Experiment set8S531 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete deta nonoate 0.025 mM

200 most detrimental genes:

  gene name fitness t score description  
MMJJ_RS07875 +2.2 3.3 FAD-dependent oxidoreductase compare
MMJJ_RS04005 +2.2 11.4 acetate--CoA ligase family protein compare
MMJJ_RS03725 +2.1 4.0 sulfurtransferase TusA family protein compare
MMJJ_RS06480 +2.0 10.3 hypothetical protein compare
MMJJ_RS07490 +2.0 3.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMJJ_RS07015 +1.9 1.9 PFL family protein compare
MMJJ_RS06575 +1.7 2.2 prephenate dehydrogenase compare
MMJJ_RS04415 +1.6 5.2 hypothetical protein compare
MMJJ_RS06675 +1.5 7.0 TIGR01212 family radical SAM protein compare
MMJJ_RS06650 +1.5 8.2 cell division protein FtsZ compare
MMJJ_RS07175 +1.4 9.1 DEAD/DEAH box helicase compare
MMJJ_RS01210 +1.3 3.0 hypothetical protein compare
MMJJ_RS04620 +1.3 2.2 homocitrate synthase family protein compare
MMJJ_RS07500 +1.2 5.9 hypothetical protein compare
MMJJ_RS06535 +1.2 7.7 UPF0104 family protein compare
MMJJ_RS08750 +1.2 7.0 glycosyltransferase compare
MMJJ_RS03070 +1.2 3.0 MetS family NSS transporter small subunit compare
MMJJ_RS05745 +1.2 8.2 type II/IV secretion system ATPase subunit compare
MMJJ_RS03835 +1.1 3.0 DUF504 domain-containing protein compare
MMJJ_RS08760 +1.1 5.9 glycosyltransferase family 9 protein compare
MMJJ_RS06945 +1.1 5.1 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMJJ_RS06210 +1.1 3.8 hypothetical protein compare
MMJJ_RS08730 +1.1 7.6 glycosyltransferase family 4 protein compare
MMJJ_RS08770 +1.1 5.2 HAD family hydrolase compare
MMJJ_RS07440 +1.1 6.3 metallophosphoesterase compare
MMJJ_RS07505 +1.1 0.8 DNA-directed RNA polymerase subunit K compare
MMJJ_RS07455 +1.1 3.3 coenzyme F420-reducing hydrogenase, FrhD protein compare
MMJJ_RS06800 +1.1 3.5 prefoldin subunit alpha compare
MMJJ_RS08040 +1.1 5.6 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS05685 +1.0 4.2 class III signal peptide-containing protein compare
MMJJ_RS07405 +1.0 2.0 histone family protein compare
MMJJ_RS03250 +1.0 0.9 DUF2116 family Zn-ribbon domain-containing protein compare
MMJJ_RS05400 +1.0 2.2 CoA-binding protein compare
MMJJ_RS05660 +1.0 4.1 sulfopyruvate decarboxylase subunit beta compare
MMJJ_RS09380 +1.0 1.5 hypothetical protein compare
MMJJ_RS08630 +0.9 3.4 signal recognition particle subunit SRP19/SEC65 family protein compare
MMJJ_RS06975 +0.9 2.3 protein translocase SEC61 complex subunit gamma compare
MMJJ_RS06950 +0.9 4.5 4-demethylwyosine synthase TYW1 compare
MMJJ_RS07795 +0.9 3.4 cupin domain-containing protein compare
MMJJ_RS00440 +0.9 4.1 selenide, water dikinase SelD compare
MMJJ_RS08125 +0.9 4.7 DNA double-strand break repair nuclease NurA compare
MMJJ_RS09390 +0.9 1.5 hypothetical protein compare
MMJJ_RS09120 +0.8 1.1 aspartate kinase compare
MMJJ_RS07850 +0.8 5.8 ATP-binding protein compare
MMJJ_RS07390 +0.8 4.5 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMJJ_RS07225 +0.8 3.8 coenzyme F420 hydrogenase subunit gamma compare
MMJJ_RS08455 +0.8 1.7 tetratricopeptide repeat protein compare
