Experiment set9IT080 for Sinorhizobium meliloti 1021

Compare to:

Protocatechuic Acid carbon source

200 most important genes:

  gene name fitness t score description  
SMc00236 -7.8 -5.4 Indole-3-glycerol phosphate synthase compare
SMc02766 -7.8 -11.9 tryptophan synthase subunit beta compare
SMc01494 -7.3 -10.0 phosphoserine phosphatase compare
SMc02767 -7.3 -7.1 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02899 -7.1 -9.8 prephenate dehydratase compare
SMc00235 -7.1 -4.9 anthranilate phosphoribosyltransferase compare
SMc01054 -6.9 -4.8 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04045 -6.9 -4.8 dihydroxy-acid dehydratase compare
SMc02569 -6.7 -4.6 imidazole glycerol phosphate synthase subunit HisF compare
SMc02765 -6.5 -15.2 tryptophan synthase subunit alpha compare
SMc01843 -6.4 -9.8 5,10-methylenetetrahydrofolate reductase compare
SMc00640 -6.3 -4.4 phosphoserine aminotransferase compare
SMc02838 -6.3 -6.1 phosphoglyceromutase compare
SMc00711 -6.2 -4.3 cyclohexadienyl dehydrogenase compare
SMa1635 -6.2 -2.3 hypothetical protein compare
SMc04026 -6.1 -8.4 glutamate synthase compare
SMc02717 -6.1 -10.1 2-isopropylmalate synthase compare
SMc04028 -5.9 -11.4 glutamate synthase compare
SMc00494 -5.9 -2.2 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00918 -5.9 -7.0 ATP phosphoribosyltransferase regulatory subunit compare
SMc00293 -5.7 -11.7 homoserine dehydrogenase compare
SMc02725 -5.6 -11.5 anthranilate synthase compare
SMc02572 -5.6 -4.1 imidazole glycerol phosphate synthase subunit HisH compare
SM_b20587 -5.6 -10.7 CoA-transferase subunit A protein compare
SMc02123 -5.4 -4.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc00495 -5.3 -5.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02138 -5.3 -7.3 acetylornithine transaminase compare
SMc00917 -5.2 -4.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc01726 -5.2 -5.0 acetylglutamate kinase compare
SMc02562 -5.2 -7.9 phosphoenolpyruvate carboxykinase compare
SMc03112 -5.1 -16.1 B12-dependent methionine synthase compare
SMc03981 -5.1 -6.1 phosphoglycerate kinase compare
SMc01431 -5.1 -13.6 acetolactate synthase 3 catalytic subunit compare
SMc02137 -5.0 -3.5 ornithine carbamoyltransferase compare
SMc03797 -5.0 -11.7 homoserine O-succinyltransferase compare
SM_b20589 -5.0 -6.5 beta-ketoadipyl CoA thiolase conserved
SMc01004 -5.0 -8.3 phosphoribosyl-AMP cyclohydrolase compare
SMc01028 -4.9 -15.1 phosphopyruvate hydratase compare
SMc03979 -4.9 -3.4 glyceraldehyde-3-phosphate dehydrogenase compare
SMc02570 -4.8 -6.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02124 -4.8 -14.9 nitrite reductase compare
SMc00641 -4.8 -4.7 D-3-phosphoglycerate dehydrogenase compare
SMc04405 -4.8 -11.5 3-isopropylmalate dehydrogenase compare
SMc00614 -4.7 -8.0 phosphoribosylglycinamide formyltransferase compare
SM_b20588 -4.7 -7.8 CoA-transferase subunit B protein compare
SMc02217 -4.7 -7.1 O-succinylhomoserine sulfhydrylase compare
SMc03823 -4.6 -9.6 isopropylmalate isomerase large subunit compare
SMc03776 -4.3 -4.2 gamma-glutamyl kinase compare
SMc01801 -4.3 -3.6 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02707 -4.2 -5.2 hypothetical protein compare
SMc03777 -4.2 -7.9 gamma-glutamyl phosphate reductase compare
SMc00092 -4.2 -11.5 phosphoadenosine phosphosulfate reductase compare
SMc00493 -4.1 -5.9 phosphoribosylformylglycinamidine synthase I compare
SMc00131 -4.1 -12.6 transcriptional regulator compare
SMc00091 -4.1 -11.9 sulfate adenylyltransferase compare
SMc00615 -4.0 -8.8 phosphoribosylaminoimidazole synthetase compare
SMc00993 -4.0 -12.0 phosphoribosylamine--glycine ligase compare
SMc00090 -4.0 -10.3 sulfate adenylyltransferase compare
SMc04088 -4.0 -10.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc04002 -3.9 -6.5 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00414 -3.8 -9.4 hypothetical protein compare
SM_b21176 -3.7 -6.2 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00488 -3.7 -15.8 phosphoribosylformylglycinamidine synthase II compare
