Experiment set9IT069 for Sinorhizobium meliloti 1021

Compare to:

D-Mannose carbon source

200 most important genes:

  gene name fitness t score description  
SMc02572 -9.0 -5.9 imidazole glycerol phosphate synthase subunit HisH compare
SMc02123 -8.1 -3.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02766 -8.0 -11.0 tryptophan synthase subunit beta compare
SMc00236 -7.8 -5.4 Indole-3-glycerol phosphate synthase compare
SMc01494 -7.3 -10.0 phosphoserine phosphatase compare
SMc00495 -7.2 -4.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03797 -7.2 -7.0 homoserine O-succinyltransferase compare
SMc04045 -7.0 -4.8 dihydroxy-acid dehydratase compare
SMc01843 -6.9 -8.2 5,10-methylenetetrahydrofolate reductase compare
SMc02767 -6.9 -8.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02899 -6.9 -9.4 prephenate dehydratase compare
SMc02569 -6.8 -4.7 imidazole glycerol phosphate synthase subunit HisF compare
SMc00917 -6.8 -4.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02765 -6.7 -13.7 tryptophan synthase subunit alpha compare
SMc00235 -6.5 -6.3 anthranilate phosphoribosyltransferase compare
SMc00131 -6.5 -12.5 transcriptional regulator compare
SMc00993 -6.5 -6.3 phosphoribosylamine--glycine ligase compare
SMc00640 -6.4 -4.4 phosphoserine aminotransferase compare
SMc04405 -6.3 -7.5 3-isopropylmalate dehydrogenase compare
SMc01431 -6.3 -7.5 acetolactate synthase 3 catalytic subunit compare
SMc00615 -6.3 -13.4 phosphoribosylaminoimidazole synthetase compare
SMc00711 -6.2 -4.3 cyclohexadienyl dehydrogenase compare
SMc02725 -6.2 -11.1 anthranilate synthase compare
SMa1635 -6.2 -2.4 hypothetical protein compare
SMc04028 -6.1 -9.4 glutamate synthase compare
SMc01726 -6.1 -5.4 acetylglutamate kinase compare
SMc00614 -6.0 -7.2 phosphoribosylglycinamide formyltransferase compare
SMc03112 -6.0 -14.5 B12-dependent methionine synthase compare
SMc01054 -5.9 -5.7 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02978 -5.9 -4.1 hypothetical protein compare
SMc00494 -5.9 -2.3 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02717 -5.8 -13.0 2-isopropylmalate synthase compare
SMc00488 -5.8 -18.2 phosphoribosylformylglycinamidine synthase II compare
SMc01801 -5.8 -3.8 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc03895 -5.7 -14.8 pyruvate carboxylase compare
SMc04002 -5.7 -8.8 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03111 -5.7 -5.6 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc03823 -5.7 -12.7 isopropylmalate isomerase large subunit compare
SMc00090 -5.6 -9.4 sulfate adenylyltransferase compare
SMc02124 -5.6 -12.6 nitrite reductase compare
SMc03777 -5.5 -5.4 gamma-glutamyl phosphate reductase compare
SMc00493 -5.5 -6.5 phosphoribosylformylglycinamidine synthase I compare
SMc03109 -5.4 -9.1 Mannokinase (EC 2.7.1.7) (from data) conserved
SMc02570 -5.4 -6.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00293 -5.3 -12.3 homoserine dehydrogenase compare
SMc00918 -5.0 -9.8 ATP phosphoribosyltransferase regulatory subunit compare
SMc01004 -5.0 -8.3 phosphoribosyl-AMP cyclohydrolase compare
SMc00092 -5.0 -9.3 phosphoadenosine phosphosulfate reductase compare
SMc02217 -4.9 -6.8 O-succinylhomoserine sulfhydrylase compare
SM_b21177 -4.9 -9.3 phosphate uptake ABC transporter ATP-binding protein compare
SMc00412 -4.8 -3.3 orotidine 5'-phosphate decarboxylase compare
SMc04088 -4.7 -10.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02245 -4.7 -5.3 dihydroorotate dehydrogenase 2 compare
SMc00554 -4.7 -7.2 amidophosphoribosyltransferase compare
SMc00091 -4.6 -10.2 sulfate adenylyltransferase compare
SMc04001 -4.5 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc04026 -4.4 -7.4 glutamate synthase compare
SMc03776 -4.4 -4.3 gamma-glutamyl kinase compare
SMc03069 -4.2 -2.7 6-phosphogluconolactonase compare
SMc02166 -4.2 -10.8 dihydroorotase compare
SMc01053 -4.2 -5.4 siroheme synthase compare
SMc02574 -4.1 -5.6 imidazoleglycerol-phosphate dehydratase compare
SM_b21175 -4.1 -4.9 phosphate uptake ABC transporter permease compare