MMJJ_RS01300 +0.8 3.7 MarR family transcriptional regulator compare
MMJJ_RS07435 +0.8 5.5 SMC family ATPase compare
MMJJ_RS07810 +0.8 3.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMJJ_RS01855 +0.8 4.5 MBL fold metallo-hydrolase compare
MMJJ_RS05760 +0.8 5.1 flagellar protein F compare
MMJJ_RS07620 +0.8 3.9 class I SAM-dependent rRNA methyltransferase compare
MMJJ_RS07775 +0.8 3.1 fluoride efflux transporter CrcB compare
MMJJ_RS05755 +0.8 4.4 flagellar protein G compare
MMJJ_RS08310 +0.8 2.8 ZIP family metal transporter compare
MMJJ_RS04105 +0.8 5.3 prepilin peptidase compare
MMJJ_RS05740 +0.7 4.7 archaellar assembly protein FlaJ compare
MMJJ_RS03605 +0.7 1.4 TIGR00297 family protein compare
MMJJ_RS01125 +0.7 1.8 hypothetical protein compare
MMJJ_RS06470 +0.7 3.5 tripartite tricarboxylate transporter permease compare
MMJJ_RS05335 +0.7 1.7 heavy metal-binding domain-containing protein compare
MMJJ_RS07740 +0.7 3.3 DUF2334 domain-containing protein compare
MMJJ_RS00415 +0.7 2.3 DedA family protein compare
MMJJ_RS05750 +0.7 3.6 flagellar accessory protein FlaH compare
MMJJ_RS09230 +0.7 1.6 hypothetical protein compare
MMJJ_RS06770 +0.7 4.0 hypothetical protein compare
MMJJ_RS07025 +0.7 2.2 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMJJ_RS01590 +0.7 0.8 adenine phosphoribosyltransferase compare
MMJJ_RS05250 +0.7 2.6 HDIG domain-containing protein compare
MMJJ_RS00900 +0.6 2.0 PC4/YdbC family ssDNA-binding protein compare
MMJJ_RS09130 +0.6 0.6 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS06205 +0.6 3.1 EamA family transporter compare
MMJJ_RS08720 +0.6 3.5 UDP-glucose/GDP-mannose dehydrogenase family protein compare
MMJJ_RS07860 +0.6 2.3 hypothetical protein compare
MMJJ_RS04480 +0.6 1.2 hypothetical protein compare
MMJJ_RS05160 +0.6 1.1 RNA-binding protein compare
MMJJ_RS07965 +0.6 1.7 hypothetical protein compare
MMJJ_RS06685 +0.6 4.3 S-layer protein compare
MMJJ_RS05035 +0.6 1.9 4Fe-4S binding protein compare
MMJJ_RS05420 +0.6 0.8 DNA-directed DNA polymerase II small subunit compare
MMJJ_RS01515 +0.6 1.6 DUF2178 domain-containing protein compare
MMJJ_RS03935 +0.6 3.5 NAAT family transporter compare
MMJJ_RS06925 +0.6 0.6 GMP synthase subunit A compare
MMJJ_RS05365 +0.6 2.2 DUF2798 domain-containing protein compare
MMJJ_RS07215 +0.6 3.9 TIGR00341 family protein compare
MMJJ_RS07610 +0.6 2.0 DUF2119 domain-containing protein compare
MMJJ_RS06400 +0.6 1.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMJJ_RS06105 +0.6 2.7 DUF99 family protein compare
MMJJ_RS09205 +0.6 2.0 hypothetical protein compare
MMJJ_RS07805 +0.5 1.9 ferredoxin family protein compare
MMJJ_RS05815 +0.5 1.8 hypothetical protein compare
MMJJ_RS04825 +0.5 3.7 2,3-bisphosphoglycerate-independent phosphoglycerate mutase compare
MMJJ_RS06505 +0.5 1.6 prephenate dehydratase compare
MMJJ_RS07905 +0.5 2.4 DUF89 domain-containing protein compare
MMJJ_RS00630 +0.5 2.5 betaine/proline/choline family ABC transporter ATP-binding protein compare
MMJJ_RS05005 +0.5 2.9 hypothetical protein compare
MMJJ_RS06120 +0.5 2.4 DUF4013 domain-containing protein compare
MMJJ_RS06865 +0.5 0.8 NADH-quinone oxidoreductase subunit H compare