SMc03795 -3.7 -1.9 isopropylmalate isomerase small subunit compare
SMc04391 -3.7 -3.1 3-ketoacyl-ACP reductase compare
SMc02755 -3.6 -5.5 S-adenosyl-L-homocysteine hydrolase compare
SMc02165 -3.5 -7.1 orotate phosphoribosyltransferase compare
SMc02245 -3.5 -4.3 dihydroorotate dehydrogenase 2 compare
SMc02307 -3.5 -7.4 histidinol dehydrogenase compare
SMc01770 -3.5 -1.5 serine hydroxymethyltransferase compare
SMc02975 -3.5 -9.9 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc02166 -3.5 -9.2 dihydroorotase compare
SMc01360 -3.4 -2.3 aspartate carbamoyltransferase catalytic subunit compare
SMc00554 -3.3 -9.3 amidophosphoribosyltransferase compare
SMc01881 -3.3 -2.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03974 -3.2 -3.7 hypothetical protein compare
SMc00296 -3.2 -10.0 POLY3-hydroxybutyrate polymerase compare
SMc00412 -3.2 -4.8 orotidine 5'-phosphate decarboxylase compare
SMc01053 -3.1 -5.2 siroheme synthase compare
SMc03100 -3.1 -1.9 hypothetical protein compare
SM_b20579 -3.1 -7.2 beta-ketoadipate enol-lactone hydrolase conserved
SMc01206 -3.1 -1.5 queuine tRNA-ribosyltransferase compare
SMc02246 -3.0 -1.1 hypothetical protein compare
SMc03069 -3.0 -2.0 6-phosphogluconolactonase compare
SM_b21177 -2.9 -7.1 phosphate uptake ABC transporter ATP-binding protein compare
SMc01578 -2.9 -10.4 aspartate aminotransferase compare
SMc00294 -2.9 -10.0 aminotransferase compare
SMc02640 -2.8 -5.0 UDP-glucuronic acid epimerase compare
SMc04346 -2.8 -5.0 ketol-acid reductoisomerase compare
SMc00017 -2.7 -2.0 homoserine kinase compare
SM_b20577 -2.7 -5.9 protocatechuate 3,4-dioxygenase subunit beta conserved
SMc01430 -2.6 -5.0 acetolactate synthase 3 regulatory subunit compare
SMc02858 -2.4 -0.9 chaperone protein DnaJ compare
SMc00580 -2.4 -2.3 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc02695 -2.4 -6.0 GTP-dependent nucleic acid-binding protein EngD compare
SM_b21175 -2.3 -5.1 phosphate uptake ABC transporter permease compare
SMc03229 -2.3 -2.0 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00876 -2.3 -4.0 ATP-binding MRP protein compare
SMc01361 -2.2 -2.1 dihydroorotase compare
SMc04001 -2.2 -1.4 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02641 -2.2 -2.1 UDP-glucose 6-dehydrogenase compare
SM_b20955 -2.1 -2.9 endo-beta-1,3-1,4-glycanase compare
SMc01472 -2.1 -1.3 50S ribosomal protein L11 methyltransferase compare
SM_b21174 -2.0 -5.1 phosphate uptake ABC transporter permease compare
SMc01880 -2.0 -1.3 pantoate--beta-alanine ligase compare
SMc02115 -2.0 -0.7 hypothetical protein compare
SMc00481 -1.9 -12.3 hypothetical protein compare
SMc03978 -1.9 -1.3 transketolase compare
SMc01842 -1.9 -2.3 methyltransferase transcription regulator protein compare
SM_b20942 -1.8 -4.9 UDP glucose 4-epimerase compare
SMc01183 -1.8 -0.8 LexA repressor compare
SMc00010 -1.7 -1.2 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc01852 -1.7 -8.2 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc01220 -1.7 -4.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc02574 -1.7 -2.9 imidazoleglycerol-phosphate dehydratase compare
SM_b20576 -1.6 -5.2 protocatechuate 3,4-dioxygenase subunit alpha conserved
SMa1570 -1.6 -1.7 PilA2 pilus assembly protein compare
SM_b20578 -1.6 -2.6 gamma carboxymuconolactone decarboxylase compare
SMc02983 -1.6 -5.8 ornithine, DAP, or arginine decarboxylase compare
SMc02685 -1.5 -2.5 hypothetical protein compare
SMc02407 -1.5 -5.0 hypothetical protein compare
SMc00349 -1.5 -6.5 GTP-binding protein LepA compare
SM_b20586 -1.5 -2.3 IclR family transcriptional regulator compare
SMc02812 -1.5 -2.2 hypothetical protein compare
SMc02724 -1.5 -2.8 hypothetical protein compare
SMc00948 -1.4 -6.6 glutamine synthetase compare
SM_b21102 -1.4 -8.7 transcriptional regulator compare
SM_b20307 -1.4 -1.1 dihydroxyacetone kinase compare
SMc00726 -1.4 -0.7 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc03899 -1.4 -1.0 hypothetical protein compare
