Experiment set9S178 for Methanococcus maripaludis JJ

Compare to:

Formate 100 mM hypophosphite

200 most detrimental genes:

  gene name fitness t score description  
MMJJ_RS08010 +5.6 14.7 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS07265 +5.4 22.4 tRNA (adenine-N1)-methyltransferase compare
MMJJ_RS06505 +4.4 15.6 prephenate dehydratase compare
MMJJ_RS09035 +4.1 2.5 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS07225 +3.6 12.6 coenzyme F420 hydrogenase subunit gamma compare
MMJJ_RS07235 +3.5 17.7 coenzyme F420 hydrogenase subunit alpha compare
MMJJ_RS04010 +2.8 6.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMJJ_RS06225 +2.5 4.1 adenosylmethionine decarboxylase compare
MMJJ_RS05165 +2.5 5.6 class I SAM-dependent methyltransferase compare
MMJJ_RS09020 +2.5 2.0 hypothetical protein compare
MMJJ_RS07220 +2.4 12.6 coenzyme F420 hydrogenase subunit beta compare
MMJJ_RS07230 +2.3 9.3 coenzyme F420-reducing hydrogenase, FrhD protein compare
MMJJ_RS07015 +2.3 2.7 PFL family protein compare
MMJJ_RS00125 +2.2 3.7 KEOPS complex subunit Cgi121 compare
MMJJ_RS04415 +2.2 9.8 hypothetical protein compare
MMJJ_RS03200 +2.2 2.9 uroporphyrinogen-III synthase compare
MMJJ_RS08325 +2.0 2.2 glycosyltransferase family 2 protein compare
MMJJ_RS03270 +1.9 3.1 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS09335 +1.9 1.9 hypothetical protein compare
MMJJ_RS03225 +1.8 1.7 4Fe-4S binding protein compare
MMJJ_RS04730 +1.8 2.7 tyrosine decarboxylase MfnA compare
MMJJ_RS06585 +1.8 2.6 alanine racemase compare
MMJJ_RS03745 +1.7 2.1 N-glycosylase/DNA lyase compare
MMJJ_RS07190 +1.6 3.2 RtcB family protein compare
MMJJ_RS09120 +1.6 1.8 aspartate kinase compare
MMJJ_RS05765 +1.6 1.3 flagellar protein E compare
MMJJ_RS05935 +1.6 1.8 Era-like GTP-binding protein compare
MMJJ_RS03345 +1.5 1.5 hypothetical protein compare
MMJJ_RS01415 +1.5 2.3 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS06180 +1.5 2.0 tryptophan--tRNA ligase compare
MMJJ_RS07630 +1.5 7.2 hypothetical protein compare
MMJJ_RS03965 +1.5 2.7 DNA-directed RNA polymerase subunit L compare
MMJJ_RS01375 +1.4 2.3 tetrahydromethanopterin:alpha-L-glutamate ligase compare
MMJJ_RS07705 +1.4 1.7 GTP-binding protein EngB compare
MMJJ_RS06745 +1.4 1.8 energy-coupling factor ABC transporter permease compare
MMJJ_RS05720 +1.4 1.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS06380 +1.4 1.0 signal recognition particle protein Srp54 compare
MMJJ_RS00345 +1.4 2.3 4-hydroxy-tetrahydrodipicolinate reductase compare
MMJJ_RS01530 +1.4 2.0 YwbE family protein compare
MMJJ_RS05995 +1.4 2.3 ATP-binding cassette domain-containing protein compare
MMJJ_RS00570 +1.4 1.9 ribonuclease P compare
MMJJ_RS06485 +1.4 2.1 phosphoglycerate kinase compare
MMJJ_RS03230 +1.4 1.8 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS04770 +1.3 2.8 formate-dependent phosphoribosylglycinamide formyltransferase compare
MMJJ_RS00355 +1.3 1.8 ribonuclease P protein component 4 compare
MMJJ_RS01405 +1.3 1.5 proline--tRNA ligase compare
MMJJ_RS01360 +1.3 1.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS05070 +1.3 1.5 DNA primase catalytic subunit PriS compare
