Experiment set8S507 for Methanococcus maripaludis JJ

Compare to:

McCas_formate_complete Spiramycin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMJJ_RS08855 -4.6 -3.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMJJ_RS00450 -4.0 -1.6 DUF126 domain-containing protein compare
MMJJ_RS03270 -3.9 -1.5 ribosome biogenesis/translation initiation ATPase RLI compare
MMJJ_RS07970 -3.9 -1.9 O-phospho-L-seryl-tRNA:Cys-tRNA synthase compare
MMJJ_RS05065 -3.8 -3.5 (4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase compare
MMJJ_RS03230 -3.8 -2.4 NAD(P)/FAD-dependent oxidoreductase compare
MMJJ_RS07470 -3.7 -1.4 50S ribosome-binding GTPase compare
MMJJ_RS05560 -3.7 -5.4 30S ribosomal protein S27e compare
MMJJ_RS07715 -3.7 -2.6 UbiD family decarboxylase compare
MMJJ_RS05590 -3.6 -1.4 homoserine dehydrogenase compare
MMJJ_RS04485 -3.6 -7.9 riboflavin synthase compare
MMJJ_RS04720 -3.5 -1.3 IMP dehydrogenase compare
MMJJ_RS07950 -3.4 -1.8 4Fe-4S binding protein compare
MMJJ_RS00210 -3.4 -1.5 DUF530 family protein compare
MMJJ_RS09175 -3.4 -0.9 anthranilate synthase component I compare
MMJJ_RS01405 -3.3 -0.9 proline--tRNA ligase compare
MMJJ_RS01865 -3.3 -5.0 peptidyl-tRNA hydrolase Pth2 compare
MMJJ_RS08135 -3.3 -5.3 30S ribosomal protein S6e compare
MMJJ_RS07360 -3.3 -1.5 TIGR00269 family protein compare
MMJJ_RS07410 -3.3 -2.1 methanogenesis marker protein Mmp4/MtxX compare
MMJJ_RS06875 -3.2 -1.8 hypothetical protein compare
MMJJ_RS07505 -3.2 -0.9 DNA-directed RNA polymerase subunit K compare
MMJJ_RS06910 -3.2 -2.1 energy-converting NiFe hydrogenase A subunit EhaA compare
MMJJ_RS09130 -3.2 -1.2 NFYB/HAP3 family transcription factor subunit compare
MMJJ_RS00050 -3.1 -9.6 AAA family ATPase compare
MMJJ_RS07000 -3.1 -1.2 TrkH family potassium uptake protein compare
MMJJ_RS01350 -3.1 -6.7 sodium:proton antiporter compare
MMJJ_RS03225 -3.1 -1.5 4Fe-4S binding protein compare
MMJJ_RS08840 -3.1 -3.6 calcium/sodium antiporter compare
MMJJ_RS00065 -3.0 -10.4 4Fe-4S dicluster domain-containing protein compare
MMJJ_RS05225 -3.0 -0.8 Gar1/Naf1 family protein compare
MMJJ_RS05380 -3.0 -0.8 hypothetical protein compare
MMJJ_RS03055 -2.9 -2.2 hypothetical protein compare
MMJJ_RS00785 -2.9 -2.7 hypothetical protein compare
MMJJ_RS05575 -2.9 -2.9 2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase compare
MMJJ_RS04150 -2.9 -2.5 DUF5379 domain-containing protein compare
MMJJ_RS08625 -2.9 -5.4 magnesium/cobalt transporter CorA compare
MMJJ_RS00215 -2.8 -1.4 CCA tRNA nucleotidyltransferase compare
MMJJ_RS04145 -2.8 -8.5 glutamate-1-semialdehyde 2,1-aminomutase compare
MMJJ_RS08660 -2.8 -2.3 acetylornithine transaminase compare
MMJJ_RS08535 -2.8 -3.0 NOL1/NOP2/sun family putative RNA methylase compare
MMJJ_RS06885 -2.8 -1.7 EhaF family protein compare
MMJJ_RS03200 -2.8 -1.2 uroporphyrinogen-III synthase compare
MMJJ_RS06725 -2.8 -10.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMJJ_RS06860 -2.7 -2.4 hypothetical protein compare
MMJJ_RS06695 -2.7 -2.0 amidohydrolase compare
MMJJ_RS06225 -2.7 -1.6 adenosylmethionine decarboxylase compare
MMJJ_RS00125 -2.7 -1.4 KEOPS complex subunit Cgi121 compare
MMJJ_RS06855 -2.7 -0.9 DUF2104 domain-containing protein compare
MMJJ_RS06905 -2.7 -1.0 hypothetical protein compare
MMJJ_RS07190 -2.7 -3.5 RtcB family protein compare
