Experiment set8IT046 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Leucine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_71 -5.5 -6.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4047 -4.6 -6.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4825 -4.6 -9.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_2189 -4.4 -5.2 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_4826 -4.4 -8.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3842 -4.2 -5.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4764 -4.2 -7.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_479 -4.2 -4.8 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_4153 -4.1 -2.6 Sensory box histidine kinase compare
Pf6N2E2_2574 -3.9 -2.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_3062 -3.9 -5.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2193 -3.7 -8.5 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) conserved
Pf6N2E2_4743 -3.7 -1.4 hypothetical protein compare
Pf6N2E2_5156 -3.7 -2.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4048 -3.6 -8.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -3.6 -6.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3667 -3.6 -2.3 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3839 -3.4 -5.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_482 -3.4 -2.5 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_3630 -3.3 -5.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2675 -3.2 -1.2 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2258 -3.2 -9.8 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2827 -3.2 -1.6 hypothetical protein compare
Pf6N2E2_4759 -3.1 -11.4 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_481 -3.1 -8.1 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) conserved
Pf6N2E2_5175 -3.1 -11.6 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3349 -3.1 -4.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2194 -3.0 -9.5 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) conserved
Pf6N2E2_302 -3.0 -6.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2218 -3.0 -6.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4418 -2.9 -1.1 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3932 -2.9 -5.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4752 -2.8 -11.5 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_477 -2.8 -5.4 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_3783 -2.8 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3505 -2.8 -2.1 Translation initiation factor SUI1-related protein compare
Pf6N2E2_2192 -2.7 -8.8 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) conserved
Pf6N2E2_3271 -2.7 -2.8 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_279 -2.7 -6.4 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_2191 -2.7 -10.7 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) conserved
Pf6N2E2_4963 -2.7 -2.2 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_2217 -2.6 -5.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_480 -2.6 -9.8 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4) (from data) conserved
Pf6N2E2_4763 -2.6 -7.2 Biotin synthesis protein BioC compare
Pf6N2E2_3248 -2.6 -3.5 Probable transmembrane protein compare
Pf6N2E2_3252 -2.6 -6.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5536 -2.5 -1.7 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3610 -2.5 -4.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_1676 -2.5 -2.6 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_4761 -2.5 -7.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4009 -2.4 -8.6 GGDEF domain protein compare
Pf6N2E2_3253 -2.4 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_5579 -2.3 -6.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5006 -2.3 -8.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4612 -2.2 -4.4 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_1056 -2.2 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3763 -2.2 -3.0 hypothetical protein compare
Pf6N2E2_4611 -2.2 -4.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4564 -2.2 -6.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3869 -2.2 -8.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2073 -2.2 -7.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3942 -2.2 -7.3 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_309 -2.2 -1.5 FIG00957702: hypothetical protein compare
Pf6N2E2_2124 -2.1 -2.1 Mg(2+) transport ATPase protein C compare
