Experiment set8IT041 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Asparagine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.4 -6.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -5.8 -5.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4596 -5.7 -8.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3782 -5.6 -3.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_77 -5.4 -5.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4825 -5.4 -9.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3253 -5.3 -6.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4047 -5.3 -6.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3630 -5.1 -7.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3842 -5.1 -6.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3783 -4.9 -5.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5176 -4.9 -9.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3610 -4.8 -7.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5175 -4.8 -15.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4087 -4.7 -12.5 L-asparaginase (EC 3.5.1.1) (from data) conserved
Pf6N2E2_4826 -4.7 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_302 -4.6 -6.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4153 -4.5 -3.1 Sensory box histidine kinase compare
Pf6N2E2_3248 -4.5 -5.8 Probable transmembrane protein compare
Pf6N2E2_4564 -4.5 -10.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3940 -4.5 -13.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -4.2 -9.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4086 -4.1 -19.6 sodium/alanine transporter conserved
Pf6N2E2_5177 -4.1 -11.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2186 -4.0 -8.0 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2073 -4.0 -7.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_66 -3.9 -9.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_5156 -3.9 -2.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3839 -3.8 -6.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3841 -3.8 -6.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_64 -3.7 -3.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4638 -3.6 -3.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3252 -3.6 -8.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2753 -3.4 -3.3 HtrA protease/chaperone protein compare
Pf6N2E2_2277 -3.2 -4.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5316 -3.1 -3.0 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3763 -3.0 -3.5 hypothetical protein compare
Pf6N2E2_2074 -3.0 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_1400 -3.0 -10.1 Sensory box histidine kinase/response regulator compare
Pf6N2E2_3932 -2.9 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3251 -2.9 -11.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5579 -2.8 -7.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5014 -2.8 -2.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2218 -2.7 -5.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2465 -2.6 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_1402 -2.5 -8.6 hypothetical protein compare
Pf6N2E2_1932 -2.5 -7.1 Transcriptional regulator, IclR family compare
Pf6N2E2_63 -2.5 -3.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3170 -2.4 -6.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5728 -2.4 -3.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_1381 -2.3 -7.9 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_4187 -2.3 -5.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4797 -2.2 -3.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5950 -2.2 -4.9 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3984 -2.2 -12.2 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5006 -2.1 -8.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3611 -2.1 -1.6 HflC protein compare
Pf6N2E2_5258 -2.1 -9.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4009 -2.1 -11.6 GGDEF domain protein compare
Pf6N2E2_4084 -2.1 -7.0 Transcriptional regulator compare
Pf6N2E2_178 -2.0 -2.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_1404 -2.0 -3.1 Nitrous oxide reductase maturation transmembrane protein NosY compare
Pf6N2E2_5527 -2.0 -2.6 Cold shock protein CspC compare
Pf6N2E2_5257 -2.0 -10.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4362 -1.9 -4.3 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_5103 -1.9 -1.3 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4453 -1.9 -13.5 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5567 -1.9 -2.9 Glutamate Aspartate transport ATP-binding protein GltL (TC 3.A.1.3.4) compare
Pf6N2E2_3060 -1.8 -3.5 Outer membrane protein H precursor compare
Pf6N2E2_5405 -1.8 -5.0 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_3062 -1.8 -4.2 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4416 -1.8 -3.5 Tyrosine recombinase XerC compare
Pf6N2E2_3661 -1.8 -5.2 hypothetical protein compare
Pf6N2E2_4611 -1.8 -4.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5219 -1.7 -8.5 FIG140336: TPR domain protein compare
Pf6N2E2_2217 -1.7 -4.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3349 -1.7 -2.8 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4276 -1.7 -4.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5780 -1.7 -7.6 Periplasmic protease compare
Pf6N2E2_3942 -1.7 -10.2 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_760 -1.6 -9.2 Na+/H+ antiporter NhaB compare
Pf6N2E2_3300 -1.6 -4.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2310 -1.6 -8.2 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3264 -1.6 -2.2 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3835 -1.6 -4.1 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3762 -1.6 -6.9 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_3667 -1.6 -1.4 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3869 -1.6 -10.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2527 -1.5 -5.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_2574 -1.5 -1.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_2473 -1.5 -1.7 Major outer membrane lipoprotein I compare
Pf6N2E2_5841 -1.5 -1.6 GlcG protein compare
Pf6N2E2_5640 -1.5 -2.1 FIG00955597: hypothetical protein compare
Pf6N2E2_4759 -1.5 -10.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_70 -1.5 -4.1 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_5242 -1.4 -2.4 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5705 -1.4 -2.5 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2317 -1.4 -4.5 Putative analog of CcoH, COG3198 compare
Pf6N2E2_2507 -1.4 -4.1 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2510 -1.4 -3.5 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3941 -1.3 -2.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_1691 -1.3 -2.5 hypothetical protein compare
