Experiment set8IT031 for Methanococcus maripaludis S2

Compare to:

Mc formate, casamino free, with 5mM L-Glutamate and 5mM L-Tyrosine

200 most important genes:

  gene name fitness t score description  
MMP_RS08165 -4.3 -4.5 phosphoglycerate dehydrogenase compare
MMP_RS06355 -4.3 -4.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06350 -4.2 -10.1 HesA/MoeB/ThiF family protein compare
MMP_RS07345 -4.2 -12.8 glycine synthesis protein GlyXL (from data) compare
MMP_RS05515 -4.0 -11.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03015 -4.0 -15.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07635 -4.0 -11.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08720 -3.8 -3.0 4Fe-4S binding protein compare
MMP_RS06680 -3.8 -21.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05500 -3.8 -13.8 2-isopropylmalate synthase compare
MMP_RS01175 -3.5 -10.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06685 -3.4 -17.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06700 -3.4 -16.4 hypothetical protein compare
MMP_RS06345 -3.3 -15.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06715 -3.1 -17.2 cache domain-containing protein compare
MMP_RS07555 -3.1 -1.4 monovalent cation/H+ antiporter subunit E compare
MMP_RS01500 -3.0 -5.1 CBS domain-containing protein compare
MMP_RS06720 -3.0 -9.9 response regulator transcription factor compare
MMP_RS07845 -2.9 -3.1 LL-diaminopimelate aminotransferase compare
MMP_RS01455 -2.9 -12.7 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS02010 -2.9 -10.9 PHP domain-containing protein compare
MMP_RS03640 -2.9 -4.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04605 -2.7 -8.4 cobalt ECF transporter T component CbiQ compare
MMP_RS03450 -2.7 -4.1 glycine synthesis protein GlyXS (from data) compare
MMP_RS03315 -2.7 -1.9 ferrous iron transport protein A compare
MMP_RS07445 -2.7 -8.9 helix-turn-helix domain-containing protein compare
MMP_RS06705 -2.7 -10.8 formate/nitrite transporter family protein compare
MMP_RS07630 -2.7 -2.9 ATP-binding cassette domain-containing protein compare
MMP_RS00300 -2.6 -1.3 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08460 -2.6 -4.4 proteasome-activating nucleotidase compare
MMP_RS04900 -2.6 -20.0 hypothetical protein compare
MMP_RS07185 -2.5 -17.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06375 -2.5 -9.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS05425 -2.5 -6.2 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06105 -2.5 -9.2 hydrogenase maturation peptidase HycI compare
MMP_RS07365 -2.5 -15.4 2-phosphoglycerate kinase compare
MMP_RS07525 -2.5 -9.5 4Fe-4S binding protein compare
MMP_RS05555 -2.5 -2.2 DUF4040 domain-containing protein compare
MMP_RS04215 -2.5 -10.8 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS04620 -2.4 -12.9 cobalt transporter CbiM compare
MMP_RS03035 -2.4 -4.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04615 -2.4 -4.3 PDGLE domain-containing protein compare
MMP_RS06270 -2.4 -5.5 TIGR00300 family protein compare
MMP_RS08820 -2.3 -6.5 hypothetical protein compare
MMP_RS02235 -2.3 -8.9 CBS domain-containing protein compare
MMP_RS03435 -2.3 -2.6 ketol-acid reductoisomerase compare
MMP_RS00040 -2.3 -5.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06295 -2.3 -9.4 methanogenesis marker 14 protein compare
MMP_RS01755 -2.2 -1.9 DUF2097 domain-containing protein compare
MMP_RS06175 -2.2 -8.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS08715 -2.1 -2.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02355 -2.1 -4.9 30S ribosomal protein S27ae compare
MMP_RS03445 -2.1 -1.6 methanogenesis marker 17 protein compare
MMP_RS05930 -2.1 -4.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS01020 -2.1 -1.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06730 -2.0 -2.5 phosphopantothenate/pantothenate synthetase compare
MMP_RS08745 -2.0 -9.5 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01005 -2.0 -2.1 riboflavin synthase compare
MMP_RS08330 -2.0 -7.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS00695 -2.0 -1.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01325 -1.9 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS00620 -1.9 -7.2 4Fe-4S binding protein compare
