Experiment setAIT087 for Pseudomonas fluorescens FW300-N2E2

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Parabanic Acid nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.9 -4.8 Probable transmembrane protein compare
Pf6N2E2_3573 -6.1 -6.0 HupE-UreJ family metal transporter compare
Pf6N2E2_4597 -5.5 -9.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5006 -5.3 -8.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3253 -5.3 -7.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4596 -5.2 -10.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3826 -5.1 -6.1 Nitrogen regulation protein NR(I) compare
Pf6N2E2_4825 -5.0 -9.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4826 -4.9 -8.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5176 -4.8 -9.1 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3839 -4.8 -4.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4047 -4.7 -6.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_64 -4.7 -4.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_2258 -4.6 -12.6 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3610 -4.4 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3751 -4.4 -15.2 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3552 -4.3 -11.4 Urease accessory protein UreD conserved
Pf6N2E2_3252 -4.3 -10.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_77 -4.3 -6.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5014 -4.3 -1.7 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5175 -4.2 -15.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3072 -4.1 -12.9 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_5177 -4.1 -11.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3752 -4.1 -22.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3782 -4.1 -4.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_71 -4.0 -8.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4564 -3.9 -9.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_1187 -3.9 -10.2 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_4048 -3.9 -8.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3571 -3.9 -3.8 Urease accessory protein UreF compare
Pf6N2E2_3630 -3.9 -6.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3553 -3.8 -8.0 Urease (EC 3.5.1.5) (from data) conserved
Pf6N2E2_3841 -3.7 -7.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3842 -3.6 -5.5 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4417 -3.6 -5.9 Protein of unknown function DUF484 compare
Pf6N2E2_3572 -3.5 -14.0 Urease accessory protein UreG conserved
Pf6N2E2_66 -3.5 -8.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3783 -3.5 -6.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3932 -3.5 -5.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4206 -3.5 -3.1 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3940 -3.4 -11.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1186 -3.3 -8.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2885 -3.3 -9.0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2074 -3.2 -2.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4372 -3.2 -6.1 FIG00460773: hypothetical protein compare
Pf6N2E2_2073 -3.2 -9.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3556 -3.2 -8.8 Urease (EC 3.5.1.5) (from data) compare
Pf6N2E2_4353 -3.1 -4.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_4803 -3.1 -3.0 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3938 -2.9 -12.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3825 -2.9 -4.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_3251 -2.9 -11.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3027 -2.8 -2.1 Baseplate assembly protein V compare
Pf6N2E2_5156 -2.8 -2.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3461 -2.8 -1.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5262 -2.8 -2.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_2218 -2.7 -5.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_658 -2.7 -11.9 sensor histidine kinase compare
Pf6N2E2_4418 -2.7 -1.5 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_5527 -2.7 -3.5 Cold shock protein CspC compare
Pf6N2E2_3554 -2.7 -6.6 GCN5-related N-acetyltransferase compare
Pf6N2E2_2897 -2.7 -10.5 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5579 -2.6 -6.8 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_50 -2.6 -6.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5536 -2.5 -1.7 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5316 -2.5 -2.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4638 -2.5 -2.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5299 -2.4 -8.9 Benzoate transport protein compare
Pf6N2E2_3460 -2.4 -2.3 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_6140 -2.4 -1.3 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_2864 -2.4 -2.9 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_3570 -2.4 -3.1 Urease accessory protein UreE conserved
Pf6N2E2_63 -2.4 -3.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3170 -2.3 -6.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2465 -2.2 -4.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_613 -2.2 -2.1 lipoprotein, putative compare
Pf6N2E2_2217 -2.2 -4.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5150 -2.2 -6.2 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2588 -2.2 -3.8 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3984 -2.1 -10.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4276 -2.1 -6.4 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4278 -2.1 -9.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_1190 -2.1 -4.8 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_4624 -2.0 -1.3 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_1188 -2.0 -4.2 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_5001 -2.0 -2.2 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_4759 -2.0 -11.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4279 -1.9 -9.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_2586 -1.9 -2.3 Hpt domain protein compare
Pf6N2E2_1189 -1.9 -5.4 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_4277 -1.9 -7.6 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2253 -1.9 -4.2 hypothetical protein compare
Pf6N2E2_5571 -1.8 -2.0 hypothetical protein compare
Pf6N2E2_4009 -1.8 -7.5 GGDEF domain protein compare
Pf6N2E2_2574 -1.8 -2.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_2869 -1.8 -2.1 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_5219 -1.7 -6.3 FIG140336: TPR domain protein compare
Pf6N2E2_2509 -1.7 -2.6 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3828 -1.7 -3.6 tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) compare
