Experiment setAIT052 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cadmium chloride hemipentahydrate 0.000015625 M

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_2129 -5.9 -5.8 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_5014 -5.2 -2.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3661 -4.8 -5.7 hypothetical protein compare
Pf6N2E2_5527 -4.3 -3.0 Cold shock protein CspC compare
Pf6N2E2_4353 -4.2 -7.5 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5068 -3.9 -11.8 putative Cytochrome bd2, subunit I compare
Pf6N2E2_5069 -3.5 -5.9 putative Cytochrome bd2, subunit II compare
Pf6N2E2_3948 -3.4 -11.2 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3659 -3.4 -7.2 Protein fixF compare
Pf6N2E2_3908 -3.3 -8.7 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3461 -3.2 -3.0 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2181 -3.1 -2.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5342 -3.1 -4.6 21 kDa hemolysin precursor compare
Pf6N2E2_4352 -2.9 -4.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4803 -2.8 -2.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_1545 -2.8 -5.3 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_2218 -2.6 -5.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2827 -2.5 -2.0 hypothetical protein compare
Pf6N2E2_4454 -2.5 -7.2 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3658 -2.4 -8.4 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3303 -2.4 -5.1 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf6N2E2_5242 -2.4 -2.8 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4372 -2.3 -6.0 FIG00460773: hypothetical protein compare
Pf6N2E2_4187 -2.2 -5.3 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5560 -2.2 -3.7 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf6N2E2_4416 -2.2 -3.6 Tyrosine recombinase XerC compare
Pf6N2E2_2217 -2.2 -5.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5160 -2.1 -2.8 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_1056 -2.0 -1.3 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2189 -2.0 -6.3 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3947 -2.0 -3.0 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_622 -2.0 -6.3 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_1824 -1.9 -2.6 hypothetical protein compare
Pf6N2E2_3941 -1.9 -3.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_4162 -1.9 -3.9 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3617 -1.8 -4.9 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_2700 -1.8 -5.6 Cysteine synthase (EC 2.5.1.47) compare
Pf6N2E2_5536 -1.8 -2.6 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5316 -1.7 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5557 -1.7 -9.7 L-serine ammonia-lyase (EC 4.3.1.17) (from data) compare
Pf6N2E2_1509 -1.7 -4.1 FIG00450070: hypothetical protein compare
Pf6N2E2_5406 -1.7 -2.8 FIG00958224: hypothetical protein compare
Pf6N2E2_5155 -1.6 -3.3 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3611 -1.6 -1.5 HflC protein compare
Pf6N2E2_3191 -1.6 -5.0 Serine acetyltransferase (EC 2.3.1.30) compare
Pf6N2E2_3264 -1.6 -2.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4612 -1.5 -4.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5430 -1.5 -7.7 Transglycosylase, Slt family compare
Pf6N2E2_5640 -1.5 -2.5 FIG00955597: hypothetical protein compare
Pf6N2E2_5156 -1.5 -3.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3634 -1.5 -2.6 Transporter compare
Pf6N2E2_3847 -1.5 -4.1 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_170 -1.5 -2.8 lipoprotein, putative compare
Pf6N2E2_5006 -1.5 -6.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3260 -1.5 -5.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3074 -1.5 -1.6 FIG00960973: hypothetical protein compare
Pf6N2E2_3258 -1.4 -4.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1502 -1.4 -1.8 Two-component system regulatory protein compare
Pf6N2E2_3876 -1.4 -4.9 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_4415 -1.4 -2.6 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_5558 -1.3 -7.9 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) compare
Pf6N2E2_4362 -1.3 -3.4 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_6064 -1.3 -5.6 2-methylaconitate isomerase compare
Pf6N2E2_2674 -1.3 -1.6 FIG00953856: hypothetical protein compare
Pf6N2E2_3122 -1.3 -2.3 Chemotaxis signal transduction protein compare
