Experiment set9S185 for Methanococcus maripaludis JJ

Compare to:

Formate 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMJJ_RS04975 -5.4 -3.8 glycosyltransferase family 4 protein compare
MMJJ_RS03620 -4.9 -9.3 DUF2097 domain-containing protein compare
MMJJ_RS01750 -4.8 -4.5 ferrous iron transport protein A compare
MMJJ_RS06625 -4.6 -3.8 pyruvate synthase subunit PorB compare
MMJJ_RS07950 -4.5 -5.9 4Fe-4S binding protein compare
MMJJ_RS05930 -4.5 -4.1 cell division protein SepF compare
MMJJ_RS05070 -4.2 -4.1 DNA primase catalytic subunit PriS compare
MMJJ_RS04200 -4.2 -9.9 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS08625 -4.1 -9.5 magnesium/cobalt transporter CorA compare
MMJJ_RS03895 -4.1 -5.9 hydrogenase expression/formation protein HypE compare
MMJJ_RS05620 -4.1 -6.7 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein compare
MMJJ_RS06180 -4.0 -4.8 tryptophan--tRNA ligase compare
MMJJ_RS02040 -4.0 -2.3 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS05720 -4.0 -4.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS04970 -4.0 -2.9 DUF655 domain-containing protein compare
MMJJ_RS01360 -4.0 -3.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS03055 -3.9 -6.5 hypothetical protein compare
MMJJ_RS03865 -3.9 -3.5 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS04155 -3.8 -9.2 hypothetical protein compare
MMJJ_RS00275 -3.7 -4.4 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS00450 -3.6 -3.6 DUF126 domain-containing protein compare
MMJJ_RS03200 -3.6 -4.3 uroporphyrinogen-III synthase compare
MMJJ_RS04800 -3.6 -8.9 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS02045 -3.6 -4.8 molybdenum cofactor guanylyltransferase compare
MMJJ_RS06750 -3.5 -3.9 homoaconitase large subunit compare
MMJJ_RS01935 -3.5 -7.3 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS03840 -3.5 -6.2 DHH family phosphoesterase compare
MMJJ_RS06700 -3.4 -9.1 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS05490 -3.4 -4.7 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS06875 -3.4 -4.4 hypothetical protein compare
MMJJ_RS05155 -3.4 -8.0 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS02920 -3.4 -2.9 30S ribosomal protein S27ae compare
MMJJ_RS05650 -3.3 -3.6 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS07415 -3.3 -4.2 polyprenyl diphosphate synthase compare
MMJJ_RS06490 -3.3 -4.9 methanogenesis marker 2 protein compare
MMJJ_RS00580 -3.3 -3.4 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS03160 -3.3 -12.6 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS05330 -3.3 -3.8 DNA polymerase II large subunit compare
MMJJ_RS03500 -3.2 -15.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMJJ_RS07350 -3.2 -4.9 4Fe-4S binding protein compare
MMJJ_RS04685 -3.2 -11.8 carbamoyltransferase HypF compare
MMJJ_RS08055 -3.2 -7.8 methanogenesis marker 14 protein compare
MMJJ_RS05610 -3.1 -6.4 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS06390 -3.1 -2.6 NADPH-dependent F420 reductase compare
MMJJ_RS03270 -3.1 -2.9 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS03820 -3.0 -6.4 hydrogenase formation protein HypD compare
MMJJ_RS06860 -3.0 -6.2 hypothetical protein compare
MMJJ_RS08320 -3.0 -2.7 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS08850 -3.0 -3.5 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS06510 -3.0 -3.1 LL-diaminopimelate aminotransferase compare
MMJJ_RS09190 -2.9 -3.0 tryptophan synthase subunit beta compare
MMJJ_RS01345 -2.9 -4.2 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS06940 -2.9 -12.6 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS03760 -2.9 -6.0 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS03190 -2.9 -4.4 phosphopyruvate hydratase compare
MMJJ_RS01765 -2.9 -12.6 winged helix-turn-helix domain-containing protein compare
MMJJ_RS03095 -2.9 -4.0 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS08660 -2.9 -5.1 acetylornithine transaminase compare
MMJJ_RS00355 -2.8 -4.5 ribonuclease P protein component 4 compare
MMJJ_RS05445 -2.8 -3.6 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS07430 -2.8 -5.5 ribonuclease VapC compare
MMJJ_RS04675 -2.8 -6.6 thiamine pyrophosphate-binding protein compare
MMJJ_RS01355 -2.8 -4.9 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS07655 -2.8 -16.4 hypothetical protein compare
