Experiment set9IT076 for Sinorhizobium meliloti 1021

Compare to:

L-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
SMc02899 -6.4 -11.5 prephenate dehydratase compare
SMc02767 -6.3 -10.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc01494 -5.9 -13.9 phosphoserine phosphatase compare
SMc03981 -5.4 -5.3 phosphoglycerate kinase compare
SMc02766 -5.3 -16.7 tryptophan synthase subunit beta compare
SMc00917 -5.1 -5.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc03979 -5.0 -3.4 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00235 -5.0 -8.9 anthranilate phosphoribosyltransferase compare
SMc04045 -5.0 -10.1 dihydroxy-acid dehydratase compare
SMc02838 -4.9 -4.8 phosphoglyceromutase compare
SMc00640 -4.9 -9.3 phosphoserine aminotransferase compare
SMc00918 -4.8 -8.2 ATP phosphoribosyltransferase regulatory subunit compare
SMc04405 -4.8 -10.7 3-isopropylmalate dehydrogenase compare
SMc03112 -4.8 -19.0 B12-dependent methionine synthase compare
SMc02765 -4.8 -14.0 tryptophan synthase subunit alpha compare
SMc04028 -4.7 -19.3 glutamate synthase compare
SMc02562 -4.6 -8.3 phosphoenolpyruvate carboxykinase compare
SMc01843 -4.6 -12.6 5,10-methylenetetrahydrofolate reductase compare
SMc00131 -4.5 -14.9 transcriptional regulator compare
SMc04001 -4.5 -1.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02725 -4.4 -13.7 anthranilate synthase compare
SMc00615 -4.4 -9.7 phosphoribosylaminoimidazole synthetase compare
SMc01004 -4.4 -12.8 phosphoribosyl-AMP cyclohydrolase compare
SMc03823 -4.3 -12.2 isopropylmalate isomerase large subunit compare
SMc01028 -4.3 -15.0 phosphopyruvate hydratase compare
SMc02137 -4.3 -4.1 ornithine carbamoyltransferase compare
SMc01431 -4.3 -15.5 acetolactate synthase 3 catalytic subunit compare
SMc00293 -4.3 -9.8 homoserine dehydrogenase compare
SMc02717 -4.2 -16.1 2-isopropylmalate synthase compare
SMc02570 -4.1 -8.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03797 -4.1 -11.9 homoserine O-succinyltransferase compare
SMc03777 -4.0 -8.6 gamma-glutamyl phosphate reductase compare
SMc02217 -4.0 -7.8 O-succinylhomoserine sulfhydrylase compare
SMc04088 -3.9 -10.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00493 -3.9 -5.6 phosphoribosylformylglycinamidine synthase I compare
SMc00236 -3.9 -4.4 Indole-3-glycerol phosphate synthase compare
SMc03776 -3.8 -4.5 gamma-glutamyl kinase compare
SMc00488 -3.8 -16.7 phosphoribosylformylglycinamidine synthase II compare
SMc02165 -3.7 -7.5 orotate phosphoribosyltransferase compare
SMc03895 -3.7 -16.5 pyruvate carboxylase compare
SMc04002 -3.7 -5.7 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02569 -3.7 -3.9 imidazole glycerol phosphate synthase subunit HisF compare
SMc01801 -3.7 -2.3 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMa1635 -3.6 -2.9 hypothetical protein compare
SMc00993 -3.6 -12.2 phosphoribosylamine--glycine ligase compare
SMc00711 -3.5 -3.1 cyclohexadienyl dehydrogenase compare
SMc04026 -3.5 -8.7 glutamate synthase compare
SMc01770 -3.5 -1.6 serine hydroxymethyltransferase compare
SMc00017 -3.4 -1.8 homoserine kinase compare
SMc00554 -3.4 -9.7 amidophosphoribosyltransferase compare
SMc02245 -3.3 -5.9 dihydroorotate dehydrogenase 2 compare
SMc01726 -3.3 -8.3 acetylglutamate kinase compare
SMc00412 -3.2 -5.3 orotidine 5'-phosphate decarboxylase compare
SMc02166 -3.2 -9.9 dihydroorotase compare
SMc03100 -3.2 -2.1 hypothetical protein compare
SMc02753 -3.2 -1.2 PTS system transporter subunit IIA compare
SMc00614 -3.1 -9.1 phosphoribosylglycinamide formyltransferase compare
SMc00495 -3.0 -4.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04346 -2.9 -6.2 ketol-acid reductoisomerase compare
SMc00555 -2.9 -1.9 colicin V production transmembrane protein compare
SMc00641 -2.9 -4.7 D-3-phosphoglycerate dehydrogenase compare
SMc02510 -2.8 -1.1 ferric uptake regulation protein compare
SMc03974 -2.7 -5.6 hypothetical protein compare
SMc02123 -2.7 -5.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMa1765 -2.6 -1.6 hypothetical protein compare
