Experiment set9IT012 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS07860		+1.6	1.6	hypothetical protein
MMP_RS08775		+1.0	5.0	methanogenesis marker 9 domain-containing protein
MMP_RS08310		+1.0	2.6	TMEM165/GDT1 family protein
MMP_RS08455		+1.0	4.5	multiprotein bridging factor aMBF1
MMP_RS00675		+0.9	1.1	nitroreductase family protein
MMP_RS08315		+0.9	2.5	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS01570		+0.9	1.8	hypothetical protein
MMP_RS08265		+0.9	2.4	rubrerythrin
MMP_RS05365		+0.8	1.7	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
MMP_RS05975		+0.8	1.6	hypothetical protein
MMP_RS07905		+0.8	3.0	DUF3343 domain-containing protein
MMP_RS07840		+0.8	2.8	ribonuclease III
MMP_RS07925		+0.8	1.8	haloacid dehalogenase
MMP_RS03300		+0.8	0.8	TOBE domain-containing protein
MMP_RS07815		+0.8	1.3	DUF2120 domain-containing protein
MMP_RS01630		+0.8	4.7	N-glycosylase/DNA lyase
MMP_RS08275		+0.8	4.2	hypothetical protein
MMP_RS01685		+0.8	2.6	indolepyruvate oxidoreductase subunit beta
MMP_RS06335		+0.8	2.4	HAD family hydrolase
MMP_RS08160		+0.7	4.1	EamA family transporter
MMP_RS06910		+0.7	3.9	RlmF-related methyltransferase
MMP_RS08670		+0.7	3.2	metallophosphoesterase
MMP_RS08640		+0.7	3.9	TIM barrel protein
MMP_RS08500		+0.7	2.4	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS08705		+0.7	3.3	sulfopyruvate decarboxylase subunit beta
MMP_RS02805		+0.7	1.3	HEPN domain-containing protein
MMP_RS03065		+0.7	2.0	AzlC family ABC transporter permease
MMP_RS03490		+0.7	1.5	DUF2115 domain-containing protein
MMP_RS08755		+0.7	5.1	sodium:solute symporter family protein
MMP_RS01865		+0.7	1.4	GPR1/FUN34/YaaH family transporter
MMP_RS00990		+0.7	1.9	hypothetical protein
MMP_RS07155		+0.7	3.4	MFS transporter
MMP_RS08325		+0.7	4.6	hypothetical protein
MMP_RS08480		+0.7	4.8	molybdate ABC transporter substrate-binding protein
MMP_RS06905		+0.7	1.6	hypothetical protein
MMP_RS02790		+0.6	1.1	class III signal peptide-containing protein
MMP_RS02490		+0.6	1.2	hypothetical protein
MMP_RS08260		+0.6	4.0	DUF99 family protein
MMP_RS07915		+0.6	3.4	DUF4870 domain-containing protein
MMP_RS07775		+0.6	2.8	alanine dehydrogenase
MMP_RS01130		+0.6	4.2	flavoprotein
MMP_RS07850		+0.6	1.9	prephenate dehydratase
MMP_RS07985		+0.6	3.9	nitroreductase family protein
MMP_RS08250		+0.6	3.9	pyruvate kinase
MMP_RS07895		+0.6	2.1	cytochrome c
MMP_RS00155		+0.6	3.7	heavy metal-binding domain-containing protein
MMP_RS07765		+0.6	2.9	sodium:alanine symporter family protein
MMP_RS08430		+0.6	3.5	HAD family hydrolase
MMP_RS07890		+0.6	1.2	OB-fold nucleic acid binding domain-containing protein
MMP_RS08575		+0.6	4.5	hypothetical protein
MMP_RS08380		+0.6	2.7	phosphatase PAP2 family protein
MMP_RS01650		+0.6	0.6	sulfurtransferase TusA family protein
MMP_RS08835		+0.6	3.3	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS03340		+0.6	0.6	ABC transporter ATP-binding protein
MMP_RS07805		+0.6	3.1	ABC transporter permease
MMP_RS08490		+0.6	4.4	hypothetical protein
MMP_RS09035		+0.6	2.4	hypothetical protein
MMP_RS08085		+0.6	3.5	hypothetical protein
MMP_RS09065		+0.6	3.7	hypothetical protein
MMP_RS05660		+0.5	3.0	phosphate ABC transporter substrate-binding protein
MMP_RS00665		+0.5	2.0	hypothetical protein
MMP_RS08555		+0.5	1.6	hypothetical protein
MMP_RS07835		+0.5	3.0	TldD/PmbA family protein
MMP_RS08405		+0.5	3.5	MFS transporter
MMP_RS08700		+0.5	2.4	hypothetical protein
MMP_RS01620		+0.5	3.0	hypothetical protein
MMP_RS07910		+0.5	2.9	NAD(P)H-hydrate dehydratase
MMP_RS06710		+0.5	3.4	selenium-binding protein
MMP_RS01580		+0.5	2.8	PQQ-binding-like beta-propeller repeat protein
