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Experiment set9IT040 for
Methanococcus maripaludis S2
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H2 McCas with 1 hour oxygen exposure
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS01570
+1.5
3.2
hypothetical protein
compare
MMP
_RS03340
+1.3
1.4
ABC transporter ATP-binding protein
compare
MMP
_RS06540
+1.1
2.8
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS00655
+1.0
3.8
hypothetical protein
compare
MMP
_RS08310
+1.0
2.6
TMEM165/GDT1 family protein
compare
MMP
_RS08835
+1.0
6.2
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS08390
+1.0
5.0
DUF5400 domain-containing protein
compare
MMP
_RS06325
+1.0
1.8
hypothetical protein
compare
MMP
_RS06905
+0.9
1.9
hypothetical protein
compare
MMP
_RS07925
+0.9
4.0
haloacid dehalogenase
compare
MMP
_RS06590
+0.9
3.3
GNAT family N-acetyltransferase
compare
MMP
_RS02045
+0.9
1.7
tRNA-Met
compare
MMP
_RS07840
+0.9
2.3
ribonuclease III
compare
MMP
_RS08265
+0.9
4.5
rubrerythrin
compare
MMP
_RS00705
+0.9
1.5
hypothetical protein
compare
MMP
_RS08700
+0.9
3.8
hypothetical protein
compare
MMP
_RS04145
+0.8
1.8
hypothetical protein
compare
MMP
_RS05675
+0.8
1.8
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS07850
+0.8
2.6
prephenate dehydratase
compare
MMP
_RS07765
+0.8
4.0
sodium:alanine symporter family protein
compare
MMP
_RS08415
+0.8
1.6
radical SAM protein
compare
MMP
_RS00345
+0.8
3.1
DUF2666 domain-containing protein
compare
MMP
_RS00675
+0.8
0.9
nitroreductase family protein
compare
MMP
_RS07915
+0.8
3.0
DUF4870 domain-containing protein
compare
MMP
_RS06335
+0.8
2.4
HAD family hydrolase
compare
MMP
_RS09035
+0.7
2.8
hypothetical protein
compare
MMP
_RS08775
+0.7
2.6
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS07890
+0.7
1.9
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS08470
+0.7
4.4
ATP-binding cassette domain-containing protein
compare
MMP
_RS03215
+0.7
5.4
MBL fold metallo-hydrolase
compare
MMP
_RS09060
+0.7
5.3
hypothetical protein
compare
MMP
_RS08325
+0.7
3.9
hypothetical protein
compare
MMP
_RS08280
+0.7
2.5
proteasome assembly chaperone family protein
compare
MMP
_RS06910
+0.7
3.6
RlmF-related methyltransferase
compare
MMP
_RS08455
+0.7
2.9
multiprotein bridging factor aMBF1
compare
MMP
_RS06710
+0.7
3.5
selenium-binding protein
compare
MMP
_RS04035
+0.7
1.1
hypothetical protein
compare
MMP
_RS08245
+0.7
3.3
DUF4013 domain-containing protein
compare
MMP
_RS07150
+0.7
2.6
MTH895/ArsE family thioredoxin-like protein
compare
MMP
_RS06190
+0.7
3.5
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMP
_RS07985
+0.7
4.7
nitroreductase family protein
compare
MMP
_RS08395
+0.7
3.0
DsrE family protein
compare
MMP
_RS08235
+0.7
3.7
hypothetical protein
compare
MMP
_RS08640
+0.7
4.1
TIM barrel protein
compare
MMP
_RS08980
+0.7
3.1
hypothetical protein
compare
MMP
_RS08480
+0.6
3.9
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS08430
+0.6
2.5
HAD family hydrolase
compare
MMP
_RS05835
+0.6
0.6
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMP
