Experiment set9S186 for Methanococcus maripaludis JJ

Compare to:

Formate 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMJJ_RS02040 -5.4 -3.5 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS03840 -5.3 -3.7 DHH family phosphoesterase compare
MMJJ_RS01360 -5.1 -3.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS03620 -4.8 -8.7 DUF2097 domain-containing protein compare
MMJJ_RS08850 -4.4 -5.0 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS06625 -4.3 -3.2 pyruvate synthase subunit PorB compare
MMJJ_RS08625 -4.3 -9.1 magnesium/cobalt transporter CorA compare
MMJJ_RS05445 -4.3 -3.8 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS04200 -4.3 -8.4 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS03190 -4.2 -5.0 phosphopyruvate hydratase compare
MMJJ_RS05490 -4.1 -4.0 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS03865 -3.8 -3.7 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS00355 -3.7 -5.1 ribonuclease P protein component 4 compare
MMJJ_RS07785 -3.7 -5.0 fumarate reductase subunit A compare
MMJJ_RS01870 -3.6 -3.5 methanogenesis marker 15 protein compare
MMJJ_RS03150 -3.6 -9.0 2-phospho-L-lactate transferase compare
MMJJ_RS04800 -3.5 -9.1 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS03820 -3.5 -6.0 hydrogenase formation protein HypD compare
MMJJ_RS03895 -3.5 -5.1 hydrogenase expression/formation protein HypE compare
MMJJ_RS02045 -3.4 -3.5 molybdenum cofactor guanylyltransferase compare
MMJJ_RS03500 -3.4 -16.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMJJ_RS08320 -3.4 -4.0 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS06840 -3.4 -5.2 nickel-dependent hydrogenase large subunit compare
MMJJ_RS09130 -3.4 -2.8 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS06860 -3.4 -7.1 hypothetical protein compare
MMJJ_RS00125 -3.4 -4.2 KEOPS complex subunit Cgi121 compare
MMJJ_RS08535 -3.3 -5.1 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS05620 -3.3 -7.0 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein compare
MMJJ_RS07945 -3.3 -4.2 4Fe-4S binding protein compare
MMJJ_RS04655 -3.3 -5.9 FAD-dependent oxidoreductase compare
MMJJ_RS06855 -3.3 -2.7 DUF2104 domain-containing protein compare
MMJJ_RS05770 -3.3 -3.6 flagellar protein D compare
MMJJ_RS06700 -3.3 -7.2 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS02920 -3.3 -4.2 30S ribosomal protein S27ae compare
MMJJ_RS03110 -3.2 -5.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS01755 -3.2 -4.3 ferrous iron transport protein B compare
MMJJ_RS00275 -3.2 -4.1 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS09175 -3.2 -2.6 anthranilate synthase component I compare
MMJJ_RS01810 -3.2 -3.1 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS03760 -3.1 -4.9 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS00475 -3.1 -2.5 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS04685 -3.1 -10.2 carbamoyltransferase HypF compare
MMJJ_RS04155 -3.1 -9.1 hypothetical protein compare
MMJJ_RS06600 -3.0 -3.5 DUF555 domain-containing protein compare
MMJJ_RS03200 -3.0 -4.0 uroporphyrinogen-III synthase compare
MMJJ_RS07725 -3.0 -6.3 DNA primase DnaG compare
MMJJ_RS03615 -3.0 -4.8 cobalt-precorrin-8 methylmutase compare
MMJJ_RS03785 -2.9 -4.4 hypothetical protein compare
MMJJ_RS07655 -2.9 -14.8 hypothetical protein compare
MMJJ_RS00580 -2.9 -2.9 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS05260 -2.9 -7.7 ATP-grasp domain-containing protein compare
MMJJ_RS06490 -2.8 -4.1 methanogenesis marker 2 protein compare
MMJJ_RS05575 -2.8 -4.6 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS00600 -2.8 -4.6 hydroxymethylbilane synthase compare
MMJJ_RS06510 -2.8 -4.0 LL-diaminopimelate aminotransferase compare
MMJJ_RS07665 -2.8 -20.7 formate dehydrogenase subunit alpha compare
MMJJ_RS03160 -2.8 -11.9 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS05155 -2.8 -7.1 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS05765 -2.7 -2.0 flagellar protein E compare
MMJJ_RS00215 -2.7 -3.0 CCA tRNA nucleotidyltransferase compare
MMJJ_RS07670 -2.7 -18.8 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS02200 -2.7 -11.0 chorismate pyruvate-lyase family protein compare
MMJJ_RS02275 -2.7 -6.0 nucleotidyltransferase domain-containing protein compare
MMJJ_RS00550 -2.7 -9.3 AIR synthase-related protein compare
