Experiment set9IT060 for Sinorhizobium meliloti 1021

Compare to:

D-Mannitol carbon source

200 most important genes:

  gene name fitness t score description  
SMc02572 -8.9 -6.1 imidazole glycerol phosphate synthase subunit HisH compare
SMc02123 -8.1 -3.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc02766 -7.7 -12.8 tryptophan synthase subunit beta compare
SMc01843 -7.4 -5.1 5,10-methylenetetrahydrofolate reductase compare
SMc03797 -7.4 -5.1 homoserine O-succinyltransferase compare
SMc04002 -7.2 -7.0 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02765 -7.0 -12.6 tryptophan synthase subunit alpha compare
SM_b21175 -6.9 -4.7 phosphate uptake ABC transporter permease compare
SMc01494 -6.8 -10.4 phosphoserine phosphatase compare
SMc00917 -6.7 -4.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00236 -6.7 -6.5 Indole-3-glycerol phosphate synthase compare
SMc00614 -6.6 -6.5 phosphoribosylglycinamide formyltransferase compare
SMc00235 -6.6 -6.4 anthranilate phosphoribosyltransferase compare
SMc02767 -6.5 -9.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc04045 -6.5 -6.4 dihydroxy-acid dehydratase compare
SMc01726 -6.5 -6.3 acetylglutamate kinase compare
SMc04026 -6.4 -7.6 glutamate synthase compare
SMc02245 -6.3 -4.4 dihydroorotate dehydrogenase 2 compare
SMc02717 -6.2 -9.5 2-isopropylmalate synthase compare
SMc00711 -6.2 -4.3 cyclohexadienyl dehydrogenase compare
SM_b21174 -6.2 -4.3 phosphate uptake ABC transporter permease compare
SMc01431 -6.2 -8.5 acetolactate synthase 3 catalytic subunit compare
SMa1635 -6.1 -2.6 hypothetical protein compare
SMc00131 -6.0 -14.5 transcriptional regulator compare
SMc01054 -6.0 -5.8 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00495 -6.0 -5.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04028 -6.0 -12.2 glutamate synthase compare
SMc00090 -5.9 -8.1 sulfate adenylyltransferase compare
SMc03895 -5.9 -13.7 pyruvate carboxylase compare
SMc03112 -5.9 -14.7 B12-dependent methionine synthase compare
SMc03823 -5.8 -11.8 isopropylmalate isomerase large subunit compare
SMc00993 -5.8 -8.9 phosphoribosylamine--glycine ligase compare
SMc04405 -5.8 -7.7 3-isopropylmalate dehydrogenase compare
SMc01801 -5.8 -4.0 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02899 -5.7 -11.4 prephenate dehydratase compare
SMc01004 -5.6 -11.4 phosphoribosyl-AMP cyclohydrolase compare
SMc02569 -5.6 -5.4 imidazole glycerol phosphate synthase subunit HisF compare
SMc02164 -5.5 -3.5 fructokinase compare
SMc00493 -5.5 -6.6 phosphoribosylformylglycinamidine synthase I compare
SMc02725 -5.5 -12.2 anthranilate synthase compare
SMc00918 -5.5 -9.1 ATP phosphoribosyltransferase regulatory subunit compare
SMc00615 -5.4 -8.3 phosphoribosylaminoimidazole synthetase compare
SMc00488 -5.4 -18.2 phosphoribosylformylglycinamidine synthase II compare
SMc03777 -5.4 -5.2 gamma-glutamyl phosphate reductase compare
SMc00293 -5.2 -11.2 homoserine dehydrogenase compare
SMc02217 -5.2 -6.2 O-succinylhomoserine sulfhydrylase compare
SMc00092 -5.2 -12.5 phosphoadenosine phosphosulfate reductase compare
SMc00640 -5.1 -7.8 phosphoserine aminotransferase compare
SMc00554 -5.1 -6.1 amidophosphoribosyltransferase compare
SMc02574 -5.1 -7.0 imidazoleglycerol-phosphate dehydratase compare
SMc02137 -5.1 -3.5 ornithine carbamoyltransferase compare
SMc04088 -5.0 -9.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02707 -4.9 -5.8 hypothetical protein compare
SMc00091 -4.9 -10.5 sulfate adenylyltransferase compare
SMc02124 -4.8 -14.6 nitrite reductase compare
SMc02138 -4.8 -6.1 acetylornithine transaminase compare
SMc00412 -4.8 -3.3 orotidine 5'-phosphate decarboxylase compare
SMc01501 -4.6 -2.8 mannitol 2-dehydrogenase compare
SMc02570 -4.5 -5.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02165 -4.5 -4.4 orotate phosphoribosyltransferase compare
SMc04001 -4.5 -1.9 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00494 -4.4 -2.6 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc03229 -4.3 -2.9 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc01430 -4.2 -7.8 acetolactate synthase 3 regulatory subunit compare
