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_66 -4.0 -9.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4277 -3.9 -12.4 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3782 -3.9 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3932 -3.8 -5.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4759 -3.8 -15.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_2074 -3.8 -2.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4803 -3.7 -2.5 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3825 -3.7 -6.0 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4276 -3.7 -5.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5160 -3.6 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3074 -3.5 -2.1 FIG00960973: hypothetical protein compare
Pf6N2E2_4159 -3.4 -4.4 Cytochrome c4 compare
Pf6N2E2_3258 -3.4 -3.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1189 -3.3 -7.2 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_63 -3.3 -5.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2219 -3.3 -2.2 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3941 -3.2 -3.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2186 -3.2 -7.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2261 -3.2 -4.9 VacJ-like lipoprotein precursor compare
Pf6N2E2_2896 -3.2 -5.3 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_2176 -3.1 -3.6 Amidases related to nicotinamidase compare
Pf6N2E2_5579 -3.1 -9.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3300 -3.1 -3.6 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_3885 -3.1 -4.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_1188 -3.0 -5.6 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_302 -3.0 -6.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5339 -3.0 -8.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_2574 -2.9 -2.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_1694 -2.9 -2.1 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_2527 -2.9 -6.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3170 -2.9 -8.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4187 -2.8 -3.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5780 -2.8 -9.9 Periplasmic protease compare
Pf6N2E2_3257 -2.7 -4.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5156 -2.7 -1.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2473 -2.7 -1.6 Major outer membrane lipoprotein I compare
Pf6N2E2_1056 -2.7 -1.5 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1190 -2.6 -7.4 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_2530 -2.6 -10.7 Sensory box/GGDEF family protein compare
Pf6N2E2_2897 -2.6 -9.9 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_34 -2.6 -5.6 Cytosine deaminase (EC 3.5.4.1) conserved
Pf6N2E2_5679 -2.6 -3.4 hypothetical protein compare
Pf6N2E2_5337 -2.5 -4.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_2117 -2.5 -13.3 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_70 -2.5 -4.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2706 -2.5 -2.5 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_5219 -2.4 -9.0 FIG140336: TPR domain protein compare
Pf6N2E2_5728 -2.4 -4.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2274 -2.4 -5.9 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3260 -2.4 -4.5 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5554 -2.3 -5.5 FIG023103: Predicted transmembrane protein compare
Pf6N2E2_5338 -2.3 -9.3 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5494 -2.3 -5.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4678 -2.3 -1.4 hypothetical protein compare
Pf6N2E2_2188 -2.3 -3.8 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_3607 -2.3 -8.1 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_4797 -2.3 -1.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3984 -2.3 -9.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4638 -2.3 -2.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3677 -2.2 -11.0 Sensory box/GGDEF family protein compare
Pf6N2E2_5527 -2.2 -2.9 Cold shock protein CspC compare
Pf6N2E2_4077 -2.1 -2.1 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_760 -2.1 -11.7 Na+/H+ antiporter NhaB compare
Pf6N2E2_2218 -2.1 -4.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3198 -2.1 -2.7 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2311 -2.1 -7.8 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_1424 -2.1 -2.5 transcriptional regulator, TetR family compare
Pf6N2E2_1191 -2.0 -6.7 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_3460 -2.0 -1.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_6164 -2.0 -1.4 tRNA-Val-TAC compare
Pf6N2E2_4636 -2.0 -7.4 periplasmic binding protein, putative compare
Pf6N2E2_3786 -2.0 -3.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_4611 -2.0 -3.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2309 -1.9 -2.4 hypothetical protein compare
Pf6N2E2_2552 -1.9 -4.5 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_146 -1.9 -2.5 Transcriptional regulator, MarR family compare
Pf6N2E2_4049 -1.9 -7.4 Glycine cleavage system transcriptional activator compare
