Experiment set9IT075 for Sinorhizobium meliloti 1021

Compare to:

5-Aminovaleric acid carbon source

200 most important genes:

  gene name fitness t score description  
SMc02838 -7.3 -7.1 phosphoglyceromutase compare
SMc01843 -6.5 -11.8 5,10-methylenetetrahydrofolate reductase compare
SMc02899 -6.5 -10.0 prephenate dehydratase compare
SMa1635 -6.3 -2.2 hypothetical protein compare
SMc03981 -6.1 -5.9 phosphoglycerate kinase compare
SMc01801 -5.9 -3.6 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01726 -5.8 -6.7 acetylglutamate kinase compare
SMc00917 -5.8 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc04045 -5.7 -9.6 dihydroxy-acid dehydratase compare
SMc00236 -5.7 -5.8 Indole-3-glycerol phosphate synthase compare
SMc00768 -5.6 -10.1 isocitrate lyase compare
SMc01028 -5.6 -14.5 phosphopyruvate hydratase compare
SMc01004 -5.6 -13.0 phosphoribosyl-AMP cyclohydrolase compare
SMc00918 -5.5 -9.9 ATP phosphoribosyltransferase regulatory subunit compare
SMc02570 -5.5 -6.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc03879 -5.4 -6.5 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (from data) compare
SMc02766 -5.3 -16.4 tryptophan synthase subunit beta compare
SMc02047 -5.3 -8.8 glycine cleavage system aminomethyltransferase T compare
SMc02137 -5.2 -3.6 ornithine carbamoyltransferase compare
SMc00293 -5.2 -12.9 homoserine dehydrogenase compare
SMc02569 -5.1 -4.5 imidazole glycerol phosphate synthase subunit HisF compare
SMc03979 -5.1 -3.5 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00769 -5.0 -12.6 hypothetical protein compare
SMc00131 -5.0 -16.1 transcriptional regulator compare
SMc02725 -5.0 -12.6 anthranilate synthase compare
SMc00235 -5.0 -6.5 anthranilate phosphoribosyltransferase compare
SM_b21182 -5.0 -10.3 hypothetical protein compare
SMc04088 -5.0 -11.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02765 -4.9 -12.5 tryptophan synthase subunit alpha compare
SMc02717 -4.9 -16.0 2-isopropylmalate synthase compare
SMc04405 -4.9 -10.0 3-isopropylmalate dehydrogenase compare
SMc01494 -4.9 -15.5 phosphoserine phosphatase compare
SMc03112 -4.9 -17.8 B12-dependent methionine synthase compare
SMc02048 -4.8 -9.0 glycine cleavage system protein H compare
SMc01054 -4.8 -4.3 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc01431 -4.7 -15.9 acetolactate synthase 3 catalytic subunit compare
SMc02308 -4.7 -5.8 hypothetical protein compare
SMc00554 -4.7 -9.5 amidophosphoribosyltransferase compare
SMc04882 -4.7 -3.1 transcriptional regulator compare
SMc03823 -4.6 -12.7 isopropylmalate isomerase large subunit compare
SMc02767 -4.6 -9.4 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc03797 -4.6 -10.2 homoserine O-succinyltransferase compare
SMc03776 -4.6 -4.4 gamma-glutamyl kinase compare
SMc04001 -4.5 -1.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00488 -4.5 -15.9 phosphoribosylformylglycinamidine synthase II compare
SMc00494 -4.5 -2.2 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00640 -4.5 -10.8 phosphoserine aminotransferase compare
SMc00993 -4.4 -13.2 phosphoribosylamine--glycine ligase compare
SMc00025 -4.4 -8.4 pyruvate phosphate dikinase compare
SMc02123 -4.3 -4.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02049 -4.3 -19.2 glycine dehydrogenase compare
SMc02245 -4.3 -4.3 dihydroorotate dehydrogenase 2 compare
SMc00495 -4.3 -4.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03069 -4.3 -2.5 6-phosphogluconolactonase compare
SMc00615 -4.3 -8.3 phosphoribosylaminoimidazole synthetase compare
SMc02166 -4.2 -11.2 dihydroorotase compare
SMc00493 -3.9 -7.3 phosphoribosylformylglycinamidine synthase I compare
SMc02217 -3.9 -5.2 O-succinylhomoserine sulfhydrylase compare
SMc02562 -3.9 -9.5 phosphoenolpyruvate carboxykinase compare
SMc00092 -3.9 -11.1 phosphoadenosine phosphosulfate reductase compare
SM_b21181 -3.9 -6.8 glutaryl-CoA dehydrogenase compare
SMc00614 -3.8 -5.9 phosphoribosylglycinamide formyltransferase compare
