Experiment set8IT034 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 5mM L-Glutamate and 5mM L-Proline

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -5.3 -1.9 ferrous iron transport protein A compare
MMP_RS03450 -4.2 -2.8 glycine synthesis protein GlyXS (from data) compare
MMP_RS06355 -4.1 -4.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06680 -3.8 -21.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -3.8 -15.0 GTP 3' 8-cyclase MoaA compare
MMP_RS03435 -3.8 -2.8 ketol-acid reductoisomerase compare
MMP_RS01175 -3.7 -7.0 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05515 -3.6 -11.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05500 -3.6 -13.0 2-isopropylmalate synthase compare
MMP_RS06685 -3.5 -19.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08165 -3.5 -3.8 phosphoglycerate dehydrogenase compare
MMP_RS06345 -3.4 -14.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06350 -3.3 -6.1 HesA/MoeB/ThiF family protein compare
MMP_RS07635 -3.2 -10.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06715 -3.2 -17.5 cache domain-containing protein compare
MMP_RS07345 -3.2 -11.3 glycine synthesis protein GlyXL (from data) compare
MMP_RS09020 -3.1 -2.4 hypothetical protein compare
MMP_RS06700 -3.1 -16.6 hypothetical protein compare
MMP_RS07365 -3.1 -18.7 2-phosphoglycerate kinase compare
MMP_RS01500 -3.1 -3.9 CBS domain-containing protein compare
MMP_RS05875 -3.0 -7.4 hydroxyethylthiazole kinase compare
MMP_RS02280 -3.0 -1.4 DUF211 domain-containing protein compare
MMP_RS06720 -3.0 -9.3 response regulator transcription factor compare
MMP_RS03035 -2.9 -5.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04900 -2.9 -21.1 hypothetical protein compare
MMP_RS07730 -2.9 -2.4 pyruvate synthase subunit beta compare
MMP_RS04605 -2.8 -7.0 cobalt ECF transporter T component CbiQ compare
MMP_RS06705 -2.8 -10.2 formate/nitrite transporter family protein compare
MMP_RS05555 -2.8 -1.9 DUF4040 domain-containing protein compare
MMP_RS01385 -2.7 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07630 -2.7 -1.9 ATP-binding cassette domain-containing protein compare
MMP_RS07445 -2.7 -8.0 helix-turn-helix domain-containing protein compare
MMP_RS00695 -2.7 -1.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08745 -2.7 -7.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07845 -2.6 -3.1 LL-diaminopimelate aminotransferase compare
MMP_RS07525 -2.6 -11.5 4Fe-4S binding protein compare
MMP_RS01365 -2.5 -3.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05765 -2.5 -6.6 M42 family metallopeptidase compare
MMP_RS02010 -2.5 -10.7 PHP domain-containing protein compare
MMP_RS04615 -2.5 -3.7 PDGLE domain-containing protein compare
MMP_RS06175 -2.5 -9.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS04620 -2.4 -13.5 cobalt transporter CbiM compare
MMP_RS05425 -2.4 -5.8 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS03640 -2.3 -3.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07185 -2.3 -14.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01265 -2.3 -3.5 hypothetical protein compare
MMP_RS05085 -2.3 -12.9 AAA family ATPase compare
MMP_RS01545 -2.2 -1.6 CBS domain-containing protein compare
MMP_RS00300 -2.2 -1.1 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05095 -2.2 -7.5 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06105 -2.2 -7.1 hydrogenase maturation peptidase HycI compare
MMP_RS05080 -2.2 -12.1 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS06285 -2.2 -3.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01985 -2.2 -8.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07555 -2.2 -1.1 monovalent cation/H+ antiporter subunit E compare
MMP_RS05075 -2.1 -14.1 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08330 -2.1 -7.4 NADH-quinone oxidoreductase subunit H compare
MMP_RS03025 -2.1 -6.7 molybdenum cofactor guanylyltransferase compare
MMP_RS05100 -2.1 -15.9 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS08210 -2.1 -3.2 phosphatidylglycerophosphatase A compare
MMP_RS01610 -2.1 -4.4 hypothetical protein compare
