Experiment set8S532 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Rifampicin 0.25 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS00060 -4.0 -12.5 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS00055 -3.9 -7.4 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS00065 -3.8 -7.6 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS00050 -3.8 -7.2 AAA family ATPase compare
MMJJ_RS08130 -3.7 -0.7 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS00035 -3.6 -14.7 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS04485 -3.5 -4.2 riboflavin synthase compare
MMJJ_RS00935 -3.5 -11.5 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS04595 -3.5 -2.8 hypothetical protein compare
MMJJ_RS00080 -3.5 -10.8 DUF166 domain-containing protein compare
MMJJ_RS08810 -3.4 -0.6 DUF4040 domain-containing protein compare
MMJJ_RS09095 -3.3 -4.5 MMPL family transporter compare
MMJJ_RS05360 -3.3 -3.9 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS05195 -3.3 -3.4 hypothetical protein compare
MMJJ_RS07955 -3.3 -7.8 ThiF family adenylyltransferase compare
MMJJ_RS00040 -3.2 -6.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS09100 -3.1 -5.6 COG1361 S-layer family protein compare
MMJJ_RS02040 -3.1 -1.0 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS00045 -3.1 -10.0 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS03920 -3.1 -11.0 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS04760 -3.1 -12.7 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS07975 -3.1 -6.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS04755 -3.1 -8.4 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS00075 -3.1 -6.2 AAA family ATPase compare
MMJJ_RS04750 -3.0 -6.7 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS00285 -2.9 -10.6 UPF0254 family protein compare
MMJJ_RS03360 -2.9 -0.8 hypothetical protein compare
MMJJ_RS06915 -2.9 -7.8 helix-turn-helix domain-containing protein compare
MMJJ_RS04475 -2.8 -1.6 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS08575 -2.8 -1.8 hypothetical protein compare
MMJJ_RS05770 -2.8 -1.2 flagellar protein D compare
MMJJ_RS03115 -2.8 -2.8 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS04875 -2.8 -0.7 tRNA-Lys compare
MMJJ_RS01880 -2.7 -1.3 RlmE family RNA methyltransferase compare
MMJJ_RS07360 -2.7 -0.9 TIGR00269 family protein compare
MMJJ_RS01405 -2.7 -0.7 proline--tRNA ligase compare
MMJJ_RS05535 -2.7 -6.2 hypothetical protein compare
MMJJ_RS09055 -2.7 -5.7 NFACT family protein compare
MMJJ_RS08320 -2.7 -1.1 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS07960 -2.7 -1.6 quinolinate synthase NadA compare
MMJJ_RS03160 -2.6 -10.5 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS00450 -2.6 -1.0 DUF126 domain-containing protein compare
MMJJ_RS00525 -2.6 -1.4 Dabb family protein compare
MMJJ_RS09175 -2.6 -0.7 anthranilate synthase component I compare
MMJJ_RS03490 -2.6 -1.0 ribonuclease VapC compare
MMJJ_RS00580 -2.6 -0.8 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS01925 -2.5 -5.6 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMJJ_RS03765 -2.5 -3.4 hypothetical protein compare
MMJJ_RS04525 -2.5 -2.8 hypothetical protein compare
MMJJ_RS03170 -2.5 -5.1 DUF5612 domain-containing protein compare
MMJJ_RS03270 -2.5 -0.9 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS07585 -2.4 -5.1 DHH family phosphoesterase compare
MMJJ_RS05170 -2.4 -7.7 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS00220 -2.4 -4.0 UPF0058 family protein compare
MMJJ_RS03230 -2.3 -1.4 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS00570 -2.3 -0.7 ribonuclease P compare
MMJJ_RS06835 -2.3 -7.7 4Fe-4S binding protein compare
MMJJ_RS07470 -2.3 -0.9 50S ribosome-binding GTPase compare
MMJJ_RS05190 -2.3 -4.4 gamma carbonic anhydrase family protein compare
MMJJ_RS05575 -2.3 -1.4 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS08500 -2.3 -4.2 L-sulfolactate dehydrogenase compare
MMJJ_RS04180 -2.3 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS00645 -2.3 -7.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMJJ_RS06260 -2.2 -4.5 6-carboxyhexanoate--CoA ligase compare
MMJJ_RS03655 -2.2 -3.0 replication factor C large subunit compare
MMJJ_RS09085 -2.2 -8.6 minichromosome maintenance protein MCM compare
