Experiment set9IT036 for Klebsiella michiganensis M5al

200 most detrimental genes:

gene	name	fitness	t score	description
BWI76_RS23480		+6.9	37.0	EAL domain-containing protein
BWI76_RS23485		+5.2	31.3	hypothetical protein
BWI76_RS00345		+4.1	8.1	protein disulfide oxidoreductase DsbA
BWI76_RS20360		+3.8	7.0	cell division protein DedD
BWI76_RS15435		+3.6	10.1	hypothetical protein
BWI76_RS09625		+3.0	7.8	hypothetical protein
BWI76_RS17155		+3.0	2.6	hypothetical protein
BWI76_RS21070		+2.8	6.9	outer membrane protein assembly factor BamB
BWI76_RS04530		+2.6	5.3	peptidylprolyl isomerase SurA
BWI76_RS01330		+2.4	3.5	twin-arginine translocase subunit TatC
BWI76_RS16150		+2.4	4.9	IclR family transcriptional regulator
BWI76_RS18550		+2.3	5.1	tRNA-Asn
BWI76_RS14050		+2.2	1.5	AP endonuclease, family 2
BWI76_RS26410		+2.2	1.0	membrane protein
BWI76_RS16715		+2.2	15.0	hypothetical protein
BWI76_RS00600		+2.1	12.8	LacI family transcriptional regulator
BWI76_RS13775		+2.1	1.3	putative FMN-dependent luciferase-like monooxygenase
BWI76_RS05800		+2.1	5.6	phage transcriptional activator, Ogr/delta
BWI76_RS17975		+2.0	6.7	tail-specific protease
BWI76_RS22300		+2.0	5.7	hydrogenase 3 maturation endopeptidase HyCI
BWI76_RS25065		+1.9	3.9	polyribonucleotide nucleotidyltransferase
BWI76_RS24720		+1.7	1.5	hypothetical protein
BWI76_RS10890		+1.7	1.5	glyoxylate/hydroxypyruvate reductase A
BWI76_RS09445		+1.7	1.9	NADPH-dependent oxidoreductase
BWI76_RS11125		+1.7	3.2	metal-dependent hydrolase
BWI76_RS15260		+1.7	3.6	hypothetical protein
BWI76_RS27290		+1.7	12.1	hypothetical protein
BWI76_RS25060		+1.6	4.8	lipoprotein NlpI
BWI76_RS09500		+1.6	1.3	arginine ABC transporter substrate-binding protein
BWI76_RS07510		+1.6	1.5	hypothetical protein
BWI76_RS20930		+1.6	1.3	arsenate reductase (glutaredoxin)
BWI76_RS18815		+1.6	1.9	nitrogenase molybdenum-iron protein alpha chain
BWI76_RS15730		+1.5	4.7	hypothetical protein
BWI76_RS13245		+1.5	2.3	DNA-damage-inducible protein I
BWI76_RS23455		+1.5	1.8	Na(+)-translocating NADH-quinone reductase subunit E
BWI76_RS11455		+1.5	2.9	AraC family transcriptional regulator
BWI76_RS09130		+1.5	1.2	biofilm formation regulatory protein BssR
BWI76_RS04320		+1.5	1.6	transcriptional activator NhaR
BWI76_RS21940		+1.5	1.8	SDR family oxidoreductase
BWI76_RS26095		+1.5	2.4	shikimate kinase
BWI76_RS26875		+1.5	1.9	dipeptide ABC transporter permease DppC
BWI76_RS08620		+1.5	2.3	galactose-1-phosphate uridylyltransferase
BWI76_RS26570		+1.5	2.1	anion permease
BWI76_RS06435		+1.5	1.3	MFS transporter
BWI76_RS05810		+1.4	2.1	hypothetical protein
BWI76_RS14075		+1.4	2.6	TetR family transcriptional regulator
BWI76_RS02440		+1.4	1.3	fumarate reductase subunit D
BWI76_RS08615		+1.4	1.4	galactokinase
BWI76_RS24215		+1.4	2.5	LysR family transcriptional regulator
