Experiment set8S554 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Novobiocin sodium salt 0.0125 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS04875 -4.8 -0.6 tRNA-Lys compare
MMJJ_RS04485 -4.1 -5.1 riboflavin synthase compare
MMJJ_RS08810 -4.0 -0.5 DUF4040 domain-containing protein compare
MMJJ_RS09295 -4.0 -0.5 hypothetical protein compare
MMJJ_RS07960 -3.9 -1.2 quinolinate synthase NadA compare
MMJJ_RS01810 -3.6 -0.8 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS07360 -3.6 -0.8 TIGR00269 family protein compare
MMJJ_RS03250 -3.6 -1.7 DUF2116 family Zn-ribbon domain-containing protein compare
MMJJ_RS00050 -3.5 -7.8 AAA family ATPase compare
MMJJ_RS05065 -3.4 -2.1 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS00045 -3.4 -12.6 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS00035 -3.4 -13.9 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS00065 -3.4 -8.7 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS00070 -3.3 -2.0 CooT family nickel-binding protein compare
MMJJ_RS00055 -3.3 -8.6 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS06600 -3.3 -1.0 DUF555 domain-containing protein compare
MMJJ_RS00080 -3.3 -13.5 DUF166 domain-containing protein compare
MMJJ_RS00060 -3.3 -14.8 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS03490 -3.3 -0.9 ribonuclease VapC compare
MMJJ_RS03185 -3.3 -0.9 alanine--tRNA ligase compare
MMJJ_RS00450 -3.3 -0.9 DUF126 domain-containing protein compare
MMJJ_RS00075 -3.2 -10.0 AAA family ATPase compare
MMJJ_RS00580 -3.2 -0.7 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS03810 -3.1 -1.0 AIR synthase-related protein compare
MMJJ_RS01405 -3.1 -0.6 proline--tRNA ligase compare
MMJJ_RS05575 -3.1 -1.3 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS07955 -3.1 -9.1 ThiF family adenylyltransferase compare
MMJJ_RS06660 -3.1 -7.1 DUF1188 domain-containing protein compare
MMJJ_RS07970 -3.1 -1.2 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS00570 -3.0 -0.7 ribonuclease P compare
MMJJ_RS00040 -3.0 -6.7 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS03110 -3.0 -1.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS07380 -2.9 -5.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS09375 -2.9 -0.7 hypothetical protein compare
MMJJ_RS05280 -2.9 -0.5 hypothetical protein compare
MMJJ_RS07975 -2.9 -6.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS05380 -2.9 -0.5 hypothetical protein compare
MMJJ_RS00355 -2.8 -1.0 ribonuclease P protein component 4 compare
MMJJ_RS07245 -2.8 -1.5 amidohydrolase family protein compare
MMJJ_RS04760 -2.8 -12.6 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS07950 -2.8 -1.0 4Fe-4S binding protein compare
MMJJ_RS04180 -2.8 -1.5 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS08535 -2.7 -1.0 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS04755 -2.7 -9.6 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS02200 -2.7 -4.8 chorismate pyruvate-lyase family protein compare
MMJJ_RS04720 -2.7 -1.0 IMP dehydrogenase compare
MMJJ_RS04750 -2.7 -7.6 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS03230 -2.7 -1.9 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS00285 -2.7 -10.3 UPF0254 family protein compare
MMJJ_RS08325 -2.7 -0.8 glycosyltransferase family 2 protein compare
MMJJ_RS00210 -2.6 -0.8 DUF530 family protein compare
MMJJ_RS07000 -2.6 -0.7 TrkH family potassium uptake protein compare
MMJJ_RS08500 -2.6 -4.0 L-sulfolactate dehydrogenase compare
MMJJ_RS01690 -2.6 -1.5 methanogenesis marker 12 protein compare
MMJJ_RS00935 -2.6 -7.6 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS01880 -2.6 -1.7 RlmE family RNA methyltransferase compare
MMJJ_RS07505 -2.6 -0.6 DNA-directed RNA polymerase subunit K compare
MMJJ_RS06695 -2.6 -0.9 amidohydrolase compare
MMJJ_RS08840 -2.6 -1.8 calcium/sodium antiporter compare
MMJJ_RS05935 -2.6 -0.8 Era-like GTP-binding protein compare
MMJJ_RS06915 -2.5 -10.6 helix-turn-helix domain-containing protein compare
MMJJ_RS05360 -2.5 -4.1 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS05535 -2.5 -8.9 hypothetical protein compare
MMJJ_RS06110 -2.5 -0.8 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS08625 -2.5 -3.0 magnesium/cobalt transporter CorA compare
MMJJ_RS06750 -2.5 -0.7 homoaconitase large subunit compare
