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Experiment set9IT032 for
Methanococcus maripaludis S2
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H2 McCas with 5 minute oxygen exposure
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS05975
+1.0
2.1
hypothetical protein
compare
MMP
_RS08265
+1.0
5.1
rubrerythrin
compare
MMP
_RS05675
+1.0
3.1
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS08310
+0.9
2.3
TMEM165/GDT1 family protein
compare
MMP
_RS00655
+0.8
3.0
hypothetical protein
compare
MMP
_RS08315
+0.8
2.4
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS08760
+0.8
2.5
hypothetical protein
compare
MMP
_RS08725
+0.8
0.7
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS00675
+0.8
0.9
nitroreductase family protein
compare
MMP
_RS00290
+0.8
3.6
hypothetical protein
compare
MMP
_RS07890
+0.8
2.5
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS00705
+0.8
2.2
hypothetical protein
compare
MMP
_RS02605
+0.8
0.9
MotA/TolQ/ExbB proton channel family protein
compare
MMP
_RS08390
+0.7
3.0
DUF5400 domain-containing protein
compare
MMP
_RS01580
+0.7
3.6
PQQ-binding-like beta-propeller repeat protein
compare
MMP
_RS06910
+0.7
4.5
RlmF-related methyltransferase
compare
MMP
_RS07620
+0.7
3.1
energy-coupling factor ABC transporter substrate-binding protein
compare
MMP
_RS08160
+0.7
3.5
EamA family transporter
compare
MMP
_RS02045
+0.7
1.4
tRNA-Met
compare
MMP
_RS08415
+0.7
1.7
radical SAM protein
compare
MMP
_RS00155
+0.7
3.6
heavy metal-binding domain-containing protein
compare
MMP
_RS07925
+0.7
2.7
haloacid dehalogenase
compare
MMP
_RS06305
+0.6
4.3
transporter substrate-binding domain-containing protein
compare
MMP
_RS08775
+0.6
2.5
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS02300
+0.6
2.3
NAD(P)H-dependent oxidoreductase
compare
MMP
_RS08835
+0.6
4.0
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS08325
+0.6
3.3
hypothetical protein
compare
MMP
_RS08640
+0.6
4.2
TIM barrel protein
compare
MMP
_RS06190
+0.6
4.4
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMP
_RS06155
+0.6
2.0
DUF4186 domain-containing protein
compare
MMP
_RS01630
+0.6
3.8
N-glycosylase/DNA lyase
compare
MMP
_RS07910
+0.6
2.7
NAD(P)H-hydrate dehydratase
compare
MMP
_RS08215
+0.6
2.1
DUF483 domain-containing protein
compare
MMP
_RS08235
+0.6
2.9
hypothetical protein
compare
MMP
_RS06495
+0.6
1.1
YkgJ family cysteine cluster protein
compare
MMP
_RS08455
+0.6
1.9
multiprotein bridging factor aMBF1
compare
MMP
_RS08470
+0.6
3.4
ATP-binding cassette domain-containing protein
compare
MMP
_RS04035
+0.6
1.9
hypothetical protein
compare
MMP
_RS08260
+0.5
3.5
DUF99 family protein
compare
MMP
_RS01055
+0.5
2.2
hypothetical protein
compare
MMP
_RS03340
+0.5
0.6
ABC transporter ATP-binding protein
compare
MMP
_RS08480
+0.5
3.9
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS00395
+0.5
1.1
MGMT family protein
compare
MMP
_RS00990
+0.5
1.7
hypothetical protein
compare
MMP
_RS06520
+0.5
3.2
DUF1786 domain-containing protein
compare
MMP
_RS03300
+0.5
0.5
TOBE domain-containing protein
compare
MMP
_RS07815
+0.5
0.8
