Experiment set8S530 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Irgasan 0.0125 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS08130 -4.2 -0.6 translation initiation factor IF-2 subunit gamma compare
MMJJ_RS05135 -3.8 -0.7 50S ribosomal protein L18Ae compare
MMJJ_RS00035 -3.6 -19.7 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS07360 -3.4 -0.8 TIGR00269 family protein compare
MMJJ_RS00060 -3.4 -16.8 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS01100 -3.3 -1.1 helix-turn-helix domain-containing protein compare
MMJJ_RS07955 -3.3 -10.3 ThiF family adenylyltransferase compare
MMJJ_RS04485 -3.3 -6.9 riboflavin synthase compare
MMJJ_RS02040 -3.3 -1.1 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS00080 -3.2 -13.2 DUF166 domain-containing protein compare
MMJJ_RS07975 -3.2 -8.9 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS00040 -3.2 -7.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS08585 -3.1 -8.1 M42 family metallopeptidase compare
MMJJ_RS00050 -3.1 -9.0 AAA family ATPase compare
MMJJ_RS09175 -3.1 -0.6 anthranilate synthase component I compare
MMJJ_RS00935 -3.1 -12.1 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS03810 -3.0 -1.0 AIR synthase-related protein compare
MMJJ_RS00055 -3.0 -8.7 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS02855 -3.0 -7.2 DEAD/DEAH box helicase compare
MMJJ_RS00045 -3.0 -14.1 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS07470 -3.0 -0.8 50S ribosome-binding GTPase compare
MMJJ_RS08500 -3.0 -4.5 L-sulfolactate dehydrogenase compare
MMJJ_RS06915 -3.0 -12.2 helix-turn-helix domain-containing protein compare
MMJJ_RS00075 -3.0 -10.3 AAA family ATPase compare
MMJJ_RS07970 -3.0 -1.2 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS00065 -2.9 -6.7 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS04755 -2.9 -11.9 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS00525 -2.9 -1.4 Dabb family protein compare
MMJJ_RS04760 -2.8 -15.6 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS09375 -2.7 -0.6 hypothetical protein compare
MMJJ_RS01690 -2.7 -1.1 methanogenesis marker 12 protein compare
MMJJ_RS03920 -2.6 -11.8 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS03115 -2.6 -3.2 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS08080 -2.6 -7.2 TIGR00300 family protein compare
MMJJ_RS05535 -2.6 -10.2 hypothetical protein compare
MMJJ_RS07410 -2.6 -1.1 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS07505 -2.6 -0.6 DNA-directed RNA polymerase subunit K compare
MMJJ_RS03270 -2.6 -0.9 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS05190 -2.5 -4.5 gamma carbonic anhydrase family protein compare
MMJJ_RS06875 -2.5 -1.1 hypothetical protein compare
MMJJ_RS07040 -2.5 -0.8 preprotein translocase subunit SecY compare
MMJJ_RS01925 -2.5 -6.8 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMJJ_RS00580 -2.5 -0.8 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS00450 -2.5 -0.9 DUF126 domain-containing protein compare
MMJJ_RS05065 -2.5 -2.3 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS07960 -2.4 -1.7 quinolinate synthase NadA compare
MMJJ_RS07190 -2.4 -1.6 RtcB family protein compare
MMJJ_RS04875 -2.4 -0.7 tRNA-Lys compare
MMJJ_RS00355 -2.4 -1.4 ribonuclease P protein component 4 compare
MMJJ_RS06930 -2.4 -0.8 type II methionyl aminopeptidase compare
MMJJ_RS04750 -2.3 -7.0 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS07950 -2.3 -1.1 4Fe-4S binding protein compare
MMJJ_RS00285 -2.3 -8.8 UPF0254 family protein compare
MMJJ_RS04475 -2.3 -2.0 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS00570 -2.3 -0.7 ribonuclease P compare
MMJJ_RS05575 -2.3 -1.6 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS06110 -2.3 -0.8 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS08625 -2.3 -3.4 magnesium/cobalt transporter CorA compare
MMJJ_RS02200 -2.3 -5.2 chorismate pyruvate-lyase family protein compare
MMJJ_RS00210 -2.2 -0.9 DUF530 family protein compare
MMJJ_RS03240 -2.2 -1.1 histone family protein compare
MMJJ_RS03185 -2.2 -1.1 alanine--tRNA ligase compare
MMJJ_RS06240 -2.2 -0.7 dihydropteroate synthase-like protein compare
MMJJ_RS07370 -2.2 -3.1 tRNA 4-thiouridine(8) synthase ThiI compare