MMJJ_RS01690 +1.3 1.7 methanogenesis marker 12 protein compare
MMJJ_RS01600 +1.3 1.5 radical SAM protein compare
MMJJ_RS01870 +1.3 0.9 methanogenesis marker 15 protein compare
MMJJ_RS05330 +1.3 0.9 DNA polymerase II large subunit compare
MMJJ_RS03045 +1.3 2.0 hypothetical protein compare
MMJJ_RS06110 +1.3 1.2 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS03635 +1.2 2.4 methionine--tRNA ligase compare
MMJJ_RS08190 +1.2 2.5 hypothetical protein compare
MMJJ_RS06840 +1.2 1.7 nickel-dependent hydrogenase large subunit compare
MMJJ_RS08130 +1.2 1.2 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS05870 +1.2 3.4 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMJJ_RS01880 +1.2 1.6 RlmE family RNA methyltransferase compare
MMJJ_RS07715 +1.2 2.4 UbiD family decarboxylase compare
MMJJ_RS06880 +1.2 1.4 EhaG family protein compare
MMJJ_RS06875 +1.2 1.9 hypothetical protein compare
MMJJ_RS03845 +1.2 2.0 translation initiation factor IF-2 compare
MMJJ_RS04750 +1.2 5.6 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS06665 +1.2 4.6 DUF3236 domain-containing protein compare
MMJJ_RS06240 +1.2 1.9 dihydropteroate synthase-like protein compare
MMJJ_RS06865 +1.2 2.2 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS00180 +1.1 5.4 DNA topoisomerase I compare
MMJJ_RS07470 +1.1 0.8 50S ribosome-binding GTPase compare
MMJJ_RS03245 +1.1 0.7 UMP kinase compare
MMJJ_RS08795 +1.1 1.0 phosphoglucosamine mutase compare
MMJJ_RS05595 +1.0 1.6 hypothetical protein compare
MMJJ_RS08660 +1.0 1.2 acetylornithine transaminase compare
MMJJ_RS04755 +1.0 5.5 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS03310 +1.0 1.7 hypothetical protein compare
MMJJ_RS05420 +1.0 1.4 DNA-directed DNA polymerase II small subunit compare
MMJJ_RS00195 +1.0 1.5 precorrin-3B C(17)-methyltransferase compare
MMJJ_RS06375 +1.0 2.1 UbiX family flavin prenyltransferase compare
MMJJ_RS03760 +1.0 1.5 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS07875 +1.0 0.7 FAD-dependent oxidoreductase compare
MMJJ_RS08095 +1.0 1.8 cobyric acid synthase CobQ compare
MMJJ_RS05590 +1.0 0.9 homoserine dehydrogenase compare
MMJJ_RS03190 +1.0 1.1 phosphopyruvate hydratase compare
MMJJ_RS08555 +1.0 1.7 redox-regulated ATPase YchF compare
MMJJ_RS06200 +1.0 1.5 phosphoglycerate dehydrogenase compare
MMJJ_RS08410 +1.0 2.0 CBS domain-containing protein compare
MMJJ_RS05415 +1.0 0.9 hypothetical protein compare
MMJJ_RS07645 +1.0 4.2 selenium-binding protein compare
MMJJ_RS01960 +0.9 2.0 glycosyltransferase family 2 protein compare
MMJJ_RS03490 +0.9 1.4 ribonuclease VapC compare
MMJJ_RS01860 +0.9 5.4 tRNA guanosine(15) transglycosylase TgtA compare
MMJJ_RS01200 +0.9 0.6 PRC-barrel domain-containing protein compare
MMJJ_RS08535 +0.9 1.3 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS04700 +0.9 2.0 deoxyhypusine synthase compare
MMJJ_RS09130 +0.9 0.9 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS02245 +0.9 1.7 DUF432 domain-containing protein compare
MMJJ_RS07370 +0.9 1.8 tRNA 4-thiouridine(8) synthase ThiI compare
MMJJ_RS00430 +0.9 1.4 ribonuclease Z compare
