Experiment set8S520 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Polymyxin B sulfate 0.05 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS08575 -4.4 -1.7 hypothetical protein compare
MMJJ_RS07505 -4.1 -0.6 DNA-directed RNA polymerase subunit K compare
MMJJ_RS00040 -4.0 -8.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS08320 -3.8 -1.3 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
MMJJ_RS00450 -3.7 -1.1 DUF126 domain-containing protein compare
MMJJ_RS00480 -3.7 -12.7 flippase compare
MMJJ_RS00055 -3.6 -10.4 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS02040 -3.5 -1.2 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS00570 -3.4 -0.9 ribonuclease P compare
MMJJ_RS05770 -3.4 -1.6 flagellar protein D compare
MMJJ_RS00430 -3.4 -1.6 ribonuclease Z compare
MMJJ_RS06600 -3.4 -1.1 DUF555 domain-containing protein compare
MMJJ_RS01405 -3.4 -0.7 proline--tRNA ligase compare
MMJJ_RS00060 -3.3 -18.2 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS06665 -3.3 -4.9 DUF3236 domain-containing protein compare
MMJJ_RS07590 -3.3 -13.0 flap endonuclease-1 compare
MMJJ_RS00935 -3.2 -14.5 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS00045 -3.2 -14.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS03230 -3.2 -2.1 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS06915 -3.2 -12.4 helix-turn-helix domain-containing protein compare
MMJJ_RS00050 -3.2 -9.9 AAA family ATPase compare
MMJJ_RS09375 -3.2 -0.8 hypothetical protein compare
MMJJ_RS05065 -3.2 -2.6 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS07715 -3.1 -2.1 UbiD family decarboxylase compare
MMJJ_RS07655 -3.1 -13.6 hypothetical protein compare
MMJJ_RS00035 -3.1 -17.0 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS02200 -3.1 -5.2 chorismate pyruvate-lyase family protein compare
MMJJ_RS04760 -3.1 -17.0 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS09085 -3.1 -11.0 minichromosome maintenance protein MCM compare
MMJJ_RS04970 -3.0 -0.9 DUF655 domain-containing protein compare
MMJJ_RS08625 -3.0 -2.9 magnesium/cobalt transporter CorA compare
MMJJ_RS08830 -3.0 -4.4 hypothetical protein compare
MMJJ_RS08840 -3.0 -1.6 calcium/sodium antiporter compare
MMJJ_RS03115 -3.0 -4.7 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS04750 -3.0 -9.1 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS07360 -3.0 -1.1 TIGR00269 family protein compare
MMJJ_RS05535 -3.0 -11.4 hypothetical protein compare
MMJJ_RS03270 -3.0 -1.2 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS08080 -3.0 -8.4 TIGR00300 family protein compare
MMJJ_RS05280 -2.9 -0.6 hypothetical protein compare
MMJJ_RS05360 -2.9 -5.4 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS01880 -2.9 -1.9 RlmE family RNA methyltransferase compare
MMJJ_RS00065 -2.9 -7.7 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS08430 -2.9 -5.6 small nuclear ribonucleoprotein compare
MMJJ_RS02090 -2.8 -2.2 tyramine--L-glutamate ligase compare
MMJJ_RS04150 -2.8 -1.6 DUF5379 domain-containing protein compare
MMJJ_RS04475 -2.8 -2.5 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS03920 -2.8 -14.7 nickel pincer cofactor biosynthesis protein LarC compare
MMJJ_RS03965 -2.8 -0.7 DNA-directed RNA polymerase subunit L compare
MMJJ_RS04485 -2.8 -5.0 riboflavin synthase compare
MMJJ_RS03785 -2.8 -1.1 hypothetical protein compare
MMJJ_RS03225 -2.8 -1.0 4Fe-4S binding protein compare
MMJJ_RS04575 -2.8 -8.4 DUF116 domain-containing protein compare
MMJJ_RS07960 -2.8 -1.5 quinolinate synthase NadA compare
MMJJ_RS07470 -2.7 -1.1 50S ribosome-binding GTPase compare
MMJJ_RS00075 -2.7 -10.9 AAA family ATPase compare
MMJJ_RS09130 -2.7 -0.8 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS07040 -2.7 -0.8 preprotein translocase subunit SecY compare
MMJJ_RS08490 -2.7 -2.4 rubrerythrin family protein compare
MMJJ_RS06375 -2.7 -2.2 UbiX family flavin prenyltransferase compare
MMJJ_RS05560 -2.7 -4.0 30S ribosomal protein S27e compare
MMJJ_RS04200 -2.7 -1.7 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS01690 -2.7 -2.0 methanogenesis marker 12 protein compare
MMJJ_RS00210 -2.7 -1.2 DUF530 family protein compare
MMJJ_RS01765 -2.7 -8.2 winged helix-turn-helix domain-containing protein compare
MMJJ_RS06940 -2.7 -8.0 metalloregulator ArsR/SmtB family transcription factor compare