SMc00295 -2.6 -1.4 hypothetical protein compare
SMc03795 -2.6 -2.4 isopropylmalate isomerase small subunit compare
SMc02232 -2.6 -2.8 hypothetical protein compare
SMc01361 -2.5 -1.7 dihydroorotase compare
SMc01360 -2.5 -2.9 aspartate carbamoyltransferase catalytic subunit compare
SMc01951 -2.5 -7.7 high-affinity branched-chain amino acid ABC transporter permease conserved
SMc02755 -2.5 -5.6 S-adenosyl-L-homocysteine hydrolase compare
SMc02138 -2.4 -5.2 acetylornithine transaminase compare
SMc02572 -2.4 -2.5 imidazole glycerol phosphate synthase subunit HisH compare
SMc02172 -2.4 -8.9 transcriptional regulator compare
SMc00090 -2.4 -7.8 sulfate adenylyltransferase compare
SMc00092 -2.4 -9.3 phosphoadenosine phosphosulfate reductase compare
SMc03069 -2.4 -2.6 6-phosphogluconolactonase compare
SMc00494 -2.4 -2.4 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02707 -2.4 -3.7 hypothetical protein compare
SMc01054 -2.3 -3.0 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02124 -2.3 -11.0 nitrite reductase compare
SMc00982 -2.2 -6.2 dioxygenase compare
SMc02055 -2.2 -2.3 phytoene synthase compare
SMc01120 -2.1 -3.9 hypothetical protein compare
SMc01881 -2.1 -2.4 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc02640 -2.0 -4.4 UDP-glucuronic acid epimerase compare
SMc00091 -2.0 -7.4 sulfate adenylyltransferase compare
SMc01950 -2.0 -12.4 high-affinity branched-chain amino acid ABC transporter permease conserved
SM_b20307 -2.0 -1.5 dihydroxyacetone kinase compare
SMc02641 -1.9 -2.2 UDP-glucose 6-dehydrogenase compare
SMc00414 -1.9 -10.1 hypothetical protein compare
SMc03229 -1.9 -1.5 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SM_b21176 -1.9 -4.7 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02683 -1.9 -2.5 hypothetical protein compare
SMc02975 -1.9 -7.2 phosphoenolpyruvate carboxykinase regulator transcription regulator protein compare
SMc02308 -1.9 -3.5 hypothetical protein compare
SMc00450 -1.8 -1.2 protoheme IX farnesyltransferase compare
SMc01053 -1.8 -5.5 siroheme synthase compare
SMc04260 -1.8 -9.8 transcriptional regulator compare
SMc03978 -1.8 -1.7 transketolase compare
SMc01579 -1.8 -1.8 hypothetical protein compare
SMc00859 -1.8 -2.2 hypothetical protein compare
SMc00876 -1.8 -3.5 ATP-binding MRP protein compare
SMc00427 -1.8 -1.6 peptide chain release factor RF-3 protein compare
SMc00187 -1.7 -2.6 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc02112 -1.7 -7.2 hypothetical protein compare
SMc02724 -1.7 -1.8 hypothetical protein compare
SMa2020 -1.7 -6.0 Transcriptional regulator compare
SMc02119 -1.7 -9.7 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 1 (from data) conserved
SMc03008 -1.7 -1.4 chemotaxis protein compare
SMc01916 -1.6 -2.2 signal peptide protein compare
SMc02121 -1.6 -1.6 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc01207 -1.6 -2.0 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SM_b21598 -1.6 -6.2 transcriptional regulator compare
SMa1442 -1.6 -3.9 GntR family transcriptional regulator compare
SMc02844 -1.5 -1.8 transcriptional regulator compare
SMc02058 -1.5 -2.8 YAJC protein compare
SM_b20948 -1.5 -1.6 glucosyltransferase compare
SMc02435 -1.5 -1.0 methyltransferase compare
SMc02850 -1.5 -1.4 DNA polymerase I compare
SMc01024 -1.5 -1.4 preprotein translocase subunit SecG compare
SMc01949 -1.4 -3.7 high-affinity branched-chain amino acid ABC transporter ATP-binding protein conserved
SMc00492 -1.4 -0.7 hypothetical protein compare
SMc00353 -1.4 -1.7 transmembrane protein compare
SMc02120 -1.3 -5.1 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, permease component 2 (from data) conserved
SMc02280 -1.3 -1.2 hypothetical protein compare
SMc01933 -1.3 -1.5 hypothetical protein compare
SMc01948 -1.3 -3.9 high-affinity branched-chain amino acid ABC transporter ATP-binding protein compare
SMc02228 -1.3 -4.7 acetyl-CoA acetyltransferase compare
SMc01164 -1.3 -5.7 hypothetical protein compare
SMc01495 -1.3 -2.4 transcriptional regulator compare