MMJJ_RS06695 -2.2 -1.1 amidohydrolase compare
MMJJ_RS04700 -2.1 -3.2 deoxyhypusine synthase compare
MMJJ_RS02035 -2.1 -4.1 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS04970 -2.1 -0.8 DUF655 domain-containing protein compare
MMJJ_RS04720 -2.1 -1.0 IMP dehydrogenase compare
MMJJ_RS06260 -2.1 -4.0 6-carboxyhexanoate--CoA ligase compare
MMJJ_RS06725 -2.1 -9.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS09295 -2.0 -0.5 hypothetical protein compare
MMJJ_RS08840 -2.0 -2.0 calcium/sodium antiporter compare
MMJJ_RS01880 -2.0 -1.5 RlmE family RNA methyltransferase compare
MMJJ_RS03245 -2.0 -0.5 UMP kinase compare
MMJJ_RS03110 -2.0 -1.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS06665 -2.0 -4.2 DUF3236 domain-containing protein compare
MMJJ_RS02045 -2.0 -0.9 molybdenum cofactor guanylyltransferase compare
MMJJ_RS04790 -2.0 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS04800 -2.0 -2.2 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS06660 -2.0 -5.7 DUF1188 domain-containing protein compare
MMJJ_RS04200 -2.0 -2.3 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS06375 -2.0 -1.8 UbiX family flavin prenyltransferase compare
MMJJ_RS03140 -2.0 -6.0 tRNA-dihydrouridine synthase compare
MMJJ_RS00550 -2.0 -5.8 AIR synthase-related protein compare
MMJJ_RS00215 -2.0 -0.6 CCA tRNA nucleotidyltransferase compare
MMJJ_RS00475 -1.9 -0.7 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase compare
MMJJ_RS05195 -1.9 -3.5 hypothetical protein compare
MMJJ_RS05770 -1.9 -1.2 flagellar protein D compare
MMJJ_RS00430 -1.9 -1.3 ribonuclease Z compare
MMJJ_RS08335 -1.9 -0.7 ABC transporter ATP-binding protein compare
MMJJ_RS08020 -1.9 -5.7 nucleotidyltransferase domain-containing protein compare
MMJJ_RS06635 -1.9 -8.7 4Fe-4S binding protein compare
MMJJ_RS03965 -1.9 -0.7 DNA-directed RNA polymerase subunit L compare
MMJJ_RS06910 -1.9 -1.1 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS06270 -1.9 -5.0 dethiobiotin synthase compare
MMJJ_RS01930 -1.9 -4.5 Pre-mRNA processing ribonucleoprotein compare
MMJJ_RS00125 -1.8 -0.7 KEOPS complex subunit Cgi121 compare
MMJJ_RS09085 -1.8 -8.0 minichromosome maintenance protein MCM compare
MMJJ_RS07425 -1.8 -6.5 MBL fold metallo-hydrolase compare
MMJJ_RS06835 -1.8 -7.6 4Fe-4S binding protein compare
MMJJ_RS05170 -1.8 -6.9 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS04050 -1.8 -0.4 dihydroneopterin aldolase family protein compare
MMJJ_RS00560 -1.8 -1.0 homoisocitrate dehydrogenase compare
MMJJ_RS07160 -1.8 -11.1 M20 family metallo-hydrolase compare
MMJJ_RS08235 -1.8 -2.1 UPF0147 family protein compare
MMJJ_RS03170 -1.8 -5.2 DUF5612 domain-containing protein compare
MMJJ_RS06180 -1.8 -0.7 tryptophan--tRNA ligase compare
MMJJ_RS01830 -1.8 -1.4 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS06390 -1.8 -0.5 NADPH-dependent F420 reductase compare
MMJJ_RS03095 -1.8 -0.8 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS03150 -1.8 -2.2 2-phospho-L-lactate transferase compare
MMJJ_RS08470 -1.8 -1.7 ferredoxin family protein compare
MMJJ_RS03655 -1.8 -2.8 replication factor C large subunit compare
MMJJ_RS06175 -1.8 -0.5 DUF1743 domain-containing protein compare
MMJJ_RS01590 -1.7 -0.9 adenine phosphoribosyltransferase compare
MMJJ_RS06030 -1.7 -2.8 4Fe-4S binding protein compare
MMJJ_RS00270 -1.7 -0.7 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS03125 -1.7 -1.5 GMC oxidoreductase compare
MMJJ_RS00645 -1.7 -6.6 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMJJ_RS07715 -1.7 -1.7 UbiD family decarboxylase compare
MMJJ_RS04180 -1.7 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS04595 -1.7 -2.0 hypothetical protein compare
MMJJ_RS07705 -1.7 -0.9 GTP-binding protein EngB compare
MMJJ_RS00205 -1.7 -2.3 adenosylcobinamide-phosphate synthase CbiB compare
MMJJ_RS07590 -1.7 -5.8 flap endonuclease-1 compare
MMJJ_RS02090 -1.7 -2.2 tyramine--L-glutamate ligase compare
MMJJ_RS05445 -1.7 -0.4 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS06265 -1.7 -8.0 8-amino-7-oxononanoate synthase compare
MMJJ_RS03895 -1.7 -0.8 hydrogenase expression/formation protein HypE compare
MMJJ_RS05655 -1.7 -4.5 HisA/HisF family protein compare
