Experiment set8IT033 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 5mM L-Glutamate and 5mM L-Tyrosine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS03615 +2.0 17.6 4Fe-4S binding protein compare
MMP_RS03620 +1.5 9.0 hypothetical protein compare
MMP_RS01370 +1.2 6.5 acetate--CoA ligase family protein compare
MMP_RS01540 +1.2 4.9 DUF504 domain-containing protein compare
MMP_RS04720 +1.1 2.8 DedA family protein compare
MMP_RS01775 +1.1 2.9 TIGR00297 family protein compare
MMP_RS04550 +1.0 6.6 S-layer protein compare
MMP_RS01895 +1.0 7.9 flippase compare
MMP_RS01650 +1.0 1.3 sulfurtransferase TusA family protein compare
MMP_RS01955 +0.9 3.3 hypothetical protein compare
MMP_RS07875 +0.9 4.3 hypothetical protein compare
MMP_RS06395 +0.9 3.1 ThiF family adenylyltransferase compare
MMP_RS06575 +0.9 3.4 fluoride efflux transporter CrcB compare
MMP_RS07115 +0.8 4.9 MBL fold metallo-hydrolase compare
MMP_RS06570 +0.8 4.3 DUF190 domain-containing protein compare
MMP_RS05640 +0.8 4.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS05355 +0.8 1.0 hypothetical protein compare
MMP_RS07125 +0.8 3.7 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01100 +0.8 1.6 ABC transporter ATP-binding protein compare
MMP_RS01905 +0.8 6.4 glycosyltransferase compare
MMP_RS03300 +0.8 0.9 TOBE domain-containing protein compare
MMP_RS08155 +0.8 3.7 hypothetical protein compare
MMP_RS07120 +0.7 4.4 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06310 +0.7 2.9 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01875 +0.7 4.9 N-acetyltransferase compare
MMP_RS01880 +0.7 4.7 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01900 +0.7 5.6 hypothetical protein compare
MMP_RS06670 +0.7 3.3 glucose-6-phosphate isomerase compare
MMP_RS08930 +0.7 1.6 hypothetical protein compare
MMP_RS03215 +0.7 4.7 MBL fold metallo-hydrolase compare
MMP_RS01910 +0.7 5.1 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS07390 +0.7 2.3 cell division protein FtsZ compare
MMP_RS08500 +0.6 2.5 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS00945 +0.6 1.1 PadR family transcriptional regulator compare
MMP_RS01940 +0.6 2.2 MoxR family ATPase compare
MMP_RS01925 +0.6 3.9 DUF1616 domain-containing protein compare
MMP_RS02310 +0.6 1.4 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS04740 +0.6 3.1 DUF473 domain-containing protein compare
MMP_RS04520 +0.6 1.6 nucleoside deaminase compare
MMP_RS01885 +0.6 3.8 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01970 +0.6 4.7 TIGR04279 domain-containing protein compare
MMP_RS08705 +0.6 3.9 sulfopyruvate decarboxylase subunit beta compare
MMP_RS07130 +0.6 3.2 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS08090 +0.6 3.0 hypothetical protein compare
MMP_RS05525 +0.6 2.7 calcium/sodium antiporter compare
MMP_RS06525 +0.6 0.9 YciI family protein compare
MMP_RS07695 +0.6 3.1 DUF3236 domain-containing protein compare
MMP_RS06440 +0.5 3.4 CBS domain-containing protein compare
MMP_RS08280 +0.5 2.1 proteasome assembly chaperone family protein compare
MMP_RS06550 +0.5 3.3 AMP-binding protein compare
MMP_RS06905 +0.5 1.8 hypothetical protein compare
MMP_RS01930 +0.5 4.3 hypothetical protein compare
MMP_RS00725 +0.5 1.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04850 +0.5 4.4 UPF0254 family protein compare
MMP_RS00185 +0.5 3.5 potassium channel protein compare
MMP_RS06965 +0.5 2.2 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS06745 +0.5 2.4 DUF2119 domain-containing protein compare
MMP_RS08890 +0.5 4.1 glycosyltransferase family 4 protein compare
MMP_RS08315 +0.5 2.1 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS02110 +0.5 1.3 hypothetical protein compare
MMP_RS00315 +0.5 2.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01975 +0.5 3.9 hypothetical protein compare
MMP_RS02495 +0.5 1.7 hypothetical protein compare
MMP_RS09025 +0.5 0.8 hypothetical protein compare
MMP_RS01525 +0.5 1.1 nucleoside-diphosphate kinase compare
MMP_RS05980 +0.5 3.0 ferritin compare