MMP_RS05090 -2.1 -9.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS00040 -2.1 -5.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04870 -2.1 -7.2 TIGR02253 family HAD-type hydrolase compare
MMP_RS06975 -2.0 -2.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS09055 -2.0 -1.5 CAP domain-containing protein compare
MMP_RS05055 -2.0 -13.4 DUF166 domain-containing protein compare
MMP_RS01380 -2.0 -4.6 PHP domain-containing protein compare
MMP_RS05060 -2.0 -8.6 AAA family ATPase compare
MMP_RS06925 -2.0 -3.5 ribonuclease VapC4 compare
MMP_RS01220 -2.0 -7.4 hypothetical protein compare
MMP_RS06295 -2.0 -8.6 methanogenesis marker 14 protein compare
MMP_RS08720 -1.9 -1.8 4Fe-4S binding protein compare
MMP_RS06625 -1.9 -2.5 DNA primase compare
MMP_RS06840 -1.9 -1.3 DNA-directed RNA polymerase subunit N compare
MMP_RS07735 -1.9 -1.0 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05070 -1.9 -8.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS06730 -1.9 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS07575 -1.8 -4.9 RNA ligase partner protein compare
MMP_RS02800 -1.8 -4.1 nucleotidyltransferase domain-containing protein compare
MMP_RS01020 -1.8 -1.4 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS08820 -1.7 -6.4 hypothetical protein compare
MMP_RS00295 -1.7 -2.6 gamma carbonic anhydrase family protein compare
MMP_RS07545 -1.7 -1.7 HTH domain-containing protein compare
MMP_RS01800 -1.7 -3.9 TIGR00303 family protein compare
MMP_RS01085 -1.7 -2.3 hypothetical protein compare
MMP_RS08460 -1.7 -2.8 proteasome-activating nucleotidase compare
MMP_RS05065 -1.7 -4.8 CooT family nickel-binding protein compare
MMP_RS03960 -1.7 -1.4 hypothetical protein compare
MMP_RS07710 -1.7 -6.9 cell division protein FtsZ compare
MMP_RS05540 -1.6 -2.5 hypothetical protein compare
MMP_RS01195 -1.6 -1.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01445 -1.6 -7.7 hypothetical protein compare
MMP_RS00290 -1.6 -6.0 hypothetical protein compare
MMP_RS06120 -1.6 -2.3 UPF0147 family protein compare
MMP_RS05550 -1.6 -0.7 cation:proton antiporter compare
MMP_RS00620 -1.5 -5.2 4Fe-4S binding protein compare
MMP_RS00685 -1.5 -4.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08715 -1.5 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03340 -1.5 -0.9 ABC transporter ATP-binding protein compare
MMP_RS05265 -1.5 -2.4 2-isopropylmalate synthase compare
MMP_RS06400 -1.5 -1.8 4Fe-4S binding protein compare
MMP_RS03145 -1.4 -4.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08300 -1.4 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS05930 -1.4 -2.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS02355 -1.4 -2.4 30S ribosomal protein S27ae compare
MMP_RS04780 -1.4 -2.9 ribonuclease P compare
MMP_RS08645 -1.4 -7.1 UPF0179 family protein compare
MMP_RS07960 -1.4 -5.5 sugar phosphate isomerase/epimerase compare
MMP_RS07380 -1.4 -1.5 transcription elongation factor Spt5 compare
MMP_RS01755 -1.4 -1.3 DUF2097 domain-containing protein compare
MMP_RS01440 -1.4 -3.5 NAAT family transporter compare
MMP_RS07605 -1.3 -3.4 diadenylate cyclase compare
MMP_RS03600 -1.3 -2.0 triose-phosphate isomerase compare
MMP_RS00305 -1.3 -2.1 phosphoribosyl-ATP diphosphatase compare
MMP_RS05850 -1.3 -3.8 Ldh family oxidoreductase compare
MMP_RS02170 -1.3 -4.4 CBS domain-containing protein compare
MMP_RS04125 -1.3 -4.4 TetR/AcrR family transcriptional regulator compare
MMP_RS05845 -1.3 -2.0 tRNA-intron lyase compare
MMP_RS07720 -1.3 -7.4 4Fe-4S binding protein compare
MMP_RS06200 -1.3 -5.4 M24 family metallopeptidase compare
MMP_RS07200 -1.3 -4.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02240 -1.2 -2.6 methanogenesis marker 7 protein compare
MMP_RS04875 -1.2 -4.8 energy-converting hydrogenase B subunit P compare
MMP_RS00130 -1.2 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS07005 -1.2 -0.6 4Fe-4S binding protein compare
MMP_RS01005 -1.2 -1.4 riboflavin synthase compare
MMP_RS06020 -1.2 -3.9 archaeoflavoprotein AfpA compare
MMP_RS06340 -1.2 -5.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08940 -1.2 -1.0 MetS family NSS transporter small subunit compare