MMP_RS08750		+0.5	1.3	hypothetical protein
MMP_RS06520		+0.5	1.7	DUF1786 domain-containing protein
MMP_RS02300		+0.5	2.7	NAD(P)H-dependent oxidoreductase
MMP_RS06540		+0.5	1.2	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS02370		+0.5	2.4	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS09060		+0.5	3.7	hypothetical protein
MMP_RS06375		+0.5	1.8	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS07095		+0.5	1.6	PspC domain-containing protein
MMP_RS00290		+0.5	2.9	hypothetical protein
MMP_RS01455		+0.5	2.3	nickel pincer cofactor biosynthesis protein LarC
MMP_RS00655		+0.5	1.7	hypothetical protein
MMP_RS08205		+0.5	2.9	stage II sporulation protein M
MMP_RS06325		+0.5	0.9	hypothetical protein
MMP_RS09030		+0.5	3.1	hypothetical protein
MMP_RS07650		+0.5	3.2	TldD/PmbA family protein
MMP_RS04100		+0.5	1.6	hypothetical protein
MMP_RS08130		+0.5	3.1	IGHMBP2 family helicase
MMP_RS08235		+0.5	2.4	hypothetical protein
MMP_RS01635		+0.5	2.1	thiamine pyrophosphate-dependent enzyme
MMP_RS08080		+0.5	2.3	YchF/TatD family DNA exonuclease
MMP_RS07590		+0.5	2.4	hypothetical protein
MMP_RS06590		+0.5	1.1	GNAT family N-acetyltransferase
MMP_RS04015		+0.4	1.2	hypothetical protein
MMP_RS08470		+0.4	1.8	ATP-binding cassette domain-containing protein
MMP_RS07855		+0.4	2.4	class I SAM-dependent methyltransferase
MMP_RS07150		+0.4	2.5	MTH895/ArsE family thioredoxin-like protein
MMP_RS00545		+0.4	2.2	XRE family transcriptional regulator
MMP_RS00395		+0.4	0.9	MGMT family protein
MMP_RS06990		+0.4	2.1	CatB-related O-acetyltransferase
MMP_RS06305		+0.4	2.4	transporter substrate-binding domain-containing protein
MMP_RS03965		+0.4	1.2	hypothetical protein
MMP_RS07900		+0.4	1.2	YeeE/YedE family protein
MMP_RS00540		+0.4	2.2	PLP-dependent aminotransferase family protein
MMP_RS00565		+0.4	1.8	CBS domain-containing protein
MMP_RS05675		+0.4	1.5	phosphate ABC transporter ATP-binding protein PstB
MMP_RS03740		+0.4	1.6	indolepyruvate oxidoreductase subunit beta
MMP_RS08395		+0.4	1.6	DsrE family protein
MMP_RS04145		+0.4	0.9	hypothetical protein
MMP_RS09050		+0.4	1.5	CAP domain-containing protein
MMP_RS07100		+0.4	2.6	hypothetical protein
MMP_RS08770		+0.4	1.9	hypothetical protein
MMP_RS01055		+0.4	1.4	hypothetical protein
MMP_RS00650		+0.4	2.0	ABC transporter ATP-binding protein
MMP_RS00960		+0.4	1.9	iron export ABC transporter permease subunit FetB
MMP_RS07595		+0.4	2.4	hypothetical protein
MMP_RS06570		+0.4	1.1	DUF190 domain-containing protein
MMP_RS01855		+0.4	2.4	2-hydroxyacyl-CoA dehydratase family protein
MMP_RS01160		+0.4	1.5	DMT family transporter
MMP_RS01785		+0.4	1.8	hypothetical protein
MMP_RS08390		+0.4	1.4	DUF5400 domain-containing protein
MMP_RS05435		+0.4	1.8	5'/3'-nucleotidase SurE
MMP_RS08175		+0.4	1.7	7-cyano-7-deazaguanine synthase
MMP_RS08075		+0.4	1.7	DUF749 domain-containing protein
MMP_RS08290		+0.4	1.6	DNA-binding protein Alba
MMP_RS01990		+0.4	1.1	hypothetical protein
MMP_RS00795		+0.4	2.2	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS01435		+0.4	1.4	DMT family transporter
MMP_RS06965		+0.4	1.6	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS01145		+0.4	2.6	ABC transporter ATP-binding protein
MMP_RS04205		+0.4	1.9	carboxymuconolactone decarboxylase family protein
MMP_RS06075		+0.4	2.3	class I SAM-dependent methyltransferase
MMP_RS08285		+0.4	1.9	serine/threonine protein kinase
MMP_RS08090		+0.4	1.3	hypothetical protein
MMP_RS00660		+0.4	2.2	alkaline phosphatase family protein
MMP_RS08485		+0.4	1.8	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS03670		+0.4	1.2	DUF1890 domain-containing protein
