Experiment set8IT059 for Klebsiella michiganensis M5al

Compare to:

Mix of RCH2_defined_noCarbon and Fungal_growth_media_mCAFEs_v1_noCarbon; D-Glucose at 55.5 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS11965 -9.5 -6.6 orotidine-5'-phosphate decarboxylase compare
BWI76_RS20355 -9.4 -6.2 colicin V production protein compare
BWI76_RS18950 -9.2 -6.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS02995 -8.8 -6.1 aspartate carbamoyltransferase compare
BWI76_RS24285 -8.7 -6.0 cystathionine beta-lyase compare
BWI76_RS18925 -8.6 -6.0 histidinol dehydrogenase compare
BWI76_RS00980 -8.5 -5.9 PLP-dependent threonine dehydratase compare
BWI76_RS18940 -8.3 -5.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS21265 -8.0 -14.4 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04685 -8.0 -9.5 putative leucine operon leader peptide compare
BWI76_RS04675 -7.8 -7.7 3-isopropylmalate dehydrogenase compare
BWI76_RS18920 -7.8 -5.4 ATP phosphoribosyltransferase compare
BWI76_RS04465 -7.8 -5.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04670 -7.6 -10.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS27385 -7.6 -5.2 orotate phosphoribosyltransferase compare
BWI76_RS05835 -7.4 -5.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS04470 -7.4 -8.8 carbamoyl phosphate synthase large subunit compare
BWI76_RS00990 -7.4 -8.8 ketol-acid reductoisomerase compare
BWI76_RS07065 -7.3 -8.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11860 -7.2 -9.9 anthranilate synthase component I compare
BWI76_RS20965 -7.2 -5.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS08385 -7.2 -4.0 citrate (Si)-synthase compare
BWI76_RS18930 -7.2 -4.9 histidinol-phosphate transaminase compare
BWI76_RS20895 -7.1 -6.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04250 -7.1 -8.4 homoserine kinase compare
BWI76_RS11850 -7.0 -9.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04665 -7.0 -20.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04245 -7.0 -13.4 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04255 -6.9 -9.5 threonine synthase compare
BWI76_RS21475 -6.9 -6.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS05840 -6.9 -6.7 glutamate 5-kinase compare
BWI76_RS09645 -6.8 -2.6 thioredoxin-disulfide reductase compare
BWI76_RS23920 -6.8 -6.1 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS23360 -6.8 -4.7 diaminopimelate decarboxylase compare
BWI76_RS20350 -6.7 -6.7 amidophosphoribosyltransferase compare
BWI76_RS00855 -6.6 -10.1 argininosuccinate lyase compare
BWI76_RS09755 -6.6 -8.7 phosphoserine transaminase compare
BWI76_RS00850 -6.5 -8.8 acetylglutamate kinase compare
BWI76_RS19375 -6.5 -4.2 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS11840 -6.4 -3.1 tryptophan synthase subunit alpha compare
BWI76_RS18955 -6.4 -6.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS23220 -6.4 -8.9 amino-acid N-acetyltransferase compare
BWI76_RS01655 -6.3 -9.7 homoserine O-succinyltransferase compare
BWI76_RS25115 -6.3 -7.1 argininosuccinate synthase compare
BWI76_RS26085 -6.2 -4.1 3-dehydroquinate synthase compare
BWI76_RS23365 -6.2 -5.6 LysR family transcriptional regulator compare
BWI76_RS09910 -6.2 -17.7 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS22760 -6.1 -11.5 sulfite reductase subunit beta compare
BWI76_RS01615 -6.0 -10.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04645 -5.9 -5.7 3-dehydroquinase compare
BWI76_RS03010 -5.9 -7.2 ornithine carbamoyltransferase compare
BWI76_RS11855 -5.9 -6.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS13920 -5.9 -7.3 magnesium-translocating P-type ATPase compare
BWI76_RS00785 -5.8 -8.0 cystathionine gamma-synthase compare
BWI76_RS00845 -5.8 -9.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS25645 -5.8 -8.0 shikimate dehydrogenase compare
BWI76_RS04510 -5.7 -3.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS22755 -5.6 -9.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS10990 -5.6 -5.2 dihydroorotase compare
BWI76_RS18935 -5.6 -9.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS02735 -5.5 -6.6 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00985 -5.5 -7.0 transcriptional regulator IlvY compare
BWI76_RS04160 -5.5 -6.2 phosphoserine phosphatase compare
BWI76_RS22765 -5.4 -12.7 sulfite reductase subunit alpha compare
