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Experiment set9S182 for
Methanococcus maripaludis JJ
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200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS04970
-5.8
-4.0
DUF655 domain-containing protein
compare
MMJJ
_RS04730
-5.3
-3.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS00275
-4.9
-4.7
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03865
-4.8
-3.0
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS03895
-4.8
-6.6
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS04200
-4.6
-9.4
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS01355
-4.5
-4.4
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS03760
-4.5
-6.1
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS07350
-4.4
-5.5
4Fe-4S binding protein
compare
MMJJ
_RS00450
-4.4
-4.0
DUF126 domain-containing protein
compare
MMJJ
_RS05610
-4.3
-6.6
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS01935
-4.2
-6.4
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06485
-4.2
-4.9
phosphoglycerate kinase
compare
MMJJ
_RS06910
-4.2
-5.7
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS03840
-4.0
-6.1
DHH family phosphoesterase
compare
MMJJ
_RS02920
-4.0
-4.2
30S ribosomal protein S27ae
compare
MMJJ
_RS07720
-4.0
-3.3
UPF0058 family protein
compare
MMJJ
_RS09175
-4.0
-2.1
anthranilate synthase component I
compare
MMJJ
_RS06110
-3.9
-3.8
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS00355
-3.9
-4.6
ribonuclease P protein component 4
compare
MMJJ
_RS05620
-3.8
-6.8
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS00600
-3.8
-4.5
hydroxymethylbilane synthase
compare
MMJJ
_RS05330
-3.8
-3.6
DNA polymerase II large subunit
compare
MMJJ
_RS07655
-3.8
-14.2
hypothetical protein
compare
MMJJ
_RS00370
-3.7
-3.0
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS01600
-3.6
-4.5
radical SAM protein
compare
MMJJ
_RS03055
-3.6
-4.7
hypothetical protein
compare
MMJJ
_RS08625
-3.5
-9.3
magnesium/cobalt transporter CorA
compare
MMJJ
_RS03620
-3.4
-7.1
DUF2097 domain-containing protein
compare
MMJJ
_RS05650
-3.2
-4.9
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS05445
-3.2
-2.4
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07725
-3.2
-8.6
DNA primase DnaG
compare
MMJJ
_RS06250
-3.2
-4.4
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS05260
-3.2
-7.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS06860
-3.1
-4.5
hypothetical protein
compare
MMJJ
_RS04155
-3.1
-9.9
hypothetical protein
compare
MMJJ
_RS01870
-3.1
-3.5
methanogenesis marker 15 protein
compare
MMJJ
_RS05490
-3.1
-4.7
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS06625
-3.1
-3.5
pyruvate synthase subunit PorB
compare
MMJJ
_RS08840
-3.1
-5.6
calcium/sodium antiporter
compare
MMJJ
_RS08850
-3.1
-4.5
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS07950
-3.0
-5.4
4Fe-4S binding protein
compare
MMJJ
_RS00270
-3.0
-4.4
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS08055
-3.0
-6.9
methanogenesis marker 14 protein
compare
MMJJ
_RS04675
-3.0
-7.3
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS06180
-3.0
-4.5
tryptophan--tRNA ligase
compare
MMJJ
_RS07000
-3.0
-2.9
TrkH family potassium uptake protein
compare
MMJJ
_RS00125
-3.0
-4.0
KEOPS complex subunit Cgi121
compare
MMJJ
_RS06240
-2.9
-4.6
dihydropteroate synthase-like protein
compare
MMJJ
_RS03110
-2.9
-5.1
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08320
-2.9
-3.3
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS07275
-2.9
-4.3
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS00210
-2.8
-3.6
DUF530 family protein
compare
MMJJ
_RS04685
-2.8
-10.8
carbamoyltransferase HypF
compare
MMJJ
_RS02040
-2.8
-2.9
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS00570
-2.8
-2.9
ribonuclease P
compare
MMJJ
_RS08535
-2.8
-4.4
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07945
-2.8
-4.0
4Fe-4S binding protein
compare
MMJJ
_RS03200
-2.8
-3.8
uroporphyrinogen-III synthase
compare
MMJJ
_RS07810
-2.8
-16.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS06855
-2.8
-3.0
DUF2104 domain-containing protein
compare
MMJJ
_RS02090
-2.8
-6.7
tyramine--L-glutamate ligase
compare
MMJJ
_RS04800
-2.8
-7.9
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06510
-2.8
-4.4
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS01750
-2.7
-4.6
ferrous iron transport protein A
compare
MMJJ