MMP_RS05720 +0.5 2.5 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS07820 +0.5 1.8 UPF0104 family protein compare
MMP_RS00395 +0.5 1.0 MGMT family protein compare
MMP_RS00940 +0.5 3.1 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS00660 +0.4 2.6 alkaline phosphatase family protein compare
MMP_RS07915 +0.4 1.9 DUF4870 domain-containing protein compare
MMP_RS08265 +0.4 2.4 rubrerythrin compare
MMP_RS00880 +0.4 1.9 ribosome assembly RNA-binding protein YhbY compare
MMP_RS01915 +0.4 3.4 DUF354 domain-containing protein compare
MMP_RS01950 +0.4 2.9 hypothetical protein compare
MMP_RS01920 +0.4 3.4 glycosyltransferase family 2 protein compare
MMP_RS00375 +0.4 2.5 ammonium transporter compare
MMP_RS08160 +0.4 2.9 EamA family transporter compare
MMP_RS05360 +0.4 2.2 hypothetical protein compare
MMP_RS08775 +0.4 1.8 methanogenesis marker 9 domain-containing protein compare
MMP_RS03280 +0.4 2.8 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS06155 +0.4 1.4 DUF4186 domain-containing protein compare
MMP_RS06480 +0.4 2.4 ABC transporter substrate-binding protein compare
MMP_RS08555 +0.4 1.1 hypothetical protein compare
MMP_RS08275 +0.4 2.1 hypothetical protein compare
MMP_RS07700 +0.4 2.1 DUF1188 domain-containing protein compare
MMP_RS02490 +0.4 2.0 hypothetical protein compare
MMP_RS03830 +0.4 2.9 exodeoxyribonuclease VII large subunit compare
MMP_RS02475 +0.4 0.7 hypothetical protein compare
MMP_RS08470 +0.4 2.7 ATP-binding cassette domain-containing protein compare
MMP_RS08640 +0.4 2.3 TIM barrel protein compare
MMP_RS06940 +0.4 1.9 polyprenyl diphosphate synthase compare
MMP_RS06585 +0.4 0.9 DMT family protein compare
MMP_RS00735 +0.4 1.2 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01055 +0.4 1.7 hypothetical protein compare
MMP_RS01435 +0.4 2.0 DMT family transporter compare
MMP_RS08400 +0.4 1.0 MJ0307 family thioredoxin compare
MMP_RS03895 +0.4 1.4 hypothetical protein compare
MMP_RS08175 +0.4 2.6 7-cyano-7-deazaguanine synthase compare
MMP_RS06535 +0.4 1.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS02815 +0.4 0.9 hypothetical protein compare
MMP_RS07385 +0.4 0.8 protein translocase SEC61 complex subunit gamma compare
MMP_RS00825 +0.4 1.9 fumarylacetoacetate hydrolase family protein compare
MMP_RS05535 +0.4 1.3 hypothetical protein compare
MMP_RS06545 +0.4 2.3 ferredoxin family protein compare
MMP_RS03245 +0.4 2.0 DNA repair and recombination protein RadB compare
MMP_RS05990 +0.3 1.5 DsrE family protein compare
MMP_RS05700 +0.3 2.4 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS00100 +0.3 2.2 tRNA pseudouridine(13) synthase TruD compare
MMP_RS02265 +0.3 1.1 nitroreductase family protein compare
MMP_RS00385 +0.3 1.6 P-II family nitrogen regulator compare
MMP_RS07895 +0.3 1.5 cytochrome c compare
MMP_RS01030 +0.3 1.6 MTAP family purine nucleoside phosphorylase compare
MMP_RS03965 +0.3 1.0 hypothetical protein compare
MMP_RS06555 +0.3 1.3 cupin domain-containing protein compare
MMP_RS02780 +0.3 2.2 hypothetical protein compare
MMP_RS00635 +0.3 1.4 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS08455 +0.3 1.3 multiprotein bridging factor aMBF1 compare
MMP_RS08475 +0.3 1.8 ABC transporter permease compare
MMP_RS01860 +0.3 2.3 hypothetical protein compare
MMP_RS00955 +0.3 2.1 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS01470 +0.3 1.4 ATP-binding cassette domain-containing protein compare
MMP_RS01620 +0.3 1.1 hypothetical protein compare
MMP_RS00560 +0.3 2.0 cation:proton antiporter compare
MMP_RS05975 +0.3 0.5 hypothetical protein compare
MMP_RS05275 +0.3 2.2 AI-2E family transporter compare
MMP_RS00140 +0.3 1.5 DUF192 domain-containing protein compare
MMP_RS03770 +0.3 1.8 hydroxylamine reductase compare
MMP_RS06600 +0.3 0.6 class III signal peptide-containing protein compare
MMP_RS06530 +0.3 1.2 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS08650 +0.3 0.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00960 +0.3 1.6 iron export ABC transporter permease subunit FetB compare