BWI76_RS00975 -5.3 -7.7 dihydroxy-acid dehydratase compare
BWI76_RS00960 -5.3 -6.2 acetolactate synthase 2 catalytic subunit compare
BWI76_RS00805 -5.3 -3.9 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01200 -5.3 -3.6 diaminopimelate epimerase compare
BWI76_RS00965 -5.3 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS04680 -5.2 -10.6 2-isopropylmalate synthase compare
BWI76_RS04305 -5.1 -2.0 molecular chaperone DnaJ compare
BWI76_RS00835 -4.9 -12.6 phosphoenolpyruvate carboxylase compare
BWI76_RS26000 -4.9 -10.4 aspartate aminotransferase family protein compare
BWI76_RS01610 -4.8 -4.7 phosphoribosylamine--glycine ligase compare
BWI76_RS11845 -4.6 -3.6 tryptophan synthase subunit beta compare
BWI76_RS15115 -4.6 -5.5 MFS transporter compare
BWI76_RS00400 -4.4 -2.9 glutamine synthetase compare
BWI76_RS26055 -4.4 -6.5 siroheme synthase compare
BWI76_RS27390 -4.2 -3.9 ribonuclease PH compare
BWI76_RS09760 -4.2 -4.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20435 -4.1 -2.2 chorismate synthase compare
BWI76_RS07070 -4.1 -6.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS23240 -4.1 -2.8 exonuclease V subunit gamma compare
BWI76_RS15225 -4.1 -3.5 DeoR family transcriptional regulator compare
BWI76_RS20650 -3.9 -2.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS03665 -3.8 -2.8 ABC transporter ATP-binding protein compare
BWI76_RS25065 -3.8 -5.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS21465 -3.8 -2.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04240 -3.8 -3.3 thr operon leader peptide compare
BWI76_RS23265 -3.6 -3.5 hypothetical protein compare
BWI76_RS09660 -3.5 -2.4 DNA translocase FtsK compare
BWI76_RS26460 -3.5 -4.4 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS20640 -3.5 -5.7 cysteine synthase A compare
BWI76_RS23230 -3.5 -2.4 exodeoxyribonuclease V subunit beta compare
BWI76_RS25315 -3.4 -8.9 glutamate synthase large subunit compare
BWI76_RS26940 -3.4 -6.8 transcriptional regulator compare
BWI76_RS01550 -3.4 -7.4 thiamine phosphate synthase compare
BWI76_RS01275 -3.2 -8.1 LysR family transcriptional regulator compare
BWI76_RS25320 -3.1 -6.9 glutamate synthase compare
BWI76_RS01545 -2.9 -4.7 thiamine biosynthesis protein ThiS compare
BWI76_RS25600 -2.9 -1.6 tRNA-Thr compare
BWI76_RS23480 -2.9 -11.5 EAL domain-containing protein compare
BWI76_RS22690 -2.8 -1.8 adenylyl-sulfate kinase compare
BWI76_RS06525 -2.7 -5.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS00180 -2.7 -1.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS17720 -2.6 -1.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS00345 -2.6 -4.5 protein disulfide oxidoreductase DsbA compare
BWI76_RS17975 -2.5 -5.3 tail-specific protease compare
BWI76_RS01800 -2.4 -4.8 glucose-6-phosphate isomerase compare
BWI76_RS09655 -2.4 -4.7 leucine-responsive regulatory protein compare
BWI76_RS22695 -2.3 -5.0 sulfate adenylyltransferase compare
BWI76_RS01555 -2.3 -8.7 phosphomethylpyrimidine synthase ThiC conserved
BWI76_RS27820 -2.3 -2.3 ilvB operon leader peptide IvbL compare
BWI76_RS26455 -2.3 -3.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS01530 -2.2 -6.2 2-iminoacetate synthase ThiH compare
BWI76_RS05015 -2.2 -2.0 transcriptional regulator compare
BWI76_RS03045 -2.1 -1.6 hypothetical protein compare
BWI76_RS21580 -2.1 -2.5 SsrA-binding protein compare
BWI76_RS26570 -2.1 -3.7 anion permease compare
BWI76_RS25335 -2.0 -2.0 stringent starvation protein A compare
BWI76_RS13560 -2.0 -1.5 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS01535 -1.9 -5.4 thiazole synthase compare
BWI76_RS24850 -1.9 -6.8 DeoR family transcriptional regulator compare
BWI76_RS12090 -1.9 -2.5 HNH endonuclease compare
BWI76_RS15835 -1.9 -1.5 hypothetical protein compare
BWI76_RS18165 -1.8 -1.7 NUDIX pyrophosphatase compare
BWI76_RS06395 -1.8 -4.0 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS02530 -1.7 -1.7 tRNA dimethylallyltransferase compare
BWI76_RS13915 -1.7 -3.4 magnesium transport protein MgtC compare
BWI76_RS06530 -1.7 -4.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS19840 -1.7 -1.4 hypothetical protein compare
BWI76_RS20440 -1.7 -1.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS00390 -1.6 -3.8 two-component system sensor histidine kinase NtrB compare
