Experiment set9S184 for Methanococcus maripaludis JJ

Compare to:

Formate 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMJJ_RS06855 -5.9 -3.7 DUF2104 domain-containing protein compare
MMJJ_RS04200 -5.5 -9.9 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS04975 -5.4 -3.7 glycosyltransferase family 4 protein compare
MMJJ_RS03895 -5.3 -6.3 hydrogenase expression/formation protein HypE compare
MMJJ_RS05930 -5.3 -3.6 cell division protein SepF compare
MMJJ_RS03840 -5.0 -4.8 DHH family phosphoesterase compare
MMJJ_RS00275 -5.0 -4.2 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS08850 -4.9 -4.7 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS07720 -4.8 -3.4 UPF0058 family protein compare
MMJJ_RS02040 -4.7 -3.4 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS03620 -4.7 -8.4 DUF2097 domain-containing protein compare
MMJJ_RS08625 -4.7 -7.8 magnesium/cobalt transporter CorA compare
MMJJ_RS06175 -4.6 -4.4 DUF1743 domain-containing protein compare
MMJJ_RS00210 -4.5 -4.3 DUF530 family protein compare
MMJJ_RS05620 -4.4 -6.0 CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein compare
MMJJ_RS01360 -4.4 -4.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS07950 -4.2 -4.6 4Fe-4S binding protein compare
MMJJ_RS01935 -4.2 -6.2 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS06180 -4.2 -4.1 tryptophan--tRNA ligase compare
MMJJ_RS04155 -4.1 -9.1 hypothetical protein compare
MMJJ_RS06490 -4.0 -4.1 methanogenesis marker 2 protein compare
MMJJ_RS09175 -4.0 -2.0 anthranilate synthase component I compare
MMJJ_RS06510 -4.0 -4.2 LL-diaminopimelate aminotransferase compare
MMJJ_RS05155 -4.0 -8.0 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS06390 -4.0 -3.1 NADPH-dependent F420 reductase compare
MMJJ_RS06625 -4.0 -3.9 pyruvate synthase subunit PorB compare
MMJJ_RS06700 -4.0 -7.7 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS06875 -3.9 -3.3 hypothetical protein compare
MMJJ_RS03820 -3.9 -6.4 hydrogenase formation protein HypD compare
MMJJ_RS05260 -3.9 -7.1 ATP-grasp domain-containing protein compare
MMJJ_RS03190 -3.9 -5.2 phosphopyruvate hydratase compare
MMJJ_RS03500 -3.8 -14.6 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMJJ_RS08320 -3.7 -4.5 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS05610 -3.7 -6.2 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS05490 -3.7 -4.4 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS01355 -3.6 -5.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS01870 -3.6 -3.5 methanogenesis marker 15 protein compare
MMJJ_RS07415 -3.6 -4.9 polyprenyl diphosphate synthase compare
MMJJ_RS07785 -3.6 -4.2 fumarate reductase subunit A compare
MMJJ_RS03110 -3.6 -5.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS00270 -3.6 -5.1 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS04685 -3.6 -10.6 carbamoyltransferase HypF compare
MMJJ_RS02045 -3.5 -4.3 molybdenum cofactor guanylyltransferase compare
MMJJ_RS07725 -3.5 -7.6 DNA primase DnaG compare
MMJJ_RS06840 -3.5 -5.3 nickel-dependent hydrogenase large subunit compare
MMJJ_RS03150 -3.5 -8.3 2-phospho-L-lactate transferase compare
MMJJ_RS05415 -3.4 -3.7 hypothetical protein compare
MMJJ_RS07655 -3.4 -15.9 hypothetical protein compare
MMJJ_RS09375 -3.4 -2.8 hypothetical protein compare
MMJJ_RS07665 -3.4 -22.7 formate dehydrogenase subunit alpha compare
MMJJ_RS05950 -3.4 -5.6 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
MMJJ_RS08095 -3.4 -6.0 cobyric acid synthase CobQ compare
MMJJ_RS05650 -3.3 -4.7 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS00560 -3.3 -5.5 homoisocitrate dehydrogenase compare
MMJJ_RS05575 -3.3 -5.0 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS02090 -3.3 -8.0 tyramine--L-glutamate ligase compare
MMJJ_RS05330 -3.3 -3.9 DNA polymerase II large subunit compare
MMJJ_RS02920 -3.3 -4.0 30S ribosomal protein S27ae compare
MMJJ_RS08055 -3.3 -8.1 methanogenesis marker 14 protein compare
MMJJ_RS05720 -3.2 -3.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS06010 -3.2 -6.8 hypothetical protein compare
MMJJ_RS00475 -3.2 -4.1 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS03875 -3.2 -6.1 CBS domain-containing protein compare
MMJJ_RS06930 -3.2 -3.1 type II methionyl aminopeptidase compare
MMJJ_RS01350 -3.2 -7.1 sodium:proton antiporter compare
MMJJ_RS07190 -3.2 -5.6 RtcB family protein compare
