Experiment set9IT081 for Sinorhizobium meliloti 1021

Compare to:

Protocatechuic Acid carbon source

200 most important genes:

  gene name fitness t score description  
SMc02766 -7.9 -12.2 tryptophan synthase subunit beta compare
SMc00236 -7.9 -5.5 Indole-3-glycerol phosphate synthase compare
SMc02767 -7.7 -5.3 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00235 -7.2 -5.0 anthranilate phosphoribosyltransferase compare
SMc02572 -7.0 -5.4 imidazole glycerol phosphate synthase subunit HisH compare
SMc01494 -6.9 -14.1 phosphoserine phosphatase compare
SMc02569 -6.8 -4.7 imidazole glycerol phosphate synthase subunit HisF compare
SMc02725 -6.7 -7.9 anthranilate synthase compare
SMc02765 -6.6 -16.6 tryptophan synthase subunit alpha compare
SM_b20588 -6.6 -6.4 CoA-transferase subunit B protein compare
SMc04045 -6.4 -7.6 dihydroxy-acid dehydratase compare
SMc00711 -6.3 -4.3 cyclohexadienyl dehydrogenase compare
SMa1635 -6.2 -2.4 hypothetical protein compare
SMc00640 -6.1 -7.3 phosphoserine aminotransferase compare
SMc02562 -6.1 -4.2 phosphoenolpyruvate carboxykinase compare
SMc02123 -6.0 -4.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc04028 -5.9 -12.7 glutamate synthase compare
SM_b20589 -5.9 -6.9 beta-ketoadipyl CoA thiolase conserved
SMc01843 -5.9 -12.6 5,10-methylenetetrahydrofolate reductase compare
SMc02838 -5.8 -8.0 phosphoglyceromutase compare
SMc01801 -5.8 -3.8 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00293 -5.8 -12.4 homoserine dehydrogenase compare
SMc03797 -5.6 -10.5 homoserine O-succinyltransferase compare
SMc01726 -5.5 -4.4 acetylglutamate kinase compare
SMc02138 -5.5 -9.2 acetylornithine transaminase compare
SMc01054 -5.5 -4.9 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00918 -5.4 -9.0 ATP phosphoribosyltransferase regulatory subunit compare
SMc01431 -5.3 -12.8 acetolactate synthase 3 catalytic subunit compare
SMc03112 -5.2 -18.3 B12-dependent methionine synthase compare
SMc00917 -5.2 -5.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02137 -5.2 -3.6 ornithine carbamoyltransferase compare
SMc03823 -5.1 -13.2 isopropylmalate isomerase large subunit compare
SMc03979 -5.0 -3.5 glyceraldehyde-3-phosphate dehydrogenase compare
SMc04405 -5.0 -8.4 3-isopropylmalate dehydrogenase compare
SMc04026 -5.0 -7.6 glutamate synthase compare
SM_b20587 -5.0 -10.7 CoA-transferase subunit A protein compare
SMc00641 -4.9 -4.8 D-3-phosphoglycerate dehydrogenase compare
SMc02899 -4.9 -11.0 prephenate dehydratase compare
SMc01028 -4.8 -16.5 phosphopyruvate hydratase compare
SMc02717 -4.8 -15.4 2-isopropylmalate synthase compare
SMc00090 -4.6 -11.9 sulfate adenylyltransferase compare
SMc02124 -4.6 -14.8 nitrite reductase compare
SMc01004 -4.5 -7.8 phosphoribosyl-AMP cyclohydrolase compare
SMc04088 -4.4 -9.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00131 -4.4 -16.8 transcriptional regulator compare
SM_b20955 -4.3 -4.2 endo-beta-1,3-1,4-glycanase compare
SMc03777 -4.2 -8.5 gamma-glutamyl phosphate reductase compare
SMc00481 -4.2 -19.1 hypothetical protein compare
SMc00993 -4.2 -10.2 phosphoribosylamine--glycine ligase compare
SMc03981 -4.2 -4.2 phosphoglycerate kinase compare
SMc02570 -4.1 -6.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00495 -4.0 -5.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02217 -4.0 -7.6 O-succinylhomoserine sulfhydrylase compare
SMc00488 -3.9 -17.3 phosphoribosylformylglycinamidine synthase II compare
SMc00615 -3.9 -9.6 phosphoribosylaminoimidazole synthetase compare
SMc02307 -3.9 -7.4 histidinol dehydrogenase compare
SM_b20579 -3.9 -9.5 beta-ketoadipate enol-lactone hydrolase conserved
SMc03795 -3.8 -2.0 isopropylmalate isomerase small subunit compare
SMc00414 -3.8 -10.7 hypothetical protein compare
SMc00092 -3.8 -8.5 phosphoadenosine phosphosulfate reductase compare
SMc03974 -3.7 -4.0 hypothetical protein compare
SMc00554 -3.7 -9.5 amidophosphoribosyltransferase compare
SMc00614 -3.7 -7.4 phosphoribosylglycinamide formyltransferase compare