Pf6N2E2_5176 -2.1 -6.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4204 -2.1 -1.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4372 -2.1 -4.2 FIG00460773: hypothetical protein compare
Pf6N2E2_2588 -2.1 -3.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_2852 -2.1 -7.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_3940 -2.0 -6.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2752 -2.0 -7.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3282 -2.0 -2.3 FIG005080: Possible exported protein compare
Pf6N2E2_4631 -2.0 -7.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3782 -2.0 -2.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3984 -1.9 -7.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2186 -1.9 -5.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5242 -1.9 -2.5 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2549 -1.9 -2.1 hypothetical protein compare
Pf6N2E2_698 -1.9 -2.9 Heme d1 biosynthesis protein NirH compare
Pf6N2E2_5780 -1.9 -7.7 Periplasmic protease compare
Pf6N2E2_613 -1.9 -1.7 lipoprotein, putative compare
Pf6N2E2_3665 -1.8 -1.1 serine/threonine protein kinase compare
Pf6N2E2_1147 -1.8 -1.7 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_2756 -1.8 -6.0 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2277 -1.8 -1.7 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_70 -1.8 -3.3 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3460 -1.7 -1.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2509 -1.7 -1.9 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_5339 -1.7 -5.4 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_229 -1.7 -2.8 Putative fumarylacetoacetate (FAA) hydrolase compare
Pf6N2E2_2081 -1.7 -1.7 putative exported protein compare
Pf6N2E2_4987 -1.7 -1.3 MaoC-like domain protein compare
Pf6N2E2_3870 -1.7 -2.5 hypothetical protein compare
Pf6N2E2_2925 -1.7 -2.8 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 1 LivG (from data) compare
Pf6N2E2_1323 -1.7 -1.7 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_2753 -1.7 -3.1 HtrA protease/chaperone protein compare
Pf6N2E2_1886 -1.6 -1.7 hypothetical protein compare
Pf6N2E2_4762 -1.6 -1.9 Biotin synthesis protein BioH compare
Pf6N2E2_1401 -1.6 -5.5 FIG00955631: hypothetical protein compare
Pf6N2E2_178 -1.6 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_1294 -1.6 -2.7 Carbon starvation protein A compare
Pf6N2E2_5252 -1.6 -1.9 FIG00956396: hypothetical protein compare
Pf6N2E2_1381 -1.6 -5.8 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_1116 -1.6 -1.8 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_5728 -1.6 -3.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_1081 -1.6 -1.8 probable membrane protein YPO3302 compare
Pf6N2E2_4579 -1.6 -1.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4454 -1.5 -5.0 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3941 -1.5 -2.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_4636 -1.5 -4.3 periplasmic binding protein, putative compare
Pf6N2E2_2926 -1.5 -3.9 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 2 LivF (from data) conserved
Pf6N2E2_2527 -1.5 -4.5 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3085 -1.5 -2.2 FIG00954614: hypothetical protein compare
Pf6N2E2_4052 -1.5 -1.4 FIG00955481: hypothetical protein compare
Pf6N2E2_1402 -1.5 -5.0 hypothetical protein compare
Pf6N2E2_5986 -1.4 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5177 -1.4 -5.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3578 -1.4 -6.9 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) conserved
Pf6N2E2_127 -1.4 -1.5 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_1400 -1.4 -7.2 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2143 -1.4 -4.1 Uncharacterized GST-like protein yncG compare
Pf6N2E2_5705 -1.4 -2.0 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_1932 -1.4 -3.6 Transcriptional regulator, IclR family compare
Pf6N2E2_1283 -1.4 -1.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5723 -1.4 -5.9 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5527 -1.4 -1.7 Cold shock protein CspC compare
Pf6N2E2_189 -1.4 -2.9 regulatory protein, putative compare
Pf6N2E2_2106 -1.3 -1.6 hypothetical protein compare
Pf6N2E2_5178 -1.3 -1.7 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_2514 -1.3 -4.2 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_1784 -1.3 -1.4 Methyl-accepting chemotaxis protein compare
Pf6N2E2_771 -1.3 -3.6 Ribosyl nicotinamide transporter, PnuC-like compare
Pf6N2E2_6022 -1.3 -1.8 StbE replicon stabilization toxin compare
