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Experiment set9S181 for
Methanococcus maripaludis JJ
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200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS04200
-6.0
-10.0
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS03270
-5.8
-4.0
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS05070
-5.7
-4.0
DNA primase catalytic subunit PriS
compare
MMJJ
_RS01935
-5.4
-6.4
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06490
-5.3
-3.7
methanogenesis marker 2 protein
compare
MMJJ
_RS06180
-5.3
-3.7
tryptophan--tRNA ligase
compare
MMJJ
_RS06625
-5.2
-4.6
pyruvate synthase subunit PorB
compare
MMJJ
_RS03620
-4.9
-8.7
DUF2097 domain-containing protein
compare
MMJJ
_RS04970
-4.7
-4.1
DUF655 domain-containing protein
compare
MMJJ
_RS00450
-4.6
-3.8
DUF126 domain-containing protein
compare
MMJJ
_RS03110
-4.4
-5.3
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08850
-4.4
-5.0
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS03840
-4.4
-6.0
DHH family phosphoesterase
compare
MMJJ
_RS01360
-4.4
-4.2
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS07470
-4.3
-3.0
50S ribosome-binding GTPase
compare
MMJJ
_RS00125
-4.2
-4.1
KEOPS complex subunit Cgi121
compare
MMJJ
_RS07000
-4.2
-3.3
TrkH family potassium uptake protein
compare
MMJJ
_RS07655
-4.1
-15.3
hypothetical protein
compare
MMJJ
_RS03820
-4.1
-6.3
hydrogenase formation protein HypD
compare
MMJJ
_RS05590
-4.1
-4.0
homoserine dehydrogenase
compare
MMJJ
_RS08320
-4.1
-5.1
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS01755
-4.1
-4.8
ferrous iron transport protein B
compare
MMJJ
_RS00370
-4.0
-3.9
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS02920
-4.0
-4.3
30S ribosomal protein S27ae
compare
MMJJ
_RS06930
-4.0
-4.8
type II methionyl aminopeptidase
compare
MMJJ
_RS07785
-4.0
-4.7
fumarate reductase subunit A
compare
MMJJ
_RS04975
-4.0
-3.2
glycosyltransferase family 4 protein
compare
MMJJ
_RS08625
-4.0
-9.6
magnesium/cobalt transporter CorA
compare
MMJJ
_RS06875
-3.9
-3.8
hypothetical protein
compare
MMJJ
_RS05260
-3.9
-8.0
ATP-grasp domain-containing protein
compare
MMJJ
_RS06510
-3.8
-5.1
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS06860
-3.7
-5.4
hypothetical protein
compare
MMJJ
_RS05575
-3.7
-6.6
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS01355
-3.7
-5.0
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS00275
-3.7
-3.6
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS05445
-3.6
-3.4
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS03895
-3.6
-5.3
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS05650
-3.5
-4.7
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS04685
-3.5
-12.7
carbamoyltransferase HypF
compare
MMJJ
_RS05490
-3.4
-4.7
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS00570
-3.4
-3.3
ribonuclease P
compare
MMJJ
_RS06695
-3.4
-4.5
amidohydrolase
compare
MMJJ
_RS05620
-3.4
-7.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03615
-3.3
-5.3
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS02045
-3.3
-4.9
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS00215
-3.3
-4.4
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS07950
-3.3
-5.3
4Fe-4S binding protein
compare
MMJJ
_RS01880
-3.3
-4.8
RlmE family RNA methyltransferase
compare
MMJJ
_RS08660
-3.3
-5.2
acetylornithine transaminase
compare
MMJJ
_RS05610
-3.2
-5.9
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03190
-3.2
-4.9
phosphopyruvate hydratase
compare
MMJJ
_RS07360
-3.2
-2.8
TIGR00269 family protein
compare
MMJJ
_RS05720
-3.2
-4.1
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS08055
-3.2
-8.7
methanogenesis marker 14 protein
compare
MMJJ
_RS00270
-3.2
-4.5
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS06485
-3.1
-4.9
phosphoglycerate kinase
compare
MMJJ
_RS04155
-3.1
-10.1
hypothetical protein
compare
MMJJ
_RS08095
-3.1
-5.1
cobyric acid synthase CobQ
compare
MMJJ
_RS06110
-3.1
-3.1
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS07810
-3.0
-15.8
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS04700
-3.0
-8.8
deoxyhypusine synthase
compare
MMJJ
_RS03200
-3.0
-4.0
uroporphyrinogen-III synthase
compare
MMJJ
_RS03865
-3.0
-2.0
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS06225
-3.0
-3.6
adenosylmethionine decarboxylase
compare
MMJJ
_RS08795
-3.0
-3.9
phosphoglucosamine mutase
