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Experiment set9IT033 for
Methanococcus maripaludis S2
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H2 McCas with 5 minute oxygen exposure
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS08265
+1.2
6.2
rubrerythrin
compare
MMP
_RS03300
+1.1
1.2
TOBE domain-containing protein
compare
MMP
_RS08725
+1.1
0.9
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS08775
+1.1
4.7
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS00395
+1.0
2.3
MGMT family protein
compare
MMP
_RS07840
+1.0
3.1
ribonuclease III
compare
MMP
_RS00655
+1.0
3.0
hypothetical protein
compare
MMP
_RS03340
+0.9
1.0
ABC transporter ATP-binding protein
compare
MMP
_RS08310
+0.9
2.3
TMEM165/GDT1 family protein
compare
MMP
_RS00675
+0.9
1.1
nitroreductase family protein
compare
MMP
_RS08430
+0.9
4.3
HAD family hydrolase
compare
MMP
_RS06540
+0.9
2.2
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS06325
+0.9
1.7
hypothetical protein
compare
MMP
_RS01570
+0.8
1.7
hypothetical protein
compare
MMP
_RS07915
+0.8
2.6
DUF4870 domain-containing protein
compare
MMP
_RS08455
+0.8
4.3
multiprotein bridging factor aMBF1
compare
MMP
_RS07925
+0.8
3.7
haloacid dehalogenase
compare
MMP
_RS09035
+0.8
2.6
hypothetical protein
compare
MMP
_RS08555
+0.8
2.1
hypothetical protein
compare
MMP
_RS00155
+0.8
4.7
heavy metal-binding domain-containing protein
compare
MMP
_RS00450
+0.8
2.0
4Fe-4S binding protein
compare
MMP
_RS08390
+0.8
3.5
DUF5400 domain-containing protein
compare
MMP
_RS07985
+0.8
5.6
nitroreductase family protein
compare
MMP
_RS08760
+0.8
3.1
hypothetical protein
compare
MMP
_RS01630
+0.8
5.6
N-glycosylase/DNA lyase
compare
MMP
_RS01055
+0.7
2.6
hypothetical protein
compare
MMP
_RS00945
+0.7
1.3
PadR family transcriptional regulator
compare
MMP
_RS00635
+0.7
3.9
energy-coupling factor transporter transmembrane protein EcfT
compare
MMP
_RS08700
+0.7
3.9
hypothetical protein
compare
MMP
_RS08325
+0.7
4.4
hypothetical protein
compare
MMP
_RS06590
+0.7
1.7
GNAT family N-acetyltransferase
compare
MMP
_RS08640
+0.7
5.5
TIM barrel protein
compare
MMP
_RS08480
+0.7
4.6
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS00290
+0.7
3.2
hypothetical protein
compare
MMP
_RS00990
+0.7
1.7
hypothetical protein
compare
MMP
_RS07885
+0.7
2.7
tripartite tricarboxylate transporter permease
compare
MMP
_RS02045
+0.7
1.4
tRNA-Met
compare
MMP
_RS06965
+0.7
3.8
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS05720
+0.7
2.1
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS03800
+0.7
3.4
hypothetical protein
compare
MMP
_RS01455
+0.7
3.5
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS08470
+0.7
3.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS08205
+0.7
3.9
stage II sporulation protein M
compare
MMP
_RS08575
+0.6
5.0
hypothetical protein
compare
MMP
_RS08980
+0.6
2.2
hypothetical protein
compare
MMP
_RS07895
+0.6
2.3
cytochrome c
compare
MMP
_RS08315
+0.6
2.0
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS06375
+0.6
2.0
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS07890