BWI76_RS06765 -1.6 -4.2 transcriptional regulator compare
BWI76_RS01540 -1.6 -1.8 thiamine biosynthesis protein ThiS compare
BWI76_RS17980 -1.6 -3.2 RNA chaperone ProQ compare
BWI76_RS08580 -1.6 -4.0 quinolinate synthetase compare
BWI76_RS19670 -1.5 -2.9 S-formylglutathione hydrolase compare
BWI76_RS01210 -1.5 -1.9 tyrosine recombinase XerC compare
BWI76_RS04845 -1.5 -4.1 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS24075 -1.5 -3.6 glutathione synthase compare
BWI76_RS21480 -1.5 -2.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS05450 -1.5 -1.6 ribonuclease HI compare
BWI76_RS24900 -1.5 -1.7 DeoR family transcriptional regulator compare
BWI76_RS05200 -1.5 -2.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09190 -1.4 -2.7 hypothetical protein compare
BWI76_RS01925 -1.4 -7.0 aromatic amino acid aminotransferase compare
BWI76_RS15850 -1.4 -0.8 DUF1317 domain-containing protein compare
BWI76_RS15840 -1.4 -2.3 prophage protein compare
BWI76_RS10755 -1.3 -1.6 pyrimidine utilization flavin reductase protein F compare
BWI76_RS21350 -1.3 -2.4 anti-RNA polymerase sigma factor SigE compare
BWI76_RS09650 -1.3 -4.0 hypothetical protein compare
BWI76_RS02410 -1.3 -1.8 EF-P beta-lysylation protein EpmB compare
BWI76_RS19690 -1.3 -1.2 LysR family transcriptional regulator compare
BWI76_RS22700 -1.3 -4.1 sulfate adenylyltransferase subunit 2 compare
BWI76_RS25280 -1.3 -2.0 RNase adaptor protein RapZ compare
BWI76_RS19380 -1.3 -2.5 hydroxyethylthiazole kinase compare
BWI76_RS01630 -1.3 -1.3 16S ribosomal RNA compare
BWI76_RS13595 -1.2 -2.3 transcriptional regulator compare
BWI76_RS21360 -1.2 -3.4 L-aspartate oxidase compare
BWI76_RS26395 -1.2 -2.8 cell division protein FtsE compare
BWI76_RS20995 -1.2 -3.5 RNA degradosome polyphosphate kinase compare
BWI76_RS25960 -1.2 -2.9 NUDIX hydrolase compare
BWI76_RS27430 -1.2 -1.0 (p)ppGpp synthetase compare
BWI76_RS00970 -1.2 -1.5 branched chain amino acid aminotransferase compare
BWI76_RS20380 -1.2 -1.2 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS21690 -1.2 -1.7 hypothetical protein compare
BWI76_RS10950 -1.2 -1.7 MFS transporter compare
BWI76_RS21375 -1.2 -1.6 autonomous glycyl radical cofactor GrcA compare
BWI76_RS00025 -1.2 -0.9 hypothetical protein compare
BWI76_RS06185 -1.2 -5.9 shikimate kinase II compare
BWI76_RS01280 -1.1 -4.9 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS24465 -1.1 -5.8 adenylate cyclase compare
BWI76_RS16965 -1.1 -2.2 murein lipoprotein compare
BWI76_RS11130 -1.1 -3.9 PTS glucose transporter subunit IIBC compare
BWI76_RS22705 -1.1 -3.9 siroheme synthase compare
BWI76_RS07645 -1.1 -1.5 short-chain dehydrogenase/reductase compare
BWI76_RS18580 -1.1 -1.9 hypothetical protein compare
BWI76_RS21070 -1.1 -0.8 outer membrane protein assembly factor BamB compare
BWI76_RS05075 -1.1 -0.9 type II secretion system protein GspG compare
BWI76_RS11775 -1.1 -1.5 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS23120 -1.1 -2.1 propanediol dehydratase medium subunit compare
BWI76_RS22485 -1.1 -2.6 hypothetical protein compare
BWI76_RS15830 -1.1 -1.9 hypothetical protein compare
BWI76_RS00385 -1.1 -5.0 nitrogen assimilation regulatory protein compare
BWI76_RS08530 -1.1 -1.9 protein TolA compare
BWI76_RS19025 -1.1 -5.8 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS06770 -1.0 -6.2 Hha toxicity attenuator compare
BWI76_RS26175 -1.0 -2.4 DeoR/GlpR family transcriptional regulator compare
BWI76_RS08535 -1.0 -0.9 translocation protein TolB compare
BWI76_RS23915 -1.0 -1.9 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS22645 -1.0 -3.8 RNA polymerase sigma factor RpoS compare
BWI76_RS23070 -1.0 -3.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
BWI76_RS13545 -1.0 -1.3 N-acetyltransferase compare
BWI76_RS04515 -1.0 -1.2 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS01350 -1.0 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS26045 -1.0 -1.6 nitrite reductase small subunit compare
BWI76_RS21505 -1.0 -1.1 hypothetical protein compare
BWI76_RS02225 -0.9 -2.5 phosphonate C-P lyase system protein PhnG compare
BWI76_RS24025 -0.9 -4.6 agmatinase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Glucose in Klebsiella michiganensis M5al

For carbon source D-Glucose across organisms