Experiment set8IT036 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Leucine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4826 -5.9 -5.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3782 -5.1 -3.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2193 -5.0 -6.8 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) conserved
Pf6N2E2_3248 -4.9 -4.7 Probable transmembrane protein compare
Pf6N2E2_1401 -4.7 -8.4 FIG00955631: hypothetical protein compare
Pf6N2E2_4362 -4.6 -3.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_5014 -4.4 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3841 -4.3 -4.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2588 -4.3 -5.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_2258 -4.2 -11.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3932 -4.2 -7.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2194 -4.1 -11.1 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) conserved
Pf6N2E2_2189 -4.0 -5.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_480 -4.0 -13.0 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4) (from data) conserved
Pf6N2E2_479 -3.9 -3.8 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_2217 -3.8 -3.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_37 -3.8 -3.7 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_4047 -3.8 -7.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4825 -3.8 -7.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_71 -3.8 -5.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_481 -3.8 -7.9 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) conserved
Pf6N2E2_3783 -3.8 -5.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4372 -3.7 -5.1 FIG00460773: hypothetical protein compare
Pf6N2E2_3253 -3.6 -5.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3941 -3.6 -3.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2191 -3.6 -14.7 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) conserved
Pf6N2E2_3062 -3.5 -4.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4759 -3.5 -13.4 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5156 -3.5 -2.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2192 -3.5 -10.2 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) conserved
Pf6N2E2_5176 -3.5 -9.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_477 -3.4 -5.3 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_4763 -3.4 -8.8 Biotin synthesis protein BioC compare
Pf6N2E2_3252 -3.3 -8.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3869 -3.3 -10.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_5316 -3.3 -2.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5006 -3.3 -6.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_279 -3.3 -8.6 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_1147 -3.3 -4.2 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_4761 -3.3 -9.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2753 -3.2 -3.1 HtrA protease/chaperone protein compare
Pf6N2E2_3839 -3.2 -5.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3942 -3.1 -8.7 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_1400 -3.1 -9.8 Sensory box histidine kinase/response regulator compare
Pf6N2E2_4764 -3.1 -5.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5175 -3.1 -10.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3021 -3.0 -1.5 hypothetical protein compare
Pf6N2E2_4752 -3.0 -12.1 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_3630 -3.0 -5.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -3.0 -5.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_302 -3.0 -6.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4564 -3.0 -8.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3240 -3.0 -1.8 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_1932 -2.9 -6.7 Transcriptional regulator, IclR family compare
Pf6N2E2_5160 -2.9 -1.8 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4418 -2.8 -1.0 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_5579 -2.7 -7.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4579 -2.7 -2.4 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2218 -2.7 -5.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2073 -2.7 -8.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2852 -2.6 -8.0 GGDEF domain/EAL domain protein compare
Pf6N2E2_1402 -2.6 -6.6 hypothetical protein compare
Pf6N2E2_3576 -2.6 -7.0 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) conserved
Pf6N2E2_3885 -2.5 -2.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2574 -2.5 -2.2 Flagellar synthesis regulator FleN compare