SMc02755 -4.1 -3.9 S-adenosyl-L-homocysteine hydrolase compare
SMc01430 -4.0 -7.8 acetolactate synthase 3 regulatory subunit compare
SMc03070 -3.9 -5.3 glucose-6-phosphate 1-dehydrogenase compare
SMc03979 -3.9 -3.7 glyceraldehyde-3-phosphate dehydrogenase compare
SM_b21176 -3.8 -5.8 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc02137 -3.8 -3.7 ornithine carbamoyltransferase compare
SMc03795 -3.8 -2.0 isopropylmalate isomerase small subunit compare
SMc02165 -3.8 -6.7 orotate phosphoribosyltransferase compare
SM_b21174 -3.6 -6.0 phosphate uptake ABC transporter permease compare
SMc02307 -3.6 -7.8 histidinol dehydrogenase compare
SMc01770 -3.5 -1.6 serine hydroxymethyltransferase compare
SMc00017 -3.5 -1.8 homoserine kinase compare
SMc02640 -3.4 -4.6 UDP-glucuronic acid epimerase compare
SMc04346 -3.4 -4.4 ketol-acid reductoisomerase compare
SMc01881 -3.4 -2.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03068 -3.4 -10.1 phosphogluconate dehydratase compare
SMc02707 -3.3 -5.6 hypothetical protein compare
SMc00294 -3.2 -9.3 aminotransferase compare
SMc00302 -3.2 -1.7 hypothetical protein compare
SMc02246 -3.1 -1.2 hypothetical protein compare
SMc00876 -3.1 -3.6 ATP-binding MRP protein compare
SMc02983 -3.1 -8.3 ornithine, DAP, or arginine decarboxylase compare
SMc01124 -3.0 -10.2 PII uridylyl-transferase compare
SMc02138 -2.9 -5.3 acetylornithine transaminase compare
SMc04005 -2.9 -7.7 pyruvate kinase compare
SMc03981 -2.9 -4.4 phosphoglycerate kinase compare
SMc01360 -2.9 -2.7 aspartate carbamoyltransferase catalytic subunit compare
SMc02641 -2.8 -1.9 UDP-glucose 6-dehydrogenase compare
SMc00882 -2.8 -5.4 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
SMc01578 -2.7 -9.5 aspartate aminotransferase compare
SMc00982 -2.6 -6.2 dioxygenase compare
SMc00641 -2.6 -3.5 D-3-phosphoglycerate dehydrogenase compare
SMc01361 -2.6 -1.8 dihydroorotase compare
SMc01028 -2.4 -11.2 phosphopyruvate hydratase compare
SMc04391 -2.4 -3.1 3-ketoacyl-ACP reductase compare
SMc00414 -2.1 -11.0 hypothetical protein compare
SMc02979 -2.1 -5.0 hypothetical protein compare
SMc01880 -2.1 -1.4 pantoate--beta-alanine ligase compare
SMc03978 -2.0 -1.4 transketolase compare
SMc03110 -2.0 -4.7 hypothetical protein compare
SMc03229 -1.9 -1.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03924 -1.9 -8.4 glycogen synthase compare
SMc00450 -1.9 -1.3 protoheme IX farnesyltransferase compare
SMc01842 -1.9 -2.2 methyltransferase transcription regulator protein compare
SMc01613 -1.9 -4.7 ribose-5-phosphate isomerase B compare
SMc01206 -1.9 -1.7 queuine tRNA-ribosyltransferase compare
SMc02838 -1.8 -4.6 phosphoglyceromutase compare
SMc02558 -1.8 -3.5 hypothetical protein compare
SMc02142 -1.8 -2.9 phosphate transporter ATP-binding protein compare
SMc01440 -1.7 -6.1 hydrolase serine protease transmembrane protein compare
SMc02112 -1.7 -6.5 hypothetical protein compare
SM_b20904 -1.6 -3.6 sugar uptake ABC transporter ATP-binding protein compare
SMc02909 -1.6 -1.8 transglycosylase transmembrane protein compare
SMc03153 -1.6 -3.4 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc00914 -1.6 -2.3 oxidoreductase compare
SMc00981 -1.6 -5.0 ferredoxin protein compare
SM_b20413 -1.6 -1.3 hypothetical protein compare
SMc02172 -1.6 -6.8 transcriptional regulator compare
SMc00187 -1.5 -2.2 ubiquinol-cytochrome C reductase iron-sulfur subunit protein compare
SMc02055 -1.5 -1.8 phytoene synthase compare
SMc00928 -1.5 -1.1 signal peptide protein compare
SMc02058 -1.4 -2.6 YAJC protein compare
SMc00726 -1.4 -0.7 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc04224 -1.4 -1.8 hypothetical protein compare
SMc02232 -1.4 -2.0 hypothetical protein compare
SMc01220 -1.4 -3.1 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMa1095 -1.4 -1.0 hypothetical protein compare
SM_b20902 -1.4 -7.4 sugar uptake ABC transporter substrate-binding protein precursor compare
SMa1765 -1.4 -1.4 hypothetical protein compare
SMc00073 -1.4 -1.3 hypothetical protein compare