MMJJ_RS06705 +0.9 1.7 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS00275 +0.9 1.1 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS00050 +0.9 2.4 AAA family ATPase compare
MMJJ_RS07345 +0.9 2.5 homocysteine biosynthesis protein compare
MMJJ_RS05005 +0.9 2.0 hypothetical protein compare
MMJJ_RS08485 +0.9 3.0 Lrp/AsnC family transcriptional regulator compare
MMJJ_RS01440 +0.9 2.6 NCS2 family permease compare
MMJJ_RS09135 +0.9 3.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMJJ_RS04975 +0.9 0.8 glycosyltransferase family 4 protein compare
MMJJ_RS03370 +0.8 2.2 hypothetical protein compare
MMJJ_RS01830 +0.8 1.0 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS05490 +0.8 0.6 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS04760 +0.8 5.8 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS06215 +0.8 1.5 agmatinase compare
MMJJ_RS03815 +0.8 0.8 nascent polypeptide-associated complex protein compare
MMJJ_RS07170 +0.8 1.1 pyridoxal phosphate-dependent aminotransferase compare
MMJJ_RS07955 +0.8 4.0 ThiF family adenylyltransferase compare
MMJJ_RS04125 +0.8 4.0 tRNA (guanine(10)-N(2))-dimethyltransferase compare
MMJJ_RS01410 +0.8 2.2 archaeal proteasome endopeptidase complex subunit beta compare
MMJJ_RS06490 +0.8 1.0 methanogenesis marker 2 protein compare
MMJJ_RS05575 +0.8 1.2 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS01425 +0.8 1.7 cell wall-binding protein compare
MMJJ_RS03945 +0.8 4.6 mechanosensitive ion channel family protein compare
MMJJ_RS03865 +0.8 0.6 phosphoribosyl-AMP cyclohydrolase compare
MMJJ_RS03960 +0.8 4.6 DUF2067 domain-containing protein compare
MMJJ_RS07785 +0.8 0.9 fumarate reductase subunit A compare
MMJJ_RS06220 +0.8 1.7 polyamine aminopropyltransferase compare
MMJJ_RS09380 +0.8 1.2 hypothetical protein compare
MMJJ_RS00360 +0.8 0.7 adenosylhomocysteinase compare
MMJJ_RS01965 +0.8 2.2 radical SAM protein compare
MMJJ_RS03185 +0.8 1.4 alanine--tRNA ligase compare
MMJJ_RS08850 +0.7 0.9 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS05780 +0.7 1.0 flagellin compare
MMJJ_RS05170 +0.7 4.1 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS00210 +0.7 0.7 DUF530 family protein compare
MMJJ_RS07960 +0.7 1.2 quinolinate synthase NadA compare
MMJJ_RS07725 +0.7 1.8 DNA primase DnaG compare
MMJJ_RS06935 +0.7 4.2 GTP-binding protein compare
MMJJ_RS09105 +0.7 2.1 AI-2E family transporter compare
MMJJ_RS01755 +0.7 0.7 ferrous iron transport protein B compare
MMJJ_RS03595 +0.7 3.3 hypothetical protein compare
MMJJ_RS05710 +0.7 1.1 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS08810 +0.7 0.6 DUF4040 domain-containing protein compare
MMJJ_RS08065 +0.7 1.6 precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT compare
MMJJ_RS04620 +0.7 0.9 homocitrate synthase family protein compare
MMJJ_RS04525 +0.7 1.7 hypothetical protein compare
MMJJ_RS00285 +0.7 4.0 UPF0254 family protein compare
MMJJ_RS08625 +0.7 1.4 magnesium/cobalt transporter CorA compare
MMJJ_RS08500 +0.7 2.1 L-sulfolactate dehydrogenase compare
MMJJ_RS01475 +0.7 0.5 signal recognition particle-docking protein FtsY compare
MMJJ_RS01495 +0.7 3.1 Na+/H+ antiporter NhaC family protein compare