MMJJ_RS03930 -2.2 -7.8 hypothetical protein compare
MMJJ_RS00355 -2.2 -1.1 ribonuclease P protein component 4 compare
MMJJ_RS01690 -2.2 -1.2 methanogenesis marker 12 protein compare
MMJJ_RS02200 -2.2 -2.6 chorismate pyruvate-lyase family protein compare
MMJJ_RS08785 -2.2 -5.3 D-sedoheptulose 7-phosphate isomerase compare
MMJJ_RS06660 -2.1 -5.6 DUF1188 domain-containing protein compare
MMJJ_RS06725 -2.1 -5.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS08080 -2.1 -5.2 TIGR00300 family protein compare
MMJJ_RS05065 -2.1 -2.0 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS08340 -2.1 -1.4 archaeoflavoprotein AfpA compare
MMJJ_RS09375 -2.1 -0.7 hypothetical protein compare
MMJJ_RS08020 -2.1 -6.4 nucleotidyltransferase domain-containing protein compare
MMJJ_RS05765 -2.1 -0.5 flagellar protein E compare
MMJJ_RS04970 -2.1 -0.8 DUF655 domain-containing protein compare
MMJJ_RS07670 -2.1 -9.1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS00210 -2.0 -0.8 DUF530 family protein compare
MMJJ_RS06940 -2.0 -6.3 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS04700 -2.0 -1.4 deoxyhypusine synthase compare
MMJJ_RS07950 -2.0 -1.0 4Fe-4S binding protein compare
MMJJ_RS03245 -2.0 -0.5 UMP kinase compare
MMJJ_RS06910 -2.0 -0.9 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS07415 -2.0 -0.9 polyprenyl diphosphate synthase compare
MMJJ_RS08380 -2.0 -1.7 hypothetical protein compare
MMJJ_RS06665 -2.0 -3.1 DUF3236 domain-containing protein compare
MMJJ_RS08715 -2.0 -6.3 NAD-dependent epimerase/dehydratase family protein compare
MMJJ_RS07410 -2.0 -1.2 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS07590 -2.0 -7.1 flap endonuclease-1 compare
MMJJ_RS00475 -2.0 -0.7 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS08625 -2.0 -1.9 magnesium/cobalt transporter CorA compare
MMJJ_RS04655 -2.0 -3.2 FAD-dependent oxidoreductase compare
MMJJ_RS07030 -1.9 -11.5 hypothetical protein compare
MMJJ_RS07245 -1.9 -1.3 amidohydrolase family protein compare
MMJJ_RS08585 -1.9 -5.1 M42 family metallopeptidase compare
MMJJ_RS02855 -1.9 -5.1 DEAD/DEAH box helicase compare
MMJJ_RS01070 -1.9 -1.3 PadR family transcriptional regulator compare
MMJJ_RS01810 -1.9 -0.9 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS08765 -1.9 -9.9 glycosyltransferase family 9 protein compare
MMJJ_RS06375 -1.9 -1.7 UbiX family flavin prenyltransferase compare
MMJJ_RS08775 -1.9 -8.0 PfkB family carbohydrate kinase compare
MMJJ_RS08430 -1.9 -4.1 small nuclear ribonucleoprotein compare
MMJJ_RS07035 -1.9 -0.8 glycosyl transferase compare
MMJJ_RS08410 -1.8 -2.0 CBS domain-containing protein compare
MMJJ_RS05710 -1.8 -1.3 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS06270 -1.8 -4.0 dethiobiotin synthase compare
MMJJ_RS07000 -1.8 -0.7 TrkH family potassium uptake protein compare
MMJJ_RS07350 -1.8 -1.0 4Fe-4S binding protein compare
MMJJ_RS05155 -1.8 -2.0 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMJJ_RS01865 -1.8 -2.9 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS03195 -1.8 -2.7 hypothetical protein compare
MMJJ_RS01500 -1.8 -3.6 transcriptional regulator compare
MMJJ_RS06935 -1.8 -5.8 GTP-binding protein compare
MMJJ_RS03965 -1.8 -0.6 DNA-directed RNA polymerase subunit L compare
MMJJ_RS03225 -1.8 -0.8 4Fe-4S binding protein compare
MMJJ_RS07005 -1.8 -2.5 transcription factor S compare
MMJJ_RS08535 -1.8 -1.3 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS06635 -1.7 -7.2 4Fe-4S binding protein compare
MMJJ_RS03205 -1.7 -3.8 metallophosphoesterase compare
MMJJ_RS06110 -1.7 -0.8 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS08840 -1.7 -1.6 calcium/sodium antiporter compare
MMJJ_RS04730 -1.7 -1.2 tyrosine decarboxylase MfnA compare
MMJJ_RS06155 -1.7 -2.0 phosphatidylglycerophosphatase A compare
MMJJ_RS06785 -1.7 -4.8 RNA ligase partner protein compare
MMJJ_RS03785 -1.7 -0.8 hypothetical protein compare
MMJJ_RS04200 -1.7 -1.2 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS01960 -1.7 -3.6 glycosyltransferase family 2 protein compare
MMJJ_RS05610 -1.7 -1.2 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS07190 -1.7 -1.6 RtcB family protein compare
