Experiment setAIT078 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.6 -4.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_477 -6.3 -4.3 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_3842 -6.0 -4.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3253 -5.5 -6.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2258 -5.5 -9.9 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4826 -5.5 -7.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4596 -5.5 -9.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3248 -5.4 -6.3 Probable transmembrane protein compare
Pf6N2E2_5177 -5.3 -10.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4825 -5.3 -8.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4279 -5.3 -12.2 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_64 -5.2 -5.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3783 -5.1 -6.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_77 -5.1 -6.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_71 -5.1 -6.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5006 -5.1 -9.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4636 -5.0 -10.1 periplasmic binding protein, putative compare
Pf6N2E2_2588 -4.9 -4.8 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4276 -4.9 -3.4 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4047 -4.9 -5.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4278 -4.9 -12.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_5176 -4.8 -9.2 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3826 -4.8 -6.6 Nitrogen regulation protein NR(I) compare
Pf6N2E2_50 -4.8 -10.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3839 -4.7 -4.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4071 -4.7 -5.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5175 -4.6 -13.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5150 -4.6 -6.2 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3782 -4.5 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3825 -4.5 -6.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_3885 -4.5 -4.4 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2885 -4.5 -6.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3170 -4.4 -15.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5275 -4.4 -9.4 putative membrane protein conserved
Pf6N2E2_3630 -4.3 -8.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5723 -4.3 -15.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5527 -4.2 -2.9 Cold shock protein CspC compare
Pf6N2E2_3072 -4.2 -12.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_3841 -4.2 -6.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4453 -4.1 -17.5 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4803 -4.1 -2.8 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_66 -4.0 -11.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3252 -3.9 -8.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5160 -3.9 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3940 -3.8 -12.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3932 -3.8 -6.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4759 -3.8 -17.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4048 -3.7 -7.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3264 -3.7 -4.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3661 -3.7 -6.1 hypothetical protein compare
Pf6N2E2_3251 -3.6 -13.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3610 -3.6 -4.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4372 -3.6 -6.8 FIG00460773: hypothetical protein compare
Pf6N2E2_3060 -3.6 -3.6 Outer membrane protein H precursor compare
Pf6N2E2_4072 -3.6 -4.9 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_5989 -3.6 -16.5 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) conserved
Pf6N2E2_4564 -3.5 -7.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5030 -3.5 -5.5 Transcriptional regulator, AsnC family compare
Pf6N2E2_5153 -3.5 -8.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2852 -3.4 -10.9 GGDEF domain/EAL domain protein compare
Pf6N2E2_4187 -3.3 -4.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5328 -3.3 -6.2 FIG00958649: hypothetical protein compare
Pf6N2E2_6064 -3.3 -7.8 2-methylaconitate isomerase compare
Pf6N2E2_6063 -3.3 -9.6 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_5520 -3.1 -8.2 Sensory box histidine kinase compare
Pf6N2E2_4365 -3.1 -9.1 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_3461 -3.1 -2.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2863 -3.0 -8.5 Gluconate permease compare
Pf6N2E2_4160 -3.0 -1.7 Cytochrome c5 compare
Pf6N2E2_613 -2.9 -2.2 lipoprotein, putative compare
Pf6N2E2_4277 -2.9 -9.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2864 -2.9 -3.1 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_1056 -2.9 -1.5 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_5579 -2.8 -7.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5494 -2.8 -7.0 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5156 -2.8 -2.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2073 -2.8 -9.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4615 -2.8 -2.6 type IV pili signal transduction protein PilI compare
Pf6N2E2_658 -2.8 -11.2 sensor histidine kinase compare
Pf6N2E2_4810 -2.7 -9.0 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_2756 -2.7 -8.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5242 -2.7 -3.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2074 -2.6 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3586 -2.6 -8.0 NAD synthetase (EC 6.3.1.5) compare
Pf6N2E2_3062 -2.5 -5.4 Membrane-associated zinc metalloprotease compare
Pf6N2E2_1147 -2.5 -4.3 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_5331 -2.4 -7.5 ATPase, AFG1 family compare
Pf6N2E2_481 -2.4 -8.6 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) conserved
Pf6N2E2_3984 -2.3 -10.8 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2442 -2.3 -13.5 sensor histidine kinase/response regulator compare
Pf6N2E2_6061 -2.3 -9.1 Methylisocitrate lyase (EC 4.1.3.30) (from data) compare
Pf6N2E2_63 -2.3 -3.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4057 -2.2 -1.2 lipoprotein, putative compare
Pf6N2E2_1932 -2.2 -5.7 Transcriptional regulator, IclR family compare
Pf6N2E2_5728 -2.2 -4.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2887 -2.2 -5.1 Aldose 1-epimerase compare
Pf6N2E2_4618 -2.1 -5.7 Chemotaxis signal transduction protein compare
Pf6N2E2_2753 -2.1 -3.3 HtrA protease/chaperone protein compare
Pf6N2E2_2526 -2.1 -5.3 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_5045 -2.1 -11.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_482 -2.1 -4.2 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_4364 -2.0 -3.7 Protein YicC compare