Pf6N2E2_3349 -1.9 -2.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2892 -1.9 -10.0 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_2852 -1.9 -8.3 GGDEF domain/EAL domain protein compare
Pf6N2E2_3666 -1.9 -3.7 InaA protein compare
Pf6N2E2_1606 -1.8 -5.9 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_4009 -1.8 -8.2 GGDEF domain protein compare
Pf6N2E2_2465 -1.8 -3.5 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5103 -1.8 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4987 -1.8 -1.5 MaoC-like domain protein compare
Pf6N2E2_5111 -1.8 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5666 -1.8 -7.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2340 -1.7 -4.7 Transcriptional regulator, GntR family compare
Pf6N2E2_2889 -1.7 -7.2 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_2310 -1.7 -8.2 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_4072 -1.7 -3.9 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3696 -1.7 -1.4 hypothetical protein compare
Pf6N2E2_4476 -1.7 -5.4 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_2891 -1.6 -9.4 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_2732 -1.6 -5.4 Transcriptional regulator, LysR family compare
Pf6N2E2_3463 -1.6 -7.1 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) conserved
Pf6N2E2_5775 -1.6 -3.2 FOG: TPR repeat, SEL1 subfamily compare
Pf6N2E2_6090 -1.6 -2.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf6N2E2_2888 -1.6 -7.9 Glucose-selective porin OprB compare
Pf6N2E2_5277 -1.6 -5.5 FIG00953110: hypothetical protein compare
Pf6N2E2_2068 -1.5 -7.2 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3835 -1.5 -2.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3183 -1.5 -2.2 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2938 -1.5 -3.5 Outer membrane lipoprotein compare
Pf6N2E2_234 -1.5 -1.5 FIG00454312: hypothetical protein compare
Pf6N2E2_3461 -1.5 -1.6 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1932 -1.5 -4.5 Transcriptional regulator, IclR family compare
Pf6N2E2_2707 -1.5 -3.7 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_1673 -1.5 -2.1 Transcriptional regulator, TetR family compare
Pf6N2E2_5406 -1.5 -2.5 FIG00958224: hypothetical protein compare
Pf6N2E2_2317 -1.5 -3.6 Putative analog of CcoH, COG3198 compare
Pf6N2E2_2312 -1.5 -2.5 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_2746 -1.5 -5.5 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_863 -1.5 -4.5 Transcriptional regulator, IclR family compare
Pf6N2E2_5555 -1.5 -1.3 Cold shock protein CspA compare
Pf6N2E2_2314 -1.4 -1.8 VapB protein (antitoxin to VapC) compare
Pf6N2E2_828 -1.4 -4.2 Transcriptional regulator, TetR family compare
Pf6N2E2_2790 -1.4 -2.5 Helix-turn-helix motif compare
Pf6N2E2_2895 -1.4 -5.8 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_148 -1.4 -5.8 Membrane fusion component of tripartite multidrug resistance system compare
Pf6N2E2_3285 -1.4 -3.1 Rod shape-determining protein MreD compare
Pf6N2E2_149 -1.4 -6.6 Inner membrane component of tripartite multidrug resistance system compare
Pf6N2E2_6065 -1.4 -2.7 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_2313 -1.4 -2.7 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_4453 -1.4 -9.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_1072 -1.3 -5.2 LmbE-like protein compare
Pf6N2E2_2893 -1.3 -4.1 hypothetical protein compare
Pf6N2E2_37 -1.3 -3.0 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_3869 -1.3 -6.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_4394 -1.3 -5.2 Putrescine utilization regulator compare
Pf6N2E2_2864 -1.3 -2.2 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_5299 -1.3 -4.7 Benzoate transport protein compare
Pf6N2E2_2890 -1.3 -6.7 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_51 -1.3 -4.3 hypothetical protein compare
Pf6N2E2_2470 -1.3 -4.9 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf6N2E2_608 -1.3 -5.0 Transcriptional regulator of the arabinose operon in Shewanella, GntR family compare
Pf6N2E2_3323 -1.3 -3.1 hypothetical protein compare
Pf6N2E2_2180 -1.3 -2.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_238 -1.3 -1.8 hypothetical protein compare
Pf6N2E2_4601 -1.3 -2.2 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_5188 -1.3 -2.8 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4162 -1.3 -2.7 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4399 -1.3 -4.6 GGDEF domain/EAL domain protein compare
Pf6N2E2_3373 -1.3 -1.7 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_4659 -1.2 -3.5 Lipoprotein, putative compare
Pf6N2E2_178 -1.2 -1.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5340 -1.2 -2.8 Stringent starvation protein A compare
Pf6N2E2_3325 -1.2 -2.3 ABC transporter, ATP-binding protein compare
Pf6N2E2_4824 -1.2 -2.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_2474 -1.2 -6.2 ErfK/YbiS/YcfS/YnhG family protein compare


Specific Phenotypes

For 26 genes in this experiment

For nitrogen source Cytidine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Cytidine across organisms