MMJJ_RS03110 -1.7 -1.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS05655 -1.7 -2.0 HisA/HisF family protein compare
MMJJ_RS00070 -1.7 -1.5 CooT family nickel-binding protein compare
MMJJ_RS04565 -1.7 -1.1 sirohydrochlorin nickelochelatase compare
MMJJ_RS06750 -1.7 -0.7 homoaconitase large subunit compare
MMJJ_RS06240 -1.7 -0.8 dihydropteroate synthase-like protein compare
MMJJ_RS09130 -1.7 -0.6 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS06805 -1.6 -1.0 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS08335 -1.6 -0.6 ABC transporter ATP-binding protein compare
MMJJ_RS08780 -1.6 -4.4 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase compare
MMJJ_RS04865 -1.6 -7.4 4Fe-4S binding protein compare
MMJJ_RS09035 -1.6 -2.6 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS03140 -1.6 -5.3 tRNA-dihydrouridine synthase compare
MMJJ_RS07665 -1.6 -9.2 formate dehydrogenase subunit alpha compare
MMJJ_RS01360 -1.6 -0.7 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS00480 -1.6 -5.8 flippase compare
MMJJ_RS00560 -1.6 -0.9 homoisocitrate dehydrogenase compare
MMJJ_RS05590 -1.6 -0.8 homoserine dehydrogenase compare
MMJJ_RS00345 -1.6 -4.8 4-hydroxy-tetrahydrodipicolinate reductase compare
MMJJ_RS02205 -1.6 -5.6 hypothetical protein compare
MMJJ_RS06600 -1.6 -1.1 DUF555 domain-containing protein compare
MMJJ_RS00395 -1.6 -2.9 DUF473 domain-containing protein compare
MMJJ_RS06875 -1.6 -0.9 hypothetical protein compare
MMJJ_RS04800 -1.6 -1.8 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS03310 -1.6 -0.9 hypothetical protein compare
MMJJ_RS04340 -1.5 -2.4 hypothetical protein compare
MMJJ_RS03585 -1.5 -0.4 methanogenesis marker 6 protein compare
MMJJ_RS07630 -1.5 -7.1 hypothetical protein compare
MMJJ_RS05810 -1.5 -1.8 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS00215 -1.5 -0.7 CCA tRNA nucleotidyltransferase compare
MMJJ_RS08095 -1.5 -1.0 cobyric acid synthase CobQ compare
MMJJ_RS01350 -1.5 -3.3 sodium:proton antiporter compare
MMJJ_RS01410 -1.5 -3.1 archaeal proteasome endopeptidase complex subunit beta compare
MMJJ_RS06755 -1.5 -6.0 diadenylate cyclase compare
MMJJ_RS07155 -1.5 -3.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS09235 -1.5 -1.8 helix-turn-helix transcriptional regulator compare
MMJJ_RS04790 -1.5 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS08155 -1.5 -0.9 cobalt-precorrin-5B (C(1))-methyltransferase CbiD compare
MMJJ_RS03150 -1.5 -1.4 2-phospho-L-lactate transferase compare
MMJJ_RS04995 -1.5 -2.2 Tfx family DNA-binding protein compare
MMJJ_RS07380 -1.5 -4.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS05720 -1.5 -0.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS06860 -1.5 -1.1 hypothetical protein compare
MMJJ_RS02090 -1.5 -1.9 tyramine--L-glutamate ligase compare
MMJJ_RS05380 -1.5 -0.5 hypothetical protein compare
MMJJ_RS05165 -1.5 -3.6 class I SAM-dependent methyltransferase compare
MMJJ_RS06885 -1.4 -0.8 EhaF family protein compare
MMJJ_RS03200 -1.4 -0.6 uroporphyrinogen-III synthase compare
MMJJ_RS04150 -1.4 -1.0 DUF5379 domain-containing protein compare
MMJJ_RS00385 -1.4 -6.3 TIGR00454 family protein compare
MMJJ_RS04415 -1.4 -1.2 hypothetical protein compare
MMJJ_RS09265 -1.4 -1.4 hypothetical protein compare
MMJJ_RS00125 -1.4 -0.7 KEOPS complex subunit Cgi121 compare
MMJJ_RS07935 -1.4 -0.6 protein fwdD compare
MMJJ_RS03295 -1.4 -4.0 PHP domain-containing protein compare
MMJJ_RS01830 -1.4 -1.3 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS08725 -1.4 -6.0 flippase compare
MMJJ_RS04685 -1.4 -2.1 carbamoyltransferase HypF compare
MMJJ_RS07705 -1.4 -0.8 GTP-binding protein EngB compare
MMJJ_RS00600 -1.4 -0.9 hydroxymethylbilane synthase compare
MMJJ_RS06225 -1.4 -0.7 adenosylmethionine decarboxylase compare
MMJJ_RS07265 -1.3 -5.0 tRNA (adenine-N1)-methyltransferase compare
MMJJ_RS07160 -1.3 -7.0 M20 family metallo-hydrolase compare
MMJJ_RS03880 -1.3 -6.1 TraB/GumN family protein compare
MMJJ_RS00270 -1.3 -0.7 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS04360 -1.3 -3.4 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS06745 -1.3 -4.9 energy-coupling factor ABC transporter permease compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in stress experiments

For stress Rifampicin across organisms