Experiment set8S554 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Novobiocin sodium salt 0.0125 mM

200 most detrimental genes:

  gene name fitness t score description  
MMJJ_RS05160 +2.8 3.7 RNA-binding protein compare
MMJJ_RS03725 +2.7 4.8 sulfurtransferase TusA family protein compare
MMJJ_RS07650 +2.4 17.0 formate/nitrite transporter family protein compare
MMJJ_RS04005 +2.4 10.7 acetate--CoA ligase family protein compare
MMJJ_RS06945 +2.2 12.6 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMJJ_RS08065 +2.2 1.6 precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT compare
MMJJ_RS07660 +2.1 9.8 carbonic anhydrase compare
MMJJ_RS07635 +2.0 10.4 response regulator transcription factor compare
MMJJ_RS04145 +1.9 7.9 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS01070 +1.9 2.1 PadR family transcriptional regulator compare
MMJJ_RS01915 +1.9 6.8 precorrin-6A reductase compare
MMJJ_RS00440 +1.8 7.5 selenide, water dikinase SelD compare
MMJJ_RS07680 +1.8 6.2 glucose-6-phosphate isomerase compare
MMJJ_RS07185 +1.8 2.2 DUF371 domain-containing protein compare
MMJJ_RS07640 +1.7 14.4 cache domain-containing protein compare
MMJJ_RS08710 +1.7 4.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMJJ_RS07280 +1.6 4.3 phosphomannomutase/phosphoglucomutase compare
MMJJ_RS06700 +1.6 2.5 L-seryl-tRNA(Sec) kinase compare
MMJJ_RS05530 +1.6 3.1 roadblock/LC7 domain-containing protein compare
MMJJ_RS03605 +1.5 3.1 TIGR00297 family protein compare
MMJJ_RS06950 +1.5 5.0 4-demethylwyosine synthase TYW1 compare
MMJJ_RS06050 +1.5 7.2 molybdopterin molybdotransferase MoeA compare
MMJJ_RS00500 +1.4 2.5 GNAT family N-acetyltransferase compare
MMJJ_RS05770 +1.4 1.4 flagellar protein D compare
MMJJ_RS07175 +1.3 6.6 DEAD/DEAH box helicase compare
MMJJ_RS05785 +1.3 5.6 flagellin compare
MMJJ_RS08725 +1.3 5.2 flippase compare
MMJJ_RS02190 +1.2 7.9 molybdopterin biosynthesis protein compare
MMJJ_RS07405 +1.2 2.1 histone family protein compare
MMJJ_RS07850 +1.2 5.6 ATP-binding protein compare
MMJJ_RS06675 +1.2 4.2 TIGR01212 family radical SAM protein compare
MMJJ_RS05870 +1.2 2.1 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMJJ_RS07455 +1.2 2.9 coenzyme F420-reducing hydrogenase, FrhD protein compare
MMJJ_RS04195 +1.2 3.1 XTP/dITP diphosphatase compare
MMJJ_RS06975 +1.1 1.8 protein translocase SEC61 complex subunit gamma compare
MMJJ_RS02120 +1.1 2.2 DJ-1/PfpI family protein compare
MMJJ_RS08125 +1.1 4.6 DNA double-strand break repair nuclease NurA compare
MMJJ_RS05540 +1.1 8.0 LysR family transcriptional regulator compare
MMJJ_RS06535 +1.1 4.8 UPF0104 family protein compare
MMJJ_RS09190 +1.1 0.7 tryptophan synthase subunit beta compare
MMJJ_RS05030 +1.1 4.6 orotate phosphoribosyltransferase-like protein compare
MMJJ_RS01375 +1.1 3.8 tetrahydromethanopterin:alpha-L-glutamate ligase compare
MMJJ_RS04450 +1.0 3.1 diphthamide biosynthesis enzyme Dph2 compare
MMJJ_RS07440 +1.0 3.0 metallophosphoesterase compare
MMJJ_RS06925 +1.0 0.8 GMP synthase subunit A compare
MMJJ_RS05765 +1.0 0.4 flagellar protein E compare
MMJJ_RS05720 +1.0 0.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS04215 +1.0 4.2 DMT family transporter compare