SMc03981 -4.2 -4.8 phosphoglycerate kinase compare
SMc03070 -4.2 -4.1 glucose-6-phosphate 1-dehydrogenase compare
SM_b21177 -4.2 -8.8 phosphate uptake ABC transporter ATP-binding protein compare
SMc03979 -4.0 -3.3 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01053 -3.9 -5.0 siroheme synthase compare
SMc00294 -3.9 -9.4 aminotransferase compare
SMc01498 -3.9 -10.2 sorbitol/mannitol transport inner membrane protein conserved
SMc02166 -3.8 -8.3 dihydroorotase compare
SMc02307 -3.7 -7.5 histidinol dehydrogenase compare
SMc03068 -3.6 -12.4 phosphogluconate dehydratase compare
SMc03776 -3.6 -4.3 gamma-glutamyl kinase compare
SMc01770 -3.5 -1.7 serine hydroxymethyltransferase compare
SMc00641 -3.5 -5.4 D-3-phosphoglycerate dehydrogenase compare
SMc00017 -3.5 -1.9 homoserine kinase compare
SMc02755 -3.4 -4.7 S-adenosyl-L-homocysteine hydrolase compare
SMc01360 -3.4 -2.3 aspartate carbamoyltransferase catalytic subunit compare
SM_b21176 -3.4 -5.6 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00876 -3.4 -2.3 ATP-binding MRP protein compare
SMc01496 -3.2 -9.5 sorbitol-binding periplasmic protein conserved
SMc04346 -3.2 -4.4 ketol-acid reductoisomerase compare
SMc01497 -3.1 -10.5 sorbitol/mannitol transport inner membrane transmembrane protein conserved
SMc01206 -3.1 -1.7 queuine tRNA-ribosyltransferase compare
SMc02246 -3.1 -1.3 hypothetical protein compare
SMc01499 -3.1 -7.6 ATP-binding transport ABC transporter protein conserved
SMc01207 -3.0 -2.1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc03795 -3.0 -2.5 isopropylmalate isomerase small subunit compare
SMc02169 -2.9 -2.4 ABC transporter ATP-binding protein compare
SMc01500 -2.9 -3.1 sorbitol dehydrogenase compare
SMc02171 -2.9 -4.5 periplasmic binding ABC transporter protein compare
SMc02983 -2.7 -7.0 ornithine, DAP, or arginine decarboxylase compare
SMc01578 -2.7 -10.0 aspartate aminotransferase compare
SMc02640 -2.6 -4.9 UDP-glucuronic acid epimerase compare
SMc01361 -2.3 -2.2 dihydroorotase compare
SMc00914 -2.3 -2.6 oxidoreductase compare
SMc03924 -2.2 -8.3 glycogen synthase compare
SMc02055 -2.2 -1.9 phytoene synthase compare
SM_b20307 -2.2 -1.5 dihydroxyacetone kinase compare
SMc02167 -2.1 -5.6 fructose transport system kinase compare
SMc02714 -2.1 -1.9 hypothetical protein compare
SMc02505 -2.1 -1.1 hypothetical protein compare
SMc01028 -2.0 -10.5 phosphopyruvate hydratase compare
SMc01124 -2.0 -6.7 PII uridylyl-transferase compare
SMc03978 -2.0 -1.4 transketolase compare
SMc01852 -2.0 -9.6 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc03153 -1.9 -4.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc01881 -1.9 -2.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc02362 -1.8 -1.2 cytochrome c-type biogenesis protein CcmE compare
SMc01880 -1.8 -1.7 pantoate--beta-alanine ligase compare
SMc02641 -1.7 -2.3 UDP-glucose 6-dehydrogenase compare
SMc02170 -1.7 -3.9 ABC transporter permease compare
SMc01280 -1.7 -2.2 protease compare
SMc02838 -1.6 -5.4 phosphoglyceromutase compare
SMc03069 -1.6 -1.8 6-phosphogluconolactonase compare
SMc00012 -1.6 -1.3 cytochrome C oxidase assembly protein compare
SMc04000 -1.6 -1.6 hypothetical protein compare
SMc00555 -1.5 -1.6 colicin V production transmembrane protein compare
SMc01089 -1.5 -1.5 hypothetical protein compare
SMc00414 -1.4 -6.7 hypothetical protein compare
SMc00928 -1.4 -1.1 signal peptide protein compare
SMc01440 -1.4 -4.4 hydrolase serine protease transmembrane protein compare
SMc01220 -1.4 -3.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc01042 -1.4 -3.6 nitrogen regulation protein compare
SMa1323 -1.4 -2.2 Transcription regulator compare
SMc02897 -1.4 -2.0 cytochrome C transmembrane protein compare
SMc00450 -1.4 -1.2 protoheme IX farnesyltransferase compare
SMc02407 -1.3 -5.6 hypothetical protein compare
SMc00302 -1.3 -1.2 hypothetical protein compare
