Experiment setAIT068 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Histidine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_71 -6.2 -4.3 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_64 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4825 -6.0 -5.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3630 -5.8 -5.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_50 -5.6 -7.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3799 -5.5 -5.4 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
Pf6N2E2_5006 -5.5 -7.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4596 -5.5 -8.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4279 -5.4 -10.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4826 -5.4 -7.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4597 -5.3 -8.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4759 -5.3 -11.8 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3751 -5.3 -11.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3826 -5.3 -5.1 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5177 -5.1 -10.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_5175 -5.0 -9.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4047 -5.0 -4.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2258 -4.8 -10.8 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3248 -4.8 -5.4 Probable transmembrane protein compare
Pf6N2E2_5150 -4.8 -5.7 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3801 -4.7 -6.4 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
Pf6N2E2_2885 -4.6 -5.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_4761 -4.6 -12.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5176 -4.6 -8.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3752 -4.5 -21.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_66 -4.5 -10.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4278 -4.5 -13.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4564 -4.4 -9.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2073 -4.3 -7.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4764 -4.3 -7.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2899 -4.3 -7.0 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5014 -4.2 -1.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4048 -4.2 -7.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5527 -4.1 -2.8 Cold shock protein CspC compare
Pf6N2E2_77 -4.1 -6.2 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_63 -4.1 -7.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4762 -4.1 -4.4 Biotin synthesis protein BioH compare
Pf6N2E2_302 -4.0 -8.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2074 -4.0 -2.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4803 -3.9 -2.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3825 -3.9 -5.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4418 -3.9 -1.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4277 -3.8 -10.4 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3808 -3.7 -9.1 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) conserved
Pf6N2E2_3805 -3.7 -11.4 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
Pf6N2E2_4763 -3.7 -9.1 Biotin synthesis protein BioC compare
Pf6N2E2_3804 -3.6 -10.8 Cytosine/purine/uracil/thiamine/allantoin permease family protein conserved
Pf6N2E2_3798 -3.6 -8.7 Imidazolonepropionase (EC 3.5.2.7) (from data) conserved
Pf6N2E2_2897 -3.5 -11.1 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_4631 -3.4 -9.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3932 -3.3 -4.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4369 -3.2 -2.2 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_3803 -3.1 -8.6 Histidine ABC transporter, histidine-binding protein (TC 3.A.1) compare
Pf6N2E2_3797 -3.1 -9.5 N-formylglutamate deformylase (EC 3.5.1.68) (from data) conserved
Pf6N2E2_3800 -3.0 -5.1 Histidine ammonia-lyase (EC 4.3.1.3) compare
Pf6N2E2_5156 -3.0 -2.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3072 -2.9 -11.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_5103 -2.9 -1.7 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5950 -2.8 -5.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5579 -2.8 -7.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3170 -2.8 -7.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5190 -2.8 -12.1 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_5508 -2.8 -3.2 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_5494 -2.8 -6.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5316 -2.7 -2.6 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2465 -2.7 -5.0 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3802 -2.6 -3.8 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf6N2E2_3941 -2.6 -4.1 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5676 -2.5 -4.8 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5153 -2.5 -7.8 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2753 -2.5 -3.3 HtrA protease/chaperone protein compare
Pf6N2E2_2863 -2.4 -8.1 Gluconate permease compare
Pf6N2E2_3908 -2.4 -6.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4797 -2.3 -2.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_51 -2.2 -6.4 hypothetical protein compare
Pf6N2E2_3349 -2.2 -3.1 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4276 -2.2 -5.9 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4638 -2.2 -3.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3938 -2.2 -11.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2018 -2.1 -3.3 hypothetical protein compare
Pf6N2E2_5405 -2.1 -6.3 ABC transporter for D-Alanine, ATPase component (from data) conserved
Pf6N2E2_3198 -2.1 -2.8 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2574 -2.0 -2.1 Flagellar synthesis regulator FleN compare
Pf6N2E2_4206 -2.0 -2.4 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3534 -2.0 -3.4 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_4187 -1.9 -4.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_1718 -1.9 -2.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_37 -1.9 -3.9 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_3984 -1.9 -9.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5403 -1.8 -8.9 ABC transporter for D-Alanine, permease component 2 (from data) conserved
Pf6N2E2_4153 -1.8 -1.8 Sensory box histidine kinase compare
Pf6N2E2_3282 -1.8 -2.6 FIG005080: Possible exported protein compare
Pf6N2E2_3461 -1.8 -1.9 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5402 -1.8 -7.5 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_1717 -1.7 -8.7 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_4009 -1.7 -8.5 GGDEF domain protein compare
Pf6N2E2_3460 -1.7 -1.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2869 -1.7 -1.8 Peptide deformylase (EC 3.5.1.88) compare