BWI76_RS26390		+1.4	1.6	cell division protein FtsX
BWI76_RS08380		+1.4	1.4	endonuclease VIII
BWI76_RS04095		+1.4	1.5	dUMP phosphatase
BWI76_RS21370		+1.3	1.8	ATP-dependent RNA helicase SrmB
BWI76_RS04570		+1.3	3.1	RNA polymerase-associated protein RapA
BWI76_RS22620		+1.3	1.1	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BWI76_RS20330		+1.3	1.3	histidine/lysine/arginine/ornithine ABC transporter permease HisQ
BWI76_RS16570		+1.3	1.8	catalase
BWI76_RS03800		+1.3	1.3	hypothetical protein
BWI76_RS07805		+1.3	1.3	sugar ABC transporter permease
BWI76_RS07785		+1.3	1.6	transcriptional regulator
BWI76_RS03190		+1.2	1.7	hypothetical protein
BWI76_RS24255		+1.2	2.1	thiol:disulfide oxidoreductase
BWI76_RS07385		+1.2	1.3	short-chain dehydrogenase/reductase SDR
BWI76_RS04240		+1.2	3.7	thr operon leader peptide
BWI76_RS11375		+1.2	3.1	iron-dicitrate transporter permease subunit
BWI76_RS25425		+1.2	0.8	arginine repressor
BWI76_RS14750		+1.2	1.6	transcriptional regulator
BWI76_RS14975		+1.2	1.4	glyoxalase-like domain protein
BWI76_RS19700		+1.2	3.1	deoxyribonuclease IV
BWI76_RS16240		+1.2	3.0	anti-adapter protein IraM
BWI76_RS15650		+1.1	2.6	gp5
BWI76_RS06080		+1.1	1.6	taurine dioxygenase
BWI76_RS10430		+1.1	1.0	thiol:disulfide interchange protein DsbG
BWI76_RS25230		+1.1	5.1	phospholipid ABC transporter ATP-binding protein MlaF
BWI76_RS19920		+1.1	2.3	hybrid sensor histidine kinase/response regulator
BWI76_RS17665		+1.1	1.4	proteasome-type protease
BWI76_RS25225		+1.1	2.6	ABC transporter permease
BWI76_RS18670		+1.1	2.4	hypothetical protein
BWI76_RS19090		+1.1	4.7	polysaccharide export protein Wza
BWI76_RS01350		+1.1	1.5	NAD(P)H-flavin reductase
BWI76_RS18390		+1.1	2.2	hypothetical protein
BWI76_RS10380		+1.1	1.7	polar amino acid ABC transporter inner membrane subunit
BWI76_RS01840		+1.1	0.9	maltose ABC transporter, ATPase component (MalK) (from data)
BWI76_RS21675		+1.1	1.7	hypothetical protein
BWI76_RS03180		+1.1	1.8	phage transcriptional regulator, AlpA
BWI76_RS24040		+1.1	3.2	hypothetical protein
BWI76_RS06050		+1.1	1.7	MFS transporter family glucose-6-phosphate receptor UhpC
BWI76_RS27305		+1.1	6.3	glycosyl transferase
BWI76_RS05885		+1.1	1.8	anion permease
BWI76_RS11185		+1.0	1.6	ligand-gated channel protein
BWI76_RS15975		+1.0	1.3	hypothetical protein
BWI76_RS13610		+1.0	1.8	sugar transporter
BWI76_RS16665		+1.0	2.0	ABC transporter permease
BWI76_RS27275		+1.0	3.3	hypothetical protein
BWI76_RS18730		+1.0	1.6	LysR family transcriptional regulator
BWI76_RS11275		+1.0	5.5	sensor protein PhoQ
BWI76_RS20220		+1.0	2.0	sugar phosphatase
BWI76_RS12925		+1.0	2.0	efflux transporter periplasmic adaptor subunit
BWI76_RS24400		+1.0	4.7	outer membrane channel protein TolC