Pf6N2E2_624 -1.3 -3.0 hypothetical protein PA3071 compare
Pf6N2E2_2402 -1.3 -1.7 hypothetical protein compare
Pf6N2E2_3687 -1.3 -2.2 FIG00959437: hypothetical protein compare
Pf6N2E2_5830 -1.3 -2.3 FIG00960829: hypothetical protein compare
Pf6N2E2_1040 -1.3 -1.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3579 -1.3 -6.6 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) conserved
Pf6N2E2_3580 -1.3 -6.4 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) conserved
Pf6N2E2_2706 -1.3 -2.0 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_2530 -1.2 -6.1 Sensory box/GGDEF family protein compare
Pf6N2E2_5157 -1.2 -5.4 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4162 -1.2 -2.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_3521 -1.2 -5.9 Sensor histidine kinase/response regulator compare
Pf6N2E2_2921 -1.2 -6.0 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK (from data) conserved
Pf6N2E2_3834 -1.2 -3.9 Lipoprotein NlpD compare
Pf6N2E2_478 -1.2 -2.5 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) conserved
Pf6N2E2_4638 -1.2 -2.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5338 -1.2 -4.8 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_623 -1.2 -1.4 FIG00954674: hypothetical protein compare
Pf6N2E2_5331 -1.2 -3.3 ATPase, AFG1 family compare
Pf6N2E2_1718 -1.2 -2.3 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_4453 -1.2 -8.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_160 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_2488 -1.2 -1.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3132 -1.2 -3.0 FIG00954548: hypothetical protein compare
Pf6N2E2_5807 -1.2 -3.3 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
Pf6N2E2_3677 -1.2 -6.4 Sensory box/GGDEF family protein compare
Pf6N2E2_2924 -1.2 -6.0 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, permease component 2 LivM (from data) conserved
Pf6N2E2_3397 -1.2 -1.9 Phage protein compare
Pf6N2E2_4994 -1.2 -3.4 Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) compare
Pf6N2E2_5014 -1.2 -1.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3885 -1.2 -1.7 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2696 -1.2 -6.4 Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) conserved
Pf6N2E2_5956 -1.2 -4.2 FIG004453: protein YceG like compare
Pf6N2E2_1548 -1.2 -1.8 Lactoylglutathione lyase compare
Pf6N2E2_3844 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_2420 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_5413 -1.1 -2.3 Glutaredoxin NrdH compare
Pf6N2E2_4160 -1.1 -1.2 Cytochrome c5 compare
Pf6N2E2_5158 -1.1 -2.4 FIG00954153: hypothetical protein compare
Pf6N2E2_2479 -1.1 -1.4 Transcription elongation factor GreB compare
Pf6N2E2_533 -1.1 -2.9 Na(+) H(+) antiporter subunit G compare
Pf6N2E2_4969 -1.1 -0.9 hypothetical protein compare
Pf6N2E2_1490 -1.1 -1.4 hypothetical protein compare
Pf6N2E2_6063 -1.1 -4.3 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_1136 -1.1 -1.0 Transcriptional regulator, TetR family compare
Pf6N2E2_1652 -1.1 -2.3 Transcriptional regulator, TetR family compare
Pf6N2E2_5943 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_4159 -1.1 -2.1 Cytochrome c4 compare
Pf6N2E2_1735 -1.0 -2.4 PhnB protein compare
Pf6N2E2_1385 -1.0 -2.0 FIG00956261: hypothetical protein compare
Pf6N2E2_2886 -1.0 -7.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5672 -1.0 -1.7 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78) compare
Pf6N2E2_3027 -1.0 -0.9 Baseplate assembly protein V compare
Pf6N2E2_2069 -1.0 -1.2 FIG00953703: hypothetical protein compare
Pf6N2E2_3122 -1.0 -1.0 Chemotaxis signal transduction protein compare
Pf6N2E2_5727 -1.0 -3.8 FIG00955360: hypothetical protein compare
Pf6N2E2_3762 -1.0 -3.4 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_4587 -1.0 -2.6 Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) compare
Pf6N2E2_5277 -1.0 -3.7 FIG00953110: hypothetical protein compare
Pf6N2E2_3340 -1.0 -5.6 Fructose repressor FruR, LacI family compare
Pf6N2E2_5638 -1.0 -4.0 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_2967 -1.0 -1.5 Cold shock protein CspA compare
Pf6N2E2_827 -1.0 -1.6 probable dioxygenase compare
Pf6N2E2_4206 -1.0 -1.1 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_438 -1.0 -3.2 hypothetical protein compare
Pf6N2E2_6140 -1.0 -0.6 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_1870 -1.0 -0.7 hypothetical protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Leucine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Leucine across organisms