MMJJ_RS08575 -1.7 -1.8 hypothetical protein compare
MMJJ_RS03200 -1.7 -0.7 uroporphyrinogen-III synthase compare
MMJJ_RS03080 -1.7 -4.9 carbohydrate kinase family protein compare
MMJJ_RS03760 -1.7 -0.7 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS08010 -1.7 -4.2 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS01810 -1.6 -0.7 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS03195 -1.6 -2.4 hypothetical protein compare
MMJJ_RS00345 -1.6 -6.0 4-hydroxy-tetrahydrodipicolinate reductase compare
MMJJ_RS08430 -1.6 -2.7 small nuclear ribonucleoprotein compare
MMJJ_RS04655 -1.6 -3.4 FAD-dependent oxidoreductase compare
MMJJ_RS06220 -1.6 -2.5 polyamine aminopropyltransferase compare
MMJJ_RS08810 -1.6 -0.4 DUF4040 domain-containing protein compare
MMJJ_RS01500 -1.6 -4.5 transcriptional regulator compare
MMJJ_RS04965 -1.6 -1.8 RNA polymerase Rpb4 family protein compare
MMJJ_RS05780 -1.6 -1.3 flagellin compare
MMJJ_RS04975 -1.6 -0.5 glycosyltransferase family 4 protein compare
MMJJ_RS04685 -1.6 -4.2 carbamoyltransferase HypF compare
MMJJ_RS05995 -1.6 -0.6 ATP-binding cassette domain-containing protein compare
MMJJ_RS06155 -1.6 -2.3 phosphatidylglycerophosphatase A compare
MMJJ_RS00385 -1.6 -7.4 TIGR00454 family protein compare
MMJJ_RS05415 -1.6 -0.5 hypothetical protein compare
MMJJ_RS05360 -1.6 -3.4 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS08060 -1.6 -4.7 DNA repair and recombination protein RadA compare
MMJJ_RS04525 -1.5 -1.8 hypothetical protein compare
MMJJ_RS07585 -1.5 -5.1 DHH family phosphoesterase compare
MMJJ_RS06600 -1.5 -1.2 DUF555 domain-containing protein compare
MMJJ_RS04375 -1.5 -2.0 hypothetical protein compare
MMJJ_RS03135 -1.5 -2.4 CBS domain-containing protein compare
MMJJ_RS05165 -1.5 -4.9 class I SAM-dependent methyltransferase compare
MMJJ_RS05720 -1.5 -0.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS07980 -1.5 -6.2 biotin synthase BioB compare
MMJJ_RS01405 -1.5 -0.6 proline--tRNA ligase compare
MMJJ_RS00600 -1.5 -1.0 hydroxymethylbilane synthase compare
MMJJ_RS04615 -1.5 -1.6 methanogenesis marker 3 protein compare
MMJJ_RS06860 -1.5 -1.2 hypothetical protein compare
MMJJ_RS06215 -1.5 -1.9 agmatinase compare
MMJJ_RS07245 -1.5 -2.3 amidohydrolase family protein compare
MMJJ_RS01085 -1.4 -2.7 hypothetical protein compare
MMJJ_RS03490 -1.4 -0.9 ribonuclease VapC compare
MMJJ_RS01415 -1.4 -0.5 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS06705 -1.4 -2.1 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS03915 -1.4 -3.8 hypothetical protein compare
MMJJ_RS09265 -1.4 -0.9 hypothetical protein compare
MMJJ_RS08535 -1.4 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS07035 -1.4 -0.7 glycosyl transferase compare
MMJJ_RS07380 -1.4 -4.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS00220 -1.4 -3.0 UPF0058 family protein compare
MMJJ_RS01750 -1.4 -0.4 ferrous iron transport protein A compare
MMJJ_RS03380 -1.4 -1.7 hypothetical protein compare
MMJJ_RS03230 -1.4 -1.8 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS01350 -1.4 -3.2 sodium:proton antiporter compare
MMJJ_RS04980 -1.4 -2.1 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS05380 -1.4 -0.5 hypothetical protein compare
MMJJ_RS01200 -1.4 -0.5 PRC-barrel domain-containing protein compare
MMJJ_RS07720 -1.4 -0.4 UPF0058 family protein compare
MMJJ_RS02205 -1.4 -5.4 hypothetical protein compare
MMJJ_RS05935 -1.3 -0.7 Era-like GTP-binding protein compare
MMJJ_RS07000 -1.3 -0.7 TrkH family potassium uptake protein compare
MMJJ_RS07630 -1.3 -5.5 hypothetical protein compare
MMJJ_RS00070 -1.3 -1.3 CooT family nickel-binding protein compare
MMJJ_RS07155 -1.3 -5.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS03610 -1.3 -2.2 HIT family protein compare
MMJJ_RS03765 -1.3 -2.7 hypothetical protein compare
MMJJ_RS03930 -1.3 -6.3 hypothetical protein compare
MMJJ_RS06715 -1.3 -6.1 lactaldehyde dehydrogenase compare
MMJJ_RS08035 -1.3 -3.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMJJ_RS05375 -1.3 -7.4 radical SAM protein compare
MMJJ_RS03785 -1.3 -0.9 hypothetical protein compare
MMJJ_RS08380 -1.3 -1.7 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in stress experiments

For stress Irgasan across organisms