MMP_RS07620 +0.3 1.0 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS04265 +0.3 0.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02725 +0.3 1.2 molybdate ABC transporter permease subunit compare
MMP_RS06365 +0.3 0.8 hypothetical protein compare
MMP_RS00085 +0.3 2.2 DNA cytosine methyltransferase compare
MMP_RS01685 +0.3 1.1 indolepyruvate oxidoreductase subunit beta compare
MMP_RS01945 +0.3 1.9 DUF4350 domain-containing protein compare
MMP_RS04475 +0.3 1.5 nitrogen fixation compare
MMP_RS02915 +0.3 1.7 amino acid ABC transporter permease compare
MMP_RS04270 +0.3 1.6 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS04425 +0.3 2.3 APC family permease compare
MMP_RS09035 +0.3 0.7 hypothetical protein compare
MMP_RS00795 +0.3 1.6 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08700 +0.3 2.0 hypothetical protein compare
MMP_RS02645 +0.3 1.7 ArsR family transcriptional regulator compare
MMP_RS01980 +0.3 2.1 trimeric intracellular cation channel family protein compare
MMP_RS04165 +0.3 1.2 TetR/AcrR family transcriptional regulator compare
MMP_RS08480 +0.3 2.1 molybdate ABC transporter substrate-binding protein compare
MMP_RS03840 +0.3 1.2 hypothetical protein compare
MMP_RS02910 +0.3 1.3 ABC transporter substrate-binding protein compare
MMP_RS01065 +0.3 2.1 alpha/beta hydrolase compare
MMP_RS07890 +0.3 0.8 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS00380 +0.3 1.2 P-II family nitrogen regulator compare
MMP_RS06500 +0.3 1.6 ATP-binding protein compare
MMP_RS00450 +0.3 0.5 4Fe-4S binding protein compare
MMP_RS08945 +0.3 1.8 hypothetical protein compare
MMP_RS08485 +0.3 1.6 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS06320 +0.3 1.5 hypothetical protein compare
MMP_RS03150 +0.3 2.0 phosphoglycerate mutase compare
MMP_RS08620 +0.3 1.2 flagellar accessory protein FlaH compare
MMP_RS02895 +0.3 1.7 DHH family phosphoesterase compare
MMP_RS05170 +0.3 1.7 lysine exporter LysO family protein compare
MMP_RS03870 +0.3 1.3 purine NTPase compare
MMP_RS04690 +0.3 0.7 class III signal peptide-containing protein compare
MMP_RS01430 +0.3 1.1 mechanosensitive ion channel family protein compare
MMP_RS08235 +0.2 0.8 hypothetical protein compare
MMP_RS08405 +0.2 1.6 MFS transporter compare
MMP_RS02965 +0.2 1.5 carboxymuconolactone decarboxylase family protein compare
MMP_RS02325 +0.2 1.6 epoxyqueuosine reductase compare
MMP_RS07330 +0.2 2.1 membrane protein compare
MMP_RS05580 +0.2 2.0 glycosyltransferase compare
MMP_RS00155 +0.2 1.4 heavy metal-binding domain-containing protein compare
MMP_RS03750 +0.2 1.2 ACT domain-containing protein compare
MMP_RS07970 +0.2 0.8 hypothetical protein compare
MMP_RS06290 +0.2 0.8 DNA repair and recombination protein RadA compare
MMP_RS01640 +0.2 1.6 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS00800 +0.2 1.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00630 +0.2 1.0 ECF transporter S component compare
MMP_RS08835 +0.2 1.1 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS04965 +0.2 1.2 thioredoxin family protein compare
MMP_RS00650 +0.2 1.3 ABC transporter ATP-binding protein compare
MMP_RS01145 +0.2 1.2 ABC transporter ATP-binding protein compare
MMP_RS09050 +0.2 1.1 CAP domain-containing protein compare
MMP_RS03395 +0.2 0.8 hypothetical protein compare
MMP_RS03775 +0.2 0.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS04715 +0.2 1.1 CBS domain-containing protein compare
MMP_RS07135 +0.2 1.1 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02675 +0.2 0.7 hypothetical protein compare
MMP_RS01935 +0.2 1.6 DUF58 domain-containing protein compare
MMP_RS08430 +0.2 1.2 HAD family hydrolase compare
MMP_RS06275 +0.2 1.5 ATP-dependent DNA helicase compare
MMP_RS06605 +0.2 1.2 DUF5814 domain-containing protein compare
MMP_RS06045 +0.2 1.6 DNA polymerase compare
MMP_RS06520 +0.2 1.0 DUF1786 domain-containing protein compare
MMP_RS05955 +0.2 0.6 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS08880 +0.2 1.7 hypothetical protein compare
MMP_RS00055 +0.2 1.3 DUF2254 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Glutamic acid monopotassium salt monohydrate across organisms