SMa1924 -1.3 -0.9 hypothetical protein compare
SMc01503 -1.3 -7.0 sugar kinase conserved
SMc02510 -1.3 -0.7 ferric uptake regulation protein compare
SMc01441 -1.3 -4.3 membrane bound protease compare
SMc04005 -1.2 -5.2 pyruvate kinase compare
SM_b20921 -1.2 -2.6 hypothetical protein compare
SMc00321 -1.2 -3.0 tRNA pseudouridine synthase B compare
SMc03850 -1.2 -0.6 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc00349 -1.2 -5.1 GTP-binding protein LepA compare
SMc00761 -1.2 -5.6 oxidoreductase compare
SMc01368 -1.2 -4.3 transport transmembrane protein compare
SMc00982 -1.2 -3.9 dioxygenase compare
SMc00080 -1.1 -1.9 hypothetical protein compare
SMc02778 -1.1 -1.4 hydroxyacid aldolase compare
SMc01043 -1.1 -4.9 nitrogen assimilation regulatory protein compare
SMa0643 -1.1 -1.6 transposase compare
SMa0674 -1.1 -1.4 hypothetical protein compare
SMc04121 -1.1 -1.2 uracil phosphoribosyltransferase compare
SM_b21591 -1.1 -2.2 GntR family transcriptional regulator compare
SMc00815 -1.1 -0.7 inosine 5'-monophosphate dehydrogenase compare
SMc00963 -1.1 -1.5 hypothetical protein compare
SMa5018 -1.0 -2.0 hypothetical protein compare
SMc01041 -1.0 -3.2 NIFR3-like protein compare
SMc04348 -1.0 -1.1 transcriptional regulator compare
SMc00451 -1.0 -4.7 processing protease compare
SMc02659 -1.0 -2.2 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc03763 -1.0 -0.9 cytosine-specific methyltransferase compare
SMc02112 -1.0 -3.6 hypothetical protein compare
SM_b20616 -1.0 -1.1 thiamine biosynthesis oxidoreductase compare
SM_b20089 -1.0 -1.4 hypothetical protein compare
SMc02434 -1.0 -2.1 hypothetical protein compare
SMc00404 -1.0 -1.0 hypothetical protein compare
SMc00067 -1.0 -3.4 outer-membranne lipoprotein compare
SMc02050 -0.9 -2.6 trigger factor compare
SMc01447 -0.9 -1.0 hypothetical protein compare
SMc02858 -0.9 -0.5 chaperone protein DnaJ compare
SMc02367 -0.9 -5.9 sensor histidine kinase transmembrane protein compare
SMc01147 -0.9 -0.6 coproporphyrinogen III oxidase compare
SMc04391 -0.9 -1.2 3-ketoacyl-ACP reductase compare
SMc00838 -0.9 -4.2 hypothetical protein compare
SMc00013 -0.9 -1.2 cytochrome C oxidase subunit III transmembrane protein compare
SM_b20953 -0.9 -0.9 hypothetical protein compare
SMc02724 -0.9 -1.8 hypothetical protein compare
SMc00580 -0.9 -1.6 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc00513 -0.9 -3.1 amino acid-binding periplasmic protein compare
SMc02753 -0.9 -0.6 PTS system transporter subunit IIA compare
SMc03072 -0.9 -1.4 hypothetical protein compare
SM_b20602 -0.9 -2.2 branched-chain amino acid ABC transporter ATP-binding protein compare
SMc02366 -0.9 -6.5 transcriptional regulator compare
SMa1052 -0.9 -1.3 hypothetical protein compare
SMc00566 -0.8 -1.8 hypothetical protein compare
SMc00981 -0.8 -2.9 ferredoxin protein compare
SMc00427 -0.8 -0.9 peptide chain release factor RF-3 protein compare
SMc02058 -0.8 -2.1 YAJC protein compare
SMc03980 -0.8 -2.8 hypothetical protein compare
SMc01258 -0.8 -3.3 hypothetical protein compare
SMc01454 -0.8 -5.3 hypothetical protein compare
SMc02365 -0.8 -3.1 protease precursor protein compare
SMc01438 -0.8 -2.6 protease precursor signal peptide protein compare
SM_b20330 -0.8 -3.5 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) (from data) compare
SMa1365 -0.8 -0.7 ATP-binding protein compare
SMc02677 -0.8 -2.5 pyrroline-5-carboxylate reductase compare
SM_b20329 -0.8 -4.7 required for glucoside 3-dehydrogenase activity on raffinose or trehalose (thuA) (EC 1.1.99.13) (from data) compare
SMa0882 -0.8 -1.1 hypothetical protein compare
SMc03801 -0.8 -1.8 thioredoxin protein compare
SMa0232 -0.8 -2.2 hypothetical protein compare
SMc00760 -0.8 -1.8 recombinase A compare
SM_b20827 -0.8 -1.5 transposase compare
SMc01099 -0.8 -1.4 tRNA pseudouridine synthase A compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source D-Mannitol in Sinorhizobium meliloti 1021

For carbon source D-Mannitol across organisms