SMc04002 -3.7 -5.6 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02055 -3.7 -2.5 phytoene synthase compare
SMc02124 -3.7 -12.2 nitrite reductase compare
SMc02755 -3.6 -5.9 S-adenosyl-L-homocysteine hydrolase compare
SMc00017 -3.5 -1.7 homoserine kinase compare
SMc01360 -3.5 -2.4 aspartate carbamoyltransferase catalytic subunit compare
SMc00091 -3.4 -14.2 sulfate adenylyltransferase compare
SMc00187 -3.4 -3.7 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc04346 -3.4 -4.1 ketol-acid reductoisomerase compare
SMc02165 -3.4 -8.3 orotate phosphoribosyltransferase compare
SMc02572 -3.4 -2.4 imidazole glycerol phosphate synthase subunit HisH compare
SMc03777 -3.4 -9.3 gamma-glutamyl phosphate reductase compare
SMc01053 -3.3 -4.6 siroheme synthase compare
SMc02227 -3.2 -5.7 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02707 -3.2 -4.6 hypothetical protein compare
SMc00090 -3.1 -9.0 sulfate adenylyltransferase compare
SMc01206 -3.1 -1.5 queuine tRNA-ribosyltransferase compare
SMc03795 -3.1 -2.2 isopropylmalate isomerase small subunit compare
SMc00412 -3.1 -5.7 orotidine 5'-phosphate decarboxylase compare
SMc00726 -3.0 -1.0 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc02229 -2.8 -10.5 acyl-CoA dehydrogenase compare
SMc00711 -2.8 -3.1 cyclohexadienyl dehydrogenase compare
SMc01881 -2.7 -3.1 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03974 -2.7 -5.4 hypothetical protein compare
SMc02307 -2.7 -6.3 histidinol dehydrogenase compare
SMc01120 -2.6 -4.6 hypothetical protein compare
SMc00876 -2.6 -3.8 ATP-binding MRP protein compare
SMc01430 -2.4 -6.3 acetolactate synthase 3 regulatory subunit compare
SMc01124 -2.4 -7.6 PII uridylyl-transferase compare
SMc02228 -2.2 -5.3 acetyl-CoA acetyltransferase compare
SMa1053 -2.1 -1.9 hypothetical protein compare
SMc01880 -2.1 -1.4 pantoate--beta-alanine ligase compare
SMc01361 -2.1 -2.4 dihydroorotase compare
SMc02172 -2.0 -7.9 transcriptional regulator compare
SMc01950 -2.0 -10.7 high-affinity branched-chain amino acid ABC transporter permease compare
SMc03978 -2.0 -1.4 transketolase compare
SMc02138 -2.0 -4.9 acetylornithine transaminase compare
SMc02581 -2.0 -8.4 malate synthase G compare
SMc00450 -2.0 -1.3 protoheme IX farnesyltransferase compare
SMc00295 -1.9 -1.3 hypothetical protein compare
SMc01949 -1.9 -7.0 high-affinity branched-chain amino acid ABC transporter ATP-binding protein compare
SMc03279 -1.9 -2.2 transposase number 2 for insertion sequence ISRM28 compare
SMc02812 -1.9 -2.5 hypothetical protein compare
SMc00334 -1.9 -1.1 cytidylate kinase compare
SMc00189 -1.9 -3.4 cytochrome C1 protein compare
SMc00302 -1.8 -1.4 hypothetical protein compare
SM_b20086 -1.8 -2.1 hypothetical protein compare
SMc00414 -1.8 -9.9 hypothetical protein compare
SM_b20701 -1.8 -1.2 hypothetical protein compare
SMc03100 -1.8 -1.2 hypothetical protein compare
SMc02112 -1.8 -4.0 hypothetical protein compare
SMc02641 -1.8 -2.0 UDP-glucose 6-dehydrogenase compare
SMc01951 -1.7 -5.5 high-affinity branched-chain amino acid ABC transporter permease compare
SMc00087 -1.7 -6.4 hydrolase compare
SMc00641 -1.7 -2.8 D-3-phosphoglycerate dehydrogenase compare
SMa1365 -1.7 -1.5 ATP-binding protein compare
SMc01119 -1.6 -1.9 hypothetical protein compare
SMc00727 -1.6 -7.4 3-hydroxybutyryl-CoA dehydrogenase compare
SMc02844 -1.6 -1.7 transcriptional regulator compare
SMc01930 -1.6 -2.3 hypothetical protein compare
SMa2020 -1.6 -5.0 Transcriptional regulator compare
SMc02435 -1.6 -1.1 methyltransferase compare
SMc02451 -1.5 -1.3 hypothetical protein compare
SMc02850 -1.5 -1.4 DNA polymerase I compare
SMc00982 -1.5 -5.1 dioxygenase compare
SMa0789 -1.5 -2.4 GntR family transcriptional regulator compare
SMa1442 -1.5 -4.1 GntR family transcriptional regulator compare
SMc02260 -1.4 -1.3 ABC transporter ATP-binding protein compare
SMc02510 -1.4 -0.7 ferric uptake regulation protein compare
SMc02901 -1.4 -0.9 hypothetical protein compare
SM_b20509 -1.4 -3.1 transcriptional regulator compare