MMJJ_RS07435 +1.0 4.7 SMC family ATPase compare
MMJJ_RS03835 +1.0 1.6 DUF504 domain-containing protein compare
MMJJ_RS01815 +1.0 1.2 DUF134 domain-containing protein compare
MMJJ_RS06200 +1.0 0.9 phosphoglycerate dehydrogenase compare
MMJJ_RS06290 +1.0 3.1 DUF749 domain-containing protein compare
MMJJ_RS09230 +1.0 2.4 hypothetical protein compare
MMJJ_RS08520 +1.0 1.1 peptidylprolyl isomerase compare
MMJJ_RS01975 +0.9 2.6 diphthine synthase compare
MMJJ_RS03575 +0.9 2.5 NUDIX hydrolase compare
MMJJ_RS05745 +0.9 3.8 type II/IV secretion system ATPase subunit compare
MMJJ_RS05400 +0.9 2.1 CoA-binding protein compare
MMJJ_RS05685 +0.9 2.8 class III signal peptide-containing protein compare
MMJJ_RS04575 +0.9 2.6 DUF116 domain-containing protein compare
MMJJ_RS02275 +0.9 1.9 nucleotidyltransferase domain-containing protein compare
MMJJ_RS03175 +0.9 3.0 zinc metalloprotease HtpX compare
MMJJ_RS05740 +0.9 3.7 archaellar assembly protein FlaJ compare
MMJJ_RS02140 +0.9 3.0 preflagellin peptidase FlaK compare
MMJJ_RS03540 +0.9 1.7 TIGR00289 family protein compare
MMJJ_RS03495 +0.9 2.1 hypothetical protein compare
MMJJ_RS01745 +0.9 1.7 metal-dependent transcriptional regulator compare
MMJJ_RS08195 +0.8 1.9 DUF4186 domain-containing protein compare
MMJJ_RS04465 +0.8 3.2 MTAP family purine nucleoside phosphorylase compare
MMJJ_RS08870 +0.8 0.5 2-isopropylmalate synthase compare
MMJJ_RS08785 +0.8 2.3 D-sedoheptulose 7-phosphate isomerase compare
MMJJ_RS08750 +0.8 3.6 glycosyltransferase compare
MMJJ_RS02195 +0.8 3.8 AmmeMemoRadiSam system radical SAM enzyme compare
MMJJ_RS01590 +0.8 0.7 adenine phosphoribosyltransferase compare
MMJJ_RS00180 +0.8 2.7 DNA topoisomerase I compare
MMJJ_RS06460 +0.8 2.8 cytochrome c compare
MMJJ_RS05750 +0.8 2.6 flagellar accessory protein FlaH compare
MMJJ_RS06730 +0.8 2.0 ATP-binding cassette domain-containing protein compare
MMJJ_RS04955 +0.8 2.4 tRNA pseudouridine(54/55) synthase Pus10 compare
MMJJ_RS00665 +0.8 3.6 lysine 2,3-aminomutase compare
MMJJ_RS07205 +0.8 1.5 MTH895/ArsE family thioredoxin-like protein compare
MMJJ_RS00745 +0.8 1.5 hypothetical protein compare
MMJJ_RS06995 +0.8 3.1 2-phosphoglycerate kinase compare
MMJJ_RS01945 +0.8 2.3 cell division ATPase MinD compare
MMJJ_RS05790 +0.8 1.9 flagellin compare
MMJJ_RS09245 +0.8 1.9 hypothetical protein compare
MMJJ_RS00485 +0.8 1.7 tetratricopeptide repeat protein compare
MMJJ_RS08615 +0.7 2.1 oligosaccharide repeat unit polymerase family protein compare
MMJJ_RS02055 +0.7 3.9 GTP 3',8-cyclase MoaA compare
MMJJ_RS05755 +0.7 2.8 flagellar protein G compare
MMJJ_RS00530 +0.7 3.1 cobalt ECF transporter T component CbiQ compare
MMJJ_RS07030 +0.7 4.4 hypothetical protein compare
MMJJ_RS07905 +0.7 2.6 DUF89 domain-containing protein compare
MMJJ_RS08630 +0.7 1.8 signal recognition particle subunit SRP19/SEC65 family protein compare
MMJJ_RS07490 +0.7 1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMJJ_RS05495 +0.7 2.8 MinD/ParA family protein compare
MMJJ_RS01270 +0.7 2.2 4Fe-4S binding protein compare
MMJJ_RS08320 +0.7 0.5 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS01140 +0.7 2.0 helix-turn-helix domain-containing protein compare