MMP_RS07005 -1.9 -0.9 4Fe-4S binding protein compare
MMP_RS04710 -1.9 -2.1 hypothetical protein compare
MMP_RS08300 -1.8 -1.8 metal-sulfur cluster assembly factor compare
MMP_RS02240 -1.8 -4.4 methanogenesis marker 7 protein compare
MMP_RS01545 -1.8 -1.7 CBS domain-containing protein compare
MMP_RS01265 -1.8 -2.4 hypothetical protein compare
MMP_RS05875 -1.8 -6.9 hydroxyethylthiazole kinase compare
MMP_RS07575 -1.8 -4.4 RNA ligase partner protein compare
MMP_RS01795 -1.8 -2.5 methanogenesis marker 6 protein compare
MMP_RS03025 -1.8 -6.0 molybdenum cofactor guanylyltransferase compare
MMP_RS01365 -1.7 -3.7 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05550 -1.7 -0.8 cation:proton antiporter compare
MMP_RS08790 -1.7 -3.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS09020 -1.6 -2.4 hypothetical protein compare
MMP_RS06285 -1.6 -3.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07380 -1.6 -3.2 transcription elongation factor Spt5 compare
MMP_RS05095 -1.6 -4.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS00685 -1.6 -4.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01220 -1.6 -7.7 hypothetical protein compare
MMP_RS07730 -1.6 -2.3 pyruvate synthase subunit beta compare
MMP_RS05540 -1.6 -3.1 hypothetical protein compare
MMP_RS05060 -1.6 -7.0 AAA family ATPase compare
MMP_RS06925 -1.6 -2.9 ribonuclease VapC4 compare
MMP_RS01195 -1.6 -1.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05765 -1.6 -6.7 M42 family metallopeptidase compare
MMP_RS01085 -1.5 -2.5 hypothetical protein compare
MMP_RS00115 -1.5 -9.4 radical SAM protein compare
MMP_RS04870 -1.5 -5.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS01830 -1.5 -2.4 tRNA-Val compare
MMP_RS07545 -1.5 -1.8 HTH domain-containing protein compare
MMP_RS06340 -1.5 -7.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06975 -1.5 -2.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS00305 -1.4 -1.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS02195 -1.4 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07735 -1.4 -0.9 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS09055 -1.4 -1.5 CAP domain-containing protein compare
MMP_RS05100 -1.4 -9.4 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS08210 -1.4 -2.2 phosphatidylglycerophosphatase A compare
MMP_RS05265 -1.4 -2.7 2-isopropylmalate synthase compare
MMP_RS04780 -1.4 -3.2 ribonuclease P compare
MMP_RS05085 -1.4 -7.9 AAA family ATPase compare
MMP_RS02340 -1.4 -2.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS04125 -1.3 -3.1 TetR/AcrR family transcriptional regulator compare
MMP_RS01985 -1.3 -5.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05075 -1.3 -8.5 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS01385 -1.3 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07600 -1.3 -2.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05430 -1.3 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS00295 -1.3 -2.3 gamma carbonic anhydrase family protein compare
MMP_RS08940 -1.3 -1.3 MetS family NSS transporter small subunit compare
MMP_RS03485 -1.3 -5.4 TIGR00267 family protein compare
MMP_RS02345 -1.3 -3.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS02800 -1.3 -3.9 nucleotidyltransferase domain-containing protein compare
MMP_RS05080 -1.3 -6.8 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS02885 -1.2 -8.9 molybdopterin biosynthesis protein compare
MMP_RS05090 -1.2 -5.7 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06020 -1.2 -3.5 archaeoflavoprotein AfpA compare
MMP_RS04875 -1.2 -5.3 energy-converting hydrogenase B subunit P compare
MMP_RS04585 -1.2 -7.5 AIR synthase related protein compare
MMP_RS06625 -1.2 -1.8 DNA primase compare
MMP_RS01700 -1.2 -0.9 dihydroxy-acid dehydratase compare
MMP_RS05070 -1.2 -4.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS03960 -1.2 -1.3 hypothetical protein compare
MMP_RS01800 -1.1 -2.6 TIGR00303 family protein compare
MMP_RS06840 -1.1 -1.1 DNA-directed RNA polymerase subunit N compare
MMP_RS06865 -1.1 -1.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02280 -1.1 -1.0 DUF211 domain-containing protein compare
MMP_RS05055 -1.1 -7.8 DUF166 domain-containing protein compare
MMP_RS08320 -1.1 -3.7 molybdopterin molybdotransferase MoeA compare
