Experiment set8IT033 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Trisodium citrate dihydrate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.2 -4.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_2286 -5.9 -4.0 FIG00953287: hypothetical protein compare
Pf6N2E2_77 -5.7 -3.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4048 -5.6 -3.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4825 -5.5 -6.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_71 -5.4 -6.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3751 -5.2 -12.2 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3932 -5.2 -6.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4077 -5.1 -3.5 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3630 -5.1 -6.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3839 -4.9 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5175 -4.8 -12.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4047 -4.7 -5.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_64 -4.7 -4.5 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5176 -4.7 -9.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -4.6 -10.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3752 -4.6 -21.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4826 -4.5 -8.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3253 -4.5 -6.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_5014 -4.5 -2.0 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3842 -4.3 -5.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3783 -3.9 -6.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5177 -3.9 -11.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3252 -3.9 -9.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3948 -3.8 -10.8 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3782 -3.8 -5.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3610 -3.8 -5.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_66 -3.7 -10.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3940 -3.7 -11.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4360 -3.6 -12.6 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_4564 -3.6 -7.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3847 -3.4 -4.6 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_2073 -3.4 -8.3 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_302 -3.3 -6.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5616 -3.2 -7.5 outer membrane component of uptake system, probably for ferrous iron (from data) conserved
Pf6N2E2_3841 -3.2 -5.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5156 -3.2 -3.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4071 -3.1 -5.1 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5111 -3.1 -3.0 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_4638 -3.1 -3.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2074 -3.0 -1.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5618 -3.0 -10.6 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites conserved
Pf6N2E2_4447 -3.0 -14.7 Cytochrome c family protein compare
Pf6N2E2_5006 -3.0 -9.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5579 -3.0 -9.2 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3349 -2.9 -4.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3947 -2.9 -3.0 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_3661 -2.9 -6.6 hypothetical protein compare
Pf6N2E2_3255 -2.8 -5.0 YrbA protein compare
Pf6N2E2_5617 -2.8 -8.7 Iron-regulated protein A precursor compare
Pf6N2E2_4092 -2.7 -4.1 FIG00954395: hypothetical protein compare
Pf6N2E2_3908 -2.7 -6.3 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_2853 -2.6 -9.7 Iron-regulated protein A precursor conserved
Pf6N2E2_4138 -2.6 -14.1 Uncharacterized transporter, similarity to citrate transporter conserved
Pf6N2E2_942 -2.5 -3.7 Mll6465 protein compare
Pf6N2E2_3160 -2.5 -7.9 Multicopper oxidase conserved
Pf6N2E2_5667 -2.5 -7.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2465 -2.5 -7.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3251 -2.5 -10.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2830 -2.5 -4.7 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) compare
Pf6N2E2_3282 -2.5 -2.3 FIG005080: Possible exported protein compare
Pf6N2E2_4372 -2.4 -6.2 FIG00460773: hypothetical protein compare
Pf6N2E2_5331 -2.4 -8.1 ATPase, AFG1 family compare
Pf6N2E2_3984 -2.3 -10.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3170 -2.3 -7.0 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3659 -2.3 -5.4 Protein fixF compare
