Experiment set8IT054 for Klebsiella michiganensis M5al

Compare to:

D-Glucose 20 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS11965 -9.7 -6.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS20355 -9.6 -6.2 colicin V production protein compare
BWI76_RS05835 -7.7 -5.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS18940 -7.5 -7.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18930 -7.5 -5.1 histidinol-phosphate transaminase compare
BWI76_RS02995 -7.3 -9.7 aspartate carbamoyltransferase compare
BWI76_RS09645 -7.0 -2.6 thioredoxin-disulfide reductase compare
BWI76_RS18935 -7.0 -7.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS18925 -6.7 -7.6 histidinol dehydrogenase compare
BWI76_RS27385 -6.6 -7.9 orotate phosphoribosyltransferase compare
BWI76_RS04470 -6.4 -12.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS26085 -6.4 -4.1 3-dehydroquinate synthase compare
BWI76_RS04250 -6.4 -10.0 homoserine kinase compare
BWI76_RS21475 -6.2 -7.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS20895 -6.0 -5.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04160 -6.0 -8.5 phosphoserine phosphatase compare
BWI76_RS09760 -5.9 -5.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS24285 -5.9 -6.7 cystathionine beta-lyase compare
BWI76_RS09910 -5.8 -17.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04255 -5.8 -9.8 threonine synthase compare
BWI76_RS11840 -5.8 -4.7 tryptophan synthase subunit alpha compare
BWI76_RS00855 -5.8 -7.4 argininosuccinate lyase compare
BWI76_RS04670 -5.8 -9.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS02735 -5.8 -6.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS21265 -5.8 -13.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS08385 -5.6 -5.9 citrate (Si)-synthase compare
BWI76_RS18950 -5.6 -3.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS24400 -5.6 -9.4 outer membrane channel protein TolC compare
BWI76_RS04675 -5.6 -7.4 3-isopropylmalate dehydrogenase compare
BWI76_RS00835 -5.6 -14.9 phosphoenolpyruvate carboxylase compare
BWI76_RS20350 -5.5 -7.1 amidophosphoribosyltransferase compare
BWI76_RS09755 -5.4 -7.5 phosphoserine transaminase compare
BWI76_RS01615 -5.4 -9.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS22690 -5.4 -6.4 adenylyl-sulfate kinase compare
BWI76_RS05015 -5.4 -4.2 transcriptional regulator compare
BWI76_RS07065 -5.4 -5.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04465 -5.3 -5.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS01655 -5.3 -7.5 homoserine O-succinyltransferase compare
BWI76_RS00785 -5.3 -7.2 cystathionine gamma-synthase compare
BWI76_RS18920 -5.2 -5.0 ATP phosphoribosyltransferase compare
BWI76_RS04645 -5.2 -7.6 3-dehydroquinase compare
BWI76_RS04240 -5.1 -2.1 thr operon leader peptide compare
BWI76_RS23220 -5.1 -7.5 amino-acid N-acetyltransferase compare
BWI76_RS04245 -5.0 -14.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04665 -4.9 -17.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS22755 -4.9 -9.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00850 -4.9 -7.8 acetylglutamate kinase compare
BWI76_RS11855 -4.8 -5.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS10990 -4.8 -5.2 dihydroorotase compare
BWI76_RS04680 -4.8 -8.8 2-isopropylmalate synthase compare
BWI76_RS00980 -4.8 -10.9 PLP-dependent threonine dehydratase compare
BWI76_RS00805 -4.8 -4.7 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18955 -4.8 -7.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS07070 -4.7 -6.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20965 -4.7 -3.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04685 -4.7 -11.9 putative leucine operon leader peptide compare
BWI76_RS03010 -4.6 -7.2 ornithine carbamoyltransferase compare
BWI76_RS11860 -4.6 -8.8 anthranilate synthase component I compare
BWI76_RS00985 -4.6 -7.0 transcriptional regulator IlvY compare
BWI76_RS00400 -4.6 -2.9 glutamine synthetase compare
BWI76_RS23920 -4.5 -5.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00990 -4.5 -5.8 ketol-acid reductoisomerase compare
BWI76_RS11850 -4.5 -8.4 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS22765 -4.3 -14.3 sulfite reductase subunit alpha compare