MMJJ_RS03150 -2.8 -7.8 2-phospho-L-lactate transferase compare
MMJJ_RS09175 -2.8 -1.5 anthranilate synthase component I compare
MMJJ_RS07665 -2.7 -22.0 formate dehydrogenase subunit alpha compare
MMJJ_RS06805 -2.7 -3.5 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS06240 -2.7 -3.7 dihydropteroate synthase-like protein compare
MMJJ_RS07360 -2.7 -2.1 TIGR00269 family protein compare
MMJJ_RS03125 -2.6 -7.3 GMC oxidoreductase compare
MMJJ_RS07670 -2.6 -20.0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS03580 -2.6 -4.1 TIGR00303 family protein compare
MMJJ_RS08795 -2.6 -3.8 phosphoglucosamine mutase compare
MMJJ_RS05415 -2.6 -3.9 hypothetical protein compare
MMJJ_RS07345 -2.6 -6.2 homocysteine biosynthesis protein compare
MMJJ_RS00125 -2.5 -4.2 KEOPS complex subunit Cgi121 compare
MMJJ_RS06255 -2.5 -6.6 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS03670 -2.5 -5.7 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS00370 -2.5 -3.2 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS01810 -2.5 -3.0 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS05260 -2.5 -6.5 ATP-grasp domain-containing protein compare
MMJJ_RS04655 -2.5 -6.0 FAD-dependent oxidoreductase compare
MMJJ_RS06725 -2.5 -14.3 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS08620 -2.5 -3.2 DUF373 family protein compare
MMJJ_RS07470 -2.5 -3.0 50S ribosome-binding GTPase compare
MMJJ_RS00205 -2.4 -7.3 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS07725 -2.4 -7.3 DNA primase DnaG compare
MMJJ_RS08840 -2.4 -5.9 calcium/sodium antiporter compare
MMJJ_RS00550 -2.4 -9.0 AIR synthase-related protein compare
MMJJ_RS03110 -2.4 -4.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS06840 -2.4 -5.1 nickel-dependent hydrogenase large subunit compare
MMJJ_RS03140 -2.4 -14.1 tRNA-dihydrouridine synthase compare
MMJJ_RS06485 -2.4 -4.0 phosphoglycerate kinase compare
MMJJ_RS05190 -2.4 -13.2 gamma carbonic anhydrase family protein compare
MMJJ_RS01755 -2.4 -3.9 ferrous iron transport protein B compare
MMJJ_RS06930 -2.4 -3.6 type II methionyl aminopeptidase compare
MMJJ_RS05360 -2.3 -8.0 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS04790 -2.3 -3.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS07410 -2.3 -5.7 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS05575 -2.3 -3.5 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS00270 -2.3 -4.2 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS08080 -2.3 -9.3 TIGR00300 family protein compare
MMJJ_RS08095 -2.3 -4.9 cobyric acid synthase CobQ compare
MMJJ_RS08250 -2.3 -7.9 hydrogenase maturation peptidase HycI compare
MMJJ_RS01600 -2.3 -2.9 radical SAM protein compare
MMJJ_RS06155 -2.3 -6.3 phosphatidylglycerophosphatase A compare
MMJJ_RS01350 -2.2 -5.8 sodium:proton antiporter compare
MMJJ_RS04110 -2.2 -6.8 hypothetical protein compare
MMJJ_RS08535 -2.2 -5.3 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS07785 -2.2 -3.3 fumarate reductase subunit A compare
MMJJ_RS06225 -2.2 -2.8 adenosylmethionine decarboxylase compare
MMJJ_RS07705 -2.2 -3.3 GTP-binding protein EngB compare
MMJJ_RS06855 -2.2 -2.4 DUF2104 domain-containing protein compare
MMJJ_RS04145 -2.2 -10.2 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS06170 -2.2 -9.9 hypothetical protein compare
MMJJ_RS02090 -2.2 -5.8 tyramine--L-glutamate ligase compare
MMJJ_RS06695 -2.2 -4.1 amidohydrolase compare
MMJJ_RS05770 -2.2 -3.8 flagellar protein D compare
MMJJ_RS06040 -2.2 -5.3 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS06785 -2.2 -8.0 RNA ligase partner protein compare
MMJJ_RS08005 -2.1 -16.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS00600 -2.1 -3.6 hydroxymethylbilane synthase compare
MMJJ_RS07720 -2.1 -2.5 UPF0058 family protein compare
MMJJ_RS04485 -2.1 -10.4 riboflavin synthase compare
MMJJ_RS02935 -2.1 -4.0 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS06760 -2.1 -5.9 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS08855 -2.1 -4.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS04700 -2.1 -6.5 deoxyhypusine synthase compare
MMJJ_RS04995 -2.1 -5.8 Tfx family DNA-binding protein compare
MMJJ_RS01200 -2.0 -3.2 PRC-barrel domain-containing protein compare
MMJJ_RS05950 -2.0 -4.5 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
MMJJ_RS01870 -2.0 -2.6 methanogenesis marker 15 protein compare
