Experiment set9IT061 for Sinorhizobium meliloti 1021

Compare to:

D-Mannitol carbon source

200 most important genes:

  gene name fitness t score description  
SMc02572 -9.1 -6.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc01494 -7.7 -9.2 phosphoserine phosphatase compare
SMc01726 -7.5 -5.2 acetylglutamate kinase compare
SMc02767 -7.4 -7.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00235 -7.3 -5.0 anthranilate phosphoribosyltransferase compare
SMc02766 -7.3 -17.6 tryptophan synthase subunit beta compare
SMc02899 -7.2 -8.6 prephenate dehydratase compare
SMc02570 -7.0 -4.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00917 -6.9 -4.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02765 -6.7 -12.6 tryptophan synthase subunit alpha compare
SMc00640 -6.5 -4.5 phosphoserine aminotransferase compare
SMc02245 -6.5 -4.5 dihydroorotate dehydrogenase 2 compare
SMc03797 -6.5 -10.0 homoserine O-succinyltransferase compare
SMc04002 -6.5 -9.9 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc04045 -6.5 -7.7 dihydroxy-acid dehydratase compare
SMc00711 -6.4 -4.4 cyclohexadienyl dehydrogenase compare
SMc02717 -6.3 -11.4 2-isopropylmalate synthase compare
SMc01843 -6.3 -12.7 5,10-methylenetetrahydrofolate reductase compare
SMa1635 -6.2 -2.4 hypothetical protein compare
SMc04405 -6.2 -9.5 3-isopropylmalate dehydrogenase compare
SMc00615 -6.1 -11.1 phosphoribosylaminoimidazole synthetase compare
SMc01054 -6.1 -5.1 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc04028 -6.1 -13.1 glutamate synthase compare
SMc00494 -6.1 -2.4 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00236 -6.0 -5.3 Indole-3-glycerol phosphate synthase compare
SMc02574 -6.0 -5.9 imidazoleglycerol-phosphate dehydratase compare
SMc00488 -6.0 -17.8 phosphoribosylformylglycinamidine synthase II compare
SMc03776 -6.0 -4.1 gamma-glutamyl kinase compare
SMc03112 -6.0 -16.0 B12-dependent methionine synthase compare
SMc00993 -6.0 -9.2 phosphoribosylamine--glycine ligase compare
SMc02569 -5.9 -5.7 imidazole glycerol phosphate synthase subunit HisF compare
SM_b21175 -5.8 -5.4 phosphate uptake ABC transporter permease compare
SMc01004 -5.7 -10.9 phosphoribosyl-AMP cyclohydrolase compare
SMc01431 -5.6 -12.0 acetolactate synthase 3 catalytic subunit compare
SMc02725 -5.6 -13.5 anthranilate synthase compare
SMc00131 -5.6 -16.5 transcriptional regulator compare
SMc00495 -5.6 -5.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03895 -5.6 -16.1 pyruvate carboxylase compare
SMc02217 -5.4 -6.4 O-succinylhomoserine sulfhydrylase compare
SMc00090 -5.4 -12.6 sulfate adenylyltransferase compare
SMc00918 -5.4 -10.4 ATP phosphoribosyltransferase regulatory subunit compare
SMc00614 -5.3 -8.1 phosphoribosylglycinamide formyltransferase compare
SMc04026 -5.3 -8.5 glutamate synthase compare
SMc02137 -5.3 -3.6 ornithine carbamoyltransferase compare
SMc00092 -5.2 -13.5 phosphoadenosine phosphosulfate reductase compare
SMc03823 -5.2 -12.1 isopropylmalate isomerase large subunit compare
SMc00091 -5.2 -11.1 sulfate adenylyltransferase compare
SMc02124 -5.1 -14.8 nitrite reductase compare
SMc04088 -5.1 -10.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00293 -5.1 -12.4 homoserine dehydrogenase compare
SMc02123 -5.0 -4.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc00412 -5.0 -3.4 orotidine 5'-phosphate decarboxylase compare
SMc00493 -4.9 -7.4 phosphoribosylformylglycinamidine synthase I compare
SMc00554 -4.8 -7.4 amidophosphoribosyltransferase compare
SMc01501 -4.8 -2.7 mannitol 2-dehydrogenase compare
SMc03777 -4.7 -7.9 gamma-glutamyl phosphate reductase compare
SMc03070 -4.7 -3.2 glucose-6-phosphate 1-dehydrogenase compare
SMc02164 -4.7 -4.2 fructokinase compare
SMc04001 -4.6 -1.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc03229 -4.5 -3.0 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SM_b21176 -4.5 -6.1 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00294 -4.4 -12.3 aminotransferase compare