MMJJ_RS04345 +0.7 1.1 DUF2080 family transposase-associated protein compare
MMJJ_RS01470 +0.7 1.3 Hsp20/alpha crystallin family protein compare
MMJJ_RS07240 +0.7 3.7 MBL fold metallo-hydrolase compare
MMJJ_RS04660 +0.7 2.4 hypoxanthine/guanine phosphoribosyltransferase compare
MMJJ_RS01515 +0.7 1.7 DUF2178 domain-containing protein compare
MMJJ_RS00870 +0.7 1.7 F420-nonreducing hydrogenase compare
MMJJ_RS07865 +0.7 1.8 zinc ribbon domain-containing protein compare
MMJJ_RS01505 +0.7 1.4 DUF2124 domain-containing protein compare
MMJJ_RS04585 +0.6 2.1 phenylacetate--CoA ligase compare
MMJJ_RS02890 +0.6 2.6 ATP-binding protein compare
MMJJ_RS07655 +0.6 3.8 hypothetical protein compare
MMJJ_RS06785 +0.6 2.1 RNA ligase partner protein compare
MMJJ_RS06295 +0.6 2.3 DUF2096 family protein compare
MMJJ_RS07025 +0.6 1.7 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMJJ_RS02340 +0.6 2.3 SAM-dependent methyltransferase compare
MMJJ_RS03595 +0.6 1.4 hypothetical protein compare
MMJJ_RS03410 +0.6 0.9 hypothetical protein compare
MMJJ_RS01530 +0.6 0.6 YwbE family protein compare
MMJJ_RS06575 +0.6 0.9 prephenate dehydrogenase compare
MMJJ_RS08260 +0.6 2.4 ABC transporter ATP-binding protein compare
MMJJ_RS03515 +0.6 1.8 GPR1/FUN34/YaaH family transporter compare
MMJJ_RS00695 +0.6 2.3 P-II family nitrogen regulator compare
MMJJ_RS01855 +0.6 2.3 MBL fold metallo-hydrolase compare
MMJJ_RS06395 +0.6 3.0 sugar phosphate isomerase/epimerase compare
MMJJ_RS08865 +0.6 2.2 class IV adenylate cyclase compare
MMJJ_RS04250 +0.6 1.8 thioredoxin family protein compare
MMJJ_RS06365 +0.6 3.8 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMJJ_RS03355 +0.6 2.2 hypothetical protein compare
MMJJ_RS04580 +0.6 2.8 2-phosphosulfolactate phosphatase compare
MMJJ_RS01055 +0.6 0.9 hypothetical protein compare
MMJJ_RS02115 +0.6 1.7 class I SAM-dependent methyltransferase family protein compare
MMJJ_RS05970 +0.6 0.6 MJ0307 family thioredoxin compare
MMJJ_RS00960 +0.6 1.9 flavodoxin family protein compare
MMJJ_RS04500 +0.6 2.1 hypothetical protein compare
MMJJ_RS00405 +0.6 1.8 flavodoxin family protein compare
MMJJ_RS08655 +0.6 2.3 phospholipase D-like domain-containing protein compare
MMJJ_RS01040 +0.6 1.2 DUF4013 domain-containing protein compare
MMJJ_RS04680 +0.6 1.9 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMJJ_RS05595 +0.5 0.6 hypothetical protein compare
MMJJ_RS01565 +0.5 1.2 TIGR00267 family protein compare
MMJJ_RS04855 +0.5 2.1 ECF transporter S component compare
MMJJ_RS08830 +0.5 0.6 hypothetical protein compare
MMJJ_RS08730 +0.5 2.0 glycosyltransferase family 4 protein compare
MMJJ_RS00320 +0.5 1.0 chemotaxis protein CheD compare
MMJJ_RS04515 +0.5 2.8 HD domain-containing protein compare
MMJJ_RS06340 +0.5 0.7 coenzyme-B sulfoethylthiotransferase subunit alpha compare
MMJJ_RS01300 +0.5 1.8 MarR family transcriptional regulator compare
MMJJ_RS06000 +0.5 1.2 cation:proton antiporter subunit C compare
MMJJ_RS04620 +0.5 0.6 homocitrate synthase family protein compare
MMJJ_RS03830 +0.5 1.5 CBS domain-containing protein compare
