Experiment setAIT076 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Proline nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -7.1 -4.9 Probable transmembrane protein compare
Pf6N2E2_3060 -7.0 -4.8 Outer membrane protein H precursor compare
Pf6N2E2_3783 -6.8 -4.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3630 -6.5 -4.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_71 -6.5 -4.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4597 -6.4 -7.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -6.4 -6.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_64 -6.4 -4.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3842 -6.2 -4.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4596 -5.9 -9.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5006 -5.9 -8.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3253 -5.7 -7.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3264 -5.6 -3.8 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3932 -5.4 -7.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4826 -5.4 -9.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_5176 -5.3 -8.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_77 -5.2 -6.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3610 -5.0 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3839 -5.0 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3826 -4.9 -6.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_4047 -4.8 -7.4 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5175 -4.8 -14.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4048 -4.7 -9.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3685 -4.7 -15.9 Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) compare
Pf6N2E2_4759 -4.7 -18.2 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_2073 -4.7 -7.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5177 -4.6 -13.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3940 -4.5 -13.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5527 -4.5 -3.0 Cold shock protein CspC compare
Pf6N2E2_760 -4.4 -15.5 Na+/H+ antiporter NhaB compare
Pf6N2E2_4564 -4.4 -10.0 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3782 -4.3 -5.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_50 -4.2 -7.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3252 -4.1 -9.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2074 -4.1 -2.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3841 -4.0 -7.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4187 -4.0 -3.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4075 -3.9 -4.6 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_3251 -3.8 -12.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1186 -3.7 -7.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_302 -3.6 -6.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_66 -3.6 -8.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4353 -3.6 -7.3 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_2258 -3.6 -14.6 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2885 -3.5 -9.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_4072 -3.4 -5.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_1189 -3.3 -8.3 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_4762 -3.3 -4.6 Biotin synthesis protein BioH compare
Pf6N2E2_1187 -3.3 -11.3 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3665 -3.1 -1.8 serine/threonine protein kinase compare
Pf6N2E2_3938 -3.1 -17.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2465 -3.0 -6.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5156 -3.0 -2.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5579 -3.0 -8.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3198 -3.0 -3.4 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4279 -3.0 -13.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_1188 -2.9 -6.8 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_5316 -2.9 -2.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3072 -2.9 -12.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_3170 -2.8 -7.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3666 -2.8 -5.5 InaA protein compare
Pf6N2E2_6057 -2.7 -3.3 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_3684 -2.7 -12.7 Proline/sodium symporter PutP (TC 2.A.21.2.1) @ Propionate/sodium symporter conserved
Pf6N2E2_1694 -2.7 -2.4 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_4372 -2.6 -7.0 FIG00460773: hypothetical protein compare
Pf6N2E2_63 -2.6 -3.9 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5014 -2.6 -1.9 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3257 -2.6 -5.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4761 -2.5 -11.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2646 -2.4 -2.7 FIG00953416: hypothetical protein compare
Pf6N2E2_2261 -2.4 -8.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_2217 -2.4 -5.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5258 -2.4 -10.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4763 -2.4 -12.7 Biotin synthesis protein BioC compare
Pf6N2E2_3258 -2.3 -5.8 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3984 -2.3 -12.0 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3260 -2.3 -5.9 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3825 -2.2 -5.1 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2218 -2.2 -5.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4764 -2.2 -7.8 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2897 -2.2 -9.7 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_2186 -2.2 -7.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5950 -2.2 -3.2 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3261 -2.2 -5.6 hypothetical protein compare
Pf6N2E2_1190 -2.1 -6.2 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_5242 -2.1 -3.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5845 -2.1 -8.1 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_1191 -2.1 -8.5 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_3532 -2.1 -7.8 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_5746 -2.0 -4.2 Cobalamin synthase compare
Pf6N2E2_4797 -2.0 -3.0 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5780 -2.0 -9.2 Periplasmic protease compare
Pf6N2E2_4631 -2.0 -9.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_658 -2.0 -9.7 sensor histidine kinase compare
Pf6N2E2_4638 -2.0 -3.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4803 -2.0 -2.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2753 -1.9 -3.1 HtrA protease/chaperone protein compare
Pf6N2E2_3535 -1.9 -7.9 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_5406 -1.9 -3.5 FIG00958224: hypothetical protein compare