MMJJ_RS06835 -2.7 -12.1 4Fe-4S binding protein compare
MMJJ_RS01960 -2.7 -5.0 glycosyltransferase family 2 protein compare
MMJJ_RS06695 -2.7 -1.1 amidohydrolase compare
MMJJ_RS09055 -2.7 -7.2 NFACT family protein compare
MMJJ_RS00080 -2.7 -13.1 DUF166 domain-containing protein compare
MMJJ_RS07585 -2.7 -8.4 DHH family phosphoesterase compare
MMJJ_RS07000 -2.7 -0.8 TrkH family potassium uptake protein compare
MMJJ_RS06725 -2.6 -10.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS07485 -2.6 -6.9 DedA family protein compare
MMJJ_RS05765 -2.6 -0.5 flagellar protein E compare
MMJJ_RS09035 -2.6 -3.9 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS06910 -2.6 -1.3 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS03205 -2.6 -6.5 metallophosphoesterase compare
MMJJ_RS04800 -2.6 -2.8 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS03155 -2.6 -6.2 hypothetical protein compare
MMJJ_RS01530 -2.6 -2.0 YwbE family protein compare
MMJJ_RS04755 -2.6 -9.0 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS05190 -2.6 -6.4 gamma carbonic anhydrase family protein compare
MMJJ_RS00560 -2.6 -1.1 homoisocitrate dehydrogenase compare
MMJJ_RS09175 -2.6 -0.9 anthranilate synthase component I compare
MMJJ_RS01360 -2.6 -0.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS08500 -2.6 -5.1 L-sulfolactate dehydrogenase compare
MMJJ_RS07190 -2.6 -1.9 RtcB family protein compare
MMJJ_RS07245 -2.6 -2.6 amidohydrolase family protein compare
MMJJ_RS04685 -2.6 -4.2 carbamoyltransferase HypF compare
MMJJ_RS06750 -2.6 -0.8 homoaconitase large subunit compare
MMJJ_RS08020 -2.5 -6.3 nucleotidyltransferase domain-containing protein compare
MMJJ_RS08010 -2.5 -6.1 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS04730 -2.5 -1.7 tyrosine decarboxylase MfnA compare
MMJJ_RS00355 -2.5 -1.9 ribonuclease P protein component 4 compare
MMJJ_RS08060 -2.5 -7.4 DNA repair and recombination protein RadA compare
MMJJ_RS06755 -2.5 -10.6 diadenylate cyclase compare
MMJJ_RS07415 -2.5 -1.3 polyprenyl diphosphate synthase compare
MMJJ_RS05590 -2.5 -1.4 homoserine dehydrogenase compare
MMJJ_RS05610 -2.4 -2.3 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMJJ_RS05720 -2.4 -0.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMJJ_RS03200 -2.4 -0.8 uroporphyrinogen-III synthase compare
MMJJ_RS04700 -2.4 -4.4 deoxyhypusine synthase compare
MMJJ_RS07950 -2.4 -1.3 4Fe-4S binding protein compare
MMJJ_RS06110 -2.4 -1.2 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC compare
MMJJ_RS06255 -2.4 -2.8 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 compare
MMJJ_RS03310 -2.4 -1.5 hypothetical protein compare
MMJJ_RS04505 -2.4 -4.2 CDC48 family AAA ATPase compare
MMJJ_RS03930 -2.4 -10.1 hypothetical protein compare
MMJJ_RS04595 -2.4 -3.2 hypothetical protein compare
MMJJ_RS02045 -2.4 -1.2 molybdenum cofactor guanylyltransferase compare
MMJJ_RS08325 -2.3 -1.8 glycosyltransferase family 2 protein compare
MMJJ_RS03620 -2.3 -1.4 DUF2097 domain-containing protein compare
MMJJ_RS07975 -2.3 -7.0 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS00550 -2.3 -7.5 AIR synthase-related protein compare
MMJJ_RS06340 -2.3 -1.9 coenzyme-B sulfoethylthiotransferase subunit alpha compare
MMJJ_RS01825 -2.3 -4.5 DNA repair and recombination protein RadB compare
MMJJ_RS06380 -2.3 -1.1 signal recognition particle protein Srp54 compare
MMJJ_RS03110 -2.3 -2.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS00580 -2.3 -1.0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS06855 -2.3 -0.6 DUF2104 domain-containing protein compare
MMJJ_RS01865 -2.3 -4.1 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS00285 -2.3 -9.5 UPF0254 family protein compare
MMJJ_RS07955 -2.3 -7.4 ThiF family adenylyltransferase compare
MMJJ_RS00270 -2.3 -1.0 adenosylcobinamide-GDP ribazoletransferase compare
MMJJ_RS04050 -2.3 -0.6 dihydroneopterin aldolase family protein compare
MMJJ_RS07705 -2.3 -1.0 GTP-binding protein EngB compare
MMJJ_RS04980 -2.3 -2.3 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS08825 -2.3 -3.9 hypothetical protein compare
MMJJ_RS07945 -2.2 -0.9 4Fe-4S binding protein compare
MMJJ_RS03190 -2.2 -0.9 phosphopyruvate hydratase compare
MMJJ_RS08620 -2.2 -2.7 DUF373 family protein compare