Pf6N2E2_5177 -2.5 -7.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_1381 -2.5 -6.8 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_3610 -2.4 -3.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2925 -2.4 -2.9 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 1 LivG (from data) compare
Pf6N2E2_3842 -2.4 -3.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5242 -2.4 -2.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5536 -2.4 -1.6 Holliday junction DNA helicase RuvA compare
Pf6N2E2_4416 -2.4 -3.2 Tyrosine recombinase XerC compare
Pf6N2E2_3349 -2.4 -3.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2121 -2.2 -2.2 hypothetical protein compare
Pf6N2E2_4611 -2.2 -4.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4057 -2.2 -1.1 lipoprotein, putative compare
Pf6N2E2_3786 -2.2 -2.8 Twin-arginine translocation protein TatC compare
Pf6N2E2_5972 -2.1 -4.1 hypothetical protein compare
Pf6N2E2_50 -2.1 -5.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2756 -2.1 -6.0 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_4631 -2.0 -6.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3460 -2.0 -1.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_1182 -2.0 -3.2 Transcriptional regulator, LysR family compare
Pf6N2E2_5728 -2.0 -3.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4009 -2.0 -6.8 GGDEF domain protein compare
Pf6N2E2_2510 -2.0 -4.3 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2350 -2.0 -2.1 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_5339 -2.0 -5.8 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4206 -2.0 -1.5 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2754 -1.9 -2.7 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_3118 -1.9 -3.7 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf6N2E2_2277 -1.9 -1.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2188 -1.9 -1.8 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_2752 -1.9 -6.5 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_178 -1.9 -1.4 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_2003 -1.9 -2.0 hypothetical protein compare
Pf6N2E2_3270 -1.9 -3.8 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2420 -1.8 -2.6 hypothetical protein compare
Pf6N2E2_4541 -1.8 -1.3 hypothetical protein compare
Pf6N2E2_3940 -1.8 -5.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1673 -1.8 -2.9 Transcriptional regulator, TetR family compare
Pf6N2E2_2496 -1.8 -1.6 FIG00956575: hypothetical protein compare
Pf6N2E2_4453 -1.8 -10.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3661 -1.8 -5.0 hypothetical protein compare
Pf6N2E2_2509 -1.8 -1.8 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3984 -1.7 -7.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3027 -1.7 -1.2 Baseplate assembly protein V compare
Pf6N2E2_478 -1.7 -2.4 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) conserved
Pf6N2E2_5157 -1.7 -7.6 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5337 -1.7 -3.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_5766 -1.7 -1.5 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_3597 -1.6 -3.4 hypothetical protein compare
Pf6N2E2_75 -1.6 -2.8 Colicin V production protein compare
Pf6N2E2_3578 -1.6 -8.4 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) conserved
Pf6N2E2_482 -1.6 -2.7 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_4305 -1.6 -1.0 FIG00959590: hypothetical protein compare
Pf6N2E2_3577 -1.6 -3.9 ABC transporter for L-leucine/L-isoleucine/D-alanine, ATPase component 1 LivG (from data) conserved
Pf6N2E2_1490 -1.6 -3.3 hypothetical protein compare
Pf6N2E2_5255 -1.6 -6.0 Outer membrane stress sensor protease DegS compare
Pf6N2E2_3677 -1.5 -8.9 Sensory box/GGDEF family protein compare
Pf6N2E2_3580 -1.5 -6.8 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) conserved
Pf6N2E2_84 -1.5 -1.5 hypothetical protein compare
Pf6N2E2_1056 -1.5 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_5274 -1.5 -5.0 FolM Alternative dihydrofolate reductase 1 conserved
Pf6N2E2_5338 -1.5 -4.8 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4162 -1.5 -2.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5277 -1.5 -3.8 FIG00953110: hypothetical protein compare
Pf6N2E2_89 -1.5 -2.0 hypothetical protein compare
Pf6N2E2_3480 -1.5 -1.6 Transcriptional regulator, ArsR family compare
Pf6N2E2_2923 -1.5 -6.5 ABC transporter for L-leucine/L-phenylalanine/D-alanine, permease component 1 LivH (from data) conserved
Pf6N2E2_3282 -1.5 -2.1 FIG005080: Possible exported protein compare
Pf6N2E2_2418 -1.5 -1.9 DNA-binding response regulator, LuxR family compare