MMJJ_RS05930 -2.6 -2.8 cell division protein SepF compare
MMJJ_RS01765 -2.6 -13.7 winged helix-turn-helix domain-containing protein compare
MMJJ_RS07000 -2.6 -2.3 TrkH family potassium uptake protein compare
MMJJ_RS06725 -2.6 -15.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS07415 -2.6 -3.6 polyprenyl diphosphate synthase compare
MMJJ_RS01350 -2.6 -7.9 sodium:proton antiporter compare
MMJJ_RS09190 -2.6 -3.3 tryptophan synthase subunit beta compare
MMJJ_RS03140 -2.6 -11.8 tRNA-dihydrouridine synthase compare
MMJJ_RS02935 -2.6 -5.6 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS07245 -2.6 -5.7 amidohydrolase family protein compare
MMJJ_RS05360 -2.6 -7.4 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS08055 -2.6 -7.2 methanogenesis marker 14 protein compare
MMJJ_RS06940 -2.6 -12.3 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS06485 -2.5 -4.5 phosphoglycerate kinase compare
MMJJ_RS05950 -2.5 -4.7 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
MMJJ_RS06255 -2.5 -7.1 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS06930 -2.5 -3.6 type II methionyl aminopeptidase compare
MMJJ_RS04975 -2.5 -3.7 glycosyltransferase family 4 protein compare
MMJJ_RS03055 -2.5 -3.4 hypothetical protein compare
MMJJ_RS06875 -2.5 -4.0 hypothetical protein compare
MMJJ_RS05935 -2.4 -3.2 Era-like GTP-binding protein compare
MMJJ_RS08080 -2.4 -10.7 TIGR00300 family protein compare
MMJJ_RS04675 -2.4 -7.2 thiamine pyrophosphate-binding protein compare
MMJJ_RS07345 -2.4 -7.2 homocysteine biosynthesis protein compare
MMJJ_RS01475 -2.4 -3.0 signal recognition particle-docking protein FtsY compare
MMJJ_RS09375 -2.4 -3.4 hypothetical protein compare
MMJJ_RS07950 -2.4 -4.4 4Fe-4S binding protein compare
MMJJ_RS07410 -2.4 -4.9 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS00270 -2.3 -3.8 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS04730 -2.3 -4.1 tyrosine decarboxylase MfnA compare
MMJJ_RS06180 -2.3 -4.4 tryptophan--tRNA ligase compare
MMJJ_RS03580 -2.3 -4.4 TIGR00303 family protein compare
MMJJ_RS04980 -2.3 -4.5 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS06240 -2.3 -4.1 dihydropteroate synthase-like protein compare
MMJJ_RS07350 -2.3 -2.8 4Fe-4S binding protein compare
MMJJ_RS04995 -2.3 -7.5 Tfx family DNA-binding protein compare
MMJJ_RS04700 -2.3 -6.6 deoxyhypusine synthase compare
MMJJ_RS05415 -2.3 -3.7 hypothetical protein compare
MMJJ_RS00360 -2.3 -3.0 adenosylhomocysteinase compare
MMJJ_RS01935 -2.3 -5.0 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS01880 -2.3 -4.0 RlmE family RNA methyltransferase compare
MMJJ_RS06905 -2.3 -2.4 hypothetical protein compare
MMJJ_RS08660 -2.2 -4.1 acetylornithine transaminase compare
MMJJ_RS05650 -2.2 -4.0 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS02090 -2.2 -6.7 tyramine--L-glutamate ligase compare
MMJJ_RS05610 -2.2 -5.9 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS04595 -2.2 -6.2 hypothetical protein compare
MMJJ_RS07470 -2.2 -2.3 50S ribosome-binding GTPase compare
MMJJ_RS05995 -2.2 -2.6 ATP-binding cassette domain-containing protein compare
MMJJ_RS04970 -2.2 -1.8 DUF655 domain-containing protein compare
MMJJ_RS01355 -2.2 -4.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS08095 -2.2 -5.8 cobyric acid synthase CobQ compare
MMJJ_RS03125 -2.2 -5.2 GMC oxidoreductase compare
MMJJ_RS08325 -2.2 -3.5 glycosyltransferase family 2 protein compare
MMJJ_RS00560 -2.1 -5.5 homoisocitrate dehydrogenase compare
MMJJ_RS08020 -2.1 -11.0 nucleotidyltransferase domain-containing protein compare
MMJJ_RS05225 -2.1 -2.4 Gar1/Naf1 family protein compare
MMJJ_RS08250 -2.1 -7.3 hydrogenase maturation peptidase HycI compare
MMJJ_RS06785 -2.1 -8.4 RNA ligase partner protein compare
MMJJ_RS01345 -2.1 -4.4 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS01600 -2.1 -3.4 radical SAM protein compare
MMJJ_RS08005 -2.1 -16.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS08840 -2.1 -5.3 calcium/sodium antiporter compare
MMJJ_RS08620 -2.1 -3.8 DUF373 family protein compare
MMJJ_RS08330 -2.1 -3.5 SufD family Fe-S cluster assembly protein compare
MMJJ_RS01690 -2.1 -4.6 methanogenesis marker 12 protein compare
MMJJ_RS00205 -2.1 -6.9 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS02055 -2.1 -12.4 GTP 3',8-cyclase MoaA compare
MMJJ_RS06390 -2.1 -3.4 NADPH-dependent F420 reductase compare