MMJJ_RS00475 -2.5 -0.7 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS03965 -2.5 -0.6 DNA-directed RNA polymerase subunit L compare
MMJJ_RS07410 -2.4 -1.4 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS07190 -2.4 -1.9 RtcB family protein compare
MMJJ_RS03225 -2.4 -0.8 4Fe-4S binding protein compare
MMJJ_RS05190 -2.4 -4.4 gamma carbonic anhydrase family protein compare
MMJJ_RS06910 -2.4 -1.5 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS03920 -2.4 -9.9 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS03245 -2.3 -0.4 UMP kinase compare
MMJJ_RS07875 -2.3 -0.8 FAD-dependent oxidoreductase compare
MMJJ_RS01830 -2.3 -0.9 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS05995 -2.3 -0.7 ATP-binding cassette domain-containing protein compare
MMJJ_RS08010 -2.3 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS09055 -2.3 -7.0 NFACT family protein compare
MMJJ_RS03765 -2.3 -4.4 hypothetical protein compare
MMJJ_RS02045 -2.3 -1.0 molybdenum cofactor guanylyltransferase compare
MMJJ_RS03125 -2.2 -1.0 GMC oxidoreductase compare
MMJJ_RS08935 -2.2 -0.4 TIGR00288 family NYN domain-containing protein compare
MMJJ_RS06380 -2.2 -1.0 signal recognition particle protein Srp54 compare
MMJJ_RS06875 -2.2 -1.1 hypothetical protein compare
MMJJ_RS08585 -2.2 -4.3 M42 family metallopeptidase compare
MMJJ_RS06725 -2.2 -8.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS07470 -2.2 -1.0 50S ribosome-binding GTPase compare
MMJJ_RS08020 -2.2 -6.0 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06760 -2.2 -1.1 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS04475 -2.2 -1.9 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS01360 -2.1 -0.7 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS04150 -2.1 -1.1 DUF5379 domain-containing protein compare
MMJJ_RS03095 -2.1 -1.0 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS09175 -2.1 -0.8 anthranilate synthase component I compare
MMJJ_RS04980 -2.1 -2.1 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS08380 -2.1 -2.1 hypothetical protein compare
MMJJ_RS07035 -2.1 -0.9 glycosyl transferase compare
MMJJ_RS06390 -2.1 -0.5 NADPH-dependent F420 reductase compare
MMJJ_RS02040 -2.1 -0.9 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS08080 -2.1 -5.9 TIGR00300 family protein compare
MMJJ_RS00215 -2.1 -0.7 CCA tRNA nucleotidyltransferase compare
MMJJ_RS00600 -2.0 -1.1 hydroxymethylbilane synthase compare
MMJJ_RS07415 -2.0 -1.4 polyprenyl diphosphate synthase compare
MMJJ_RS06175 -2.0 -0.6 DUF1743 domain-containing protein compare
MMJJ_RS06835 -2.0 -7.2 4Fe-4S binding protein compare
MMJJ_RS07705 -2.0 -0.8 GTP-binding protein EngB compare
MMJJ_RS01355 -2.0 -0.9 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS05560 -2.0 -2.5 30S ribosomal protein S27e compare
MMJJ_RS05655 -2.0 -5.0 HisA/HisF family protein compare
MMJJ_RS06155 -2.0 -2.7 phosphatidylglycerophosphatase A compare
MMJJ_RS04800 -2.0 -2.7 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS03270 -1.9 -0.9 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS02855 -1.9 -5.6 DEAD/DEAH box helicase compare
MMJJ_RS05195 -1.9 -2.8 hypothetical protein compare
MMJJ_RS03875 -1.9 -0.8 CBS domain-containing protein compare
MMJJ_RS03655 -1.9 -2.5 replication factor C large subunit compare
MMJJ_RS06665 -1.9 -2.4 DUF3236 domain-containing protein compare
MMJJ_RS05445 -1.9 -0.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS01285 -1.9 -3.2 CopG family ribbon-helix-helix protein compare
MMJJ_RS04200 -1.9 -2.1 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS03190 -1.9 -0.7 phosphopyruvate hydratase compare
MMJJ_RS05135 -1.8 -0.7 50S ribosomal protein L18Ae compare
MMJJ_RS04700 -1.8 -3.5 deoxyhypusine synthase compare
MMJJ_RS01820 -1.8 -2.6 MJ1244 family protein compare
MMJJ_RS05415 -1.8 -0.5 hypothetical protein compare
MMJJ_RS06375 -1.8 -1.9 UbiX family flavin prenyltransferase compare
MMJJ_RS07155 -1.8 -6.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS07345 -1.8 -4.6 homocysteine biosynthesis protein compare
MMJJ_RS03760 -1.8 -0.7 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS04975 -1.8 -0.5 glycosyltransferase family 4 protein compare
MMJJ_RS09265 -1.8 -1.4 hypothetical protein compare