MMJJ_RS01510 +0.5 2.1 ATP-binding protein compare
MMJJ_RS09220 +0.5 1.8 cupredoxin family copper-binding protein compare
MMJJ_RS08005 +0.5 3.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS05760 +0.5 2.4 flagellar protein F compare
MMJJ_RS02345 +0.5 2.1 ATP-binding protein compare
MMJJ_RS03450 +0.5 1.4 hypothetical protein compare
MMJJ_RS03775 +0.5 0.7 50S ribosomal protein L15e compare
MMJJ_RS06455 +0.5 2.3 YeeE/YedE family protein compare
MMJJ_RS06500 +0.5 1.4 class I SAM-dependent methyltransferase compare
MMJJ_RS01800 +0.5 1.7 ADP-ribosylglycohydrolase family protein compare
MMJJ_RS08225 +0.5 0.7 peptidylprolyl isomerase compare
MMJJ_RS09390 +0.5 0.6 hypothetical protein compare
MMJJ_RS07965 +0.5 1.4 hypothetical protein compare
MMJJ_RS05140 +0.5 0.9 DUF2666 domain-containing protein compare
MMJJ_RS07800 +0.5 2.3 AMP-binding protein compare
MMJJ_RS03290 +0.5 2.4 amidohydrolase compare
MMJJ_RS03625 +0.5 2.0 DUF63 family protein compare
MMJJ_RS07775 +0.5 1.4 fluoride efflux transporter CrcB compare
MMJJ_RS05815 +0.5 1.1 hypothetical protein compare
MMJJ_RS00630 +0.5 2.0 betaine/proline/choline family ABC transporter ATP-binding protein compare
MMJJ_RS02985 +0.5 2.1 MBL fold metallo-hydrolase compare
MMJJ_RS08310 +0.5 1.2 ZIP family metal transporter compare
MMJJ_RS03105 +0.5 3.0 methyl-accepting chemotaxis protein compare
MMJJ_RS00430 +0.5 0.5 ribonuclease Z compare
MMJJ_RS08775 +0.5 2.1 PfkB family carbohydrate kinase compare
MMJJ_RS09250 +0.5 0.6 hypothetical protein compare
MMJJ_RS03750 +0.5 1.8 rubredoxin compare
MMJJ_RS08930 +0.5 1.6 5'/3'-nucleotidase SurE compare
MMJJ_RS07765 +0.5 0.9 DMT family protein compare
MMJJ_RS01770 +0.5 1.0 TOBE domain-containing protein compare
MMJJ_RS00880 +0.5 1.9 coenzyme F420 hydrogenase subunit alpha compare
MMJJ_RS07010 +0.4 1.3 preprotein translocase subunit Sec61beta compare
MMJJ_RS07210 +0.4 2.0 AmmeMemoRadiSam system protein B compare
MMJJ_RS03600 +0.4 1.5 TrmJ/YjtD family RNA methyltransferase compare
MMJJ_RS00890 +0.4 1.6 coenzyme F420 hydrogenase subunit gamma compare
MMJJ_RS07995 +0.4 1.4 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS06280 +0.4 1.8 hypothetical protein compare
MMJJ_RS04365 +0.4 0.8 helix-turn-helix transcriptional regulator compare
MMJJ_RS08000 +0.4 2.1 HesA/MoeB/ThiF family protein compare
MMJJ_RS05335 +0.4 0.9 heavy metal-binding domain-containing protein compare
MMJJ_RS02230 +0.4 2.0 hypothetical protein compare
MMJJ_RS03075 +0.4 1.8 sodium-dependent transporter compare
MMJJ_RS02170 +0.4 1.3 2-thiouracil desulfurase family protein compare
MMJJ_RS04850 +0.4 1.0 energy-coupling factor transporter transmembrane protein EcfT compare
MMJJ_RS07810 +0.4 1.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMJJ_RS07220 +0.4 1.7 coenzyme F420 hydrogenase subunit beta compare
MMJJ_RS04070 +0.4 2.6 DUF2341 domain-containing protein compare
MMJJ_RS02920 +0.4 0.3 30S ribosomal protein S27ae compare
MMJJ_RS05585 +0.4 1.8 hypothetical protein compare
MMJJ_RS06480 +0.4 1.1 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Novobiocin sodium salt in Methanococcus maripaludis JJ

For stress Novobiocin sodium salt across organisms