SMc02640 -1.4 -3.7 UDP-glucuronic acid epimerase compare
SM_b20290 -1.4 -3.9 transcriptional regulator compare
SMc02980 -1.3 -1.3 hypothetical protein compare
SMc02778 -1.3 -1.4 hydroxyacid aldolase compare
SMc03763 -1.3 -0.9 cytosine-specific methyltransferase compare
SM_b21501 -1.3 -3.1 hypothetical protein compare
SMc02145 -1.3 -0.6 signal peptide protein compare
SMc02121 -1.3 -1.4 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SM_b20294 -1.3 -0.9 transcriptional regulator NanR compare
SMc04028 -1.3 -8.7 glutamate synthase compare
SM_b20948 -1.3 -1.3 glucosyltransferase compare
SMc03850 -1.2 -0.6 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SM_b20250 -1.2 -4.6 hypothetical protein compare
SM_b20251 -1.2 -4.3 hypothetical protein compare
SMc04005 -1.2 -4.3 pyruvate kinase compare
SMc02521 -1.2 -2.5 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc04000 -1.2 -1.0 hypothetical protein compare
SMc01178 -1.2 -1.6 multidrug transmembrane resistance signal peptide protein compare
SMc01946 -1.2 -5.1 leucine-specific binding protein compare
SMc01471 -1.2 -1.8 cytochrome C oxidase assembly factor transmembrane protein compare
SM_b20312 -1.2 -5.2 dihydroxyacetone kinase compare
SM_b20249 -1.2 -3.8 myo-inositol-1-phosphate synthase compare
SMc00815 -1.1 -0.6 inosine 5'-monophosphate dehydrogenase compare
SM_b20258 -1.1 -2.1 transcriptional regulator compare
SMc00565 -1.1 -1.2 50S ribosomal protein L9 compare
SMc00656 -1.1 -1.1 hypothetical protein compare
SMc01770 -1.1 -1.5 serine hydroxymethyltransferase compare
SMc02362 -1.1 -1.2 cytochrome c-type biogenesis protein CcmE compare
SM_b20148 -1.1 -2.0 transcriptional regulator compare
SMc04026 -1.1 -4.8 glutamate synthase compare
SMc02425 -1.1 -2.8 transcriptional regulator compare
SMc00760 -1.1 -2.0 recombinase A compare
SMc02858 -1.1 -0.5 chaperone protein DnaJ compare
SMc04003 -1.1 -1.0 50S ribosomal protein L36 compare
SMc02689 -1.1 -5.3 aldehyde dehydrogenase compare
SMc00010 -1.0 -1.1 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc01091 -1.0 -1.7 hypothetical protein compare
SM_b20555 -1.0 -3.1 hypothetical protein compare
SMa1658 -1.0 -1.6 hypothetical protein compare
SM_b20026 -1.0 -1.8 hypothetical protein compare
SMc01948 -1.0 -2.5 high-affinity branched-chain amino acid ABC transporter ATP-binding protein compare
SMc03855 -1.0 -1.9 hypothetical protein compare
SMc02246 -1.0 -0.6 hypothetical protein compare
SMc02685 -1.0 -2.2 hypothetical protein compare
SMa1770 -1.0 -0.9 hypothetical protein compare
SM_b21511 -1.0 -1.2 plasmid stability protein compare
SMc04085 -1.0 -2.1 hypothetical protein compare
SMc02141 -1.0 -1.4 phosphate transporter PhoU compare
SMc00619 -1.0 -0.8 hypothetical protein compare
SMc04348 -1.0 -0.9 transcriptional regulator compare
SMc03996 -1.0 -1.7 thiamine-phosphate pyrophosphorylase compare
SMc03312 -1.0 -1.6 transposase ISRM11/ISRM2011-2 compare
SMc01505 -0.9 -1.1 hypothetical protein compare
SMc04391 -0.9 -1.3 3-ketoacyl-ACP reductase compare
SMc00045 -0.9 -1.2 cytochrome C signal peptide protein compare
SMc03229 -0.9 -0.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03031 -0.9 -1.4 flagellar basal body P-ring biosynthesis protein FlgA compare
SMc02659 -0.9 -1.9 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc02250 -0.9 -2.1 large-conductance mechanosensitive channel compare
SM_b21443 -0.9 -2.6 hypothetical protein compare
SMc01947 -0.9 -2.3 hypothetical protein compare
SMa0797 -0.9 -1.7 hypothetical protein compare
SMc03863 -0.9 -1.3 50S ribosomal protein L19 compare
SMc02225 -0.9 -2.6 hypothetical protein compare
SMc01220 -0.9 -2.6 lipopolysaccharide core biosynthesis glycosyl transferase compare
SM_b20313 -0.9 -2.6 glycerone kinase compare
SMa0513 -0.9 -2.1 gluconate 5-dehydrogenase compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source 5-Aminovaleric acid in Sinorhizobium meliloti 1021

For carbon source 5-Aminovaleric acid across organisms