_RS00395
+0.6
1.3
MGMT family protein
compare
MMP
_RS03305
+0.6
3.0
winged helix-turn-helix domain-containing protein
compare
MMP
_RS01055
+0.6
2.3
hypothetical protein
compare
MMP
_RS06875
+0.6
3.0
FAD-dependent oxidoreductase
compare
MMP
_RS07345
+0.6
3.0
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS00290
+0.6
3.2
hypothetical protein
compare
MMP
_RS06575
+0.6
2.5
fluoride efflux transporter CrcB
compare
MMP
_RS07620
+0.6
2.4
energy-coupling factor ABC transporter substrate-binding protein
compare
MMP
_RS07910
+0.6
2.6
NAD(P)H-hydrate dehydratase
compare
MMP
_RS01260
+0.6
3.2
HDIG domain-containing protein
compare
MMP
_RS07095
+0.6
2.3
PspC domain-containing protein
compare
MMP
_RS08490
+0.6
4.2
hypothetical protein
compare
MMP
_RS05365
+0.6
1.0
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
MMP
_RS00990
+0.6
1.3
hypothetical protein
compare
MMP
_RS06525
+0.6
0.8
YciI family protein
compare
MMP
_RS06585
+0.6
1.2
DMT family protein
compare
MMP
_RS06365
+0.6
1.5
hypothetical protein
compare
MMP
_RS00155
+0.6
3.0
heavy metal-binding domain-containing protein
compare
MMP
_RS09065
+0.6
3.4
hypothetical protein
compare
MMP
_RS04100
+0.6
1.8
hypothetical protein
compare
MMP
_RS05720
+0.5
1.9
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS06440
+0.5
3.3
CBS domain-containing protein
compare
MMP
_RS08575
+0.5
4.3
hypothetical protein
compare
MMP
_RS08160
+0.5
2.0
EamA family transporter
compare
MMP
_RS01630
+0.5
3.7
N-glycosylase/DNA lyase
compare
MMP
_RS08215
+0.5
1.6
DUF483 domain-containing protein
compare
MMP
_RS08085
+0.5
3.2
hypothetical protein
compare
MMP
_RS07155
+0.5
2.9
MFS transporter
compare
MMP
_RS03220
+0.5
1.5
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS03065
+0.5
1.5
AzlC family ABC transporter permease
compare
MMP
_RS01805
+0.5
1.6
NUDIX hydrolase
compare
MMP
_RS08705
+0.5
2.2
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS01475
+0.5
2.8
phosphosulfolactate synthase
compare
MMP
_RS08205
+0.5
2.7
stage II sporulation protein M
compare
MMP
_RS08755
+0.5
3.2
sodium:solute symporter family protein
compare
MMP
_RS06250
+0.5
2.7
hypothetical protein
compare
MMP
_RS07860
+0.5
0.4
hypothetical protein
compare
MMP
_RS06990
+0.5
2.1
CatB-related O-acetyltransferase
compare
MMP
_RS06165
+0.5
3.1
ABC transporter permease
compare
MMP
_RS06965
+0.5
2.0
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS08285
+0.5
2.7
serine/threonine protein kinase
compare
MMP
_RS06305
+0.5
2.6
transporter substrate-binding domain-containing protein
compare
MMP
_RS08260
+0.5
2.5
DUF99 family protein
compare
MMP
_RS06495
+0.5
0.9
YkgJ family cysteine cluster protein
compare
MMP
_RS08080
+0.5
2.4
YchF/TatD family DNA exonuclease
compare
MMP
_RS02740
+0.5
2.2
hypothetical protein
compare
MMP
_RS03300
+0.5
0.4
TOBE domain-containing protein
compare
MMP
_RS00325
+0.5
0.9
RNA-binding protein
compare
MMP
_RS01650
+0.5
0.5
sulfurtransferase TusA family protein
compare
MMP
_RS08770
+0.5
1.9
hypothetical protein
compare
MMP
_RS07590
+0.5
2.4
hypothetical protein
compare
MMP
_RS06480