+0.6
1.7
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS07775
+0.6
2.4
alanine dehydrogenase
compare
MMP
_RS07765
+0.6
3.1
sodium:alanine symporter family protein
compare
MMP
_RS07095
+0.6
2.4
PspC domain-containing protein
compare
MMP
_RS07805
+0.6
2.8
ABC transporter permease
compare
MMP
_RS08835
+0.6
4.1
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS00770
+0.6
2.9
hypothetical protein
compare
MMP
_RS08085
+0.6
4.6
hypothetical protein
compare
MMP
_RS08500
+0.6
1.6
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS07900
+0.6
1.1
YeeE/YedE family protein
compare
MMP
_RS08755
+0.6
4.5
sodium:solute symporter family protein
compare
MMP
_RS09065
+0.6
4.2
hypothetical protein
compare
MMP
_RS03065
+0.6
1.4
AzlC family ABC transporter permease
compare
MMP
_RS08260
+0.6
3.9
DUF99 family protein
compare
MMP
_RS06305
+0.6
3.0
transporter substrate-binding domain-containing protein
compare
MMP
_RS07850
+0.6
1.4
prephenate dehydratase
compare
MMP
_RS06155
+0.6
2.1
DUF4186 domain-containing protein
compare
MMP
_RS02495
+0.6
1.9
hypothetical protein
compare
MMP
_RS08485
+0.6
2.6
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS08705
+0.6
3.0
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS07100
+0.5
3.5
hypothetical protein
compare
MMP
_RS03910
+0.5
1.4
hypothetical protein
compare
MMP
_RS07910
+0.5
1.7
NAD(P)H-hydrate dehydratase
compare
MMP
_RS06335
+0.5
2.0
HAD family hydrolase
compare
MMP
_RS08395
+0.5
1.8
DsrE family protein
compare
MMP
_RS06190
+0.5
3.8
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMP
_RS06910
+0.5
3.6
RlmF-related methyltransferase
compare
MMP
_RS08160
+0.5
2.4
EamA family transporter
compare
MMP
_RS08380
+0.5
3.1
phosphatase PAP2 family protein
compare
MMP
_RS09060
+0.5
3.8
hypothetical protein
compare
MMP
_RS01855
+0.5
2.7
2-hydroxyacyl-CoA dehydratase family protein
compare
MMP
_RS07835
+0.5
1.6
TldD/PmbA family protein
compare
MMP
_RS01260
+0.5
2.2
HDIG domain-containing protein
compare
MMP
_RS00285
+0.5
2.6
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS06500
+0.5
3.0
ATP-binding protein
compare
MMP
_RS09030
+0.5
2.0
hypothetical protein
compare
MMP
_RS04830
+0.5
3.7
chemotaxis protein CheC
compare
MMP
_RS08840
+0.5
2.9
class I SAM-dependent methyltransferase
compare
MMP
_RS04205
+0.5
2.3
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS01580
+0.5
2.6
PQQ-binding-like beta-propeller repeat protein
compare
MMP
_RS08490
+0.5
3.6
hypothetical protein
compare
MMP
_RS01865
+0.5
0.9
GPR1/FUN34/YaaH family transporter
compare
MMP
_RS00630
+0.5
2.5
ECF transporter S component
compare
MMP
_RS06075
+0.5
2.3
class I SAM-dependent methyltransferase
compare
MMP
_RS01435
+0.5
1.8
DMT family transporter
compare
MMP
_RS05155
+0.5
2.7
hypothetical protein
compare
MMP
_RS01200
+0.5
1.8
hypothetical protein
compare
MMP
_RS07715
+0.5
2.6
YfcE family phosphodiesterase
compare
MMP
_RS08215
+0.5
1.5
DUF483 domain-containing protein
compare
MMP
_RS07590
+0.5
2.6
hypothetical protein
compare
MMP
_RS04800
+0.5
3.4
chemotaxis protein CheW
compare
MMP
_RS00400
+0.4
2.7