SMc02165 -3.6 -7.7 orotate phosphoribosyltransferase compare
SMc02975 -3.6 -8.3 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc02755 -3.6 -5.4 S-adenosyl-L-homocysteine hydrolase compare
SMc01770 -3.6 -1.6 serine hydroxymethyltransferase compare
SMc04346 -3.5 -7.0 ketol-acid reductoisomerase compare
SMc01053 -3.5 -4.9 siroheme synthase compare
SMc00017 -3.5 -1.8 homoserine kinase compare
SMc03776 -3.5 -3.7 gamma-glutamyl kinase compare
SMc00294 -3.4 -11.3 aminotransferase compare
SMc04002 -3.4 -5.7 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03069 -3.4 -3.1 6-phosphogluconolactonase compare
SM_b21176 -3.4 -6.4 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02707 -3.3 -5.9 hypothetical protein compare
SMc00493 -3.3 -5.6 phosphoribosylformylglycinamidine synthase I compare
SMc01430 -3.2 -6.2 acetolactate synthase 3 regulatory subunit compare
SMc01578 -3.2 -9.9 aspartate aminotransferase compare
SMc00091 -3.2 -12.1 sulfate adenylyltransferase compare
SMc02166 -3.2 -8.7 dihydroorotase compare
SMc00876 -3.2 -3.1 ATP-binding MRP protein compare
SMc02753 -3.2 -1.2 PTS system transporter subunit IIA compare
SM_b21177 -3.1 -8.6 phosphate uptake ABC transporter ATP-binding protein compare
SMc02245 -3.1 -5.2 dihydroorotate dehydrogenase 2 compare
SMc02246 -3.1 -1.2 hypothetical protein compare
SMc03878 -3.0 -4.0 acetoacetyl-CoA reductase compare
SMc01360 -2.9 -2.8 aspartate carbamoyltransferase catalytic subunit compare
SM_b21174 -2.9 -5.5 phosphate uptake ABC transporter permease compare
SMc00296 -2.9 -9.2 POLY3-hydroxybutyrate polymerase compare
SMc00412 -2.8 -5.3 orotidine 5'-phosphate decarboxylase compare
SMc01881 -2.7 -3.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00494 -2.7 -2.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc01220 -2.4 -5.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SM_b20586 -2.4 -3.0 IclR family transcriptional regulator compare
SMc02407 -2.4 -7.4 hypothetical protein compare
SMc04001 -2.3 -1.5 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SM_b20576 -2.3 -7.4 protocatechuate 3,4-dioxygenase subunit alpha conserved
SMc01361 -2.3 -2.2 dihydroorotase compare
SMc02050 -2.3 -4.7 trigger factor compare
SM_b21102 -2.3 -10.9 transcriptional regulator compare
SMc02695 -2.2 -5.1 GTP-dependent nucleic acid-binding protein EngD compare
SMc01880 -2.1 -1.4 pantoate--beta-alanine ligase compare
SMc02365 -2.1 -6.9 protease precursor protein compare
SMc02574 -2.0 -3.4 imidazoleglycerol-phosphate dehydratase compare
SMc03978 -2.0 -1.4 transketolase compare
SMc02095 -2.0 -7.9 hypothetical protein compare
SM_b20577 -2.0 -4.5 protocatechuate 3,4-dioxygenase subunit beta conserved
SMc02640 -2.0 -4.6 UDP-glucuronic acid epimerase compare
SMc00404 -2.0 -1.5 hypothetical protein compare
SMc03229 -1.9 -1.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SM_b20578 -1.9 -3.2 gamma carboxymuconolactone decarboxylase compare
SMc00580 -1.9 -2.5 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc04085 -1.9 -4.9 hypothetical protein compare
SMc02850 -1.9 -1.3 DNA polymerase I compare
SMc03127 -1.8 -1.5 ABC transporter permease compare
SM_b21175 -1.8 -4.4 phosphate uptake ABC transporter permease compare
SMc02641 -1.8 -2.3 UDP-glucose 6-dehydrogenase compare
SMc01280 -1.8 -2.1 protease compare
SMc02983 -1.7 -6.1 ornithine, DAP, or arginine decarboxylase compare
SMc01850 -1.7 -2.7 hypothetical protein compare
SM_b20563 -1.7 -3.1 hypothetical protein compare
SMc00705 -1.7 -6.4 signal peptide protein compare
SMc02229 -1.7 -8.6 acyl-CoA dehydrogenase compare
SMc00405 -1.7 -7.7 hypothetical protein compare
SMc01852 -1.6 -7.3 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc03746 -1.6 -2.6 hypothetical protein compare
SMa1924 -1.5 -1.0 hypothetical protein compare
SMc02724 -1.5 -2.4 hypothetical protein compare
SM_b20948 -1.5 -1.6 glucosyltransferase compare
SMc04330 -1.5 -1.9 trimethylamine methyltransferase compare
SMc00948 -1.5 -7.0 glutamine synthetase compare