Pf6N2E2_2261 -1.3 -5.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_2506 -1.3 -8.8 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_16 -1.3 -2.1 hypothetical protein compare
Pf6N2E2_1147 -1.3 -2.6 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_2574 -1.3 -1.4 Flagellar synthesis regulator FleN compare
Pf6N2E2_3460 -1.2 -1.3 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3607 -1.2 -5.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2384 -1.2 -3.9 CmpX compare
Pf6N2E2_2870 -1.2 -3.9 Ribonuclease BN (EC 3.1.-.-) compare
Pf6N2E2_2219 -1.2 -1.8 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_1691 -1.2 -2.9 hypothetical protein compare
Pf6N2E2_1635 -1.2 -4.5 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_1699 -1.1 -3.2 FIG00955832: hypothetical protein compare
Pf6N2E2_3834 -1.1 -5.3 Lipoprotein NlpD compare
Pf6N2E2_5727 -1.1 -4.2 FIG00955360: hypothetical protein compare
Pf6N2E2_1089 -1.1 -1.9 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_1625 -1.1 -3.1 Ferric reductase (1.6.99.14) compare
Pf6N2E2_2317 -1.1 -3.6 Putative analog of CcoH, COG3198 compare
Pf6N2E2_238 -1.1 -2.3 hypothetical protein compare
Pf6N2E2_4153 -1.1 -1.1 Sensory box histidine kinase compare
Pf6N2E2_4206 -1.0 -1.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_625 -1.0 -4.1 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_579 -1.0 -1.8 FIG00962753: hypothetical protein compare
Pf6N2E2_4678 -1.0 -0.9 hypothetical protein compare
Pf6N2E2_3257 -1.0 -3.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4585 -1.0 -7.2 Cell division protein FtsX compare
Pf6N2E2_5245 -1.0 -5.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4360 -1.0 -6.2 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_621 -1.0 -5.1 TPR domain protein in aerotolerance operon compare
Pf6N2E2_3782 -1.0 -3.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_1636 -1.0 -5.4 Ferrichrome-iron receptor compare
Pf6N2E2_4638 -1.0 -2.3 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5103 -1.0 -1.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_1652 -1.0 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_1606 -1.0 -4.7 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_5703 -1.0 -3.8 outer membrane protein H1 compare
Pf6N2E2_3252 -1.0 -4.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_6063 -1.0 -4.7 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_144 -1.0 -7.6 Uncharacterized protein YtfM precursor compare
Pf6N2E2_624 -0.9 -3.7 hypothetical protein PA3071 compare
Pf6N2E2_2320 -0.9 -1.9 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3062 -0.9 -3.0 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2188 -0.9 -2.5 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_2325 -0.9 -3.8 Recombination protein RecR compare
Pf6N2E2_2424 -0.9 -3.1 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_2340 -0.9 -2.9 Transcriptional regulator, GntR family compare
Pf6N2E2_1634 -0.9 -3.9 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_145 -0.9 -5.8 putative exported protein compare
Pf6N2E2_3839 -0.9 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_2311 -0.9 -5.1 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_4611 -0.9 -2.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_1694 -0.9 -1.3 FMN reductase (EC 1.5.1.29) compare
Pf6N2E2_2967 -0.9 -1.8 Cold shock protein CspA compare
Pf6N2E2_4205 -0.9 -2.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_623 -0.9 -1.3 FIG00954674: hypothetical protein compare
Pf6N2E2_2552 -0.9 -4.3 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_2278 -0.9 -7.1 Transcription-repair coupling factor compare
Pf6N2E2_2507 -0.9 -4.0 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_75 -0.9 -2.7 Colicin V production protein compare
Pf6N2E2_3696 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_2473 -0.9 -1.1 Major outer membrane lipoprotein I compare
Pf6N2E2_3786 -0.9 -2.5 Twin-arginine translocation protein TatC compare
Pf6N2E2_4751 -0.9 -3.0 response regulator compare
Pf6N2E2_3833 -0.8 -3.5 hypothetical protein compare
Pf6N2E2_2313 -0.8 -2.0 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_5188 -0.8 -2.7 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3627 -0.8 -4.7 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_2285 -0.8 -1.5 FIG00954079: hypothetical protein compare
Pf6N2E2_2508 -0.8 -3.2 hypothetical protein compare