compare
MMJJ
_RS02275
-3.0
-6.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS04995
-2.9
-6.5
Tfx family DNA-binding protein
compare
MMJJ
_RS03760
-2.9
-5.4
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS02935
-2.9
-5.3
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS07815
-2.9
-17.3
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS05995
-2.9
-3.9
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04790
-2.9
-5.4
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS09375
-2.9
-2.3
hypothetical protein
compare
MMJJ
_RS07705
-2.9
-3.9
GTP-binding protein EngB
compare
MMJJ
_RS09190
-2.9
-3.0
tryptophan synthase subunit beta
compare
MMJJ
_RS03500
-2.9
-14.3
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMJJ
_RS01750
-2.8
-4.3
ferrous iron transport protein A
compare
MMJJ
_RS07725
-2.7
-6.0
DNA primase DnaG
compare
MMJJ
_RS04655
-2.7
-5.7
FAD-dependent oxidoreductase
compare
MMJJ
_RS01415
-2.7
-2.7
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS05225
-2.7
-2.4
Gar1/Naf1 family protein
compare
MMJJ
_RS05190
-2.7
-12.9
gamma carbonic anhydrase family protein
compare
MMJJ
_RS03095
-2.7
-3.9
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS00560
-2.6
-5.8
homoisocitrate dehydrogenase
compare
MMJJ
_RS07190
-2.6
-5.8
RtcB family protein
compare
MMJJ
_RS07350
-2.6
-3.3
4Fe-4S binding protein
compare
MMJJ
_RS04800
-2.6
-8.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS01600
-2.6
-3.9
radical SAM protein
compare
MMJJ
_RS06255
-2.6
-7.8
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS02090
-2.6
-6.4
tyramine--L-glutamate ligase
compare
MMJJ
_RS06910
-2.6
-4.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS03875
-2.6
-4.6
CBS domain-containing protein
compare
MMJJ
_RS08080
-2.6
-11.5
TIGR00300 family protein
compare
MMJJ
_RS03055
-2.6
-5.2
hypothetical protein
compare
MMJJ
_RS07430
-2.6
-4.6
ribonuclease VapC
compare
MMJJ
_RS03125
-2.5
-5.4
GMC oxidoreductase
compare
MMJJ
_RS07805
-2.5
-10.0
ferredoxin family protein
compare
MMJJ
_RS06040
-2.5
-5.6
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03785
-2.5
-3.6
hypothetical protein
compare
MMJJ
_RS05330
-2.5
-3.7
DNA polymerase II large subunit
compare
MMJJ
_RS03670
-2.5
-5.1
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07720
-2.5
-2.8
UPF0058 family protein
compare
MMJJ
_RS00550
-2.4
-9.0
AIR synthase-related protein
compare
MMJJ
_RS05810
-2.4
-8.3
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS04050
-2.4
-2.1
dihydroneopterin aldolase family protein
compare
MMJJ
_RS07945
-2.4
-4.0
4Fe-4S binding protein
compare
MMJJ
_RS01870
-2.4
-2.4
methanogenesis marker 15 protein
compare
MMJJ
_RS01810
-2.4
-3.7
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS01345
-2.4
-4.5
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS07875
-2.4
-2.9
FAD-dependent oxidoreductase
compare
MMJJ
_RS06240
-2.4
-2.5
dihydropteroate synthase-like protein
compare
MMJJ
_RS07345
-2.4
-6.1
homocysteine biosynthesis protein
compare
MMJJ
_RS07665
-2.4
-19.6
formate dehydrogenase subunit alpha
compare
MMJJ
_RS09175
-2.3
-1.8
anthranilate synthase component I
compare
MMJJ
_RS05655
-2.3
-6.7
HisA/HisF family protein
compare
MMJJ
_RS01350
-2.3
-7.3
sodium:proton antiporter
compare
MMJJ
_RS08020
-2.3
-9.7
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS04980
-2.3
-5.7
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS08620
-2.3
-3.7
DUF373 family protein
compare
MMJJ
_RS05065
-2.2
-5.5
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS08250
-2.2
-8.9
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS03150
-2.2
-6.7
2-phospho-L-lactate transferase
compare
MMJJ
_RS06840
-2.2
-4.5
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS04730
-2.2
-3.0
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06220
-2.2
-6.7
polyamine aminopropyltransferase
compare
MMJJ
_RS03580
-2.2
-4.4
TIGR00303 family protein
compare
MMJJ
_RS07670
-2.2
-16.4
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS06865
-2.2
-2.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS06155
-2.2
-6.8
phosphatidylglycerophosphatase A
compare
MMJJ
_RS06725
-2.2
-12.1
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS04675
-2.2
-7.0
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS03005
-2.2
-4.5
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS00205
-2.2
-6.6
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS07275