BWI76_RS00845 -4.3 -9.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01610 -4.3 -5.4 phosphoribosylamine--glycine ligase compare
BWI76_RS20435 -4.3 -2.2 chorismate synthase compare
BWI76_RS23360 -4.3 -4.7 diaminopimelate decarboxylase compare
BWI76_RS25645 -4.3 -7.8 shikimate dehydrogenase compare
BWI76_RS01200 -4.3 -3.9 diaminopimelate epimerase compare
BWI76_RS15115 -4.2 -7.0 MFS transporter compare
BWI76_RS04510 -4.2 -3.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS00975 -4.2 -7.4 dihydroxy-acid dehydratase compare
BWI76_RS00180 -4.2 -2.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS11845 -4.2 -4.9 tryptophan synthase subunit beta compare
BWI76_RS23265 -4.1 -4.8 hypothetical protein compare
BWI76_RS01800 -4.1 -4.4 glucose-6-phosphate isomerase compare
BWI76_RS20650 -4.1 -2.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS05840 -4.0 -6.4 glutamate 5-kinase compare
BWI76_RS22760 -4.0 -9.6 sulfite reductase subunit beta compare
BWI76_RS25115 -3.9 -4.7 argininosuccinate synthase compare
BWI76_RS23240 -3.9 -3.8 exonuclease V subunit gamma compare
BWI76_RS21465 -3.9 -6.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS13920 -3.8 -6.3 magnesium-translocating P-type ATPase compare
BWI76_RS05200 -3.8 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09660 -3.7 -2.6 DNA translocase FtsK compare
BWI76_RS23365 -3.7 -4.1 LysR family transcriptional regulator compare
BWI76_RS17975 -3.4 -7.1 tail-specific protease compare
BWI76_RS00965 -3.4 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS25320 -3.2 -8.2 glutamate synthase compare
BWI76_RS23230 -3.2 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS25065 -3.1 -5.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00390 -3.0 -6.8 two-component system sensor histidine kinase NtrB compare
BWI76_RS27390 -3.0 -2.9 ribonuclease PH compare
BWI76_RS25315 -3.0 -10.3 glutamate synthase large subunit compare
BWI76_RS26055 -3.0 -7.5 siroheme synthase compare
BWI76_RS06765 -2.9 -4.2 transcriptional regulator compare
BWI76_RS23480 -2.8 -13.5 EAL domain-containing protein compare
BWI76_RS02530 -2.8 -3.1 tRNA dimethylallyltransferase compare
BWI76_RS02410 -2.7 -3.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS26000 -2.7 -5.7 aspartate aminotransferase family protein compare
BWI76_RS21070 -2.7 -2.4 outer membrane protein assembly factor BamB compare
BWI76_RS15225 -2.6 -2.6 DeoR family transcriptional regulator compare
BWI76_RS26570 -2.6 -3.8 anion permease compare
BWI76_RS06775 -2.5 -14.5 multidrug efflux RND transporter permease subunit compare
BWI76_RS06780 -2.5 -6.7 MexE family multidrug efflux RND transporter periplasmic adaptor subunit compare
BWI76_RS06525 -2.4 -8.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS12090 -2.2 -2.9 HNH endonuclease compare
BWI76_RS00345 -2.2 -3.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS00385 -2.2 -9.7 nitrogen assimilation regulatory protein compare
BWI76_RS05120 -2.2 -8.1 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS01350 -2.1 -1.6 NAD(P)H-flavin reductase compare
BWI76_RS06530 -2.1 -7.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS17980 -2.1 -2.8 RNA chaperone ProQ compare
BWI76_RS09655 -2.1 -4.4 leucine-responsive regulatory protein compare
BWI76_RS24900 -2.0 -2.6 DeoR family transcriptional regulator compare
BWI76_RS16965 -1.9 -3.7 murein lipoprotein compare
BWI76_RS13915 -1.9 -3.7 magnesium transport protein MgtC compare
BWI76_RS00960 -1.9 -4.0 acetolactate synthase 2 catalytic subunit compare
BWI76_RS20360 -1.8 -1.6 cell division protein DedD compare
BWI76_RS27310 -1.8 -8.2 glycosyltransferase compare
BWI76_RS21370 -1.8 -3.2 ATP-dependent RNA helicase SrmB compare
BWI76_RS25920 -1.8 -1.7 peptidylprolyl isomerase compare
BWI76_RS21140 -1.7 -3.3 molecular chaperone HscA compare
BWI76_RS20640 -1.7 -3.9 cysteine synthase A compare
BWI76_RS15850 -1.7 -1.7 DUF1317 domain-containing protein compare
BWI76_RS25070 -1.7 -1.9 hypothetical protein compare
BWI76_RS27430 -1.6 -1.4 (p)ppGpp synthetase compare
BWI76_RS23895 -1.6 -1.4 Xaa-Pro aminopeptidase compare
BWI76_RS04845 -1.6 -7.4 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS26200 -1.6 -5.3 starch synthase compare
BWI76_RS20995 -1.6 -4.3 RNA degradosome polyphosphate kinase compare