Pf6N2E2_6062 -0.8 -4.6 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_2193 -0.8 -4.1 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) compare
Pf6N2E2_5677 -0.8 -1.2 Carbon storage regulator compare
Pf6N2E2_3351 -0.8 -2.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5841 -0.8 -1.0 GlcG protein compare
Pf6N2E2_3282 -0.8 -1.5 FIG005080: Possible exported protein compare
Pf6N2E2_3612 -0.8 -1.5 HflK protein compare
Pf6N2E2_1932 -0.8 -3.5 Transcriptional regulator, IclR family compare
Pf6N2E2_4084 -0.8 -4.4 Transcriptional regulator compare
Pf6N2E2_4584 -0.8 -1.2 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2675 -0.8 -0.9 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_6070 -0.8 -2.1 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf6N2E2_4618 -0.8 -2.8 Chemotaxis signal transduction protein compare
Pf6N2E2_3373 -0.8 -1.2 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_4092 -0.8 -2.7 FIG00954395: hypothetical protein compare
Pf6N2E2_1701 -0.8 -2.6 ABC transporter ATP-binding protein compare
Pf6N2E2_2194 -0.8 -4.6 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) compare
Pf6N2E2_4155 -0.7 -4.8 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_241 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_3039 -0.7 -2.3 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5291 -0.7 -6.3 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_2586 -0.7 -1.0 Hpt domain protein compare
Pf6N2E2_1391 -0.7 -1.5 DNA-binding response regulator, LuxR family compare
Pf6N2E2_2318 -0.7 -4.3 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5679 -0.7 -3.0 hypothetical protein compare
Pf6N2E2_3255 -0.7 -2.3 YrbA protein compare
Pf6N2E2_4908 -0.7 -3.7 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3534 -0.7 -2.2 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3610 -0.7 -2.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3261 -0.7 -2.7 hypothetical protein compare
Pf6N2E2_927 -0.7 -2.2 (AJ250023) putative polyketide synthase compare
Pf6N2E2_5876 -0.7 -2.4 Lipase (EC 3.1.1.3) compare
Pf6N2E2_3118 -0.7 -3.3 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf6N2E2_2753 -0.7 -1.8 HtrA protease/chaperone protein compare
Pf6N2E2_3885 -0.7 -1.7 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2527 -0.7 -2.9 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_40 -0.7 -3.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5705 -0.7 -1.5 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_4159 -0.7 -2.6 Cytochrome c4 compare
Pf6N2E2_3869 -0.7 -5.1 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3641 -0.7 -1.7 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Pf6N2E2_4438 -0.7 -2.2 hypothetical protein compare
Pf6N2E2_620 -0.7 -3.7 BatD compare
Pf6N2E2_3157 -0.7 -3.5 tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase compare
Pf6N2E2_5520 -0.7 -3.1 Sensory box histidine kinase compare
Pf6N2E2_3783 -0.7 -2.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_55 -0.7 -1.4 Probable hydrolase compare
Pf6N2E2_1673 -0.7 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_6001 -0.7 -3.9 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_4802 -0.7 -3.3 Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1) compare
Pf6N2E2_1860 -0.7 -1.7 Ferredoxin, 2Fe-2S compare
Pf6N2E2_2496 -0.7 -1.2 FIG00956575: hypothetical protein compare
Pf6N2E2_6077 -0.7 -3.2 Cysteine desulfurase (EC 2.8.1.7) compare
Pf6N2E2_4086 -0.7 -5.5 sodium/alanine transporter compare
Pf6N2E2_746 -0.7 -1.3 FIG00958097: hypothetical protein compare
Pf6N2E2_1464 -0.6 -2.3 hypothetical protein compare
Pf6N2E2_3842 -0.6 -1.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2682 -0.6 -1.7 Transcriptional regulator, LysR family compare
Pf6N2E2_1696 -0.6 -2.0 Alkanesulfonates-binding protein compare
Pf6N2E2_2533 -0.6 -4.5 Rhodanese domain protein UPF0176 compare
Pf6N2E2_3982 -0.6 -1.8 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf6N2E2_447 -0.6 -3.1 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) compare
Pf6N2E2_2588 -0.6 -2.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_138 -0.6 -2.7 Alpha/beta hydrolase fold (EC 3.8.1.5) compare
Pf6N2E2_74 -0.6 -1.0 DedD protein compare
Pf6N2E2_5339 -0.6 -3.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare


Specific Phenotypes

For 9 genes in this experiment

For stress Cadmium chloride hemipentahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cadmium chloride hemipentahydrate across organisms