SMc01947 -1.3 -4.3 hypothetical protein compare
SMc00987 -1.2 -1.8 hypothetical protein compare
SMc01709 -1.2 -2.1 signal peptide protein compare
SMc00012 -1.2 -1.1 cytochrome C oxidase assembly protein compare
SMc03850 -1.2 -0.6 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc01206 -1.2 -1.3 queuine tRNA-ribosyltransferase compare
SM_b20509 -1.2 -2.9 transcriptional regulator compare
SM_b20312 -1.2 -5.9 dihydroxyacetone kinase compare
SM_b21591 -1.2 -1.4 GntR family transcriptional regulator compare
SMc01880 -1.2 -1.3 pantoate--beta-alanine ligase compare
SMc00802 -1.2 -1.0 hypothetical protein compare
SMc02460 -1.2 -5.9 hypothetical protein compare
SMc02118 -1.2 -4.7 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component (from data) conserved
SMc00356 -1.2 -3.5 lysyl-tRNA synthetase compare
SMa2289 -1.2 -1.4 hypothetical protein compare
SM_b21372 -1.2 -6.7 LacI family transcriptional regulator compare
SMc01220 -1.2 -3.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc00404 -1.1 -1.1 hypothetical protein compare
SMc02227 -1.1 -2.5 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02858 -1.1 -0.6 chaperone protein DnaJ compare
SMc00815 -1.1 -0.7 inosine 5'-monophosphate dehydrogenase compare
SM_b21102 -1.1 -5.1 transcriptional regulator compare
SM_b20921 -1.1 -2.3 hypothetical protein compare
SMc02434 -1.1 -1.9 hypothetical protein compare
SMa1365 -1.1 -1.0 ATP-binding protein compare
SMc00712 -1.1 -0.8 hypothetical protein compare
SMc03093 -1.1 -2.3 hypothetical protein compare
SMc00010 -1.1 -1.0 cytochrome C oxidase polypeptide I transmembrane protein compare
SMa0933 -1.0 -2.0 TraC conjugal transfer protein compare
SMc01169 -1.0 -5.8 alanine dehydrogenase oxidoreductase conserved
SMc03258 -1.0 -5.4 transcriptional regulator compare
SMc02897 -1.0 -1.5 cytochrome C transmembrane protein compare
SM_b21464 -1.0 -4.5 GntR family transcriptional regulator compare
SM_b21374 -1.0 -2.1 tagatose kinase (EC 2.7.1.101) (from data) compare
SMc04000 -1.0 -0.8 hypothetical protein compare
SMc02978 -0.9 -2.8 hypothetical protein compare
SM_b21177 -0.9 -4.7 phosphate uptake ABC transporter ATP-binding protein compare
SMc00981 -0.9 -4.1 ferredoxin protein compare
SMc02246 -0.9 -0.6 hypothetical protein compare
SMa0211 -0.9 -0.9 hypothetical protein compare
SMc02385 -0.9 -1.7 hypothetical protein compare
SMc00709 -0.9 -2.1 hypothetical protein compare
SMc02425 -0.9 -1.5 transcriptional regulator compare
SMa0078 -0.9 -4.1 LacI family transcriptional regulator compare
SMc03072 -0.9 -1.7 hypothetical protein compare
SM_b21687 -0.9 -1.6 hypothetical protein compare
SMc01168 -0.9 -5.5 transcriptional regulator compare
SMc02229 -0.9 -5.0 acyl-CoA dehydrogenase compare
SM_b20624 -0.9 -4.1 methylthioribose-1-phosphate isomerase compare
SMc01440 -0.9 -3.3 hydrolase serine protease transmembrane protein compare
SMc00188 -0.9 -3.8 cytochrome B transmembrane protein compare
SMc02143 -0.9 -1.9 phosphate ABC transporter permease compare
SMc01430 -0.9 -4.1 acetolactate synthase 3 regulatory subunit compare
SMc00667 -0.9 -1.2 hypothetical protein compare
SMc02247 -0.9 -0.9 signal peptide protein compare
SMa1658 -0.9 -2.0 hypothetical protein compare
SMa0222 -0.9 -1.9 GntR family transcriptional regulator compare
SMc02906 -0.9 -0.7 hypothetical protein compare
SMc00914 -0.9 -1.5 oxidoreductase compare
SM_b20392 -0.9 -2.8 transcriptional regulator NanR compare
SM_b21174 -0.9 -2.6 phosphate uptake ABC transporter permease compare
SMc01368 -0.8 -3.0 transport transmembrane protein compare
SM_b20324 -0.8 -3.8 ThuR, regulatory protein for trehalosemaltose transport system compare
SMc02050 -0.8 -2.4 trigger factor compare
SMa0874 -0.8 -2.6 NodN dehydratase compare
SMc01454 -0.8 -4.8 hypothetical protein compare
SM_b21211 -0.8 -5.9 hypothetical protein compare
SMa1697 -0.8 -1.6 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source L-Alanine in Sinorhizobium meliloti 1021

For carbon source L-Alanine across organisms