SMc04404 -1.4 -1.5 amino acid efflux transmembrane protein compare
SM_b20994 -1.3 -4.2 hypothetical protein compare
SMc02724 -1.3 -2.7 hypothetical protein compare
SMc02844 -1.3 -1.3 transcriptional regulator compare
SMc00010 -1.3 -1.2 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc01207 -1.3 -1.8 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc01852 -1.3 -6.3 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc03072 -1.3 -2.1 hypothetical protein compare
SMc02145 -1.3 -0.7 signal peptide protein compare
SM_b20903 -1.2 -6.5 sugar uptake ABC transporter permease compare
SMc02451 -1.2 -1.4 hypothetical protein compare
SMa0905 -1.2 -1.4 hypothetical protein compare
SM_b20955 -1.2 -3.0 endo-beta-1,3-1,4-glycanase compare
SM_b20320 -1.2 -1.4 TRAP-type large permease component compare
SMc04348 -1.2 -1.4 transcriptional regulator compare
SMc03850 -1.2 -0.6 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc00295 -1.2 -0.9 hypothetical protein compare
SMc01845 -1.2 -1.2 transglycosylase transmembrane protein compare
SMc03890 -1.2 -3.9 transcriptional regulator compare
SMc00815 -1.2 -0.7 inosine 5'-monophosphate dehydrogenase compare
SM_b20616 -1.1 -2.1 thiamine biosynthesis oxidoreductase compare
SMc01858 -1.1 -1.2 S-adenosyl-methyltransferase MraW compare
SMc01441 -1.1 -3.3 membrane bound protease compare
SMc00859 -1.1 -1.6 hypothetical protein compare
SMc01505 -1.1 -1.5 hypothetical protein compare
SM_b20948 -1.1 -1.3 glucosyltransferase compare
SMc04245 -1.1 -6.9 high-affinity zinc uptake system ABC transporter protein compare
SM_b20324 -1.1 -5.6 ThuR, regulatory protein for trehalosemaltose transport system compare
SMc00053 -1.1 -0.5 monovalent cation/H+ antiporter subunit C compare
SMc04454 -1.1 -3.8 ABC transporter ATP-binding protein compare
SM_b21591 -1.1 -2.2 GntR family transcriptional regulator compare
SM_b20921 -1.1 -2.2 hypothetical protein compare
SMc00727 -1.1 -5.0 3-hydroxybutyryl-CoA dehydrogenase compare
SMc00013 -1.0 -0.9 cytochrome C oxidase subunit III transmembrane protein compare
SMc02812 -1.0 -1.8 hypothetical protein compare
SMc01540 -1.0 -2.6 hypothetical protein compare
SMc00622 -1.0 -4.1 ribonuclease D protein compare
SMc02434 -1.0 -2.1 hypothetical protein compare
SMc02250 -1.0 -2.1 large-conductance mechanosensitive channel compare
SM_b20042 -1.0 -3.2 hypothetical protein compare
SM_b21359 -1.0 -3.3 LysR family transcriptional regulator compare
SMc04243 -1.0 -4.6 high-affinity zinc uptake system membrane ABC transporter protein compare
SMc03763 -1.0 -0.9 cytosine-specific methyltransferase compare
SMa2215 -1.0 -1.5 GntR family transcriptional regulator compare
SMc01614 -1.0 -1.8 triosephosphate isomerase compare
SMc02048 -1.0 -4.0 glycine cleavage system protein H compare
SMc01724 -1.0 -2.2 hypothetical protein compare
SM_b21132 -0.9 -2.9 sulfate ABC transporter permease compare
SMc03876 -0.9 -2.4 HEAT shock-like protein compare
SMc00580 -0.9 -1.7 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc00579 -0.9 -2.0 dimethyladenosine transferase compare
SMc01342 -0.9 -2.5 hypothetical protein compare
SM_b21130 -0.9 -4.0 sulfate ABC transporter ATP-binding protein compare
SM_b20089 -0.9 -1.7 hypothetical protein compare
SMc00760 -0.9 -2.4 recombinase A compare
SMc03066 -0.9 -0.9 hypothetical protein compare
SMc01043 -0.9 -5.1 nitrogen assimilation regulatory protein compare
SM_b20314 -0.9 -4.6 glycerone kinase compare
SM_b20083 -0.9 -1.6 hypothetical protein compare
SMa0349 -0.9 -1.8 hypothetical protein compare
SM_b21108 -0.9 -3.0 L-fucose mutarotase (EC 5.1.3.29) (from data) compare
SMc00067 -0.9 -3.1 outer-membranne lipoprotein compare
SMc03801 -0.9 -1.7 thioredoxin protein compare
SMc01041 -0.9 -1.6 NIFR3-like protein compare
SMc02683 -0.9 -1.5 hypothetical protein compare
SM_b20773 -0.9 -2.3 GntR family transcriptional regulator compare
SMc02407 -0.9 -3.3 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source D-Mannose in Sinorhizobium meliloti 1021

For carbon source D-Mannose across organisms