MMJJ_RS07750 +0.7 1.1 class III signal peptide-containing protein compare
MMJJ_RS08405 +0.7 2.3 nickel-dependent hydrogenase large subunit compare
MMJJ_RS07275 +0.7 0.5 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS03095 +0.7 0.6 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS07000 +0.7 0.6 TrkH family potassium uptake protein compare
MMJJ_RS00475 +0.7 0.6 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS01815 +0.7 1.1 DUF134 domain-containing protein compare
MMJJ_RS07950 +0.7 1.0 4Fe-4S binding protein compare
MMJJ_RS07945 +0.6 0.8 4Fe-4S binding protein compare
MMJJ_RS00765 +0.6 1.8 DUF4013 domain-containing protein compare
MMJJ_RS00555 +0.6 3.3 hypothetical protein compare
MMJJ_RS02900 +0.6 1.4 hypothetical protein compare
MMJJ_RS01855 +0.6 3.8 MBL fold metallo-hydrolase compare
MMJJ_RS08575 +0.6 1.3 hypothetical protein compare
MMJJ_RS01875 +0.6 1.0 global nitrogen regulator NrpR compare
MMJJ_RS06175 +0.6 0.7 DUF1743 domain-containing protein compare
MMJJ_RS03940 +0.6 3.7 DMT family transporter compare
MMJJ_RS07650 +0.6 4.2 formate/nitrite transporter family protein compare
MMJJ_RS08490 +0.6 1.6 rubrerythrin family protein compare
MMJJ_RS08620 +0.6 1.1 DUF373 family protein compare
MMJJ_RS02125 +0.6 1.4 hypothetical protein compare
MMJJ_RS04780 +0.6 1.9 nucleic acid-binding protein compare
MMJJ_RS03005 +0.6 0.6 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS03660 +0.6 0.7 DUF447 family protein compare
MMJJ_RS04800 +0.6 1.4 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS03125 +0.6 1.1 GMC oxidoreductase compare
MMJJ_RS00580 +0.6 0.6 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS06140 +0.6 3.7 RimK family alpha-L-glutamate ligase compare
MMJJ_RS03875 +0.6 0.8 CBS domain-containing protein compare
MMJJ_RS06480 +0.6 2.8 hypothetical protein compare
MMJJ_RS03110 +0.6 0.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS03175 +0.6 1.9 zinc metalloprotease HtpX compare
MMJJ_RS01520 +0.6 1.7 helix-turn-helix transcriptional regulator compare
MMJJ_RS05445 +0.6 0.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS04175 +0.6 2.6 hypothetical protein compare
MMJJ_RS07685 +0.5 1.8 glycogen/starch synthase compare
MMJJ_RS04225 +0.5 1.9 aldo/keto reductase compare
MMJJ_RS07975 +0.5 1.7 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS01420 +0.5 2.4 hypothetical protein compare
MMJJ_RS04520 +0.5 1.1 coenzyme F430 synthase compare
MMJJ_RS00370 +0.5 0.4 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS05650 +0.5 0.5 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS06885 +0.5 0.5 EhaF family protein compare
MMJJ_RS07970 +0.5 0.7 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS06740 +0.5 1.8 energy-coupling factor ABC transporter substrate-binding protein compare
MMJJ_RS08200 +0.5 3.7 surface protein, anchor region compare
MMJJ_RS03835 +0.5 1.0 DUF504 domain-containing protein compare
MMJJ_RS01250 +0.5 1.7 hypothetical protein compare
MMJJ_RS06165 +0.5 2.8 archaeosine synthase subunit alpha compare
MMJJ_RS03445 +0.5 1.9 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis JJ

For stress Sodium hypophosphite across organisms