MMP_RS04790 -1.1 -6.1 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00555 -1.1 -4.0 MFS transporter compare
MMP_RS00130 -1.1 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS08615 -1.1 -1.2 flagellar protein G compare
MMP_RS08350 -1.1 -1.0 hypothetical protein compare
MMP_RS05245 -1.1 -5.0 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS04890 -1.0 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01720 -1.0 -1.1 replication factor C large subunit compare
MMP_RS01380 -1.0 -4.1 PHP domain-containing protein compare
MMP_RS07625 -1.0 -1.7 cobalt ECF transporter T component CbiQ compare
MMP_RS01610 -1.0 -3.3 hypothetical protein compare
MMP_RS06200 -1.0 -5.0 M24 family metallopeptidase compare
MMP_RS05850 -1.0 -2.1 Ldh family oxidoreductase compare
MMP_RS07535 -1.0 -5.9 4Fe-4S binding protein compare
MMP_RS07605 -1.0 -2.1 diadenylate cyclase compare
MMP_RS07200 -0.9 -4.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00750 -0.9 -1.7 fumarate hydratase compare
MMP_RS00455 -0.9 -4.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS01240 -0.9 -1.0 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS02930 -0.9 -2.1 class I SAM-dependent methyltransferase compare
MMP_RS06930 -0.9 -5.6 MBL fold metallo-hydrolase compare
MMP_RS01440 -0.9 -2.8 NAAT family transporter compare
MMP_RS01250 -0.9 -3.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00720 -0.9 -3.6 metal-dependent hydrolase compare
MMP_RS00535 -0.9 -1.5 TIGR00375 family protein compare
MMP_RS08725 -0.9 -1.0 Ni/Fe hydrogenase subunit alpha compare
MMP_RS02135 -0.9 -2.9 DUF5612 domain-containing protein compare
MMP_RS00895 -0.9 -2.7 hypothetical protein compare
MMP_RS03580 -0.9 -2.9 signal recognition particle-docking protein FtsY compare
MMP_RS01445 -0.9 -4.4 hypothetical protein compare
MMP_RS03145 -0.9 -4.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS03600 -0.9 -1.5 triose-phosphate isomerase compare
MMP_RS08635 -0.8 -1.4 UbiA family prenyltransferase compare
MMP_RS03080 -0.8 -2.6 universal stress protein compare
MMP_RS08645 -0.8 -3.4 UPF0179 family protein compare
MMP_RS04685 -0.8 -1.9 DUF126 domain-containing protein compare
MMP_RS00060 -0.8 -1.5 3-dehydroquinate synthase II compare
MMP_RS02900 -0.8 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07720 -0.8 -4.4 4Fe-4S binding protein compare
MMP_RS05920 -0.8 -0.5 50S ribosomal protein L37e compare
MMP_RS07860 -0.8 -0.8 hypothetical protein compare
MMP_RS07705 -0.8 -3.1 transcriptional regulator compare
MMP_RS06400 -0.8 -1.1 4Fe-4S binding protein compare
MMP_RS00320 -0.7 -1.4 class I SAM-dependent methyltransferase compare
MMP_RS06230 -0.7 -1.8 helix-turn-helix domain-containing protein compare
MMP_RS08750 -0.7 -1.6 hypothetical protein compare
MMP_RS02175 -0.7 -0.7 DUF1611 domain-containing protein compare
MMP_RS01600 -0.7 -1.2 50S ribosomal protein L15e compare
MMP_RS06120 -0.7 -1.5 UPF0147 family protein compare
MMP_RS04410 -0.7 -1.4 hypothetical protein compare
MMP_RS01575 -0.7 -4.0 aldolase compare
MMP_RS03555 -0.7 -3.6 transcriptional regulator compare
MMP_RS07415 -0.7 -3.2 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02045 -0.7 -1.3 tRNA-Met compare
MMP_RS00985 -0.7 -2.9 CDC48 family AAA ATPase compare
MMP_RS07960 -0.7 -3.3 sugar phosphate isomerase/epimerase compare
MMP_RS05250 -0.7 -1.5 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05950 -0.7 -2.8 nickel-dependent hydrogenase large subunit compare
MMP_RS03205 -0.7 -1.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01075 -0.7 -1.1 hypothetical protein compare
MMP_RS05105 -0.7 -3.8 thymidylate synthase compare
MMP_RS08230 -0.7 -2.0 50S ribosomal protein L11 methyltransferase compare
MMP_RS00810 -0.6 -3.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01745 -0.6 -1.8 AMP phosphorylase compare
MMP_RS02170 -0.6 -2.1 CBS domain-containing protein compare
MMP_RS06215 -0.6 -1.5 30S ribosomal protein S6e compare
MMP_RS03250 -0.6 -1.7 MJ1244 family protein compare
MMP_RS07765 -0.6 -2.4 sodium:alanine symporter family protein compare
MMP_RS06885 -0.6 -1.4 50S ribosome-binding GTPase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 L-Glutamic acid monopotassium salt monohydrate across organisms