SMc00073 -1.3 -1.2 hypothetical protein compare
SMc02121 -1.3 -1.4 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc02095 -1.3 -6.6 hypothetical protein compare
SM_b21000 -1.3 -6.6 transporter compare
SMc00405 -1.3 -5.9 hypothetical protein compare
SMc02048 -1.3 -5.0 glycine cleavage system protein H compare
SMc02365 -1.2 -4.8 protease precursor protein compare
SMc00404 -1.2 -1.1 hypothetical protein compare
SMc02145 -1.2 -0.6 signal peptide protein compare
SMc00982 -1.2 -3.6 dioxygenase compare
SMc02833 -1.2 -0.8 penicillin-insensitive murein endopeptidase compare
SM_b20563 -1.2 -2.0 hypothetical protein compare
SMc00009 -1.2 -4.1 cytochrome C oxidase subunit II protein compare
SMa5015 -1.2 -1.9 hypothetical protein compare
SMc00087 -1.2 -5.9 hydrolase compare
SMc02112 -1.1 -3.7 hypothetical protein compare
SMc02850 -1.1 -1.3 DNA polymerase I compare
SMc03839 -1.1 -1.7 hypothetical protein compare
SMc04330 -1.1 -1.4 trimethylamine methyltransferase compare
SMc02403 -1.1 -7.0 murein transglycosylase compare
SMc02867 -1.1 -1.8 multidrug-efflux system transmembrane protein compare
SMc01579 -1.1 -1.2 hypothetical protein compare
SMc00302 -1.1 -1.1 hypothetical protein compare
SM_b20293 -1.1 -1.1 hypothetical protein compare
SMc00815 -1.1 -0.6 inosine 5'-monophosphate dehydrogenase compare
SM_b21569 -1.1 -1.6 transcriptional regulator compare
SMc01505 -1.0 -1.4 hypothetical protein compare
SMc01124 -1.0 -4.0 PII uridylyl-transferase compare
SMc01114 -1.0 -2.6 phoH-like protein compare
SMc02659 -1.0 -1.5 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc03878 -1.0 -1.6 acetoacetyl-CoA reductase compare
SMc02229 -1.0 -7.0 acyl-CoA dehydrogenase compare
SMc00450 -1.0 -1.0 protoheme IX farnesyltransferase compare
SMc02778 -1.0 -0.8 hydroxyacid aldolase compare
SMc00619 -1.0 -0.8 hypothetical protein compare
SMc02055 -1.0 -1.5 phytoene synthase compare
SMc02050 -1.0 -2.3 trigger factor compare
SMc03780 -0.9 -2.6 hypothetical protein compare
SMc01441 -0.9 -2.9 membrane bound protease compare
SMc04000 -0.9 -0.7 hypothetical protein compare
SM_b22005 -0.9 -1.0 hypothetical protein compare
SMa1779 -0.9 -1.6 hypothetical protein compare
SMc02714 -0.9 -1.0 hypothetical protein compare
SMc03763 -0.9 -0.8 cytosine-specific methyltransferase compare
SMa0674 -0.9 -1.3 hypothetical protein compare
SMc00705 -0.9 -4.5 signal peptide protein compare
SMa1036 -0.9 -4.0 hypothetical protein compare
SMc03279 -0.9 -1.5 transposase number 2 for insertion sequence ISRM28 compare
SMc02228 -0.9 -3.9 acetyl-CoA acetyltransferase compare
SMc01164 -0.9 -3.9 hypothetical protein compare
SMc04094 -0.9 -1.8 hypothetical protein compare
SMc02861 -0.9 -1.2 phosphate transporter compare
SMc00025 -0.9 -3.4 pyruvate phosphate dikinase compare
SMc02049 -0.9 -6.3 glycine dehydrogenase compare
SMa1625 -0.9 -2.0 LysR family transcriptional regulator compare
SMc02141 -0.9 -1.3 phosphate transporter PhoU compare
SM_b20690 -0.9 -1.4 hypothetical protein compare
SMc01916 -0.8 -1.4 signal peptide protein compare
SMc01877 -0.8 -2.4 DNA repair protein compare
SMc00569 -0.8 -1.7 hypothetical protein compare
SMc02677 -0.8 -2.6 pyrroline-5-carboxylate reductase compare
SMc01440 -0.8 -2.4 hydrolase serine protease transmembrane protein compare
SMc01845 -0.8 -0.8 transglycosylase transmembrane protein compare
SM_b21487 -0.8 -4.7 cytochrome o ubiquinol oxidase subunit II compare
SM_b21372 -0.8 -5.5 LacI family transcriptional regulator compare
SM_b21085 -0.8 -2.7 hypothetical protein compare
SM_b20580 -0.8 -2.1 LysR family transcriptional regulator compare
SMc00727 -0.8 -4.2 3-hydroxybutyryl-CoA dehydrogenase compare
SMc00556 -0.8 -2.8 DNA repair protein RadA compare
SMc04085 -0.8 -2.5 hypothetical protein compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source Protocatechuic Acid in Sinorhizobium meliloti 1021

For carbon source Protocatechuic Acid across organisms