Pf6N2E2_5666 -2.3 -10.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3607 -2.3 -8.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_5305 -2.2 -14.7 Fe(3+) dicitrate transport protein FecA (from data) conserved
Pf6N2E2_4057 -2.2 -1.4 lipoprotein, putative compare
Pf6N2E2_5307 -2.2 -6.4 FIG006045: Sigma factor, ECF subfamily conserved
Pf6N2E2_2217 -2.2 -5.3 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_623 -2.2 -2.2 FIG00954674: hypothetical protein compare
Pf6N2E2_3480 -2.1 -2.4 Transcriptional regulator, ArsR family compare
Pf6N2E2_63 -2.1 -3.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2914 -2.1 -8.6 4-hydroxybenzoate 3-monooxygenase (EC 1.14.13.2) (from data) compare
Pf6N2E2_5527 -2.1 -2.4 Cold shock protein CspC compare
Pf6N2E2_2834 -2.1 -5.1 Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) compare
Pf6N2E2_2839 -2.0 -9.7 Pca regulon regulatory protein PcaR compare
Pf6N2E2_2753 -2.0 -3.0 HtrA protease/chaperone protein compare
Pf6N2E2_3248 -2.0 -5.2 Probable transmembrane protein compare
Pf6N2E2_2513 -2.0 -4.9 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2913 -2.0 -7.9 Transcriptional regulator PobR, AraC family compare
Pf6N2E2_178 -2.0 -1.9 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3460 -1.9 -1.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_451 -1.9 -2.6 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_5728 -1.9 -4.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4612 -1.9 -4.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_4759 -1.9 -11.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4827 -1.8 -4.9 Lipoate-protein ligase A compare
Pf6N2E2_5520 -1.8 -7.0 Sensory box histidine kinase compare
Pf6N2E2_4369 -1.8 -2.1 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_2367 -1.8 -1.7 hypothetical protein compare
Pf6N2E2_2218 -1.8 -4.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2831 -1.8 -3.9 3-carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2) compare
Pf6N2E2_2277 -1.7 -2.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2674 -1.7 -1.5 FIG00953856: hypothetical protein compare
Pf6N2E2_2510 -1.7 -3.9 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3762 -1.7 -5.7 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_2827 -1.7 -1.7 hypothetical protein compare
Pf6N2E2_4009 -1.7 -7.0 GGDEF domain protein compare
Pf6N2E2_2473 -1.7 -1.6 Major outer membrane lipoprotein I compare
Pf6N2E2_2833 -1.7 -5.2 Protocatechuate 3,4-dioxygenase alpha chain (EC 1.13.11.3) compare
Pf6N2E2_2829 -1.7 -3.3 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf6N2E2_3899 -1.6 -7.5 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_89 -1.6 -2.9 hypothetical protein compare
Pf6N2E2_5031 -1.6 -4.8 hypothetical protein compare
Pf6N2E2_5679 -1.6 -2.8 hypothetical protein compare
Pf6N2E2_5669 -1.6 -5.6 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_2837 -1.6 -7.6 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6); Glutaconate CoA-transferase subunit A (EC 2.8.3.12) compare
Pf6N2E2_3667 -1.6 -1.4 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_2251 -1.5 -2.6 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf6N2E2_1083 -1.5 -2.3 hypothetical protein compare
Pf6N2E2_4162 -1.5 -3.1 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_50 -1.5 -5.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3763 -1.5 -2.1 hypothetical protein compare
Pf6N2E2_4414 -1.5 -1.4 FIG00953808: hypothetical protein compare
Pf6N2E2_3514 -1.5 -3.7 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_2838 -1.5 -6.5 4-hydroxybenzoate transporter compare
Pf6N2E2_70 -1.5 -4.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3876 -1.4 -4.5 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_6058 -1.4 -5.3 FIG139976: hypothetical protein compare
Pf6N2E2_2282 -1.4 -3.4 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3300 -1.4 -3.7 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2281 -1.4 -2.7 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_446 -1.3 -6.1 Glutathione reductase (EC 1.8.1.7) compare
Pf6N2E2_2274 -1.3 -5.1 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_4987 -1.3 -1.3 MaoC-like domain protein compare
Pf6N2E2_2835 -1.3 -1.9 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf6N2E2_3786 -1.3 -3.3 Twin-arginine translocation protein TatC compare
Pf6N2E2_5086 -1.3 -1.3 hypothetical protein compare
Pf6N2E2_6057 -1.2 -2.2 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_5258 -1.2 -5.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5727 -1.2 -4.1 FIG00955360: hypothetical protein compare