+0.5
2.4
ABC transporter substrate-binding protein
compare
MMP
_RS08090
+0.5
1.7
hypothetical protein
compare
MMP
_RS05470
+0.5
3.1
DUF523 and DUF1722 domain-containing protein
compare
MMP
_RS01965
+0.5
1.4
DUF1616 domain-containing protein
compare
MMP
_RS01150
+0.5
2.6
aldo/keto reductase
compare
MMP
_RS08380
+0.5
1.8
phosphatase PAP2 family protein
compare
MMP
_RS03910
+0.5
0.8
hypothetical protein
compare
MMP
_RS08410
+0.4
2.0
DUF169 domain-containing protein
compare
MMP
_RS06320
+0.4
1.8
hypothetical protein
compare
MMP
_RS02965
+0.4
1.6
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS05660
+0.4
2.4
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS00145
+0.4
2.2
ATP-dependent Clp protease proteolytic subunit
compare
MMP
_RS00400
+0.4
1.6
tributyrin esterase
compare
MMP
_RS06570
+0.4
1.1
DUF190 domain-containing protein
compare
MMP
_RS04015
+0.4
0.9
hypothetical protein
compare
MMP
_RS01775
+0.4
1.2
TIGR00297 family protein
compare
MMP
_RS00800
+0.4
2.0
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS07905
+0.4
1.6
DUF3343 domain-containing protein
compare
MMP
_RS01620
+0.4
1.5
hypothetical protein
compare
MMP
_RS06045
+0.4
2.7
DNA polymerase
compare
MMP
_RS00760
+0.4
2.3
branched-chain-amino-acid transaminase
compare
MMP
_RS02200
+0.4
2.9
methyl-accepting chemotaxis protein
compare
MMP
_RS06870
+0.4
1.6
DedA family protein
compare
MMP
_RS07100
+0.4
2.8
hypothetical protein
compare
MMP
_RS07970
+0.4
1.1
hypothetical protein
compare
MMP
_RS00565
+0.4
1.7
CBS domain-containing protein
compare
MMP
_RS06155
+0.4
1.4
DUF4186 domain-containing protein
compare
MMP
_RS02720
+0.4
1.2
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS01580
+0.4
2.4
PQQ-binding-like beta-propeller repeat protein
compare
MMP
_RS02370
+0.4
1.8
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS07145
+0.4
2.6
AmmeMemoRadiSam system protein B
compare
MMP
_RS08475
+0.4
2.1
ABC transporter permease
compare
MMP
_RS08240
+0.4
1.5
methanogenesis marker 16 metalloprotein
compare
MMP
_RS02375
+0.4
2.0
hypothetical protein
compare
MMP
_RS08555
+0.4
0.9
hypothetical protein
compare
MMP
_RS07885
+0.4
1.2
tripartite tricarboxylate transporter permease
compare
MMP
_RS06060
+0.4
2.1
hypothetical protein
compare
MMP
_RS00285
+0.4
2.0
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS06610
+0.4
1.1
DUF2334 domain-containing protein
compare
MMP
_RS00195
+0.4
3.3
DUF4013 domain-containing protein
compare
MMP
_RS01160
+0.4
2.1
DMT family transporter
compare
MMP
_RS01455
+0.4
2.0
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS06075
+0.4
2.2
class I SAM-dependent methyltransferase
compare
MMP
_RS00430
+0.4
1.2
hypothetical protein
compare
MMP
_RS06375
+0.4
1.5
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS00435
+0.4
2.4
CPBP family intramembrane metalloprotease
compare
MMP
_RS08725
+0.4
0.4
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS08400
+0.4
0.9
MJ0307 family thioredoxin
compare
MMP
_RS00710
+0.4
0.9
hypothetical protein
compare
MMP
_RS04815
+0.4
1.6
chemotaxis protein CheD
compare
MMP
_RS02300