MMJJ_RS05925 +0.5 2.2 DUF2099 family protein compare
MMJJ_RS06125 +0.5 2.9 methanogenesis marker 16 metalloprotein compare
MMJJ_RS06465 +0.5 2.6 hypothetical protein compare
MMJJ_RS02115 +0.5 2.3 class I SAM-dependent methyltransferase family protein compare
MMJJ_RS06755 +0.5 2.5 diadenylate cyclase compare
MMJJ_RS09225 +0.5 1.6 hypothetical protein compare
MMJJ_RS00310 +0.5 2.2 protein-glutamate O-methyltransferase CheR compare
MMJJ_RS09250 +0.5 1.2 hypothetical protein compare
MMJJ_RS07780 +0.5 1.4 DUF190 domain-containing protein compare
MMJJ_RS07480 +0.5 3.2 FAD-dependent oxidoreductase compare
MMJJ_RS04830 +0.5 2.4 zinc dependent phospholipase C family protein compare
MMJJ_RS00885 +0.5 1.0 coenzyme F420-reducing hydrogenase, FrhD protein compare
MMJJ_RS03510 +0.5 2.0 acyl-CoA dehydratase activase compare
MMJJ_RS08905 +0.5 2.8 YcaO-related McrA-glycine thioamidation protein compare
MMJJ_RS07865 +0.5 1.9 zinc ribbon domain-containing protein compare
MMJJ_RS07855 +0.5 2.5 YkgJ family cysteine cluster protein compare
MMJJ_RS05505 +0.5 4.2 hypothetical protein compare
MMJJ_RS02145 +0.5 2.5 class I SAM-dependent methyltransferase compare
MMJJ_RS05605 +0.5 1.9 hypothetical protein compare
MMJJ_RS02185 +0.5 1.7 TIGR00296 family protein compare
MMJJ_RS07270 +0.5 2.3 ribonuclease HII compare
MMJJ_RS06020 +0.5 1.0 hypothetical protein compare
MMJJ_RS08885 +0.5 2.4 cysteine--tRNA ligase compare
MMJJ_RS02890 +0.5 2.5 ATP-binding protein compare
MMJJ_RS00295 +0.5 2.5 response regulator compare
MMJJ_RS08365 +0.5 1.4 DsrE family protein compare
MMJJ_RS05890 +0.5 2.6 molybdate ABC transporter substrate-binding protein compare
MMJJ_RS06275 +0.5 1.3 hypothetical protein compare
MMJJ_RS07800 +0.5 3.1 AMP-binding protein compare
MMJJ_RS00420 +0.5 1.7 CBS domain-containing protein compare
MMJJ_RS06765 +0.5 3.1 hypothetical protein compare
MMJJ_RS07230 +0.5 1.9 coenzyme F420-reducing hydrogenase, FrhD protein compare
MMJJ_RS06055 +0.5 2.3 S-methyl-5-thioribose-1-phosphate isomerase compare
MMJJ_RS06500 +0.5 1.7 class I SAM-dependent methyltransferase compare
MMJJ_RS02850 +0.4 1.8 hypothetical protein compare
MMJJ_RS00350 +0.4 2.6 phage infection protein compare
MMJJ_RS01920 +0.4 2.9 phosphoglycerate mutase compare
MMJJ_RS05885 +0.4 3.2 tungstate ABC transporter substrate-binding protein WtpA compare
MMJJ_RS06450 +0.4 2.4 DUF3343 domain-containing protein compare
MMJJ_RS05510 +0.4 2.2 archaellum operon transcriptional activator EarA family protein compare
MMJJ_RS05495 +0.4 2.0 MinD/ParA family protein compare
MMJJ_RS07235 +0.4 2.7 coenzyme F420 hydrogenase subunit alpha compare
MMJJ_RS06710 +0.4 2.7 TldD/PmbA family protein compare
MMJJ_RS03545 +0.4 2.2 flagella protein F compare
MMJJ_RS07910 +0.4 2.0 CBS domain-containing protein compare
MMJJ_RS06655 +0.4 2.1 transcriptional regulator compare
MMJJ_RS06190 +0.4 2.4 7-cyano-7-deazaguanine synthase compare
MMJJ_RS00300 +0.4 1.7 chemotaxis protein CheC compare
MMJJ_RS06130 +0.4 1.5 hypothetical protein compare
MMJJ_RS03530 +0.4 2.3 phosphate ABC transporter substrate-binding protein compare