DUF2120 domain-containing protein
compare
MMP
_RS08430
+0.5
2.6
HAD family hydrolase
compare
MMP
_RS09065
+0.5
4.1
hypothetical protein
compare
MMP
_RS05660
+0.5
3.2
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS08485
+0.5
3.2
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS03065
+0.5
1.5
AzlC family ABC transporter permease
compare
MMP
_RS09060
+0.5
3.9
hypothetical protein
compare
MMP
_RS00650
+0.5
2.9
ABC transporter ATP-binding protein
compare
MMP
_RS01570
+0.5
0.9
hypothetical protein
compare
MMP
_RS06965
+0.5
2.9
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS08380
+0.5
2.4
phosphatase PAP2 family protein
compare
MMP
_RS01455
+0.5
2.9
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS08205
+0.5
3.4
stage II sporulation protein M
compare
MMP
_RS09025
+0.5
0.8
hypothetical protein
compare
MMP
_RS06165
+0.5
3.0
ABC transporter permease
compare
MMP
_RS06905
+0.5
0.7
hypothetical protein
compare
MMP
_RS03215
+0.5
2.8
MBL fold metallo-hydrolase
compare
MMP
_RS07155
+0.5
2.4
MFS transporter
compare
MMP
_RS06585
+0.5
1.0
DMT family protein
compare
MMP
_RS01965
+0.5
2.6
DUF1616 domain-containing protein
compare
MMP
_RS06335
+0.5
1.7
HAD family hydrolase
compare
MMP
_RS05720
+0.5
1.6
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS00540
+0.5
1.7
PLP-dependent aminotransferase family protein
compare
MMP
_RS08280
+0.5
1.6
proteasome assembly chaperone family protein
compare
MMP
_RS00660
+0.5
3.1
alkaline phosphatase family protein
compare
MMP
_RS08085
+0.5
2.8
hypothetical protein
compare
MMP
_RS08245
+0.5
2.2
DUF4013 domain-containing protein
compare
MMP
_RS00345
+0.4
2.3
DUF2666 domain-containing protein
compare
MMP
_RS00400
+0.4
2.3
tributyrin esterase
compare
MMP
_RS02815
+0.4
1.6
hypothetical protein
compare
MMP
_RS08475
+0.4
2.5
ABC transporter permease
compare
MMP
_RS09050
+0.4
1.2
CAP domain-containing protein
compare
MMP
_RS07805
+0.4
2.1
ABC transporter permease
compare
MMP
_RS05470
+0.4
3.3
DUF523 and DUF1722 domain-containing protein
compare
MMP
_RS08130
+0.4
3.1
IGHMBP2 family helicase
compare
MMP
_RS08090
+0.4
2.1
hypothetical protein
compare
MMP
_RS03965
+0.4
1.2
hypothetical protein
compare
MMP
_RS06545
+0.4
2.0
ferredoxin family protein
compare
MMP
_RS08240
+0.4
2.1
methanogenesis marker 16 metalloprotein
compare
MMP
_RS07970
+0.4
1.0
hypothetical protein
compare
MMP
_RS01675
+0.4
0.9
hypothetical protein
compare
MMP
_RS07145
+0.4
2.7
AmmeMemoRadiSam system protein B
compare
MMP
_RS08770
+0.4
1.8
hypothetical protein
compare
MMP
_RS01115
+0.4
2.4
molybdopterin molybdotransferase MoeA
compare
MMP
_RS01320
+0.4
1.6
hypothetical protein
compare
MMP
_RS05990
+0.4
2.3
DsrE family protein
compare
MMP
_RS07095
+0.4
1.4
PspC domain-containing protein
compare
MMP
_RS08700
+0.4
2.4
hypothetical protein
compare
MMP
_RS00960
+0.4
1.8
iron export ABC transporter permease subunit FetB
compare
MMP
_RS06500
+0.4
2.4
ATP-binding protein
compare
MMP
_RS07150
+0.4
1.7
MTH895/ArsE family thioredoxin-like protein
compare
MMP
_RS03465
+0.4
0.6
adenine phosphoribosyltransferase
compare
MMP
_RS00145