Pf6N2E2_3534 -1.9 -3.3 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_2706 -1.9 -4.1 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_5183 -1.9 -12.8 Paraquat-inducible protein B compare
Pf6N2E2_3554 -1.9 -8.5 GCN5-related N-acetyltransferase compare
Pf6N2E2_5679 -1.9 -3.9 hypothetical protein compare
Pf6N2E2_3460 -1.9 -1.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3300 -1.9 -2.6 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_5257 -1.9 -9.9 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4417 -1.8 -4.5 Protein of unknown function DUF484 compare
Pf6N2E2_4009 -1.8 -9.1 GGDEF domain protein compare
Pf6N2E2_5219 -1.8 -7.1 FIG140336: TPR domain protein compare
Pf6N2E2_3762 -1.8 -7.6 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5676 -1.7 -3.0 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_4071 -1.7 -5.5 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5728 -1.7 -3.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4074 -1.7 -8.1 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_3537 -1.7 -5.9 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_5252 -1.7 -2.8 FIG00956396: hypothetical protein compare
Pf6N2E2_2384 -1.7 -5.4 CmpX compare
Pf6N2E2_6058 -1.7 -4.9 FIG139976: hypothetical protein compare
Pf6N2E2_4278 -1.7 -7.7 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4611 -1.7 -4.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5181 -1.7 -9.7 Paraquat-inducible protein A compare
Pf6N2E2_3533 -1.6 -5.4 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_5846 -1.6 -10.2 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
Pf6N2E2_2588 -1.6 -3.6 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_51 -1.6 -5.1 hypothetical protein compare
Pf6N2E2_4464 -1.6 -3.1 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_3856 -1.6 -7.6 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) compare
Pf6N2E2_5738 -1.6 -8.4 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_3753 -1.6 -10.8 DamX, an inner membrane protein involved in bile resistance compare
Pf6N2E2_3461 -1.6 -1.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_4678 -1.6 -1.4 hypothetical protein compare
Pf6N2E2_2065 -1.6 -3.6 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2340 -1.6 -5.4 Transcriptional regulator, GntR family compare
Pf6N2E2_2825 -1.6 -4.9 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_3325 -1.6 -3.4 ABC transporter, ATP-binding protein compare
Pf6N2E2_2707 -1.6 -4.3 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_2274 -1.6 -5.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_863 -1.6 -5.5 Transcriptional regulator, IclR family compare
Pf6N2E2_4007 -1.6 -3.3 FIG00956018: hypothetical protein compare
Pf6N2E2_2888 -1.5 -7.9 Glucose-selective porin OprB compare
Pf6N2E2_2823 -1.5 -4.9 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_5745 -1.5 -6.3 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2835 -1.5 -2.8 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf6N2E2_5190 -1.5 -9.4 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_4352 -1.5 -3.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_5742 -1.5 -5.9 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_2068 -1.5 -8.0 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_4418 -1.4 -1.3 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_5182 -1.4 -5.4 Paraquat-inducible protein A compare
Pf6N2E2_3521 -1.4 -8.4 Sensor histidine kinase/response regulator compare
Pf6N2E2_2513 -1.4 -4.2 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2064 -1.4 -4.4 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3869 -1.4 -8.4 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_613 -1.4 -1.8 lipoprotein, putative compare
Pf6N2E2_3586 -1.3 -6.5 NAD synthetase (EC 6.3.1.5) compare
Pf6N2E2_3516 -1.3 -2.5 Probable transmembrane protein compare
Pf6N2E2_4097 -1.3 -7.0 FIG00953365: hypothetical protein compare
Pf6N2E2_4276 -1.3 -3.9 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3667 -1.3 -1.4 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_1652 -1.3 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_4394 -1.3 -6.2 Putrescine utilization regulator compare
Pf6N2E2_2574 -1.3 -1.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_3664 -1.3 -6.9 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_2699 -1.3 -5.8 Fe(2+)/alpha-ketoglutarate-dependent dioxygenase LpxO compare
Pf6N2E2_4205 -1.3 -3.2 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4174 -1.3 -7.9 Methionine ABC transporter substrate-binding protein compare
Pf6N2E2_5741 -1.3 -4.5 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_4168 -1.3 -4.8 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_4928 -1.3 -1.9 Permeases of the major facilitator superfamily compare
Pf6N2E2_70 -1.3 -3.6 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_5155 -1.2 -3.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2176 -1.2 -1.4 Amidases related to nicotinamidase compare
Pf6N2E2_3040 -1.2 -5.5 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2891 -1.2 -8.3 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_75 -1.2 -3.0 Colicin V production protein compare
Pf6N2E2_2010 -1.2 -2.0 hypothetical protein compare
Pf6N2E2_4987 -1.2 -1.5 MaoC-like domain protein compare
Pf6N2E2_5524 -1.2 -5.9 Outer membrane porin, OprD family compare
Pf6N2E2_2311 -1.2 -6.8 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_3349 -1.2 -1.9 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3039 -1.2 -4.9 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_2312 -1.2 -2.4 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_3074 -1.2 -2.0 FIG00960973: hypothetical protein compare
Pf6N2E2_4206 -1.2 -1.6 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2893 -1.2 -6.2 hypothetical protein compare
Pf6N2E2_2313 -1.2 -3.1 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_4451 -1.2 -4.8 FIG139438: lipoprotein B compare
Pf6N2E2_4025 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_2824 -1.1 -6.6 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_1032 -1.1 -1.3 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_5740 -1.1 -3.9 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_3323 -1.1 -3.3 hypothetical protein compare
Pf6N2E2_4416 -1.1 -2.0 Tyrosine recombinase XerC compare
Pf6N2E2_4453 -1.1 -9.4 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2059 -1.1 -2.9 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_5703 -1.1 -4.3 outer membrane protein H1 compare
Pf6N2E2_3134 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_2527 -1.1 -4.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_4159 -1.1 -3.8 Cytochrome c4 compare


Specific Phenotypes

For 10 genes in this experiment

For nitrogen source L-Proline in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Proline across organisms