MMP_RS06165		+0.4	2.1	ABC transporter permease
MMP_RS08830		+0.3	1.0	GTP-binding protein
MMP_RS08215		+0.3	0.8	DUF483 domain-containing protein
MMP_RS00430		+0.3	1.2	hypothetical protein
MMP_RS02470		+0.3	0.3	helix-turn-helix transcriptional regulator
MMP_RS03215		+0.3	2.3	MBL fold metallo-hydrolase
MMP_RS05720		+0.3	0.9	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS08990		+0.3	1.8	hypothetical protein
MMP_RS00085		+0.3	2.5	DNA cytosine methyltransferase
MMP_RS01460		+0.3	1.2	hypothetical protein
MMP_RS07085		+0.3	2.1	ribonuclease HII
MMP_RS02595		+0.3	0.5	putative zinc-binding protein
MMP_RS06300		+0.3	1.8	ABC transporter substrate-binding protein
MMP_RS01680		+0.3	2.2	phenylacetate--CoA ligase
MMP_RS02680		+0.3	1.4	ABC transporter permease
MMP_RS04060		+0.3	1.3	hypothetical protein
MMP_RS02695		+0.3	1.5	formylmethanofuran dehydrogenase subunit A
MMP_RS07885		+0.3	1.0	tripartite tricarboxylate transporter permease
MMP_RS06190		+0.3	2.0	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS00345		+0.3	1.6	DUF2666 domain-containing protein
MMP_RS05695		+0.3	1.5	phospholipase D-like domain-containing protein
MMP_RS01420		+0.3	0.8	hypothetical protein
MMP_RS01060		+0.3	1.9	calcium/sodium antiporter
MMP_RS01105		+0.3	1.3	hypothetical protein
MMP_RS06500		+0.3	1.6	ATP-binding protein
MMP_RS03840		+0.3	1.3	hypothetical protein
MMP_RS00975		+0.3	1.7	HD domain-containing protein
MMP_RS05835		+0.3	0.3	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS05980		+0.3	2.2	ferritin
MMP_RS07680		+0.3	1.1	DUF366 family protein
MMP_RS00185		+0.3	2.0	potassium channel protein
MMP_RS02745		+0.3	0.9	hypothetical protein
MMP_RS01965		+0.3	1.6	DUF1616 domain-containing protein
MMP_RS07970		+0.3	0.7	hypothetical protein
MMP_RS05970		+0.3	1.5	class II SORL domain-containing protein
MMP_RS02985		+0.3	1.3	hypothetical protein
MMP_RS08410		+0.3	1.2	DUF169 domain-containing protein
MMP_RS01645		+0.3	0.9	SWIM zinc finger family protein
MMP_RS06545		+0.3	1.2	ferredoxin family protein
MMP_RS02690		+0.3	1.4	FmdE family protein
MMP_RS05825		+0.3	1.0	peptidyl-prolyl cis-trans isomerase
MMP_RS06005		+0.3	1.4	heavy-metal-associated domain-containing protein
MMP_RS07715		+0.3	1.6	YfcE family phosphodiesterase
MMP_RS00800		+0.3	2.4	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01485		+0.3	1.6	right-handed parallel beta-helix repeat-containing protein
MMP_RS04830		+0.3	2.2	chemotaxis protein CheC
MMP_RS04190		+0.3	2.1	hypothetical protein
MMP_RS04635		+0.3	1.9	GNAT family N-acetyltransferase
MMP_RS00105		+0.3	1.7	hypothetical protein
MMP_RS07800		+0.3	1.8	ATP-binding cassette domain-containing protein
MMP_RS06745		+0.3	0.9	DUF2119 domain-containing protein
MMP_RS03885		+0.3	1.8	tyrosine-type recombinase/integrase
MMP_RS08400		+0.3	0.8	MJ0307 family thioredoxin
MMP_RS01625		+0.3	1.7	rubredoxin
MMP_RS00940		+0.3	1.5	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS02380		+0.3	1.5	ATP-binding protein
MMP_RS01200		+0.3	1.1	hypothetical protein
MMP_RS02590		+0.3	1.3	low molecular weight phosphatase family protein
MMP_RS00335		+0.3	1.2	5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
MMP_RS05470		+0.3	1.8	DUF523 and DUF1722 domain-containing protein
MMP_RS08385		+0.3	1.8	ABC transporter substrate-binding protein
MMP_RS08475		+0.3	1.4	ABC transporter permease
MMP_RS07795		+0.3	1.8	site-2 protease family protein
MMP_RS08945		+0.3	1.8	hypothetical protein
MMP_RS01115		+0.3	1.3	molybdopterin molybdotransferase MoeA

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium sulfide nonahydrate across organisms