MMJJ_RS00045 -2.7 -12.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMJJ_RS02045 -2.7 -2.0 molybdenum cofactor guanylyltransferase compare
MMJJ_RS02090 -2.7 -4.0 tyramine--L-glutamate ligase compare
MMJJ_RS00040 -2.7 -8.7 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMJJ_RS07945 -2.7 -1.4 4Fe-4S binding protein compare
MMJJ_RS04050 -2.7 -0.9 dihydroneopterin aldolase family protein compare
MMJJ_RS07245 -2.6 -3.5 amidohydrolase family protein compare
MMJJ_RS00035 -2.6 -16.3 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMJJ_RS03190 -2.6 -1.5 phosphopyruvate hydratase compare
MMJJ_RS09375 -2.6 -1.2 hypothetical protein compare
MMJJ_RS00060 -2.6 -14.4 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMJJ_RS00580 -2.6 -1.2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG compare
MMJJ_RS08330 -2.6 -1.5 SufD family Fe-S cluster assembly protein compare
MMJJ_RS08080 -2.6 -9.0 TIGR00300 family protein compare
MMJJ_RS04475 -2.6 -3.6 3,4-dihydroxy-2-butanone-4-phosphate synthase compare
MMJJ_RS06915 -2.6 -13.0 helix-turn-helix domain-containing protein compare
MMJJ_RS05535 -2.6 -10.9 hypothetical protein compare
MMJJ_RS00570 -2.5 -1.3 ribonuclease P compare
MMJJ_RS03580 -2.5 -1.4 TIGR00303 family protein compare
MMJJ_RS03005 -2.5 -1.6 Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit compare
MMJJ_RS06240 -2.5 -1.7 dihydropteroate synthase-like protein compare
MMJJ_RS06155 -2.5 -3.8 phosphatidylglycerophosphatase A compare
MMJJ_RS07430 -2.5 -3.2 ribonuclease VapC compare
MMJJ_RS04730 -2.5 -2.4 tyrosine decarboxylase MfnA compare
MMJJ_RS08020 -2.5 -7.4 nucleotidyltransferase domain-containing protein compare
MMJJ_RS00055 -2.4 -9.0 CO dehydrogenase/acetyl-CoA synthase subunit delta compare
MMJJ_RS05835 -2.4 -13.9 bis-aminopropyl spermidine synthase family protein conserved
MMJJ_RS05360 -2.4 -6.9 nickel-responsive transcriptional regulator NikR compare
MMJJ_RS01360 -2.4 -1.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMJJ_RS03110 -2.4 -3.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase compare
MMJJ_RS08430 -2.4 -5.0 small nuclear ribonucleoprotein compare
MMJJ_RS07350 -2.4 -2.5 4Fe-4S binding protein compare
MMJJ_RS03620 -2.4 -3.5 DUF2097 domain-containing protein compare
MMJJ_RS01870 -2.4 -1.0 methanogenesis marker 15 protein compare
MMJJ_RS00075 -2.4 -9.2 AAA family ATPase compare
MMJJ_RS03295 -2.4 -10.5 PHP domain-containing protein compare
MMJJ_RS07380 -2.4 -6.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMJJ_RS04200 -2.3 -4.1 triphosphoribosyl-dephospho-CoA synthase compare
MMJJ_RS09035 -2.3 -4.2 OB-fold nucleic acid binding domain-containing protein compare
MMJJ_RS03670 -2.3 -3.1 precorrin-2 C(20)-methyltransferase compare
MMJJ_RS06180 -2.3 -1.8 tryptophan--tRNA ligase compare
MMJJ_RS06755 -2.3 -11.8 diadenylate cyclase compare
MMJJ_RS05650 -2.3 -1.3 formylmethanofuran dehydrogenase subunit B compare
MMJJ_RS06220 -2.3 -4.5 polyamine aminopropyltransferase compare
MMJJ_RS04520 -2.3 -3.4 coenzyme F430 synthase compare
MMJJ_RS04800 -2.3 -4.5 2-phospho-L-lactate guanylyltransferase compare
MMJJ_RS08795 -2.3 -1.2 phosphoglucosamine mutase compare
MMJJ_RS07375 -2.3 -8.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMJJ_RS07725 -2.3 -5.1 DNA primase DnaG compare
MMJJ_RS05995 -2.3 -1.4 ATP-binding cassette domain-containing protein compare
MMJJ_RS03765 -2.3 -5.1 hypothetical protein compare