+0.4
2.1
ATP-dependent Clp protease proteolytic subunit
compare
MMP
_RS01110
+0.4
0.9
FmdE family protein
compare
MMP
_RS00285
+0.4
2.1
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS08755
+0.4
2.7
sodium:solute symporter family protein
compare
MMP
_RS06745
+0.4
1.1
DUF2119 domain-containing protein
compare
MMP
_RS01525
+0.4
0.9
nucleoside-diphosphate kinase
compare
MMP
_RS07985
+0.4
2.5
nitroreductase family protein
compare
MMP
_RS07915
+0.4
1.6
DUF4870 domain-containing protein
compare
MMP
_RS01260
+0.4
1.9
HDIG domain-containing protein
compare
MMP
_RS08285
+0.4
1.7
serine/threonine protein kinase
compare
MMP
_RS06045
+0.4
2.5
DNA polymerase
compare
MMP
_RS05985
+0.4
0.5
hypothetical protein
compare
MMP
_RS04805
+0.4
2.9
chemotaxis response regulator protein-glutamate methylesterase
compare
MMP
_RS06150
+0.4
2.5
hypothetical protein
compare
MMP
_RS01475
+0.4
2.0
phosphosulfolactate synthase
compare
MMP
_RS07765
+0.4
1.7
sodium:alanine symporter family protein
compare
MMP
_RS07715
+0.4
2.3
YfcE family phosphodiesterase
compare
MMP
_RS06875
+0.4
1.9
FAD-dependent oxidoreductase
compare
MMP
_RS01060
+0.4
2.6
calcium/sodium antiporter
compare
MMP
_RS06440
+0.4
2.1
CBS domain-containing protein
compare
MMP
_RS00385
+0.4
2.2
P-II family nitrogen regulator
compare
MMP
_RS00640
+0.4
1.6
ABC transporter substrate-binding protein
compare
MMP
_RS08980
+0.4
1.5
hypothetical protein
compare
MMP
_RS08490
+0.4
2.7
hypothetical protein
compare
MMP
_RS00565
+0.4
1.8
CBS domain-containing protein
compare
MMP
_RS06375
+0.4
1.5
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS06320
+0.3
1.1
hypothetical protein
compare
MMP
_RS02500
+0.3
1.6
minichromosome maintenance protein MCM
compare
MMP
_RS08405
+0.3
1.7
MFS transporter
compare
MMP
_RS07595
+0.3
2.0
hypothetical protein
compare
MMP
_RS07855
+0.3
1.8
class I SAM-dependent methyltransferase
compare
MMP
_RS08250
+0.3
1.8
pyruvate kinase
compare
MMP
_RS03890
+0.3
2.1
DUF2540 domain-containing protein
compare
MMP
_RS00795
+0.3
2.5
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS00825
+0.3
1.2
fumarylacetoacetate hydrolase family protein
compare
MMP
_RS08575
+0.3
2.6
hypothetical protein
compare
MMP
_RS00295
+0.3
1.0
gamma carbonic anhydrase family protein
compare
MMP
_RS06735
+0.3
1.3
class I SAM-dependent rRNA methyltransferase
compare
MMP
_RS01065
+0.3
2.5
alpha/beta hydrolase
compare
MMP
_RS05665
+0.3
1.3
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS00630
+0.3
1.9
ECF transporter S component
compare
MMP
_RS05490
+0.3
0.9
IMPACT family protein
compare
MMP
_RS00770
+0.3
1.1
hypothetical protein
compare
MMP
_RS05780
+0.3
2.1
multidrug resistance efflux transporter family protein
compare
MMP
_RS04635
+0.3
2.2
GNAT family N-acetyltransferase
compare
MMP
_RS03130
+0.3
1.6
hypothetical protein
compare
MMP
_RS08395
+0.3
1.1
DsrE family protein
compare
MMP
_RS06080
+0.3
2.7
radical SAM protein
compare
MMP
_RS00955
+0.3
2.1
coenzyme gamma-F420-2:alpha-L-glutamate ligase
compare
MMP
_RS05900
+0.3
1.6
tetratricopeptide repeat protein
compare
MMP
_RS05940
+0.3
1.3