MMJJ_RS06695 -2.1 -3.2 amidohydrolase compare
MMJJ_RS04505 -2.1 -6.3 CDC48 family AAA ATPase compare
MMJJ_RS04520 -2.0 -6.2 coenzyme F430 synthase compare
MMJJ_RS07995 -2.0 -8.6 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS04110 -2.0 -5.8 hypothetical protein compare
MMJJ_RS07805 -2.0 -10.2 ferredoxin family protein compare
MMJJ_RS05655 -2.0 -6.6 HisA/HisF family protein compare
MMJJ_RS07660 -2.0 -10.0 carbonic anhydrase compare
MMJJ_RS08855 -2.0 -5.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS05190 -2.0 -10.8 gamma carbonic anhydrase family protein compare
MMJJ_RS03670 -2.0 -4.8 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS07360 -2.0 -2.3 TIGR00269 family protein compare
MMJJ_RS08155 -2.0 -4.6 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS04485 -2.0 -9.5 riboflavin synthase compare
MMJJ_RS05540 -2.0 -14.7 LysR family transcriptional regulator compare
MMJJ_RS04790 -2.0 -4.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS06010 -2.0 -8.2 hypothetical protein compare
MMJJ_RS03875 -2.0 -4.7 CBS domain-containing protein compare
MMJJ_RS08795 -1.9 -3.3 phosphoglucosamine mutase compare
MMJJ_RS07810 -1.9 -12.2 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMJJ_RS03005 -1.9 -4.8 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS06015 -1.9 -10.5 Na(+)/H(+) antiporter subunit B compare
MMJJ_RS06865 -1.9 -2.3 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS03095 -1.9 -3.4 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS07815 -1.9 -13.9 2-oxoacid:acceptor oxidoreductase family protein compare
MMJJ_RS06155 -1.9 -5.5 phosphatidylglycerophosphatase A compare
MMJJ_RS05330 -1.9 -3.0 DNA polymerase II large subunit compare
MMJJ_RS01875 -1.9 -5.0 global nitrogen regulator NrpR compare
MMJJ_RS05065 -1.9 -4.7 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS00570 -1.9 -1.7 ribonuclease P compare
MMJJ_RS01415 -1.9 -2.9 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS06705 -1.8 -5.4 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS06005 -1.8 -8.7 energy conserving hydrogenase EhbF compare
MMJJ_RS05710 -1.8 -4.3 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS08340 -1.8 -5.0 archaeoflavoprotein AfpA compare
MMJJ_RS07155 -1.8 -8.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS07190 -1.8 -4.3 RtcB family protein compare
MMJJ_RS01750 -1.8 -4.1 ferrous iron transport protein A compare
MMJJ_RS06050 -1.8 -10.1 molybdopterin molybdotransferase MoeA compare
MMJJ_RS06225 -1.8 -2.3 adenosylmethionine decarboxylase compare
MMJJ_RS05070 -1.8 -3.1 DNA primase catalytic subunit PriS compare
MMJJ_RS09055 -1.8 -8.1 NFACT family protein compare
MMJJ_RS07015 -1.8 -1.8 PFL family protein compare
MMJJ_RS08150 -1.8 -13.9 M24 family metallopeptidase compare
MMJJ_RS03815 -1.8 -2.6 nascent polypeptide-associated complex protein compare
MMJJ_RS06915 -1.8 -9.7 helix-turn-helix domain-containing protein compare
MMJJ_RS05380 -1.8 -1.8 hypothetical protein compare
MMJJ_RS04145 -1.8 -8.6 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS07705 -1.7 -3.3 GTP-binding protein EngB compare
MMJJ_RS06220 -1.7 -5.1 polyamine aminopropyltransferase compare
MMJJ_RS03295 -1.7 -10.6 PHP domain-containing protein compare
MMJJ_RS05780 -1.7 -4.5 flagellin compare
MMJJ_RS06040 -1.7 -3.9 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS06000 -1.7 -5.9 cation:proton antiporter subunit C compare
MMJJ_RS08000 -1.7 -9.8 HesA/MoeB/ThiF family protein compare
MMJJ_RS07430 -1.7 -4.3 ribonuclease VapC compare
MMJJ_RS08480 -1.7 -8.8 hydroxyethylthiazole kinase compare
MMJJ_RS04985 -1.7 -3.1 glutamyl-tRNA reductase compare
MMJJ_RS00370 -1.7 -2.0 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS03765 -1.7 -6.7 hypothetical protein compare
MMJJ_RS05370 -1.6 -8.1 LysR family transcriptional regulator compare
MMJJ_RS05535 -1.6 -10.0 hypothetical protein compare
MMJJ_RS08405 -1.6 -10.6 nickel-dependent hydrogenase large subunit compare
MMJJ_RS00265 -1.6 -8.5 TIGR02253 family HAD-type hydrolase compare
MMJJ_RS03170 -1.6 -6.3 DUF5612 domain-containing protein compare
MMJJ_RS06250 -1.6 -2.4 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS08585 -1.6 -9.3 M42 family metallopeptidase compare


Specific Phenotypes

For 2 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis JJ

For stress Sodium hypophosphite across organisms