BWI76_RS19895		+1.0	1.3	bifunctional transcriptional regulator/O6-methylguanine-DNA methyltransferase
BWI76_RS17980		+1.0	2.7	RNA chaperone ProQ
BWI76_RS06230		+1.0	1.0	DNA-binding response regulator
BWI76_RS26980		+1.0	1.3	cold-shock protein
BWI76_RS20650		+1.0	1.9	phosphoenolpyruvate--protein phosphotransferase
BWI76_RS15680		+1.0	1.9	hypothetical protein
BWI76_RS18080		+1.0	2.0	protein YebE
BWI76_RS26205		+1.0	2.1	glucose-1-phosphate adenylyltransferase
BWI76_RS13320		+1.0	0.8	putative LpxA-like enzyme
BWI76_RS10045		+1.0	1.3	23S rRNA (cytosine(1962)-C(5))-methyltransferase
BWI76_RS14240		+1.0	1.3	thiol reductase thioredoxin
BWI76_RS16040		+1.0	1.4	biotin-independent malonate decarboxylase subunit gamma
BWI76_RS16505		+1.0	1.3	MFS transporter
BWI76_RS19040		+1.0	3.6	hypothetical protein
BWI76_RS20310		+1.0	1.3	hypothetical protein
BWI76_RS12270		+1.0	1.0	hypothetical protein
BWI76_RS22405		+1.0	1.4	PTS cellobiose transporter subunit IIC
BWI76_RS16285		+1.0	2.1	hypothetical protein
BWI76_RS03620		+1.0	1.0	TetR family transcriptional regulator
BWI76_RS04015		+1.0	1.9	membrane protein
BWI76_RS15590		+1.0	0.9	hypothetical protein
BWI76_RS16830		+1.0	2.1	ABC transporter
BWI76_RS01845		+0.9	1.7	maltoporin
BWI76_RS27835		+0.9	1.9	acyltransferase
BWI76_RS23310		+0.9	3.1	lysophospholipid transporter LplT
BWI76_RS19450		+0.9	1.4	hypothetical protein
BWI76_RS25070		+0.9	1.7	hypothetical protein
BWI76_RS22690		+0.9	2.4	adenylyl-sulfate kinase
BWI76_RS12895		+0.9	1.2	hypothetical protein
BWI76_RS22950		+0.9	1.8	membrane protein
BWI76_RS17565		+0.9	1.5	hypothetical protein
BWI76_RS11390		+0.9	1.6	iron dicitrate transport regulator FecR
BWI76_RS18345		+0.9	6.3	transcriptional regulator SdiA
BWI76_RS23330		+0.9	5.2	transcriptional regulator GalR
BWI76_RS15330		+0.9	1.3	urea ABC transporter permease subunit UrtC
BWI76_RS00105		+0.9	1.4	NAD(P)H-dependent oxidoreductase
BWI76_RS19605		+0.9	1.5	CidB/LrgB family autolysis modulator
BWI76_RS12870		+0.9	1.1	putative phytanoyl-CoA dioxygenase
BWI76_RS15060		+0.9	1.5	MarR family transcriptional regulator
BWI76_RS14230		+0.9	1.5	flavin monoamine oxidase family protein
BWI76_RS04515		+0.9	1.5	Co2+/Mg2+ efflux protein ApaG
BWI76_RS22685		+0.9	3.9	hypothetical protein
BWI76_RS24620		+0.9	1.3	PadR family transcriptional regulator
BWI76_RS19760		+0.9	1.2	GTP-binding protein
BWI76_RS24025		+0.9	2.8	agmatinase
BWI76_RS14305		+0.9	2.2	metallophosphoesterase
BWI76_RS02530		+0.9	1.1	tRNA dimethylallyltransferase
BWI76_RS06815		+0.9	2.1	adenine phosphoribosyltransferase
BWI76_RS23295		+0.9	1.7	tellurium resistance protein TerC
BWI76_RS12155		+0.9	1.1	hypothetical protein
BWI76_RS19470		+0.9	1.8	DNA-binding response regulator
BWI76_RS18290		+0.9	2.5	hypothetical protein
BWI76_RS09145		+0.9	1.2	serine-type D-Ala-D-Ala carboxypeptidase