Pf6N2E2_2340 -2.0 -5.4 Transcriptional regulator, GntR family compare
Pf6N2E2_2899 -2.0 -4.3 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4614 -2.0 -3.8 twitching motility protein PilH compare
Pf6N2E2_4009 -2.0 -7.9 GGDEF domain protein compare
Pf6N2E2_4638 -1.9 -2.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5316 -1.9 -2.4 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4611 -1.9 -3.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2465 -1.9 -7.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2218 -1.9 -5.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4362 -1.9 -2.8 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_3270 -1.9 -3.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2896 -1.9 -4.4 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_2519 -1.9 -1.8 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_4764 -1.9 -5.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_479 -1.9 -4.3 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_5157 -1.8 -9.6 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2274 -1.8 -6.1 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3198 -1.8 -2.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_5219 -1.8 -6.5 FIG140336: TPR domain protein compare
Pf6N2E2_2549 -1.7 -1.8 hypothetical protein compare
Pf6N2E2_5001 -1.7 -2.5 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_480 -1.7 -9.7 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4) (from data) conserved
Pf6N2E2_4710 -1.7 -2.1 hypothetical protein compare
Pf6N2E2_3283 -1.6 -4.3 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_4761 -1.6 -7.6 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5111 -1.6 -2.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2186 -1.6 -4.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5705 -1.6 -1.8 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_1146 -1.6 -5.1 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) conserved
Pf6N2E2_3521 -1.6 -6.2 Sensor histidine kinase/response regulator compare
Pf6N2E2_1617 -1.6 -1.2 COG2199: FOG: GGDEF domain compare
Pf6N2E2_2530 -1.6 -8.8 Sensory box/GGDEF family protein compare
Pf6N2E2_4074 -1.6 -7.1 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_5394 -1.5 -2.6 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_51 -1.5 -5.2 hypothetical protein compare
Pf6N2E2_2124 -1.5 -1.6 Mg(2+) transport ATPase protein C compare
Pf6N2E2_2447 -1.5 -7.2 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5555 -1.5 -1.6 Cold shock protein CspA compare
Pf6N2E2_2281 -1.5 -2.7 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_3835 -1.5 -3.6 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_2586 -1.5 -2.1 Hpt domain protein compare
Pf6N2E2_2708 -1.5 -4.0 Lactam utilization protein LamB compare
Pf6N2E2_4416 -1.5 -2.6 Tyrosine recombinase XerC compare
Pf6N2E2_148 -1.5 -6.5 Membrane fusion component of tripartite multidrug resistance system compare
Pf6N2E2_2473 -1.4 -1.2 Major outer membrane lipoprotein I compare
Pf6N2E2_478 -1.4 -3.8 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) compare
Pf6N2E2_1859 -1.4 -2.3 hypothetical protein compare
Pf6N2E2_4399 -1.4 -5.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_3696 -1.4 -1.4 hypothetical protein compare
Pf6N2E2_6100 -1.4 -2.5 tRNA-Val-TAC compare
Pf6N2E2_6062 -1.4 -6.0 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_1694 -1.4 -1.6 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_149 -1.3 -7.1 Inner membrane component of tripartite multidrug resistance system compare
Pf6N2E2_3349 -1.3 -1.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2188 -1.3 -3.7 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_1138 -1.3 -4.6 Transcriptional regulator, AraC family conserved
Pf6N2E2_2897 -1.3 -6.5 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5943 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_828 -1.3 -3.8 Transcriptional regulator, TetR family compare
Pf6N2E2_75 -1.3 -3.4 Colicin V production protein compare
Pf6N2E2_2895 -1.3 -5.6 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_4476 -1.3 -5.3 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_5420 -1.3 -4.5 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf6N2E2_4631 -1.3 -6.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_288 -1.3 -1.9 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2707 -1.3 -3.1 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_5158 -1.3 -4.0 FIG00954153: hypothetical protein compare
Pf6N2E2_3677 -1.3 -8.3 Sensory box/GGDEF family protein compare
Pf6N2E2_5544 -1.3 -4.9 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_4412 -1.2 -6.7 Ammonium transporter compare
Pf6N2E2_4205 -1.2 -3.1 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5845 -1.2 -5.2 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_4747 -1.2 -2.4 Transmembrane sensor compare
Pf6N2E2_2892 -1.2 -7.4 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_4617 -1.2 -8.2 Signal transduction histidine kinase CheA (EC 2.7.3.-) compare
Pf6N2E2_3655 -1.2 -7.4 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_434 -1.2 -2.3 hypothetical protein compare
Pf6N2E2_2189 -1.2 -4.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_2891 -1.2 -6.9 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_2714 -1.2 -1.7 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_5241 -1.2 -1.9 Aminopeptidase N compare
Pf6N2E2_922 -1.2 -2.2 FIG00794167: hypothetical protein compare
Pf6N2E2_3665 -1.2 -1.0 serine/threonine protein kinase compare
Pf6N2E2_4388 -1.2 -7.3 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf6N2E2_5846 -1.1 -6.3 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_4763 -1.1 -6.2 Biotin synthesis protein BioC compare
Pf6N2E2_3282 -1.1 -2.0 FIG005080: Possible exported protein compare
Pf6N2E2_4579 -1.1 -1.6 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_614 -1.1 -5.7 3-carboxymuconate cyclase compare
Pf6N2E2_3004 -1.1 -2.6 Prophage baseplate assembly protein V compare
Pf6N2E2_5430 -1.1 -5.7 Transglycosylase, Slt family compare
Pf6N2E2_2893 -1.1 -4.1 hypothetical protein compare
Pf6N2E2_2248 -1.1 -7.3 Aspartate racemase compare
Pf6N2E2_4417 -1.1 -3.1 Protein of unknown function DUF484 compare
Pf6N2E2_1391 -1.1 -3.2 DNA-binding response regulator, LuxR family compare
Pf6N2E2_5740 -1.1 -4.4 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_5255 -1.1 -5.9 Outer membrane stress sensor protease DegS compare
Pf6N2E2_1652 -1.1 -2.1 Transcriptional regulator, TetR family compare


Specific Phenotypes

For 24 genes in this experiment

For nitrogen source L-Isoleucine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Isoleucine across organisms