-2.2
-4.1
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS03160
-2.2
-10.0
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS08325
-2.2
-3.8
glycosyltransferase family 2 protein
compare
MMJJ
_RS07410
-2.2
-6.0
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS04110
-2.2
-6.6
hypothetical protein
compare
MMJJ
_RS06390
-2.1
-3.0
NADPH-dependent F420 reductase
compare
MMJJ
_RS08330
-2.1
-3.5
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS03170
-2.0
-7.7
DUF5612 domain-containing protein
compare
MMJJ
_RS04565
-2.0
-2.9
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS06215
-2.0
-6.1
agmatinase
compare
MMJJ
_RS01830
-2.0
-2.8
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS02200
-2.0
-9.7
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS04145
-2.0
-8.2
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS06915
-2.0
-12.4
helix-turn-helix domain-containing protein
compare
MMJJ
_RS07155
-2.0
-8.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS00580
-2.0
-1.9
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS03295
-2.0
-11.9
PHP domain-containing protein
compare
MMJJ
_RS06700
-2.0
-5.0
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS06785
-2.0
-9.4
RNA ligase partner protein
compare
MMJJ
_RS09055
-1.9
-7.4
NFACT family protein
compare
MMJJ
_RS08155
-1.9
-4.6
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS05950
-1.9
-3.4
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS04520
-1.9
-5.6
coenzyme F430 synthase
compare
MMJJ
_RS00355
-1.9
-4.2
ribonuclease P protein component 4
compare
MMJJ
_RS01200
-1.9
-3.4
PRC-barrel domain-containing protein
compare
MMJJ
_RS05295
-1.9
-11.0
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS01865
-1.9
-3.9
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS05930
-1.9
-3.3
cell division protein SepF
compare
MMJJ
_RS06855
-1.9
-2.2
DUF2104 domain-containing protein
compare
MMJJ
_RS08480
-1.9
-8.9
hydroxyethylthiazole kinase
compare
MMJJ
_RS05535
-1.9
-11.1
hypothetical protein
compare
MMJJ
_RS07245
-1.8
-5.2
amidohydrolase family protein
compare
MMJJ
_RS06170
-1.8
-9.0
hypothetical protein
compare
MMJJ
_RS05540
-1.8
-14.6
LysR family transcriptional regulator
compare
MMJJ
_RS04485
-1.8
-10.3
riboflavin synthase
compare
MMJJ
_RS06010
-1.8
-6.7
hypothetical protein
compare
MMJJ
_RS03845
-1.8
-3.5
translation initiation factor IF-2
compare
MMJJ
_RS05380
-1.8
-2.2
hypothetical protein
compare
MMJJ
_RS08335
-1.8
-2.0
ABC transporter ATP-binding protein
compare
MMJJ
_RS04505
-1.8
-6.0
CDC48 family AAA ATPase
compare
MMJJ
_RS07660
-1.8
-12.4
carbonic anhydrase
compare
MMJJ
_RS05155
-1.8
-5.4
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS06025
-1.8
-14.1
4Fe-4S binding protein
compare
MMJJ
_RS06015
-1.8
-10.2
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS06760
-1.8
-5.5
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS06175
-1.8
-3.5
DUF1743 domain-containing protein
compare
MMJJ
_RS06005
-1.8
-8.6
energy conserving hydrogenase EhbF
compare
MMJJ
_RS04595
-1.8
-5.4
hypothetical protein
compare
MMJJ
_RS06185
-1.7
-4.6
cobalamin biosynthesis protein
compare
MMJJ
_RS08340
-1.7
-4.4
archaeoflavoprotein AfpA
compare
MMJJ
_RS03650
-1.7
-7.0
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS08840
-1.7
-5.2
calcium/sodium antiporter
compare
MMJJ
_RS08870
-1.7
-2.1
2-isopropylmalate synthase
compare
MMJJ
_RS06750
-1.7
-2.6
homoaconitase large subunit
compare
MMJJ
_RS08535
-1.7
-3.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS06000
-1.7
-5.5
cation:proton antiporter subunit C
compare
MMJJ
_RS06020
-1.7
-6.3
hypothetical protein
compare
MMJJ
_RS03660
-1.7
-2.7
DUF447 family protein
compare
MMJJ
_RS08405
-1.7
-11.0
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS04770
-1.7
-2.1
formate-dependent phosphoribosylglycinamide formyltransferase
compare
MMJJ
_RS01500
-1.6
-6.9
transcriptional regulator
compare
MMJJ
_RS08010
-1.6
-7.9
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07170
-1.6
-4.2
pyridoxal phosphate-dependent aminotransferase
compare
MMJJ
_RS06905
-1.6
-1.7
hypothetical protein
compare
MMJJ
_RS06805
-1.6
-2.7
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS08855
-1.6
-5.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS00055
-1.6
-10.4
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
Specific Phenotypes
For 2 genes in this experiment