+0.4
1.6
NAD(P)H-dependent oxidoreductase
compare
MMP
_RS06465
+0.4
2.3
NERD domain-containing protein
compare
MMP
_RS00645
+0.4
2.5
iron ABC transporter permease
compare
MMP
_RS03740
+0.4
1.3
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS06500
+0.4
2.2
ATP-binding protein
compare
MMP
_RS08130
+0.4
1.8
IGHMBP2 family helicase
compare
MMP
_RS03840
+0.3
1.6
hypothetical protein
compare
MMP
_RS07800
+0.3
1.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS00105
+0.3
1.5
hypothetical protein
compare
MMP
_RS05140
+0.3
0.9
helix-turn-helix transcriptional regulator
compare
MMP
_RS07715
+0.3
2.1
YfcE family phosphodiesterase
compare
MMP
_RS04830
+0.3
2.3
chemotaxis protein CheC
compare
MMP
_RS04800
+0.3
1.8
chemotaxis protein CheW
compare
MMP
_RS08290
+0.3
1.4
DNA-binding protein Alba
compare
MMP
_RS08485
+0.3
1.8
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS06185
+0.3
2.0
thermonuclease family protein
compare
MMP
_RS02815
+0.3
1.1
hypothetical protein
compare
MMP
_RS05900
+0.3
1.7
tetratricopeptide repeat protein
compare
MMP
_RS02295
+0.3
2.0
TatD family hydrolase
compare
MMP
_RS06145
+0.3
2.7
hypothetical protein
compare
MMP
_RS07805
+0.3
1.9
ABC transporter permease
compare
MMP
_RS00700
+0.3
1.9
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS01660
+0.3
0.8
hypothetical protein
compare
MMP
_RS00280
+0.3
2.3
DUF2118 domain-containing protein
compare
MMP
_RS06735
+0.3
1.1
class I SAM-dependent rRNA methyltransferase
compare
MMP
_RS09030
+0.3
1.2
hypothetical protein
compare
MMP
_RS01155
+0.3
1.5
XRE family transcriptional regulator
compare
MMP
_RS06560
+0.3
1.9
hypothetical protein
compare
MMP
_RS06150
+0.3
2.2
hypothetical protein
compare
MMP
_RS00950
+0.3
1.4
site-2 protease family protein
compare
MMP
_RS08665
+0.3
2.6
hypothetical protein
compare
MMP
_RS06715
+0.3
2.1
cache domain-containing protein
compare
MMP
_RS06065
+0.3
2.4
iron ABC transporter substrate-binding protein
compare
MMP
_RS06225
+0.3
1.5
DNA double-strand break repair nuclease NurA
compare
MMP
_RS01115
+0.3
1.7
molybdopterin molybdotransferase MoeA
compare
MMP
_RS08685
+0.3
1.9
hypothetical protein
compare
MMP
_RS03965
+0.3
0.8
hypothetical protein
compare
MMP
_RS05715
+0.3
1.4
hypothetical protein
compare
MMP
_RS04205
+0.3
1.4
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS02315
+0.3
1.4
RimK family alpha-L-glutamate ligase
compare
MMP
_RS01685
+0.3
1.0
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS05175
+0.3
0.9
hypothetical protein
compare
MMP
_RS02770
+0.3
1.4
hypothetical protein
compare
MMP
_RS01320
+0.3
1.1
hypothetical protein
compare
MMP
_RS01210
+0.3
1.7
sodium:solute symporter
compare
MMP
_RS01785
+0.3
1.5
hypothetical protein
compare
MMP
_RS01485
+0.3
1.5
right-handed parallel beta-helix repeat-containing protein
compare
MMP
_RS07595
+0.3
1.9
hypothetical protein
compare
MMP
_RS07855
+0.3
1.4
class I SAM-dependent methyltransferase
compare
MMP
_RS08405
+0.3
1.7
MFS transporter
compare
MMP
_RS08250
+0.3
1.4
pyruvate kinase
compare
Specific Phenotypes
For 3 genes in this experiment