MMJJ_RS01810 -2.3 -1.4 methyl coenzyme M reductase system, component A2 compare
MMJJ_RS04790 -2.3 -2.5 biotin--[acetyl-CoA-carboxylase] ligase compare
MMJJ_RS06600 -2.3 -1.7 DUF555 domain-containing protein compare
MMJJ_RS09295 -2.2 -0.8 hypothetical protein compare
MMJJ_RS07705 -2.2 -2.1 GTP-binding protein EngB compare
MMJJ_RS06390 -2.2 -1.2 NADPH-dependent F420 reductase compare
MMJJ_RS01755 -2.2 -1.1 ferrous iron transport protein B compare
MMJJ_RS03125 -2.2 -2.9 GMC oxidoreductase compare
MMJJ_RS07720 -2.2 -0.8 UPF0058 family protein compare
MMJJ_RS03170 -2.2 -6.1 DUF5612 domain-containing protein compare
MMJJ_RS00370 -2.2 -0.8 asparagine synthase (glutamine-hydrolyzing) compare
MMJJ_RS04595 -2.2 -3.8 hypothetical protein compare
MMJJ_RS01415 -2.2 -1.4 beta-CASP ribonuclease aCPSF1 compare
MMJJ_RS04685 -2.2 -6.1 carbamoyltransferase HypF compare
MMJJ_RS00080 -2.1 -9.9 DUF166 domain-containing protein compare
MMJJ_RS00275 -2.1 -0.9 coenzyme F420-0:L-glutamate ligase compare
MMJJ_RS01935 -2.1 -1.3 O-phosphoseryl-tRNA(Sec) selenium transferase compare
MMJJ_RS03810 -2.1 -2.4 AIR synthase-related protein compare
MMJJ_RS08005 -2.1 -12.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMJJ_RS08095 -2.1 -3.3 cobyric acid synthase CobQ compare
MMJJ_RS01355 -2.1 -2.4 UDP-N-acetyl-D-mannosamine dehydrogenase compare
MMJJ_RS08000 -2.1 -8.0 HesA/MoeB/ThiF family protein compare
MMJJ_RS07670 -2.1 -12.0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain compare
MMJJ_RS05415 -2.1 -1.2 hypothetical protein compare
MMJJ_RS04640 -2.1 -12.7 TIGR01177 family methyltransferase compare
MMJJ_RS07995 -2.1 -5.0 molybdenum cofactor biosynthesis protein MoaE compare
MMJJ_RS06930 -2.1 -1.6 type II methionyl aminopeptidase compare
MMJJ_RS07665 -2.1 -13.3 formate dehydrogenase subunit alpha compare
MMJJ_RS08010 -2.1 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMJJ_RS00430 -2.1 -2.3 ribonuclease Z compare
MMJJ_RS01765 -2.1 -6.7 winged helix-turn-helix domain-containing protein compare
MMJJ_RS02040 -2.1 -1.2 Asp-tRNA(Asn) amidotransferase subunit GatC compare
MMJJ_RS02055 -2.0 -8.7 GTP 3',8-cyclase MoaA compare
MMJJ_RS01690 -2.0 -2.6 methanogenesis marker 12 protein compare
MMJJ_RS00550 -2.0 -7.7 AIR synthase-related protein compare
MMJJ_RS05070 -2.0 -1.2 DNA primase catalytic subunit PriS compare
MMJJ_RS06375 -2.0 -2.6 UbiX family flavin prenyltransferase compare
MMJJ_RS03760 -2.0 -2.0 hydrogenase maturation nickel metallochaperone HypA compare
MMJJ_RS04755 -2.0 -8.8 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMJJ_RS07355 -2.0 -5.2 MoaD/ThiS family protein compare
MMJJ_RS05655 -2.0 -6.2 HisA/HisF family protein compare
MMJJ_RS01200 -2.0 -1.9 PRC-barrel domain-containing protein compare
MMJJ_RS06270 -2.0 -7.4 dethiobiotin synthase compare
MMJJ_RS04760 -2.0 -10.9 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMJJ_RS00285 -2.0 -12.2 UPF0254 family protein compare
MMJJ_RS08060 -2.0 -6.9 DNA repair and recombination protein RadA compare
MMJJ_RS09055 -2.0 -8.3 NFACT family protein compare
MMJJ_RS03875 -1.9 -2.2 CBS domain-containing protein compare
MMJJ_RS05260 -1.9 -3.7 ATP-grasp domain-containing protein compare
MMJJ_RS08500 -1.9 -5.1 L-sulfolactate dehydrogenase compare
MMJJ_RS06250 -1.9 -1.4 nicotinamide-nucleotide adenylyltransferase compare
MMJJ_RS08335 -1.9 -1.4 ABC transporter ATP-binding protein compare