SMc00492 -1.5 -0.8 hypothetical protein compare
SMc02403 -1.5 -10.1 murein transglycosylase compare
SM_b21347 -1.5 -2.0 pectin degradation protein compare
SM_b20942 -1.5 -3.7 UDP glucose 4-epimerase compare
SM_b21000 -1.5 -8.9 transporter compare
SMa2289 -1.5 -1.5 hypothetical protein compare
SMc00025 -1.5 -6.0 pyruvate phosphate dikinase compare
SMc02228 -1.5 -4.2 acetyl-CoA acetyltransferase compare
SMc02434 -1.4 -3.3 hypothetical protein compare
SMc01579 -1.4 -1.5 hypothetical protein compare
SMc00450 -1.4 -1.3 protoheme IX farnesyltransferase compare
SMc02367 -1.4 -6.4 sensor histidine kinase transmembrane protein compare
SMc01260 -1.4 -3.2 transcriptional regulator compare
SMc02677 -1.4 -4.3 pyrroline-5-carboxylate reductase compare
SMc02812 -1.4 -1.7 hypothetical protein compare
SM_b21213 -1.4 -4.3 serinethreonine protein phosphatase compare
SMc02048 -1.4 -6.5 glycine cleavage system protein H compare
SMc02510 -1.4 -0.7 ferric uptake regulation protein compare
SMc01472 -1.3 -1.4 50S ribosomal protein L11 methyltransferase compare
SM_b20509 -1.3 -2.6 transcriptional regulator compare
SMc04042 -1.3 -4.0 monophosphatase compare
SMc00349 -1.3 -5.7 GTP-binding protein LepA compare
SMc02145 -1.3 -0.7 signal peptide protein compare
SMc00914 -1.3 -2.1 oxidoreductase compare
SMc02141 -1.3 -1.2 phosphate transporter PhoU compare
SMc02778 -1.3 -1.3 hydroxyacid aldolase compare
SMc03763 -1.3 -0.8 cytosine-specific methyltransferase compare
SMc03836 -1.2 -1.5 acyl-CoA thioesterase i protein compare
SMc02280 -1.2 -1.7 hypothetical protein compare
SMc02227 -1.2 -3.8 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc03184 -1.2 -1.1 PH adaptation potassium efflux system G transmembrane protein compare
SMc00013 -1.2 -1.3 cytochrome C oxidase subunit III transmembrane protein compare
SMc01933 -1.2 -1.5 hypothetical protein compare
SMc02143 -1.2 -2.1 phosphate ABC transporter permease compare
SM_b21487 -1.1 -6.5 cytochrome o ubiquinol oxidase subunit II compare
SM_b21524 -1.1 -2.4 septum formation inhibitor compare
SMc03780 -1.1 -3.2 hypothetical protein compare
SMc00815 -1.1 -0.7 inosine 5'-monophosphate dehydrogenase compare
SMc02564 -1.1 -2.2 LysM domain/BON superfamily protein compare
SMc02144 -1.1 -2.0 phosphate ABC transporter permease compare
SMc00073 -1.1 -1.2 hypothetical protein compare
SMc02142 -1.1 -2.3 phosphate transporter ATP-binding protein compare
SMc02366 -1.1 -6.9 transcriptional regulator compare
SMc00987 -1.1 -1.7 hypothetical protein compare
SMc04348 -1.1 -1.0 transcriptional regulator compare
SMc01206 -1.1 -1.2 queuine tRNA-ribosyltransferase compare
SMc00302 -1.1 -0.9 hypothetical protein compare
SMc01842 -1.1 -1.4 methyltransferase transcription regulator protein compare
SMa1658 -1.0 -1.6 hypothetical protein compare
SMc02276 -1.0 -4.5 nicotinate phosphoribosyltransferase compare
SMc00576 -1.0 -2.6 hypothetical protein compare
SMc02049 -1.0 -8.0 glycine dehydrogenase compare
SMa1118 -1.0 -1.4 HspC2 heat shock protein compare
SMc01207 -1.0 -1.5 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc02694 -1.0 -1.1 ATP-dependent Clp protease adaptor compare
SMc04000 -1.0 -0.7 hypothetical protein compare
SMc01124 -1.0 -3.3 PII uridylyl-transferase compare
SM_b20728 -1.0 -2.2 hypothetical protein compare
SM_b21454 -1.0 -1.6 hypothetical protein compare
SM_b20282 -1.0 -1.5 spermidine/putrescine ABC transporter permease compare
SMc02046 -1.0 -1.4 hypothetical protein compare
SMa5033 -0.9 -1.0 hypothetical protein compare
SMc02047 -0.9 -2.8 glycine cleavage system aminomethyltransferase T compare
SMc00080 -0.9 -2.4 hypothetical protein compare
SMc00072 -0.9 -1.3 peroxiredoxin protein compare
SMc00241 -0.9 -1.8 transcriptional regulator compare
SMc00605 -0.9 -1.6 hypothetical protein compare
SMc01114 -0.9 -3.5 phoH-like protein compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source Protocatechuic Acid in Sinorhizobium meliloti 1021

For carbon source Protocatechuic Acid across organisms