MMJJ_RS03615 -2.0 -3.4 cobalt-precorrin-8 methylmutase compare
MMJJ_RS02275 -2.0 -4.1 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06910 -2.0 -4.4 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS00265 -2.0 -9.5 TIGR02253 family HAD-type hydrolase compare
MMJJ_RS06000 -2.0 -7.1 cation:proton antiporter subunit C compare
MMJJ_RS07945 -2.0 -3.5 4Fe-4S binding protein compare
MMJJ_RS05380 -2.0 -2.3 hypothetical protein compare
MMJJ_RS06865 -2.0 -2.7 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS06175 -2.0 -3.7 DUF1743 domain-containing protein compare
MMJJ_RS04730 -2.0 -4.0 tyrosine decarboxylase MfnA compare
MMJJ_RS05225 -2.0 -2.2 Gar1/Naf1 family protein compare
MMJJ_RS02055 -2.0 -14.2 GTP 3',8-cyclase MoaA compare
MMJJ_RS07810 -2.0 -15.5 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMJJ_RS02200 -2.0 -8.2 chorismate pyruvate-lyase family protein compare
MMJJ_RS07995 -1.9 -8.5 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS06705 -1.9 -4.5 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS08480 -1.9 -9.9 hydroxyethylthiazole kinase compare
MMJJ_RS05540 -1.9 -14.9 LysR family transcriptional regulator compare
MMJJ_RS07190 -1.9 -5.0 RtcB family protein compare
MMJJ_RS09375 -1.9 -2.6 hypothetical protein compare
MMJJ_RS08020 -1.9 -9.8 nucleotidyltransferase domain-containing protein compare
MMJJ_RS07815 -1.9 -13.9 2-oxoacid:acceptor oxidoreductase family protein compare
MMJJ_RS08000 -1.9 -11.3 HesA/MoeB/ThiF family protein compare
MMJJ_RS05655 -1.9 -6.1 HisA/HisF family protein compare
MMJJ_RS01415 -1.9 -3.0 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS00475 -1.9 -2.9 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS06915 -1.8 -10.1 helix-turn-helix domain-containing protein compare
MMJJ_RS06110 -1.8 -3.0 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS04505 -1.8 -6.8 CDC48 family AAA ATPase compare
MMJJ_RS08155 -1.8 -5.0 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS04520 -1.8 -4.6 coenzyme F430 synthase compare
MMJJ_RS05065 -1.8 -5.7 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS06010 -1.8 -6.8 hypothetical protein compare
MMJJ_RS08150 -1.8 -11.8 M24 family metallopeptidase compare
MMJJ_RS05710 -1.8 -3.8 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS08585 -1.8 -10.6 M42 family metallopeptidase compare
MMJJ_RS03295 -1.7 -11.9 PHP domain-containing protein compare
MMJJ_RS08340 -1.7 -4.3 archaeoflavoprotein AfpA compare
MMJJ_RS00415 -1.7 -9.1 DedA family protein compare
MMJJ_RS09055 -1.7 -9.3 NFACT family protein compare
MMJJ_RS05535 -1.7 -10.4 hypothetical protein compare
MMJJ_RS09130 -1.7 -2.7 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS04670 -1.7 -4.1 DUF2117 domain-containing protein compare
MMJJ_RS00570 -1.7 -2.8 ribonuclease P compare
MMJJ_RS05295 -1.7 -9.6 cobyrinic acid a,c-diamide synthase compare
MMJJ_RS04050 -1.7 -1.8 dihydroneopterin aldolase family protein compare
MMJJ_RS07155 -1.7 -8.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS03765 -1.7 -8.5 hypothetical protein compare
MMJJ_RS05810 -1.7 -6.2 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS05590 -1.7 -2.3 homoserine dehydrogenase compare
MMJJ_RS05370 -1.7 -9.2 LysR family transcriptional regulator compare
MMJJ_RS06185 -1.7 -4.1 cobalamin biosynthesis protein compare
MMJJ_RS08230 -1.7 -3.9 ribose-5-phosphate isomerase RpiA compare
MMJJ_RS07660 -1.7 -10.6 carbonic anhydrase compare
MMJJ_RS00560 -1.7 -5.1 homoisocitrate dehydrogenase compare
MMJJ_RS06035 -1.7 -10.2 NADH-quinone oxidoreductase subunit B family protein compare
MMJJ_RS06015 -1.7 -10.2 Na(+)/H(+) antiporter subunit B compare
MMJJ_RS08820 -1.7 -9.9 pyridoxal phosphate-dependent aminotransferase compare
MMJJ_RS04980 -1.7 -3.8 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS05780 -1.7 -2.7 flagellin compare
MMJJ_RS03845 -1.7 -3.8 translation initiation factor IF-2 compare
MMJJ_RS07805 -1.6 -8.4 ferredoxin family protein compare
MMJJ_RS06020 -1.6 -7.8 hypothetical protein compare
MMJJ_RS06905 -1.6 -1.6 hypothetical protein compare
MMJJ_RS01875 -1.6 -4.9 global nitrogen regulator NrpR compare
MMJJ_RS03965 -1.6 -3.5 DNA-directed RNA polymerase subunit L compare
MMJJ_RS02205 -1.6 -10.0 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis JJ

For stress Sodium hypophosphite across organisms