MMP_RS02195 -1.1 -3.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06865 -1.1 -1.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS01240 -1.1 -1.2 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS03475 -1.1 -0.7 hypothetical protein compare
MMP_RS07535 -1.1 -5.5 4Fe-4S binding protein compare
MMP_RS01325 -1.1 -1.8 dihydroneopterin aldolase family protein compare
MMP_RS02235 -1.1 -3.8 CBS domain-containing protein compare
MMP_RS04585 -1.1 -6.3 AIR synthase related protein compare
MMP_RS03140 -1.1 -7.1 hypothetical protein compare
MMP_RS08320 -1.1 -4.2 molybdopterin molybdotransferase MoeA compare
MMP_RS05245 -1.1 -6.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07705 -1.1 -4.3 transcriptional regulator compare
MMP_RS01720 -1.1 -1.7 replication factor C large subunit compare
MMP_RS05440 -1.1 -5.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS06895 -1.1 -1.1 selenocysteine-specific translation elongation factor compare
MMP_RS08790 -1.1 -1.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS08350 -1.1 -0.9 hypothetical protein compare
MMP_RS07600 -1.0 -2.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08725 -1.0 -1.2 Ni/Fe hydrogenase subunit alpha compare
MMP_RS00555 -1.0 -2.8 MFS transporter compare
MMP_RS08415 -1.0 -2.4 radical SAM protein compare
MMP_RS02165 -1.0 -4.0 tRNA-dihydrouridine synthase compare
MMP_RS02340 -1.0 -1.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01700 -1.0 -0.6 dihydroxy-acid dehydratase compare
MMP_RS01830 -1.0 -1.5 tRNA-Val compare
MMP_RS02885 -1.0 -6.7 molybdopterin biosynthesis protein compare
MMP_RS05505 -1.0 -5.6 class IV adenylate cyclase compare
MMP_RS02345 -1.0 -2.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03445 -1.0 -0.9 methanogenesis marker 17 protein compare
MMP_RS00535 -1.0 -1.7 TIGR00375 family protein compare
MMP_RS00115 -0.9 -5.4 radical SAM protein compare
MMP_RS03305 -0.9 -3.7 winged helix-turn-helix domain-containing protein compare
MMP_RS04890 -0.9 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02190 -0.9 -2.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS02045 -0.9 -1.4 tRNA-Met compare
MMP_RS03555 -0.9 -4.5 transcriptional regulator compare
MMP_RS06885 -0.9 -2.2 50S ribosome-binding GTPase compare
MMP_RS00110 -0.8 -2.0 hypothetical protein compare
MMP_RS02175 -0.8 -0.7 DUF1611 domain-containing protein compare
MMP_RS05985 -0.8 -1.2 hypothetical protein compare
MMP_RS05285 -0.8 -3.7 MMPL family transporter compare
MMP_RS04775 -0.8 -2.3 adenosylhomocysteinase compare
MMP_RS04710 -0.8 -1.0 hypothetical protein compare
MMP_RS02930 -0.8 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS06270 -0.8 -2.8 TIGR00300 family protein compare
MMP_RS06870 -0.8 -3.5 DedA family protein compare
MMP_RS05430 -0.8 -3.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS05280 -0.8 -4.7 COG1361 S-layer family protein compare
MMP_RS01075 -0.8 -1.5 hypothetical protein compare
MMP_RS07685 -0.8 -3.3 TIGR01212 family radical SAM protein compare
MMP_RS08445 -0.8 -2.4 DUF2099 family protein compare
MMP_RS00060 -0.8 -1.2 3-dehydroquinate synthase II compare
MMP_RS03485 -0.8 -2.6 TIGR00267 family protein compare
MMP_RS08635 -0.8 -1.0 UbiA family prenyltransferase compare
MMP_RS08435 -0.8 -1.2 Era-like GTP-binding protein compare
MMP_RS02900 -0.8 -0.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01745 -0.8 -2.1 AMP phosphorylase compare
MMP_RS00965 -0.7 -1.1 hypothetical protein compare
MMP_RS01570 -0.7 -1.1 hypothetical protein compare
MMP_RS04255 -0.7 -2.4 coenzyme F420 hydrogenase subunit beta compare
MMP_RS03110 -0.7 -3.2 glycosyltransferase family 2 protein compare
MMP_RS07415 -0.7 -2.5 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS05925 -0.7 -2.2 small nuclear ribonucleoprotein compare
MMP_RS03580 -0.7 -1.8 signal recognition particle-docking protein FtsY compare
MMP_RS06710 -0.7 -3.3 selenium-binding protein compare
MMP_RS08615 -0.7 -1.0 flagellar protein G compare
MMP_RS00895 -0.7 -2.0 hypothetical protein compare
MMP_RS01250 -0.7 -2.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00705 -0.7 -1.6 hypothetical protein compare
MMP_RS02875 -0.7 -2.8 chorismate pyruvate-lyase family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Glutamic acid monopotassium salt monohydrate across organisms