Pf6N2E2_1673 -1.7 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_5494 -1.7 -5.4 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5190 -1.6 -7.5 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_4476 -1.6 -6.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3568 -1.6 -3.4 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_5508 -1.6 -1.9 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_4661 -1.5 -2.6 KluA regulatory protein compare
Pf6N2E2_3849 -1.5 -2.8 FIG00954739: hypothetical protein compare
Pf6N2E2_3039 -1.5 -5.0 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_4205 -1.5 -3.4 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4181 -1.4 -1.3 Organic hydroperoxide resistance protein compare
Pf6N2E2_2891 -1.4 -8.6 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_2473 -1.4 -1.2 Major outer membrane lipoprotein I compare
Pf6N2E2_4416 -1.4 -2.3 Tyrosine recombinase XerC compare
Pf6N2E2_4928 -1.4 -1.8 Permeases of the major facilitator superfamily compare
Pf6N2E2_3529 -1.4 -1.9 Toxin A compare
Pf6N2E2_302 -1.4 -3.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5520 -1.4 -5.7 Sensory box histidine kinase compare
Pf6N2E2_2756 -1.4 -5.3 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2863 -1.4 -5.6 Gluconate permease compare
Pf6N2E2_2340 -1.4 -3.2 Transcriptional regulator, GntR family compare
Pf6N2E2_2899 -1.4 -4.5 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5666 -1.3 -6.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4025 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_3969 -1.3 -1.8 Membrane-fusion protein compare
Pf6N2E2_51 -1.3 -5.9 hypothetical protein compare
Pf6N2E2_3661 -1.3 -4.8 hypothetical protein compare
Pf6N2E2_3338 -1.3 -2.4 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_2508 -1.3 -2.7 hypothetical protein compare
Pf6N2E2_5564 -1.3 -8.1 Membrane protein glpM conserved
Pf6N2E2_3305 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_2442 -1.2 -6.5 sensor histidine kinase/response regulator compare
Pf6N2E2_70 -1.2 -2.7 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3033 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_5667 -1.2 -4.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_692 -1.2 -3.4 Glucarate dehydratase (EC 4.2.1.40) compare
Pf6N2E2_2871 -1.2 -2.8 FIG00954271: hypothetical protein compare
Pf6N2E2_3555 -1.2 -2.8 Tabtoxin resistance protein compare
Pf6N2E2_3134 -1.1 -1.1 hypothetical protein compare
Pf6N2E2_4364 -1.1 -1.9 Protein YicC compare
Pf6N2E2_2892 -1.1 -6.4 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_2675 -1.1 -1.0 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2852 -1.1 -5.8 GGDEF domain/EAL domain protein compare
Pf6N2E2_3659 -1.1 -3.6 Protein fixF compare
Pf6N2E2_2753 -1.1 -2.3 HtrA protease/chaperone protein compare
Pf6N2E2_3658 -1.1 -5.0 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_5111 -1.1 -1.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5242 -1.1 -1.9 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4636 -1.1 -5.4 periplasmic binding protein, putative compare
Pf6N2E2_6099 -1.0 -1.1 tRNA-Glu-TTC compare
Pf6N2E2_2080 -1.0 -1.0 hypothetical protein compare
Pf6N2E2_5524 -1.0 -6.7 Outer membrane porin, OprD family compare
Pf6N2E2_5331 -1.0 -3.6 ATPase, AFG1 family compare
Pf6N2E2_1545 -1.0 -3.5 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3258 -1.0 -3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3635 -1.0 -1.9 FIG00953138: hypothetical protein compare
Pf6N2E2_3257 -1.0 -2.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3696 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_2895 -1.0 -4.8 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_3095 -1.0 -0.9 hypothetical protein compare
Pf6N2E2_2285 -1.0 -1.3 FIG00954079: hypothetical protein compare
Pf6N2E2_3060 -1.0 -1.8 Outer membrane protein H precursor compare
Pf6N2E2_1694 -1.0 -1.2 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_5746 -1.0 -1.7 Cobalamin synthase compare
Pf6N2E2_2889 -1.0 -5.7 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_4071 -1.0 -2.1 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2890 -1.0 -4.2 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_737 -1.0 -1.7 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_1490 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_1932 -1.0 -3.3 Transcriptional regulator, IclR family compare
Pf6N2E2_2896 -1.0 -3.2 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_3040 -0.9 -4.4 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2474 -0.9 -4.9 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_4611 -0.9 -2.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_1191 -0.9 -4.4 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_4824 -0.9 -2.6 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_3429 -0.9 -1.7 hypothetical protein compare
Pf6N2E2_4453 -0.9 -7.1 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3677 -0.9 -6.0 Sensory box/GGDEF family protein compare
Pf6N2E2_5756 -0.9 -1.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3260 -0.9 -3.2 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2428 -0.9 -2.3 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_5943 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_2448 -0.9 -2.6 Thiopurine S-methyltransferase (EC 2.1.1.67) compare
Pf6N2E2_2186 -0.9 -2.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3454 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_1294 -0.9 -1.7 Carbon starvation protein A compare
Pf6N2E2_4658 -0.9 -2.9 FIG00955006: hypothetical protein compare
Pf6N2E2_1606 -0.9 -3.5 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_3351 -0.9 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5780 -0.9 -4.3 Periplasmic protease compare
Pf6N2E2_672 -0.9 -1.5 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_4162 -0.9 -1.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_291 -0.9 -3.3 ATP-dependent Clp protease adaptor protein ClpS compare
Pf6N2E2_28 -0.9 -2.2 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_5919 -0.9 -1.6 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_5160 -0.9 -0.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2855 -0.8 -2.0 DGPFAETKE compare
Pf6N2E2_2795 -0.8 -1.9 putative exported protein compare
Pf6N2E2_5727 -0.8 -2.8 FIG00955360: hypothetical protein compare
Pf6N2E2_3592 -0.8 -4.4 Protein containing transglutaminase-like domain, putative cysteine protease compare


Specific Phenotypes

For 6 genes in this experiment

For nitrogen source Parabanic Acid in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Parabanic Acid across organisms