corrinoid protein
compare
MMP
_RS04815
+0.3
1.5
chemotaxis protein CheD
compare
MMP
_RS01100
+0.3
0.6
ABC transporter ATP-binding protein
compare
MMP
_RS00105
+0.3
1.6
hypothetical protein
compare
MMP
_RS00625
+0.3
1.6
hypothetical protein
compare
MMP
_RS01010
+0.3
1.4
DUF4352 domain-containing protein
compare
MMP
_RS06300
+0.3
1.7
ABC transporter substrate-binding protein
compare
MMP
_RS08500
+0.3
1.2
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS07835
+0.3
1.1
TldD/PmbA family protein
compare
MMP
_RS01120
+0.3
1.5
permease
compare
MMP
_RS01635
+0.3
1.1
thiamine pyrophosphate-dependent enzyme
compare
MMP
_RS01485
+0.3
1.6
right-handed parallel beta-helix repeat-containing protein
compare
MMP
_RS09035
+0.3
1.4
hypothetical protein
compare
MMP
_RS00280
+0.3
2.0
DUF2118 domain-containing protein
compare
MMP
_RS01155
+0.3
1.7
XRE family transcriptional regulator
compare
MMP
_RS00375
+0.3
2.0
ammonium transporter
compare
MMP
_RS05175
+0.3
1.3
hypothetical protein
compare
MMP
_RS07590
+0.3
1.9
hypothetical protein
compare
MMP
_RS01470
+0.3
1.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS00195
+0.3
2.6
DUF4013 domain-containing protein
compare
MMP
_RS09030
+0.3
1.4
hypothetical protein
compare
MMP
_RS06560
+0.3
1.3
hypothetical protein
compare
MMP
_RS04145
+0.3
0.6
hypothetical protein
compare
MMP
_RS01855
+0.3
1.9
2-hydroxyacyl-CoA dehydratase family protein
compare
MMP
_RS02745
+0.3
0.9
hypothetical protein
compare
MMP
_RS06550
+0.3
1.7
AMP-binding protein
compare
MMP
_RS07085
+0.3
1.4
ribonuclease HII
compare
MMP
_RS07675
+0.3
2.4
S-layer protein
compare
MMP
_RS02680
+0.3
1.3
ABC transporter permease
compare
MMP
_RS08350
+0.3
0.3
hypothetical protein
compare
MMP
_RS05820
+0.3
1.3
RNA-binding transcriptional accessory protein
compare
MMP
_RS02375
+0.3
1.6
hypothetical protein
compare
MMP
_RS05155
+0.3
1.7
hypothetical protein
compare
MMP
_RS01145
+0.3
1.5
ABC transporter ATP-binding protein
compare
MMP
_RS00545
+0.3
1.1
XRE family transcriptional regulator
compare
MMP
_RS02295
+0.3
1.8
TatD family hydrolase
compare
MMP
_RS05365
+0.3
0.6
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
MMP
_RS07640
+0.3
1.2
mechanosensitive ion channel family protein
compare
MMP
_RS01865
+0.3
0.5
GPR1/FUN34/YaaH family transporter
compare
MMP
_RS06140
+0.3
0.9
radical SAM protein
compare
MMP
_RS07650
+0.3
2.1
TldD/PmbA family protein
compare
MMP
_RS07100
+0.3
1.7
hypothetical protein
compare
MMP
_RS08945
+0.3
2.1
hypothetical protein
compare
MMP
_RS00450
+0.3
0.7
4Fe-4S binding protein
compare
MMP
_RS07345
+0.3
1.2
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS00430
+0.3
1.0
hypothetical protein
compare
MMP
_RS03235
+0.3
1.3
tRNA pseudouridine(13) synthase TruD
compare
MMP
_RS01625
+0.3
1.6
rubredoxin
compare
MMP
_RS06570
+0.3
0.6
DUF190 domain-containing protein
compare
MMP
_RS06185
+0.3
1.4
thermonuclease family protein
compare
MMP
_RS07555
+0.3
0.2
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS02825
+0.3
1.6
mechanosensitive ion channel family protein
compare
Specific Phenotypes
For 3 genes in this experiment