MMJJ_RS04800 -3.2 -8.6 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS06725 -3.1 -13.3 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS07245 -3.1 -6.4 amidohydrolase family protein compare
MMJJ_RS07670 -3.1 -19.4 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS04655 -3.1 -6.6 FAD-dependent oxidoreductase compare
MMJJ_RS07350 -3.1 -5.1 4Fe-4S binding protein compare
MMJJ_RS07360 -3.0 -1.7 TIGR00269 family protein compare
MMJJ_RS03055 -3.0 -5.5 hypothetical protein compare
MMJJ_RS03140 -3.0 -14.4 tRNA-dihydrouridine synthase compare
MMJJ_RS04730 -3.0 -3.8 tyrosine decarboxylase MfnA compare
MMJJ_RS07410 -3.0 -5.4 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS03760 -3.0 -6.0 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS05655 -3.0 -6.1 HisA/HisF family protein compare
MMJJ_RS08080 -3.0 -11.3 TIGR00300 family protein compare
MMJJ_RS01765 -2.9 -10.6 winged helix-turn-helix domain-containing protein compare
MMJJ_RS04970 -2.9 -2.9 DUF655 domain-containing protein compare
MMJJ_RS02275 -2.9 -4.9 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06860 -2.9 -4.7 hypothetical protein compare
MMJJ_RS05070 -2.9 -3.0 DNA primase catalytic subunit PriS compare
MMJJ_RS03865 -2.9 -1.9 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS03270 -2.9 -2.2 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS05225 -2.9 -2.0 Gar1/Naf1 family protein compare
MMJJ_RS06255 -2.9 -8.5 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS00550 -2.9 -8.3 AIR synthase-related protein compare
MMJJ_RS05360 -2.9 -8.2 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS00125 -2.9 -3.6 KEOPS complex subunit Cgi121 compare
MMJJ_RS00580 -2.9 -1.8 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS04110 -2.9 -6.5 hypothetical protein compare
MMJJ_RS04150 -2.9 -4.3 DUF5379 domain-containing protein compare
MMJJ_RS06485 -2.9 -3.8 phosphoglycerate kinase compare
MMJJ_RS01755 -2.8 -4.3 ferrous iron transport protein B compare
MMJJ_RS08840 -2.8 -4.6 calcium/sodium antiporter compare
MMJJ_RS06940 -2.8 -11.6 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS03615 -2.8 -5.2 cobalt-precorrin-8 methylmutase compare
MMJJ_RS03005 -2.8 -4.5 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS06225 -2.7 -3.0 adenosylmethionine decarboxylase compare
MMJJ_RS01750 -2.7 -3.8 ferrous iron transport protein A compare
MMJJ_RS07945 -2.7 -3.1 4Fe-4S binding protein compare
MMJJ_RS08005 -2.7 -19.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS03670 -2.7 -7.0 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS05780 -2.7 -4.9 flagellin compare
MMJJ_RS06240 -2.7 -2.8 dihydropteroate synthase-like protein compare
MMJJ_RS08660 -2.6 -4.4 acetylornithine transaminase compare
MMJJ_RS04485 -2.6 -11.8 riboflavin synthase compare
MMJJ_RS04675 -2.6 -7.1 thiamine pyrophosphate-binding protein compare
MMJJ_RS02200 -2.6 -10.0 chorismate pyruvate-lyase family protein compare
MMJJ_RS06155 -2.6 -6.9 phosphatidylglycerophosphatase A compare
MMJJ_RS03160 -2.6 -11.3 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS08250 -2.6 -8.1 hydrogenase maturation peptidase HycI compare
MMJJ_RS05770 -2.6 -2.7 flagellar protein D compare
MMJJ_RS02935 -2.5 -4.5 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS07000 -2.5 -2.7 TrkH family potassium uptake protein compare
MMJJ_RS04700 -2.5 -7.7 deoxyhypusine synthase compare
MMJJ_RS03200 -2.5 -3.4 uroporphyrinogen-III synthase compare
MMJJ_RS04980 -2.5 -5.0 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS00205 -2.5 -5.9 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS05190 -2.5 -11.1 gamma carbonic anhydrase family protein compare
MMJJ_RS08000 -2.5 -12.1 HesA/MoeB/ThiF family protein compare
MMJJ_RS03095 -2.5 -3.5 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS07810 -2.5 -13.7 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMJJ_RS08020 -2.5 -11.6 nucleotidyltransferase domain-containing protein compare
MMJJ_RS01880 -2.5 -3.9 RlmE family RNA methyltransferase compare
MMJJ_RS04790 -2.4 -4.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS05810 -2.4 -6.9 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS04475 -2.4 -6.4 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS08340 -2.4 -4.6 archaeoflavoprotein AfpA compare
MMJJ_RS02055 -2.4 -14.0 GTP 3',8-cyclase MoaA compare
MMJJ_RS00355 -2.4 -2.7 ribonuclease P protein component 4 compare