_RS02935
-2.7
-4.7
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS06905
-2.7
-3.5
hypothetical protein
compare
MMJJ
_RS08795
-2.7
-3.3
phosphoglucosamine mutase
compare
MMJJ
_RS03785
-2.7
-3.6
hypothetical protein
compare
MMJJ
_RS07815
-2.7
-16.3
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS00215
-2.6
-3.1
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS04995
-2.6
-8.6
Tfx family DNA-binding protein
compare
MMJJ
_RS07245
-2.6
-7.0
amidohydrolase family protein
compare
MMJJ
_RS03190
-2.6
-4.2
phosphopyruvate hydratase
compare
MMJJ
_RS05380
-2.6
-2.2
hypothetical protein
compare
MMJJ
_RS05575
-2.6
-6.1
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS06225
-2.6
-3.0
adenosylmethionine decarboxylase
compare
MMJJ
_RS05415
-2.6
-3.8
hypothetical protein
compare
MMJJ
_RS01755
-2.6
-3.5
ferrous iron transport protein B
compare
MMJJ
_RS05155
-2.6
-5.1
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS03615
-2.5
-4.1
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS05935
-2.5
-2.6
Era-like GTP-binding protein
compare
MMJJ
_RS04655
-2.5
-5.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS06255
-2.5
-8.1
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS05065
-2.5
-7.5
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS08660
-2.5
-4.6
acetylornithine transaminase
compare
MMJJ
_RS03670
-2.5
-6.3
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS08620
-2.5
-3.3
DUF373 family protein
compare
MMJJ
_RS05930
-2.4
-2.5
cell division protein SepF
compare
MMJJ
_RS05655
-2.4
-6.0
HisA/HisF family protein
compare
MMJJ
_RS09190
-2.4
-2.6
tryptophan synthase subunit beta
compare
MMJJ
_RS05995
-2.4
-3.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04975
-2.4
-2.9
glycosyltransferase family 4 protein
compare
MMJJ
_RS00560
-2.4
-4.2
homoisocitrate dehydrogenase
compare
MMJJ
_RS00550
-2.4
-9.1
AIR synthase-related protein
compare
MMJJ
_RS05190
-2.4
-10.5
gamma carbonic anhydrase family protein
compare
MMJJ
_RS04790
-2.4
-5.3
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS08080
-2.4
-11.8
TIGR00300 family protein
compare
MMJJ
_RS06040
-2.3
-5.4
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04050
-2.3
-2.5
dihydroneopterin aldolase family protein
compare
MMJJ
_RS07805
-2.3
-10.3
ferredoxin family protein
compare
MMJJ
_RS07785
-2.3
-2.6
fumarate reductase subunit A
compare
MMJJ
_RS07705
-2.3
-3.2
GTP-binding protein EngB
compare
MMJJ
_RS06875
-2.3
-4.1
hypothetical protein
compare
MMJJ
_RS04520
-2.3
-5.8
coenzyme F430 synthase
compare
MMJJ
_RS07415
-2.3
-3.4
polyprenyl diphosphate synthase
compare
MMJJ
_RS06185
-2.3
-4.5
cobalamin biosynthesis protein
compare
MMJJ
_RS07345
-2.2
-5.4
homocysteine biosynthesis protein
compare
MMJJ
_RS07430
-2.2
-3.4
ribonuclease VapC
compare
MMJJ
_RS01350
-2.2
-5.6
sodium:proton antiporter
compare
MMJJ
_RS05645
-2.2
-3.3
4Fe-4S binding protein
compare
MMJJ
_RS01360
-2.2
-3.6
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS08095
-2.2
-5.5
cobyric acid synthase CobQ
compare
MMJJ
_RS06930
-2.2
-4.1
type II methionyl aminopeptidase
compare
MMJJ
_RS06695
-2.2
-3.6
amidohydrolase
compare
MMJJ
_RS06705
-2.2
-5.9
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS06865
-2.2
-2.5
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03150
-2.1
-8.0
2-phospho-L-lactate transferase
compare
MMJJ
_RS03170
-2.1
-6.5
DUF5612 domain-containing protein
compare
MMJJ
_RS02275
-2.1
-4.3
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07360
-2.1
-2.9
TIGR00269 family protein
compare
MMJJ
_RS06840
-2.1
-4.7
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS03820
-2.1
-4.5
hydrogenase formation protein HypD
compare
MMJJ
_RS06390
-2.1
-2.4
NADPH-dependent F420 reductase
compare
MMJJ
_RS07190
-2.0
-4.9
RtcB family protein
compare
MMJJ
_RS04700
-2.0
-7.4
deoxyhypusine synthase
compare
MMJJ
_RS01345
-2.0
-4.5
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS06725
-2.0
-12.4
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS08250
-2.0
-7.7
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS07665
-2.0
-16.6
formate dehydrogenase subunit alpha
compare
MMJJ
_RS09375
-2.0
-1.9
hypothetical protein
compare
MMJJ
_RS08020
-2.0
-10.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03875
-2.0
-3.8
CBS domain-containing protein
compare
MMJJ
_RS03270
-2.0
-2.4
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS07155
-2.0
-9.2