Pf6N2E2_1966 -1.4 -1.9 SAM-dependent methyltransferases compare
Pf6N2E2_16 -1.4 -1.5 hypothetical protein compare
Pf6N2E2_6062 -1.4 -4.3 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_2696 -1.4 -6.9 Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) conserved
Pf6N2E2_3060 -1.4 -1.5 Outer membrane protein H precursor compare
Pf6N2E2_331 -1.4 -2.1 Putative translation initiation inhibitor, yjgF family compare
Pf6N2E2_3579 -1.4 -6.8 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) conserved
Pf6N2E2_99 -1.4 -4.2 hypothetical protein compare
Pf6N2E2_5746 -1.4 -2.3 Cobalamin synthase compare
Pf6N2E2_4459 -1.4 -0.9 Transcriptional regulator, GntR family compare
Pf6N2E2_3271 -1.4 -1.7 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3004 -1.4 -2.6 Prophage baseplate assembly protein V compare
Pf6N2E2_2886 -1.3 -7.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4159 -1.3 -2.4 Cytochrome c4 compare
Pf6N2E2_3716 -1.3 -3.3 FIG143263: Glycosyl transferase compare
Pf6N2E2_2926 -1.3 -3.8 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 2 LivF (from data) conserved
Pf6N2E2_2487 -1.3 -0.9 FIG00956090: hypothetical protein compare
Pf6N2E2_2586 -1.3 -1.0 Hpt domain protein compare
Pf6N2E2_5780 -1.3 -5.3 Periplasmic protease compare
Pf6N2E2_2682 -1.3 -1.8 Transcriptional regulator, LysR family compare
Pf6N2E2_1676 -1.3 -2.0 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_4508 -1.3 -2.0 Transcriptional regulator, TetR family compare
Pf6N2E2_4077 -1.3 -1.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2921 -1.3 -6.0 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK (from data) conserved
Pf6N2E2_4205 -1.3 -3.3 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5749 -1.3 -2.6 hypothetical protein compare
Pf6N2E2_5153 -1.3 -3.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2992 -1.3 -2.8 Regulatory protein RecX compare
Pf6N2E2_70 -1.2 -2.1 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_161 -1.2 -1.8 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) compare
Pf6N2E2_2518 -1.2 -1.6 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_902 -1.2 -2.4 hypothetical protein compare
Pf6N2E2_180 -1.2 -1.8 Transcriptional regulator, MerR family compare
Pf6N2E2_5430 -1.2 -4.9 Transglycosylase, Slt family compare
Pf6N2E2_3499 -1.2 -1.6 Permeases of the major facilitator superfamily compare
Pf6N2E2_2924 -1.2 -6.1 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, permease component 2 LivM (from data) conserved
Pf6N2E2_2111 -1.2 -2.3 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare
Pf6N2E2_4797 -1.2 -1.0 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3569 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_3305 -1.2 -1.7 hypothetical protein compare
Pf6N2E2_4187 -1.2 -2.6 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2152 -1.2 -1.1 hypothetical protein compare
Pf6N2E2_1034 -1.2 -1.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3762 -1.2 -3.1 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5666 -1.1 -4.8 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_136 -1.1 -2.8 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf6N2E2_1435 -1.1 -2.5 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_634 -1.1 -5.6 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form conserved
Pf6N2E2_3834 -1.1 -2.8 Lipoprotein NlpD compare
Pf6N2E2_3198 -1.1 -1.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2313 -1.1 -2.6 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_4680 -1.1 -2.6 HTH-type transcriptional regulator BetI compare
Pf6N2E2_3108 -1.1 -1.8 FIG00953405: hypothetical protein compare
Pf6N2E2_4762 -1.1 -1.3 Biotin synthesis protein BioH compare
Pf6N2E2_2530 -1.1 -5.4 Sensory box/GGDEF family protein compare
Pf6N2E2_4153 -1.1 -1.0 Sensory box histidine kinase compare
Pf6N2E2_1654 -1.1 -2.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_956 -1.1 -3.4 FIG01210404: hypothetical protein compare
Pf6N2E2_423 -1.1 -1.0 Putative phosphatase YfbT compare
Pf6N2E2_1735 -1.1 -1.9 PhnB protein compare
Pf6N2E2_1312 -1.1 -2.9 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare
Pf6N2E2_2010 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_4597 -1.1 -4.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5013 -1.1 -1.1 Putative membrane protein compare
Pf6N2E2_4585 -1.0 -5.3 Cell division protein FtsX compare
Pf6N2E2_4636 -1.0 -3.2 periplasmic binding protein, putative compare
Pf6N2E2_1987 -1.0 -1.1 hypothetical protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Leucine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Leucine across organisms