tributyrin esterase
compare
MMP
_RS01120
+0.4
2.2
permease
compare
MMP
_RS08280
+0.4
1.4
proteasome assembly chaperone family protein
compare
MMP
_RS00940
+0.4
3.1
daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
compare
MMP
_RS06490
+0.4
1.5
hypothetical protein
compare
MMP
_RS06520
+0.4
2.4
DUF1786 domain-containing protein
compare
MMP
_RS00545
+0.4
1.2
XRE family transcriptional regulator
compare
MMP
_RS02315
+0.4
2.7
RimK family alpha-L-glutamate ligase
compare
MMP
_RS06990
+0.4
1.6
CatB-related O-acetyltransferase
compare
MMP
_RS07770
+0.4
1.8
alanine racemase
compare
MMP
_RS08475
+0.4
2.1
ABC transporter permease
compare
MMP
_RS00980
+0.4
2.4
hypothetical protein
compare
MMP
_RS08245
+0.4
2.3
DUF4013 domain-containing protein
compare
MMP
_RS08080
+0.4
2.1
YchF/TatD family DNA exonuclease
compare
MMP
_RS00345
+0.4
2.2
DUF2666 domain-containing protein
compare
MMP
_RS01065
+0.4
2.9
alpha/beta hydrolase
compare
MMP
_RS03740
+0.4
1.6
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS06320
+0.4
1.5
hypothetical protein
compare
MMP
_RS08235
+0.4
2.0
hypothetical protein
compare
MMP
_RS07650
+0.4
3.0
TldD/PmbA family protein
compare
MMP
_RS06560
+0.4
2.4
hypothetical protein
compare
MMP
_RS06435
+0.4
2.6
CBS domain-containing protein
compare
MMP
_RS06045
+0.4
2.7
DNA polymerase
compare
MMP
_RS01650
+0.4
0.4
sulfurtransferase TusA family protein
compare
MMP
_RS04055
+0.4
0.8
hypothetical protein
compare
MMP
_RS02200
+0.4
3.1
methyl-accepting chemotaxis protein
compare
MMP
_RS00660
+0.4
2.8
alkaline phosphatase family protein
compare
MMP
_RS07345
+0.4
1.8
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS06300
+0.4
1.7
ABC transporter substrate-binding protein
compare
MMP
_RS03465
+0.4
0.6
adenine phosphoribosyltransferase
compare
MMP
_RS08130
+0.4
2.4
IGHMBP2 family helicase
compare
MMP
_RS08405
+0.4
2.4
MFS transporter
compare
MMP
_RS05365
+0.4
1.0
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
MMP
_RS06905
+0.4
1.1
hypothetical protein
compare
MMP
_RS04190
+0.4
2.5
hypothetical protein
compare
MMP
_RS06875
+0.4
1.8
FAD-dependent oxidoreductase
compare
MMP
_RS04825
+0.4
2.8
protein-glutamate O-methyltransferase CheR
compare
MMP
_RS00950
+0.4
2.3
site-2 protease family protein
compare
MMP
_RS07595
+0.4
2.6
hypothetical protein
compare
MMP
_RS05665
+0.4
2.4
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS07145
+0.4
2.3
AmmeMemoRadiSam system protein B
compare
MMP
_RS07815
+0.4
0.6
DUF2120 domain-containing protein
compare
MMP
_RS06460
+0.4
1.2
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMP
_RS04145
+0.4
0.8
hypothetical protein
compare
MMP
_RS07155
+0.4
1.9
MFS transporter
compare
MMP
_RS04805
+0.4
2.4
chemotaxis response regulator protein-glutamate methylesterase
compare
MMP
_RS08285
+0.4
1.8
serine/threonine protein kinase
compare
MMP
_RS08415
+0.4
0.9
radical SAM protein
compare
MMP
_RS07855
+0.4
1.9
class I SAM-dependent methyltransferase
compare
MMP
_RS00800
+0.4
2.4
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS03100
+0.4
0.9
hypothetical protein
compare
MMP
_RS06250