Pf6N2E2_2836 -1.2 -2.5 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6); Glutaconate CoA-transferase subunit B (EC 2.8.3.12) compare
Pf6N2E2_6047 -1.2 -1.8 hypothetical protein compare
Pf6N2E2_5990 -1.2 -1.6 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_4963 -1.2 -2.0 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_4422 -1.2 -1.6 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_3933 -1.2 -4.3 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_5487 -1.2 -2.8 Nitrogen regulation protein NR(I) compare
Pf6N2E2_1718 -1.2 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_5178 -1.2 -2.0 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_5219 -1.2 -4.8 FIG140336: TPR domain protein compare
Pf6N2E2_4160 -1.2 -1.4 Cytochrome c5 compare
Pf6N2E2_3335 -1.1 -8.0 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf6N2E2_4120 -1.1 -7.6 Trk system potassium uptake protein TrkA compare
Pf6N2E2_5243 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_2413 -1.1 -1.8 FIG074102: hypothetical protein compare
Pf6N2E2_4797 -1.1 -1.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_1081 -1.1 -1.7 probable membrane protein YPO3302 compare
Pf6N2E2_339 -1.1 -2.1 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_4136 -1.1 -5.1 Aromatic ring-cleaving dioxygenase compare
Pf6N2E2_3835 -1.0 -2.9 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5188 -1.0 -3.4 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2065 -1.0 -2.3 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2487 -1.0 -0.9 FIG00956090: hypothetical protein compare
Pf6N2E2_4351 -1.0 -4.9 Predicted signal transduction protein compare
Pf6N2E2_5257 -1.0 -6.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5306 -1.0 -5.5 Iron siderophore sensor protein compare
Pf6N2E2_1156 -1.0 -2.5 hypothetical protein compare
Pf6N2E2_3305 -1.0 -2.7 hypothetical protein compare
Pf6N2E2_5155 -1.0 -1.7 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5500 -1.0 -1.9 MoxR-like ATPases compare
Pf6N2E2_3872 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_5772 -1.0 -2.6 DUF1232 domain-containing protein compare
Pf6N2E2_1056 -1.0 -0.9 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2420 -1.0 -2.4 hypothetical protein compare
Pf6N2E2_4025 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_5668 -1.0 -2.8 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) compare
Pf6N2E2_2022 -0.9 -3.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3323 -0.9 -2.7 hypothetical protein compare
Pf6N2E2_65 -0.9 -3.5 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf6N2E2_5406 -0.9 -1.9 FIG00958224: hypothetical protein compare
Pf6N2E2_3346 -0.9 -4.2 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2438 -0.9 -0.9 hypothetical protein compare
Pf6N2E2_3183 -0.9 -2.0 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2089 -0.9 -3.2 Transcriptional regulator, AraC family compare
Pf6N2E2_754 -0.9 -1.2 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_5499 -0.9 -1.0 hypothetical protein compare
Pf6N2E2_4423 -0.9 -1.9 FIG00953342: hypothetical protein compare
Pf6N2E2_2832 -0.9 -5.3 dicarboxylic acid transporter PcaT compare
Pf6N2E2_3277 -0.9 -1.8 FagA protein compare
Pf6N2E2_5072 -0.9 -4.7 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) compare
Pf6N2E2_122 -0.9 -1.2 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_2973 -0.9 -2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2156 -0.9 -1.8 Putative polyketide synthase (Fragment) compare
Pf6N2E2_331 -0.9 -2.5 Putative translation initiation inhibitor, yjgF family compare
Pf6N2E2_5720 -0.9 -5.5 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4416 -0.9 -1.8 Tyrosine recombinase XerC compare
Pf6N2E2_4614 -0.8 -2.2 twitching motility protein PilH compare
Pf6N2E2_1376 -0.8 -2.6 probable transmembrane protein compare
Pf6N2E2_3204 -0.8 -2.2 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_3557 -0.8 -1.7 Chaperone-modulator protein CbpM compare
Pf6N2E2_4206 -0.8 -1.0 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5950 -0.8 -2.6 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2693 -0.8 -1.3 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_3039 -0.8 -3.5 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_4139 -0.8 -4.7 Integral membrane protein TerC compare
Pf6N2E2_1312 -0.8 -2.1 4-hydroxyphenylacetate symporter, major facilitator superfamily (MFS) compare


Specific Phenotypes

For 25 genes in this experiment

For carbon source Trisodium citrate dihydrate in Pseudomonas fluorescens FW300-N2E2

For carbon source Trisodium citrate dihydrate across organisms