MMJJ_RS02880 +0.4 1.9 hypothetical protein compare
MMJJ_RS07255 +0.4 2.9 hypothetical protein compare
MMJJ_RS03720 +0.4 1.8 DsrE family protein compare
MMJJ_RS02665 +0.4 0.6 methyl-accepting chemotaxis protein compare
MMJJ_RS00725 +0.4 2.0 LysE family translocator compare
MMJJ_RS00635 +0.4 2.1 ABC transporter permease subunit compare
MMJJ_RS01090 +0.4 1.1 hypothetical protein compare
MMJJ_RS07210 +0.4 2.2 AmmeMemoRadiSam system protein B compare
MMJJ_RS09325 +0.4 1.7 hypothetical protein compare
MMJJ_RS05690 +0.4 3.3 hypothetical protein compare
MMJJ_RS04345 +0.4 0.7 DUF2080 family transposase-associated protein compare
MMJJ_RS06440 +0.4 1.8 DUF4870 domain-containing protein compare
MMJJ_RS06445 +0.4 2.8 hypothetical protein compare
MMJJ_RS06045 +0.4 1.6 hypothetical protein compare
MMJJ_RS00175 +0.4 1.5 cytochrome c biogenesis CcdA family protein compare
MMJJ_RS00405 +0.4 1.3 flavodoxin family protein compare
MMJJ_RS02060 +0.4 1.9 cupin domain-containing protein compare
MMJJ_RS04515 +0.4 2.3 HD domain-containing protein compare
MMJJ_RS02135 +0.4 1.2 TatD family hydrolase compare
MMJJ_RS01785 +0.4 0.3 50S ribosomal protein L14e compare
MMJJ_RS06720 +0.4 1.9 mechanosensitive ion channel family protein compare
MMJJ_RS00760 +0.4 2.1 hypothetical protein compare
MMJJ_RS01035 +0.4 1.1 hypothetical protein compare
MMJJ_RS08235 +0.4 0.6 UPF0147 family protein compare
MMJJ_RS09360 +0.4 1.6 hypothetical protein compare
MMJJ_RS08580 +0.4 0.8 YkgJ family cysteine cluster protein compare
MMJJ_RS03485 +0.4 2.0 radical SAM protein compare
MMJJ_RS06495 +0.4 0.6 hypothetical protein compare
MMJJ_RS09200 +0.4 2.0 Nre family DNA repair protein compare
MMJJ_RS04525 +0.4 1.0 hypothetical protein compare
MMJJ_RS08870 +0.4 0.3 2-isopropylmalate synthase compare
MMJJ_RS09065 +0.4 1.5 hypothetical protein compare
MMJJ_RS04660 +0.4 1.5 hypoxanthine/guanine phosphoribosyltransferase compare
MMJJ_RS06810 +0.4 2.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha compare
MMJJ_RS00540 +0.3 1.2 hypothetical protein compare
MMJJ_RS06455 +0.3 2.0 YeeE/YedE family protein compare
MMJJ_RS03420 +0.3 1.8 hypothetical protein compare
MMJJ_RS08195 +0.3 1.2 DUF4186 domain-containing protein compare
MMJJ_RS00665 +0.3 2.0 lysine 2,3-aminomutase compare
MMJJ_RS01980 +0.3 1.8 cation:proton antiporter compare
MMJJ_RS04850 +0.3 1.5 energy-coupling factor transporter transmembrane protein EcfT compare
MMJJ_RS00290 +0.3 1.8 CheF family chemotaxis protein compare
MMJJ_RS02120 +0.3 0.7 DJ-1/PfpI family protein compare
MMJJ_RS07960 +0.3 0.5 quinolinate synthase NadA compare
MMJJ_RS04610 +0.3 0.7 ribosome assembly RNA-binding protein YhbY compare
MMJJ_RS00390 +0.3 1.8 proteasome assembly chaperone family protein compare
MMJJ_RS01205 +0.3 1.8 DNA adenine methylase compare
MMJJ_RS09220 +0.3 1.5 cupredoxin family copper-binding protein compare
MMJJ_RS04245 +0.3 1.2 flavoprotein compare
MMJJ_RS04210 +0.3 1.0 DUF434 domain-containing protein compare
MMJJ_RS00960 +0.3 1.4 flavodoxin family protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress deta nonoate in Methanococcus maripaludis JJ

For stress deta nonoate across organisms