MMJJ_RS00550 -1.8 -5.4 AIR synthase-related protein compare
MMJJ_RS01500 -1.8 -4.0 transcriptional regulator compare
MMJJ_RS08060 -1.7 -4.7 DNA repair and recombination protein RadA compare
MMJJ_RS08660 -1.7 -1.4 acetylornithine transaminase compare
MMJJ_RS04790 -1.7 -1.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS08335 -1.7 -0.7 ABC transporter ATP-binding protein compare
MMJJ_RS05650 -1.7 -0.6 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS00525 -1.7 -1.0 Dabb family protein compare
MMJJ_RS04685 -1.7 -4.0 carbamoyltransferase HypF compare
MMJJ_RS08430 -1.7 -2.8 small nuclear ribonucleoprotein compare
MMJJ_RS00205 -1.7 -2.1 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS06180 -1.7 -1.0 tryptophan--tRNA ligase compare
MMJJ_RS09035 -1.7 -2.6 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS06260 -1.6 -3.0 6-carboxyhexanoate--CoA ligase compare
MMJJ_RS06635 -1.6 -8.1 4Fe-4S binding protein compare
MMJJ_RS08130 -1.6 -0.5 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS05590 -1.6 -0.8 homoserine dehydrogenase compare
MMJJ_RS01415 -1.6 -0.5 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS04615 -1.6 -1.9 methanogenesis marker 3 protein compare
MMJJ_RS06250 -1.6 -0.6 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS06265 -1.6 -6.1 8-amino-7-oxononanoate synthase compare
MMJJ_RS03005 -1.6 -1.0 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS01665 -1.6 -5.3 archease compare
MMJJ_RS01875 -1.6 -2.8 global nitrogen regulator NrpR compare
MMJJ_RS00220 -1.6 -2.7 UPF0058 family protein compare
MMJJ_RS07425 -1.5 -5.2 MBL fold metallo-hydrolase compare
MMJJ_RS01155 -1.5 -3.2 hypothetical protein compare
MMJJ_RS02090 -1.5 -2.3 tyramine--L-glutamate ligase compare
MMJJ_RS00195 -1.5 -1.2 precorrin-3B C(17)-methyltransferase compare
MMJJ_RS00400 -1.5 -2.8 tautomerase family protein compare
MMJJ_RS01200 -1.5 -0.6 PRC-barrel domain-containing protein compare
MMJJ_RS01650 -1.5 -8.4 acetolactate synthase large subunit compare
MMJJ_RS04730 -1.5 -1.2 tyrosine decarboxylase MfnA compare
MMJJ_RS00785 -1.5 -1.3 hypothetical protein compare
MMJJ_RS09050 -1.5 -2.3 hypothetical protein compare
MMJJ_RS07275 -1.5 -0.6 formate--phosphoribosylaminoimidazolecarboxamide ligase compare
MMJJ_RS06715 -1.5 -5.9 lactaldehyde dehydrogenase compare
MMJJ_RS05155 -1.5 -1.8 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS01960 -1.5 -2.9 glycosyltransferase family 2 protein compare
MMJJ_RS06270 -1.4 -3.6 dethiobiotin synthase compare
MMJJ_RS06705 -1.4 -2.1 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS09085 -1.4 -5.6 minichromosome maintenance protein MCM compare
MMJJ_RS03115 -1.4 -2.4 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS07160 -1.4 -8.3 M20 family metallo-hydrolase compare
MMJJ_RS04340 -1.4 -2.0 hypothetical protein compare
MMJJ_RS03585 -1.4 -0.4 methanogenesis marker 6 protein compare
MMJJ_RS05170 -1.4 -5.1 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS08135 -1.4 -1.9 30S ribosomal protein S6e compare
MMJJ_RS03785 -1.4 -0.9 hypothetical protein compare
MMJJ_RS07590 -1.4 -5.0 flap endonuclease-1 compare
MMJJ_RS03320 -1.4 -3.1 hypothetical protein compare
MMJJ_RS08025 -1.4 -2.1 hypothetical protein compare
MMJJ_RS01750 -1.4 -0.6 ferrous iron transport protein A compare
MMJJ_RS02915 -1.4 -2.4 hypothetical protein compare
MMJJ_RS05260 -1.3 -2.1 ATP-grasp domain-containing protein compare
MMJJ_RS07980 -1.3 -6.3 biotin synthase BioB compare
MMJJ_RS01350 -1.3 -2.7 sodium:proton antiporter compare
MMJJ_RS04985 -1.3 -1.1 glutamyl-tRNA reductase compare
MMJJ_RS03620 -1.3 -1.7 DUF2097 domain-containing protein compare
MMJJ_RS06140 -1.3 -4.2 RimK family alpha-L-glutamate ligase compare
MMJJ_RS09135 -1.3 -3.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMJJ_RS06255 -1.3 -2.9 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS09130 -1.3 -0.6 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS03360 -1.3 -0.7 hypothetical protein compare
MMJJ_RS07825 -1.3 -2.5 YciI family protein compare
MMJJ_RS05070 -1.3 -0.5 DNA primase catalytic subunit PriS compare
MMJJ_RS03580 -1.3 -0.8 TIGR00303 family protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Novobiocin sodium salt in Methanococcus maripaludis JJ

For stress Novobiocin sodium salt across organisms