Pf6N2E2_2311 -1.3 -5.7 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_3283 -1.2 -5.3 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_3271 -1.2 -2.5 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3460 -1.2 -1.6 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3659 -1.2 -4.9 Protein fixF compare
Pf6N2E2_2080 -1.2 -1.3 hypothetical protein compare
Pf6N2E2_2513 -1.2 -2.8 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_1656 -1.2 -2.1 hypothetical protein compare
Pf6N2E2_4159 -1.2 -4.0 Cytochrome c4 compare
Pf6N2E2_2318 -1.2 -6.3 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_6099 -1.2 -1.6 tRNA-Glu-TTC compare
Pf6N2E2_4418 -1.2 -0.9 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_89 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_2754 -1.2 -3.1 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_2503 -1.2 -1.8 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_4413 -1.1 -3.1 FIG004064: hypothetical protein compare
Pf6N2E2_4417 -1.1 -3.6 Protein of unknown function DUF484 compare
Pf6N2E2_5252 -1.1 -1.9 FIG00956396: hypothetical protein compare
Pf6N2E2_5130 -1.1 -2.9 hypothetical protein compare
Pf6N2E2_2320 -1.1 -2.1 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3521 -1.1 -6.1 Sensor histidine kinase/response regulator compare
Pf6N2E2_1317 -1.1 -3.5 P-hydroxyphenylacetate hydroxylase C2:oxygenase component compare
Pf6N2E2_3938 -1.1 -7.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_671 -1.1 -3.7 2-methylaconitate racemase compare
Pf6N2E2_4097 -1.1 -7.5 FIG00953365: hypothetical protein compare
Pf6N2E2_4451 -1.1 -4.8 FIG139438: lipoprotein B compare
Pf6N2E2_5339 -1.0 -4.8 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_5609 -1.0 -4.4 DNA-binding response regulator ColR compare
Pf6N2E2_510 -1.0 -6.4 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_3665 -1.0 -1.1 serine/threonine protein kinase compare
Pf6N2E2_3908 -1.0 -3.9 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_1886 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_5403 -1.0 -6.3 ABC transporter for D-Alanine, permease component 2 (from data) compare
Pf6N2E2_4351 -1.0 -6.7 Predicted signal transduction protein compare
Pf6N2E2_2488 -1.0 -2.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1034 -1.0 -1.1 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2549 -1.0 -1.8 hypothetical protein compare
Pf6N2E2_5328 -1.0 -3.7 FIG00958649: hypothetical protein compare
Pf6N2E2_5404 -1.0 -5.9 ABC transporter for D-Alanine, permease component 1 (from data) compare
Pf6N2E2_2474 -1.0 -5.1 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_5573 -1.0 -3.7 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_4205 -0.9 -2.6 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2536 -0.9 -1.9 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf6N2E2_1113 -0.9 -2.4 Transcriptional regulator, TetR family compare
Pf6N2E2_2309 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_3039 -0.9 -4.1 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5402 -0.9 -4.8 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) compare
Pf6N2E2_2072 -0.9 -2.1 hypothetical protein compare
Pf6N2E2_2340 -0.9 -3.3 Transcriptional regulator, GntR family compare
Pf6N2E2_1806 -0.9 -1.7 hypothetical protein compare
Pf6N2E2_4764 -0.9 -3.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3933 -0.9 -3.8 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_3655 -0.9 -6.5 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_4594 -0.9 -2.8 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) compare
Pf6N2E2_1476 -0.9 -3.0 (AF179595) Vco33 compare
Pf6N2E2_1834 -0.9 -1.1 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_4636 -0.9 -4.5 periplasmic binding protein, putative compare
Pf6N2E2_2588 -0.9 -2.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3041 -0.9 -3.6 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
Pf6N2E2_3672 -0.9 -5.7 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf6N2E2_1682 -0.8 -2.7 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf6N2E2_1095 -0.8 -1.6 Opine oxidase subunit C compare
Pf6N2E2_2640 -0.8 -1.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_370 -0.8 -3.5 Predicted enzyme of the cupin superfamily compare
Pf6N2E2_3261 -0.8 -2.9 hypothetical protein compare
Pf6N2E2_5520 -0.8 -3.2 Sensory box histidine kinase compare
Pf6N2E2_1279 -0.8 -2.3 Putative PpiC-type peptidyl-prolyl cis-trans isomerase precursor associated with VreARI signaling system compare
Pf6N2E2_3480 -0.8 -1.6 Transcriptional regulator, ArsR family compare
Pf6N2E2_1652 -0.8 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_5794 -0.8 -1.9 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2674 -0.8 -1.0 FIG00953856: hypothetical protein compare
Pf6N2E2_5555 -0.8 -1.1 Cold shock protein CspA compare
Pf6N2E2_1401 -0.8 -2.0 FIG00955631: hypothetical protein compare
Pf6N2E2_4372 -0.8 -2.3 FIG00460773: hypothetical protein compare
Pf6N2E2_2267 -0.8 -2.9 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf6N2E2_1782 -0.8 -1.7 STAS domain protein compare
Pf6N2E2_5569 -0.8 -5.5 Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4) compare
Pf6N2E2_6140 -0.8 -0.7 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_624 -0.8 -3.4 hypothetical protein PA3071 compare
Pf6N2E2_660 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_1626 -0.8 -3.2 Putative ATP-binding component of a transport system compare
Pf6N2E2_3285 -0.8 -2.4 Rod shape-determining protein MreD compare
Pf6N2E2_5746 -0.8 -1.6 Cobalamin synthase compare
Pf6N2E2_4963 -0.8 -1.1 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_4987 -0.8 -1.1 MaoC-like domain protein compare
Pf6N2E2_942 -0.8 -1.8 Mll6465 protein compare
Pf6N2E2_3958 -0.8 -3.4 Putative stomatin/prohibitin-family membrane protease subunit aq_911 compare
Pf6N2E2_5300 -0.8 -5.2 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf6N2E2_2420 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_2852 -0.7 -4.6 GGDEF domain/EAL domain protein compare
Pf6N2E2_3658 -0.7 -4.2 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4399 -0.7 -4.0 GGDEF domain/EAL domain protein compare
Pf6N2E2_737 -0.7 -1.4 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2756 -0.7 -3.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2526 -0.7 -3.4 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_833 -0.7 -1.7 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf6N2E2_4761 -0.7 -4.6 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3282 -0.7 -1.4 FIG005080: Possible exported protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Asparagine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Asparagine across organisms