Pf6N2E2_2320 -1.7 -3.3 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3477 -1.6 -2.3 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_1032 -1.6 -1.6 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_4710 -1.6 -2.7 hypothetical protein compare
Pf6N2E2_5404 -1.6 -6.1 ABC transporter for D-Alanine, permease component 1 (from data) conserved
Pf6N2E2_5001 -1.6 -1.7 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3264 -1.6 -2.3 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_2513 -1.5 -4.0 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2864 -1.5 -2.1 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4987 -1.5 -1.5 MaoC-like domain protein compare
Pf6N2E2_3885 -1.5 -2.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2707 -1.5 -4.4 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_5740 -1.5 -5.6 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_4918 -1.5 -2.4 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_5257 -1.5 -6.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_658 -1.4 -7.0 sensor histidine kinase compare
Pf6N2E2_2318 -1.4 -6.3 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2428 -1.4 -2.0 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_2413 -1.4 -2.2 FIG074102: hypothetical protein compare
Pf6N2E2_4049 -1.4 -6.3 Glycine cleavage system transcriptional activator compare
Pf6N2E2_3521 -1.4 -6.8 Sensor histidine kinase/response regulator compare
Pf6N2E2_5258 -1.4 -6.0 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4476 -1.4 -5.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_4416 -1.4 -2.2 Tyrosine recombinase XerC compare
Pf6N2E2_4372 -1.3 -3.6 FIG00460773: hypothetical protein compare
Pf6N2E2_2588 -1.3 -2.4 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4352 -1.3 -2.6 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4205 -1.3 -2.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2068 -1.2 -6.6 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_2510 -1.2 -2.8 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_1450 -1.2 -1.5 FIG00960438: hypothetical protein compare
Pf6N2E2_2790 -1.2 -2.2 Helix-turn-helix motif compare
Pf6N2E2_5571 -1.2 -2.2 hypothetical protein compare
Pf6N2E2_5337 -1.2 -3.7 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4399 -1.2 -5.7 GGDEF domain/EAL domain protein compare
Pf6N2E2_1886 -1.2 -1.9 hypothetical protein compare
Pf6N2E2_3532 -1.2 -5.2 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_5338 -1.2 -6.7 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5745 -1.2 -4.8 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2065 -1.2 -3.4 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_4612 -1.2 -2.9 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5741 -1.2 -3.8 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_70 -1.2 -1.9 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2311 -1.2 -5.9 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_5394 -1.1 -3.0 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_2605 -1.1 -3.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2855 -1.1 -3.1 DGPFAETKE compare
Pf6N2E2_5155 -1.1 -2.3 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_1694 -1.1 -1.4 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_1506 -1.1 -2.4 Putative alkanesulfonate metabolism utilization regulator compare
Pf6N2E2_1283 -1.1 -2.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5746 -1.1 -2.0 Cobalamin synthase compare
Pf6N2E2_55 -1.1 -2.1 Probable hydrolase compare
Pf6N2E2_3535 -1.1 -4.0 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_338 -1.1 -1.6 Transcriptional regulator, AraC family compare
Pf6N2E2_2827 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_5869 -1.1 -2.5 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_2309 -1.1 -2.0 hypothetical protein compare
Pf6N2E2_614 -1.1 -5.9 3-carboxymuconate cyclase compare
Pf6N2E2_3869 -1.1 -6.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2313 -1.1 -2.3 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_1089 -1.1 -2.5 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_5738 -1.1 -5.0 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_5499 -1.1 -0.9 hypothetical protein compare
Pf6N2E2_4601 -1.1 -2.0 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_4743 -1.0 -0.7 hypothetical protein compare
Pf6N2E2_5331 -1.0 -4.2 ATPase, AFG1 family compare
Pf6N2E2_687 -1.0 -1.6 4-oxalocrotonate tautomerase (EC 5.3.2.-) compare
Pf6N2E2_958 -1.0 -3.6 hypothetical protein compare
Pf6N2E2_5077 -1.0 -3.1 hypothetical protein compare
Pf6N2E2_2890 -1.0 -5.3 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_3786 -1.0 -2.2 Twin-arginine translocation protein TatC compare
Pf6N2E2_1136 -1.0 -1.7 Transcriptional regulator, TetR family compare
Pf6N2E2_2064 -1.0 -2.4 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_5339 -1.0 -4.1 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4417 -1.0 -3.1 Protein of unknown function DUF484 compare
Pf6N2E2_6001 -1.0 -5.6 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_2060 -1.0 -6.2 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_2340 -1.0 -2.6 Transcriptional regulator, GntR family compare
Pf6N2E2_81 -1.0 -2.2 hypothetical protein compare
Pf6N2E2_1340 -1.0 -2.4 major pilin protein fimA compare
Pf6N2E2_2527 -1.0 -3.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_1056 -1.0 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2893 -1.0 -4.5 hypothetical protein compare
Pf6N2E2_2310 -1.0 -5.3 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_5722 -1.0 -2.9 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_1424 -1.0 -1.7 transcriptional regulator, TetR family compare
Pf6N2E2_1336 -1.0 -3.1 AraC family transcription regulator compare
Pf6N2E2_234 -1.0 -2.8 FIG00454312: hypothetical protein compare
Pf6N2E2_2442 -1.0 -6.3 sensor histidine kinase/response regulator compare
Pf6N2E2_6164 -1.0 -1.0 tRNA-Val-TAC compare
Pf6N2E2_1676 -1.0 -1.2 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_605 -1.0 -1.9 FIG002465: BNR repeat protein compare
Pf6N2E2_5705 -0.9 -1.6 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_5843 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_4412 -0.9 -5.7 Ammonium transporter compare
Pf6N2E2_3864 -0.9 -2.7 hypothetical protein compare
Pf6N2E2_3346 -0.9 -2.9 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_1124 -0.9 -1.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5160 -0.9 -1.3 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3537 -0.9 -2.7 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_3062 -0.9 -2.4 Membrane-associated zinc metalloprotease compare


Specific Phenotypes

For 15 genes in this experiment

For nitrogen source L-Histidine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source L-Histidine across organisms