BWI76_RS05915		+0.9	0.9	helix-turn-helix transcriptional regulator
BWI76_RS20440		+0.9	2.0	50S ribosomal protein L3 N(5)-glutamine methyltransferase
BWI76_RS08215		+0.9	2.0	glucosamine-6-phosphate deaminase
BWI76_RS21375		+0.8	1.2	autonomous glycyl radical cofactor GrcA
BWI76_RS12055		+0.8	2.6	DNA single-strand annealing protein RecT-like protein
BWI76_RS19515		+0.8	3.1	D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data)
BWI76_RS04700		+0.8	2.3	acetolactate synthase small subunit
BWI76_RS18715		+0.8	3.6	hypothetical protein
BWI76_RS24660		+0.8	1.0	autoinducer 2 ABC transporter ATP-binding protein LsrA
BWI76_RS15740		+0.8	2.1	HNH endonuclease
BWI76_RS12420		+0.8	0.9	peptide ABC transporter substrate-binding protein SapA
BWI76_RS07435		+0.8	2.4	LacI family transcriptional regulator
BWI76_RS17110		+0.8	1.4	vitamin B12 ABC transporter permease BtuC
BWI76_RS20800		+0.8	1.1	carboxysome shell protein
BWI76_RS13220		+0.8	1.8	N-acetyltransferase
BWI76_RS25910		+0.8	1.5	peptidyl-prolyl cis-trans isomerase
BWI76_RS16910		+0.8	0.9	2-keto-4-pentenoate hydratase
BWI76_RS22895		+0.8	1.6	FAD-dependent oxidoreductase
BWI76_RS19010		+0.8	1.5	polysaccharide pyruvyl transferase yvff
BWI76_RS12790		+0.8	1.1	lactate dehydrogenase
BWI76_RS16320		+0.8	1.5	methionine ABC transporter substrate-binding protein
BWI76_RS16645		+0.8	1.0	DeoR family transcriptional regulator
BWI76_RS26275		+0.8	2.1	gamma-glutamyltransferase
BWI76_RS10435		+0.8	1.1	suppressor for copper-sensitivity C
BWI76_RS13590		+0.8	1.6	hypothetical protein
BWI76_RS11380		+0.8	1.4	iron-dicitrate transporter substrate-binding subunit
BWI76_RS15175		+0.8	1.2	N-acetyltransferase
BWI76_RS05325		+0.8	1.6	hypothetical protein
BWI76_RS26280		+0.8	1.1	hypothetical protein
BWI76_RS08350		+0.8	2.5	carboxylase
BWI76_RS27645		+0.8	2.0	ADP-ribose pyrophosphatase
BWI76_RS21290		+0.8	1.1	DNA-binding transcriptional regulator
BWI76_RS23525		+0.8	1.4	EamA family transporter
BWI76_RS15050		+0.8	0.7	sugar transporter
BWI76_RS15340		+0.7	1.4	urea ABC transporter substrate-binding protein
BWI76_RS22870		+0.7	3.0	LOG family protein
BWI76_RS16445		+0.7	1.6	auxiliary transporter membrane fusion protein
BWI76_RS26260		+0.7	1.9	hypothetical protein
BWI76_RS14010		+0.7	1.2	SDR family oxidoreductase
BWI76_RS14375		+0.7	2.1	hypothetical protein
BWI76_RS00725		+0.7	1.7	periplasmic repressor CpxP
BWI76_RS05040		+0.7	1.3	type II secretion system protein N
BWI76_RS01535		+0.7	1.5	thiazole synthase
BWI76_RS13225		+0.7	1.0	hypothetical protein
BWI76_RS08605		+0.7	1.3	phosphoglyceromutase
BWI76_RS06770		+0.7	3.8	Hha toxicity attenuator
BWI76_RS18710		+0.7	4.3	GGDEF-domain containing protein
BWI76_RS20795		+0.7	0.9	ethanolamine catabolic microcompartment shell protein EutN

Specific Phenotypes

For 3 genes in this experiment