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07670
-2.0
-15.6
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS00580
-2.0
-3.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS03295
-1.9
-11.7
PHP domain-containing protein
compare
MMJJ
_RS06000
-1.9
-7.8
cation:proton antiporter subunit C
compare
MMJJ
_RS05295
-1.9
-9.9
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS09130
-1.9
-2.5
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS06490
-1.9
-2.8
methanogenesis marker 2 protein
compare
MMJJ
_RS03060
-1.9
-3.1
methanogenesis marker 7 protein
compare
MMJJ
_RS04145
-1.9
-10.7
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS07410
-1.9
-4.4
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS05950
-1.9
-4.6
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS03125
-1.9
-4.7
GMC oxidoreductase
compare
MMJJ
_RS08480
-1.9
-9.7
hydroxyethylthiazole kinase
compare
MMJJ
_RS04615
-1.9
-4.5
methanogenesis marker 3 protein
compare
MMJJ
_RS04485
-1.9
-11.5
riboflavin synthase
compare
MMJJ
_RS05225
-1.9
-1.4
Gar1/Naf1 family protein
compare
MMJJ
_RS06785
-1.9
-8.3
RNA ligase partner protein
compare
MMJJ
_RS04980
-1.8
-4.3
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS04985
-1.8
-2.4
glutamyl-tRNA reductase
compare
MMJJ
_RS08340
-1.8
-5.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS03160
-1.8
-9.4
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS06175
-1.8
-3.8
DUF1743 domain-containing protein
compare
MMJJ
_RS04565
-1.8
-2.8
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS00360
-1.8
-3.4
adenosylhomocysteinase
compare
MMJJ
_RS03005
-1.8
-4.3
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS06220
-1.8
-4.2
polyamine aminopropyltransferase
compare
MMJJ
_RS05070
-1.8
-2.8
DNA primase catalytic subunit PriS
compare
MMJJ
_RS03845
-1.8
-4.3
translation initiation factor IF-2
compare
MMJJ
_RS05540
-1.8
-14.3
LysR family transcriptional regulator
compare
MMJJ
_RS06750
-1.8
-2.2
homoaconitase large subunit
compare
MMJJ
_RS06155
-1.8
-5.9
phosphatidylglycerophosphatase A
compare
MMJJ
_RS08155
-1.7
-3.5
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS06805
-1.7
-3.5
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06015
-1.7
-9.6
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS06025
-1.7
-13.7
4Fe-4S binding protein
compare
MMJJ
_RS05590
-1.7
-2.5
homoserine dehydrogenase
compare
MMJJ
_RS05720
-1.7
-3.4
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS00205
-1.7
-5.8
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS01865
-1.7
-4.1
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS06915
-1.7
-9.8
helix-turn-helix domain-containing protein
compare
MMJJ
_RS01815
-1.7
-4.2
DUF134 domain-containing protein
compare
MMJJ
_RS06010
-1.7
-7.5
hypothetical protein
compare
MMJJ
_RS06760
-1.7
-5.9
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS03500
-1.7
-10.9
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS03660
-1.7
-2.6
DUF447 family protein
compare
MMJJ
_RS06005
-1.7
-7.0
energy conserving hydrogenase EhbF
compare
MMJJ
_RS01410
-1.6
-4.3
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS03815
-1.6
-1.9
nascent polypeptide-associated complex protein
compare
MMJJ
_RS04670
-1.6
-4.0
DUF2117 domain-containing protein
compare
MMJJ
_RS03580
-1.6
-3.2
TIGR00303 family protein
compare
MMJJ
_RS04110
-1.6
-5.7
hypothetical protein
compare
MMJJ
_RS08035
-1.6
-8.0
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS08330
-1.6
-2.0
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS07715
-1.6
-1.9
UbiD family decarboxylase
compare
MMJJ
_RS06700
-1.6
-4.5
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS05360
-1.6
-7.5
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS06035
-1.6
-9.1
NADH-quinone oxidoreductase subunit B family protein
compare
MMJJ
_RS08010
-1.5
-6.0
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS06215
-1.5
-3.6
agmatinase
compare
MMJJ
_RS01690
-1.5
-3.2
methanogenesis marker 12 protein
compare
MMJJ
_RS08405
-1.5
-9.8
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS03650
-1.5
-5.0
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS09055
-1.5
-7.0
NFACT family protein
compare
MMJJ
_RS04770
-1.5
-2.1
formate-dependent phosphoribosylglycinamide formyltransferase
compare
MMJJ
_RS00045
-1.5
-11.2
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
Specific Phenotypes
For 2 genes in this experiment