MMJJ_RS06175 -1.9 -1.4 DUF1743 domain-containing protein compare
MMJJ_RS04125 -1.9 -8.2 tRNA (guanine(10)-N(2))-dimethyltransferase compare
MMJJ_RS03660 -1.9 -2.1 DUF447 family protein compare
MMJJ_RS07155 -1.9 -7.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMJJ_RS01410 -1.9 -4.9 archaeal proteasome endopeptidase complex subunit beta compare
MMJJ_RS05330 -1.9 -1.0 DNA polymerase II large subunit compare
MMJJ_RS06805 -1.8 -1.7 monovalent cation/H+ antiporter subunit E compare
MMJJ_RS07975 -1.8 -7.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMJJ_RS09085 -1.8 -8.1 minichromosome maintenance protein MCM compare
MMJJ_RS05935 -1.8 -1.3 Era-like GTP-binding protein compare
MMJJ_RS02200 -1.8 -6.7 chorismate pyruvate-lyase family protein compare
MMJJ_RS07875 -1.8 -1.6 FAD-dependent oxidoreductase compare
MMJJ_RS03115 -1.8 -4.5 sulfopyruvate decarboxylase subunit alpha compare
MMJJ_RS04995 -1.8 -3.9 Tfx family DNA-binding protein compare
MMJJ_RS05490 -1.8 -1.5 imidazole glycerol phosphate synthase subunit HisF compare
MMJJ_RS01880 -1.8 -1.7 RlmE family RNA methyltransferase compare
MMJJ_RS06660 -1.8 -6.2 DUF1188 domain-containing protein compare
MMJJ_RS03095 -1.8 -1.7 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase compare
MMJJ_RS00560 -1.8 -2.2 homoisocitrate dehydrogenase compare
MMJJ_RS03160 -1.8 -8.2 winged helix-turn-helix transcriptional regulator compare
MMJJ_RS04750 -1.7 -6.8 5,10-methenyltetrahydromethanopterin hydrogenase compare
MMJJ_RS05810 -1.7 -4.5 precorrin-4 C(11)-methyltransferase compare
MMJJ_RS01830 -1.7 -2.5 tRNA(Ile)(2)-agmatinylcytidine synthase compare
MMJJ_RS02035 -1.7 -4.1 4-hydroxy-tetrahydrodipicolinate synthase compare
MMJJ_RS06835 -1.7 -7.5 4Fe-4S binding protein compare
MMJJ_RS05190 -1.7 -5.1 gamma carbonic anhydrase family protein compare
MMJJ_RS04770 -1.7 -2.5 formate-dependent phosphoribosylglycinamide formyltransferase compare
MMJJ_RS02855 -1.7 -6.7 DEAD/DEAH box helicase compare
MMJJ_RS07425 -1.7 -6.9 MBL fold metallo-hydrolase compare
MMJJ_RS05445 -1.7 -1.1 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMJJ_RS04655 -1.7 -5.0 FAD-dependent oxidoreductase compare
MMJJ_RS07345 -1.7 -5.6 homocysteine biosynthesis protein compare
MMJJ_RS06840 -1.7 -1.1 nickel-dependent hydrogenase large subunit compare
MMJJ_RS03965 -1.7 -1.3 DNA-directed RNA polymerase subunit L compare
MMJJ_RS07955 -1.7 -7.7 ThiF family adenylyltransferase compare
MMJJ_RS04980 -1.6 -3.3 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase compare
MMJJ_RS06760 -1.6 -3.1 Ni-sirohydrochlorin a,c-diamide synthase compare
MMJJ_RS05170 -1.6 -8.7 Nif3-like dinuclear metal center hexameric protein compare
MMJJ_RS08575 -1.6 -2.1 hypothetical protein compare
MMJJ_RS00935 -1.6 -8.7 nickel pincer cofactor biosynthesis protein LarB compare
MMJJ_RS04615 -1.6 -3.5 methanogenesis marker 3 protein compare
MMJJ_RS00600 -1.6 -1.7 hydroxymethylbilane synthase compare
MMJJ_RS06705 -1.6 -3.2 bifunctional NADP phosphatase/NAD kinase compare
MMJJ_RS02935 -1.6 -1.4 DNA-directed RNA polymerase subunit E'' compare
MMJJ_RS05440 -1.6 -6.9 serine/threonine protein kinase compare
MMJJ_RS01010 -1.5 -13.6 right-handed parallel beta-helix repeat-containing protein compare


Specific Phenotypes

For 3 genes in this experiment

For stress Spiramycin in Methanococcus maripaludis JJ

For stress Spiramycin across organisms