BWI76_RS22805 -1.6 -8.2 GTP diphosphokinase compare
BWI76_RS04705 -1.6 -7.1 DNA-binding transcriptional regulator FruR compare
BWI76_RS16485 -1.5 -2.1 ribonuclease T compare
BWI76_RS08580 -1.5 -3.1 quinolinate synthetase compare
BWI76_RS15840 -1.5 -2.2 prophage protein compare
BWI76_RS19375 -1.5 -2.4 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS24025 -1.5 -7.8 agmatinase compare
BWI76_RS08530 -1.4 -2.6 protein TolA compare
BWI76_RS08525 -1.4 -4.0 colicin transporter compare
BWI76_RS20970 -1.3 -1.7 phosphoribosylglycinamide formyltransferase compare
BWI76_RS19845 -1.3 -5.2 phosphatase compare
BWI76_RS25060 -1.3 -2.5 lipoprotein NlpI compare
BWI76_RS20440 -1.3 -1.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS25335 -1.3 -3.5 stringent starvation protein A compare
BWI76_RS00600 -1.3 -5.5 LacI family transcriptional regulator compare
BWI76_RS18715 -1.3 -4.9 hypothetical protein compare
BWI76_RS18710 -1.2 -8.1 GGDEF-domain containing protein compare
BWI76_RS09530 -1.2 -1.4 hypothetical protein compare
BWI76_RS17720 -1.2 -1.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS11130 -1.2 -5.4 PTS glucose transporter subunit IIBC compare
BWI76_RS09650 -1.2 -4.3 hypothetical protein compare
BWI76_RS21675 -1.2 -1.6 hypothetical protein compare
BWI76_RS01210 -1.2 -1.7 tyrosine recombinase XerC compare
BWI76_RS06770 -1.1 -6.2 Hha toxicity attenuator compare
BWI76_RS15110 -1.1 -7.4 putative excinuclease ABC subunit A compare
BWI76_RS13595 -1.1 -2.6 transcriptional regulator compare
BWI76_RS16425 -1.1 -1.0 hypothetical protein compare
BWI76_RS23320 -1.1 -1.6 hypothetical protein compare
BWI76_RS22695 -1.1 -3.9 sulfate adenylyltransferase compare
BWI76_RS15830 -1.1 -1.8 hypothetical protein compare
BWI76_RS26580 -1.1 -5.7 universal stress protein A compare
BWI76_RS26890 -1.1 -1.4 hypothetical protein compare
BWI76_RS26620 -1.1 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS19690 -1.1 -2.8 LysR family transcriptional regulator compare
BWI76_RS25505 -1.1 -4.7 RNase E specificity factor CsrD compare
BWI76_RS21000 -1.1 -5.8 exopolyphosphatase compare
BWI76_RS05260 -1.1 -1.5 chaperone compare
BWI76_RS21480 -1.1 -1.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS01545 -1.0 -3.4 thiamine biosynthesis protein ThiS compare
BWI76_RS01330 -1.0 -2.4 twin-arginine translocase subunit TatC compare
BWI76_RS21350 -1.0 -1.8 anti-RNA polymerase sigma factor SigE compare
BWI76_RS01775 -1.0 -1.0 hypothetical protein compare
BWI76_RS09870 -1.0 -5.3 aromatic amino acid aminotransferase compare
BWI76_RS23270 -1.0 -5.4 phosphoenolpyruvate--protein phosphotransferase PtsP compare
BWI76_RS04570 -1.0 -3.4 RNA polymerase-associated protein RapA compare
BWI76_RS26590 -1.0 -2.0 transcriptional regulator compare
BWI76_RS18755 -1.0 -1.2 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS25300 -1.0 -1.9 hybrid sensor histidine kinase/response regulator compare
BWI76_RS27440 -1.0 -2.2 DNA helicase RecG compare
BWI76_RS26460 -1.0 -3.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS24635 -1.0 -2.9 autoinducer-2 (AI-2) modifying protein LsrG compare
BWI76_RS00140 -1.0 -1.1 phosphate transport system regulator PhoU compare
BWI76_RS01275 -1.0 -3.0 LysR family transcriptional regulator compare
BWI76_RS05355 -1.0 -3.8 methionine ABC transporter substrate-binding protein MetQ compare
BWI76_RS02855 -1.0 -0.9 cytochrome B562 compare
BWI76_RS21450 -1.0 -1.3 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS20230 -0.9 -1.6 hypothetical protein compare
BWI76_RS01535 -0.9 -3.6 thiazole synthase compare
BWI76_RS22700 -0.9 -2.7 sulfate adenylyltransferase subunit 2 compare
BWI76_RS25600 -0.9 -0.9 tRNA-Thr compare
BWI76_RS26175 -0.9 -2.8 DeoR/GlpR family transcriptional regulator compare
BWI76_RS17110 -0.9 -1.6 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS23485 -0.9 -4.1 hypothetical protein compare
BWI76_RS02610 -0.9 -3.7 transcriptional regulator compare
BWI76_RS04100 -0.9 -2.9 peptide chain release factor 3 compare
BWI76_RS22650 -0.9 -3.5 lipoprotein NlpD compare
BWI76_RS09610 -0.9 -1.5 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS19685 -0.9 -3.5 lysine transporter compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source D-Glucose across organisms