+0.4
1.6
hypothetical protein
compare
MMP
_RS00540
+0.4
1.5
PLP-dependent aminotransferase family protein
compare
MMP
_RS02720
+0.4
0.9
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS02300
+0.4
1.7
NAD(P)H-dependent oxidoreductase
compare
MMP
_RS02490
+0.4
1.3
hypothetical protein
compare
MMP
_RS02375
+0.4
2.1
hypothetical protein
compare
MMP
_RS02500
+0.4
1.7
minichromosome maintenance protein MCM
compare
MMP
_RS08175
+0.4
2.3
7-cyano-7-deazaguanine synthase
compare
MMP
_RS02415
+0.4
1.1
site-specific integrase
compare
MMP
_RS06745
+0.4
1.2
DUF2119 domain-containing protein
compare
MMP
_RS03220
+0.4
1.1
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS07140
+0.4
2.5
TIGR00341 family protein
compare
MMP
_RS06150
+0.4
2.5
hypothetical protein
compare
MMP
_RS06165
+0.3
2.3
ABC transporter permease
compare
MMP
_RS01625
+0.3
2.1
rubredoxin
compare
MMP
_RS07640
+0.3
1.4
mechanosensitive ion channel family protein
compare
MMP
_RS08370
+0.3
0.3
cation:proton antiporter subunit C
compare
MMP
_RS01640
+0.3
1.5
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMP
_RS02590
+0.3
2.1
low molecular weight phosphatase family protein
compare
MMP
_RS01150
+0.3
1.0
aldo/keto reductase
compare
MMP
_RS04945
+0.3
1.4
hypothetical protein
compare
MMP
_RS02745
+0.3
0.9
hypothetical protein
compare
MMP
_RS02825
+0.3
1.9
mechanosensitive ion channel family protein
compare
MMP
_RS03215
+0.3
2.2
MBL fold metallo-hydrolase
compare
MMP
_RS01635
+0.3
1.5
thiamine pyrophosphate-dependent enzyme
compare
MMP
_RS05675
+0.3
1.1
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS07680
+0.3
1.5
DUF366 family protein
compare
MMP
_RS04060
+0.3
1.0
hypothetical protein
compare
MMP
_RS06550
+0.3
1.6
AMP-binding protein
compare
MMP
_RS08770
+0.3
1.4
hypothetical protein
compare
MMP
_RS01155
+0.3
1.9
XRE family transcriptional regulator
compare
MMP
_RS05820
+0.3
1.6
RNA-binding transcriptional accessory protein
compare
MMP
_RS01460
+0.3
1.5
hypothetical protein
compare
MMP
_RS06480
+0.3
1.9
ABC transporter substrate-binding protein
compare
MMP
_RS00645
+0.3
2.1
iron ABC transporter permease
compare
MMP
_RS05825
+0.3
0.8
peptidyl-prolyl cis-trans isomerase
compare
MMP
_RS00105
+0.3
1.3
hypothetical protein
compare
MMP
_RS06465
+0.3
1.9
NERD domain-containing protein
compare
MMP
_RS01060
+0.3
1.9
calcium/sodium antiporter
compare
MMP
_RS05470
+0.3
2.2
DUF523 and DUF1722 domain-containing protein
compare
MMP
_RS08290
+0.3
1.0
DNA-binding protein Alba
compare
MMP
_RS01420
+0.3
0.7
hypothetical protein
compare
MMP
_RS02510
+0.3
1.9
site-specific integrase
compare
MMP
_RS01965
+0.3
1.2
DUF1616 domain-containing protein
compare
MMP
_RS06525
+0.3
0.4
YciI family protein
compare
MMP
_RS00650
+0.3
1.5
ABC transporter ATP-binding protein
compare
MMP
_RS01540
+0.3
1.0
DUF504 domain-containing protein
compare
MMP
_RS05660
+0.3
2.0
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS00625
+0.3
1.8
hypothetical protein
compare
MMP
_RS05995
+0.3
1.9
FprA family A-type flavoprotein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in stress experiments