SMc03069 -4.4 -2.8 6-phosphogluconolactonase compare
SMc01801 -4.4 -3.3 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SM_b21177 -4.3 -8.2 phosphate uptake ABC transporter ATP-binding protein compare
SMc02171 -4.3 -5.2 periplasmic binding ABC transporter protein compare
SMc02707 -4.2 -5.5 hypothetical protein compare
SMc03979 -4.1 -3.9 glyceraldehyde-3-phosphate dehydrogenase compare
SMc02307 -4.0 -9.1 histidinol dehydrogenase compare
SMc03068 -4.0 -9.4 phosphogluconate dehydratase compare
SMc02755 -4.0 -5.5 S-adenosyl-L-homocysteine hydrolase compare
SMc02165 -3.9 -7.0 orotate phosphoribosyltransferase compare
SMc02166 -3.9 -9.2 dihydroorotase compare
SMc01053 -3.8 -5.0 siroheme synthase compare
SM_b21174 -3.8 -4.7 phosphate uptake ABC transporter permease compare
SMc01497 -3.6 -8.2 sorbitol/mannitol transport inner membrane transmembrane protein conserved
SMc01770 -3.6 -1.6 serine hydroxymethyltransferase compare
SMc00017 -3.6 -1.8 homoserine kinase compare
SMc00876 -3.6 -2.5 ATP-binding MRP protein compare
SMc02138 -3.5 -7.8 acetylornithine transaminase compare
SMc01498 -3.4 -10.3 sorbitol/mannitol transport inner membrane protein conserved
SMc03981 -3.4 -4.2 phosphoglycerate kinase compare
SMc04346 -3.3 -4.4 ketol-acid reductoisomerase compare
SMc02246 -3.2 -1.2 hypothetical protein compare
SMc01206 -3.2 -1.6 queuine tRNA-ribosyltransferase compare
SMc03795 -3.2 -2.4 isopropylmalate isomerase small subunit compare
SMc00641 -3.2 -4.5 D-3-phosphoglycerate dehydrogenase compare
SMc01499 -3.1 -11.6 ATP-binding transport ABC transporter protein conserved
SMc01881 -3.1 -2.9 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00492 -3.1 -1.1 hypothetical protein compare
SMc01430 -2.9 -3.9 acetolactate synthase 3 regulatory subunit compare
SMc02169 -2.8 -2.4 ABC transporter ATP-binding protein compare
SMc02640 -2.8 -5.2 UDP-glucuronic acid epimerase compare
SMc02983 -2.7 -7.7 ornithine, DAP, or arginine decarboxylase compare
SMc01496 -2.6 -8.1 sorbitol-binding periplasmic protein conserved
SMc01500 -2.6 -3.2 sorbitol dehydrogenase compare
SMc03153 -2.5 -3.7 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc01360 -2.4 -3.1 aspartate carbamoyltransferase catalytic subunit compare
SMc01361 -2.4 -2.3 dihydroorotase compare
SMc02641 -2.3 -2.2 UDP-glucose 6-dehydrogenase compare
SMc03924 -2.2 -9.3 glycogen synthase compare
SMc01124 -2.2 -6.7 PII uridylyl-transferase compare
SMc01852 -2.2 -9.1 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc01578 -2.2 -8.4 aspartate aminotransferase compare
SMc01028 -2.1 -11.3 phosphopyruvate hydratase compare
SMc01939 -2.1 -1.7 urease subunit beta compare
SMc04330 -2.1 -2.3 trimethylamine methyltransferase compare
SMc03978 -2.1 -1.4 transketolase compare
SMc02838 -2.1 -8.2 phosphoglyceromutase compare
SMc02167 -2.0 -5.2 fructose transport system kinase compare
SMc01220 -2.0 -4.1 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc00334 -2.0 -1.2 cytidylate kinase compare
SMc02170 -1.9 -4.9 ABC transporter permease compare
SMc02434 -1.9 -3.3 hypothetical protein compare
SM_b20948 -1.9 -1.7 glucosyltransferase compare
SMc01880 -1.9 -1.7 pantoate--beta-alanine ligase compare
SMc01503 -1.8 -10.2 sugar kinase conserved
SMc01447 -1.7 -1.4 hypothetical protein compare
SMc01800 -1.7 -0.8 cytochrome C oxidase assembly transmembrane protein compare
SMc02407 -1.7 -7.0 hypothetical protein compare
SMc02280 -1.6 -2.0 hypothetical protein compare
SMc00726 -1.6 -0.8 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc01441 -1.6 -5.3 membrane bound protease compare
SMc00302 -1.5 -1.3 hypothetical protein compare
SMc00914 -1.5 -2.6 oxidoreductase compare
SMc01842 -1.5 -1.5 methyltransferase transcription regulator protein compare
SMc00856 -1.4 -1.2 hypothetical protein compare
SMc00012 -1.4 -1.2 cytochrome C oxidase assembly protein compare
SMc00414 -1.4 -8.3 hypothetical protein compare
SMc02145 -1.4 -0.7 signal peptide protein compare