MMJJ_RS03765 -2.4 -8.4 hypothetical protein compare
MMJJ_RS05295 -2.4 -10.7 cobyrinic acid a,c-diamide synthase compare
MMJJ_RS03660 -2.4 -4.6 DUF447 family protein compare
MMJJ_RS07815 -2.4 -16.6 2-oxoacid:acceptor oxidoreductase family protein compare
MMJJ_RS08795 -2.4 -3.1 phosphoglucosamine mutase compare
MMJJ_RS00450 -2.4 -2.7 DUF126 domain-containing protein compare
MMJJ_RS07805 -2.4 -10.5 ferredoxin family protein compare
MMJJ_RS07660 -2.4 -12.3 carbonic anhydrase compare
MMJJ_RS01810 -2.4 -2.3 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS04995 -2.4 -5.9 Tfx family DNA-binding protein compare
MMJJ_RS05540 -2.3 -16.0 LysR family transcriptional regulator compare
MMJJ_RS00570 -2.3 -3.1 ribonuclease P compare
MMJJ_RS03845 -2.3 -4.0 translation initiation factor IF-2 compare
MMJJ_RS08855 -2.3 -4.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS04145 -2.3 -9.6 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS01345 -2.3 -4.4 (5-formylfuran-3-yl)methyl phosphate synthase compare
MMJJ_RS08480 -2.3 -12.5 hydroxyethylthiazole kinase compare
MMJJ_RS04650 -2.3 -7.4 nitrogenase iron protein compare
MMJJ_RS04505 -2.3 -5.9 CDC48 family AAA ATPase compare
MMJJ_RS06910 -2.3 -3.4 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS08150 -2.3 -16.6 M24 family metallopeptidase compare
MMJJ_RS07995 -2.2 -6.0 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS09055 -2.2 -9.8 NFACT family protein compare
MMJJ_RS07345 -2.2 -5.7 homocysteine biosynthesis protein compare
MMJJ_RS09190 -2.2 -2.9 tryptophan synthase subunit beta compare
MMJJ_RS01600 -2.2 -3.9 radical SAM protein compare
MMJJ_RS06000 -2.2 -7.3 cation:proton antiporter subunit C compare
MMJJ_RS06695 -2.2 -2.3 amidohydrolase compare
MMJJ_RS06040 -2.2 -4.9 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS05445 -2.2 -2.4 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS06805 -2.2 -4.6 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS03125 -2.2 -4.5 GMC oxidoreductase compare
MMJJ_RS03580 -2.2 -4.5 TIGR00303 family protein compare
MMJJ_RS06915 -2.2 -9.9 helix-turn-helix domain-containing protein compare
MMJJ_RS01815 -2.2 -5.6 DUF134 domain-containing protein compare
MMJJ_RS05370 -2.2 -9.6 LysR family transcriptional regulator compare
MMJJ_RS07430 -2.2 -3.8 ribonuclease VapC compare
MMJJ_RS00215 -2.1 -3.1 CCA tRNA nucleotidyltransferase compare
MMJJ_RS06600 -2.1 -2.7 DUF555 domain-containing protein compare
MMJJ_RS08585 -2.1 -10.3 M42 family metallopeptidase compare
MMJJ_RS06215 -2.1 -5.5 agmatinase compare
MMJJ_RS02190 -2.1 -13.1 molybdopterin biosynthesis protein compare
MMJJ_RS07155 -2.1 -8.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS02205 -2.1 -12.7 hypothetical protein compare
MMJJ_RS06015 -2.1 -11.7 Na(+)/H(+) antiporter subunit B compare
MMJJ_RS06185 -2.1 -4.9 cobalamin biosynthesis protein compare
MMJJ_RS01415 -2.0 -2.1 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS08155 -2.0 -4.8 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS08535 -2.0 -4.0 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS03785 -2.0 -3.1 hypothetical protein compare
MMJJ_RS00425 -2.0 -6.5 hypothetical protein compare
MMJJ_RS06865 -2.0 -2.6 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS00370 -2.0 -2.7 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS06785 -2.0 -7.7 RNA ligase partner protein compare
MMJJ_RS08065 -2.0 -3.4 precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT compare
MMJJ_RS04520 -2.0 -4.8 coenzyme F430 synthase compare
MMJJ_RS08405 -2.0 -12.0 nickel-dependent hydrogenase large subunit compare
MMJJ_RS06750 -2.0 -2.6 homoaconitase large subunit compare
MMJJ_RS00415 -2.0 -6.8 DedA family protein compare
MMJJ_RS03965 -1.9 -3.1 DNA-directed RNA polymerase subunit L compare
MMJJ_RS06035 -1.9 -9.1 NADH-quinone oxidoreductase subunit B family protein compare
MMJJ_RS08820 -1.9 -10.2 pyridoxal phosphate-dependent aminotransferase compare
MMJJ_RS05710 -1.9 -3.7 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS01200 -1.9 -3.4 PRC-barrel domain-containing protein compare
MMJJ_RS06025 -1.9 -13.9 4Fe-4S binding protein compare
MMJJ_RS06050 -1.9 -9.1 molybdopterin molybdotransferase MoeA compare


Specific Phenotypes

For 3 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis JJ

For stress Sodium hypophosphite across organisms