MMJJ_RS09295 -2.2 -0.6 hypothetical protein compare
MMJJ_RS06860 -2.2 -1.7 hypothetical protein compare
MMJJ_RS05780 -2.2 -1.7 flagellin compare
MMJJ_RS07670 -2.2 -12.5 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS07665 -2.2 -15.5 formate dehydrogenase subunit alpha compare
MMJJ_RS05170 -2.2 -7.7 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS07935 -2.2 -0.9 protein fwdD compare
MMJJ_RS06705 -2.2 -2.6 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS07155 -2.2 -6.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS01810 -2.1 -1.1 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS04790 -2.1 -1.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS07005 -2.1 -2.7 transcription factor S compare
MMJJ_RS00345 -2.1 -6.3 4-hydroxy-tetrahydrodipicolinate reductase compare
MMJJ_RS08005 -2.1 -12.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS03875 -2.1 -1.3 CBS domain-containing protein compare
MMJJ_RS07280 -2.1 -5.7 phosphomannomutase/phosphoglucomutase compare
MMJJ_RS06220 -2.0 -3.3 polyamine aminopropyltransferase compare
MMJJ_RS04875 -2.0 -0.8 tRNA-Lys compare
MMJJ_RS06180 -2.0 -1.2 tryptophan--tRNA ligase compare
MMJJ_RS03765 -2.0 -4.7 hypothetical protein compare
MMJJ_RS03150 -2.0 -2.8 2-phospho-L-lactate transferase compare
MMJJ_RS05655 -2.0 -5.9 HisA/HisF family protein compare
MMJJ_RS05415 -2.0 -0.7 hypothetical protein compare
MMJJ_RS05995 -2.0 -0.9 ATP-binding cassette domain-containing protein compare
MMJJ_RS03060 -2.0 -0.8 methanogenesis marker 7 protein compare
MMJJ_RS01200 -2.0 -0.9 PRC-barrel domain-containing protein compare
MMJJ_RS08850 -2.0 -1.0 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
MMJJ_RS06905 -2.0 -1.0 hypothetical protein compare
MMJJ_RS03760 -2.0 -1.2 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS00125 -2.0 -1.2 KEOPS complex subunit Cgi121 compare
MMJJ_RS05650 -2.0 -0.8 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS07380 -1.9 -6.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS08535 -1.9 -2.1 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS02855 -1.9 -4.8 DEAD/DEAH box helicase compare
MMJJ_RS00645 -1.9 -8.6 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMJJ_RS03810 -1.9 -1.9 AIR synthase-related protein compare
MMJJ_RS06155 -1.9 -2.9 phosphatidylglycerophosphatase A compare
MMJJ_RS06200 -1.9 -1.2 phosphoglycerate dehydrogenase compare
MMJJ_RS08710 -1.9 -7.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMJJ_RS00070 -1.9 -1.9 CooT family nickel-binding protein compare
MMJJ_RS03160 -1.9 -7.7 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS03095 -1.9 -1.2 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS05375 -1.9 -10.3 radical SAM protein compare
MMJJ_RS06480 -1.9 -7.4 hypothetical protein compare
MMJJ_RS03670 -1.9 -2.0 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS06660 -1.9 -5.5 DUF1188 domain-containing protein compare
MMJJ_RS05380 -1.9 -0.6 hypothetical protein compare
MMJJ_RS08725 -1.9 -10.3 flippase compare
MMJJ_RS05710 -1.9 -2.8 single-stranded-DNA-specific exonuclease RecJ compare
MMJJ_RS06260 -1.8 -5.1 6-carboxyhexanoate--CoA ligase compare
MMJJ_RS05725 -1.8 -7.2 UPF0179 family protein compare
MMJJ_RS05785 -1.8 -8.1 flagellin compare
MMJJ_RS08795 -1.8 -0.7 phosphoglucosamine mutase compare
MMJJ_RS03005 -1.8 -1.2 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS06390 -1.8 -0.7 NADPH-dependent F420 reductase compare
MMJJ_RS05070 -1.8 -0.6 DNA primase catalytic subunit PriS compare
MMJJ_RS08855 -1.8 -2.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS04110 -1.8 -5.2 hypothetical protein compare
MMJJ_RS01475 -1.8 -0.6 signal recognition particle-docking protein FtsY compare
MMJJ_RS07630 -1.8 -7.3 hypothetical protein compare
MMJJ_RS08715 -1.8 -5.8 NAD-dependent epimerase/dehydratase family protein compare
MMJJ_RS00370 -1.8 -0.5 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS08585 -1.8 -4.7 M42 family metallopeptidase compare
MMJJ_RS01870 -1.8 -0.8 methanogenesis marker 15 protein compare
MMJJ_RS04520 -1.8 -2.2 coenzyme F430 synthase compare
MMJJ_RS01750 -1.8 -0.9 ferrous iron transport protein A compare
MMJJ_RS00425 -1.8 -2.3 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Polymyxin B sulfate in Methanococcus maripaludis JJ

For stress Polymyxin B sulfate across organisms