SMc02102 -1.4 -2.8 hypothetical protein compare
SMc03763 -1.4 -0.9 cytosine-specific methyltransferase compare
SMc02724 -1.4 -2.9 hypothetical protein compare
SMc02894 -1.3 -1.7 hypothetical protein compare
SMc00053 -1.3 -0.6 monovalent cation/H+ antiporter subunit C compare
SMc03980 -1.2 -3.2 hypothetical protein compare
SMc01723 -1.2 -1.8 hypothetical protein compare
SMc00067 -1.2 -4.9 outer-membranne lipoprotein compare
SMc00982 -1.2 -4.2 dioxygenase compare
SMc00815 -1.2 -0.7 inosine 5'-monophosphate dehydrogenase compare
SMc02858 -1.2 -0.6 chaperone protein DnaJ compare
SMc01368 -1.2 -3.1 transport transmembrane protein compare
SMc02582 -1.2 -2.4 hypothetical protein compare
SMc02758 -1.2 -3.8 nucleotidyl transferase compare
SMc02753 -1.2 -0.7 PTS system transporter subunit IIA compare
SMc00981 -1.2 -5.2 ferredoxin protein compare
SMc01043 -1.1 -6.3 nitrogen assimilation regulatory protein compare
SM_b20330 -1.1 -4.5 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) compare
SMa2289 -1.1 -1.3 hypothetical protein compare
SMc02850 -1.1 -1.4 DNA polymerase I compare
SMc02052 -1.1 -1.0 hypothetical protein compare
SMc04000 -1.1 -0.8 hypothetical protein compare
SMc02683 -1.0 -1.6 hypothetical protein compare
SMc02050 -1.0 -2.5 trigger factor compare
SMc00579 -1.0 -2.6 dimethyladenosine transferase compare
SMc03279 -1.0 -1.2 transposase number 2 for insertion sequence ISRM28 compare
SMc01440 -1.0 -3.8 hydrolase serine protease transmembrane protein compare
SMc00361 -1.0 -1.8 hypothetical protein compare
SMc01097 -1.0 -3.0 hypothetical protein compare
SMc02695 -1.0 -3.8 GTP-dependent nucleic acid-binding protein EngD compare
SMc02719 -1.0 -1.0 transposase compare
SMc02365 -1.0 -4.1 protease precursor protein compare
SMc02232 -0.9 -1.8 hypothetical protein compare
SMc02451 -0.9 -0.8 hypothetical protein compare
SMc02058 -0.9 -2.3 YAJC protein compare
SMc02714 -0.9 -1.2 hypothetical protein compare
SM_b20323 -0.9 -0.9 transcriptional regulator compare
SMc00804 -0.9 -1.3 hypothetical protein compare
SMc00791 -0.9 -1.5 hypothetical protein compare
SMc01222 -0.9 -4.0 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMa0754 -0.9 -1.5 hypothetical protein compare
SMc02615 -0.9 -1.9 signal peptide protein compare
SMc02659 -0.9 -3.1 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc01110 -0.9 -2.9 DNA-binding protein compare
SMa0144 -0.8 -0.7 hypothetical protein compare
SM_b20313 -0.8 -2.4 glycerone kinase compare
SMc02306 -0.8 -1.0 hypothetical protein compare
SMc04220 -0.8 -1.2 transcriptional regulator compare
SMc04174 -0.8 -1.2 signal peptide protein compare
SMc04042 -0.8 -4.1 monophosphatase compare
SMc04404 -0.8 -1.1 amino acid efflux transmembrane protein compare
SMc01845 -0.8 -1.1 transglycosylase transmembrane protein compare
SM_b20329 -0.8 -5.1 required for glucoside 3-dehydrogenase activity on raffinose or trehalose (thuA) (EC 1.1.99.13) (from data) compare
SM_b21482 -0.8 -1.0 hypothetical protein compare
SM_b21501 -0.8 -2.0 hypothetical protein compare
SMc02366 -0.8 -5.7 transcriptional regulator compare
SMc04005 -0.8 -3.8 pyruvate kinase compare
SMc02573 -0.8 -1.2 hypothetical protein compare
SMc00761 -0.8 -4.7 oxidoreductase compare
SMc01568 -0.8 -0.5 hypothetical protein compare
SMc04348 -0.8 -0.7 transcriptional regulator compare
SMa1697 -0.8 -1.5 hypothetical protein compare
SMc00555 -0.8 -1.0 colicin V production transmembrane protein compare
SMa2299 -0.8 -1.9 hypothetical protein compare
SMc04052 -0.8 -1.1 transcriptional regulator compare
SMc03826 -0.8 -0.5 argininosuccinate synthase compare
SMc00349 -0.8 -3.9 GTP-binding protein LepA compare
SM_b21441 -0.7 -1.7 inosine-5'-monophosphate dehydrogenase compare
SMa0293 -0.7 -1.9 hypothetical protein compare
SMc01208 -0.7 -1.0 peptidyl-prolyl cis-trans isomerase B protein compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Mannitol in Sinorhizobium meliloti 1021

For carbon source D-Mannitol across organisms