Experiment set8IT024 for Pseudomonas fluorescens FW300-N2E2

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Cytosine nitrogen source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3060 -6.8 -4.7 Outer membrane protein H precursor compare
Pf6N2E2_4826 -6.5 -4.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4353 -6.5 -4.5 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_4825 -6.2 -4.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3783 -6.1 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3842 -6.1 -4.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_64 -6.0 -4.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_77 -5.9 -4.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_71 -5.8 -5.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3630 -5.8 -5.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3751 -5.8 -11.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3253 -5.8 -4.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4597 -5.7 -7.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4596 -5.7 -6.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5006 -5.7 -5.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5175 -5.7 -9.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_2588 -5.6 -3.9 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3264 -5.6 -3.8 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_5177 -5.6 -9.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_5176 -5.5 -6.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_2258 -5.4 -9.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4047 -5.3 -3.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3554 -5.3 -9.5 GCN5-related N-acetyltransferase compare
Pf6N2E2_3248 -5.2 -6.2 Probable transmembrane protein compare
Pf6N2E2_1187 -5.2 -9.3 Probable nikkomycin biosynthesis protein, carboxylase compare
Pf6N2E2_3839 -5.0 -3.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3610 -4.9 -6.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2073 -4.9 -4.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3841 -4.9 -3.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_1186 -4.9 -6.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_4279 -4.9 -13.3 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3940 -4.9 -13.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3752 -4.8 -21.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3251 -4.7 -10.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_658 -4.7 -13.5 sensor histidine kinase compare
Pf6N2E2_3932 -4.7 -6.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4564 -4.7 -10.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3782 -4.7 -4.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4278 -4.6 -11.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_5014 -4.6 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4987 -4.6 -2.1 MaoC-like domain protein compare
Pf6N2E2_3826 -4.4 -6.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_2885 -4.4 -5.2 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_4048 -4.3 -7.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4372 -4.3 -4.2 FIG00460773: hypothetical protein compare
Pf6N2E2_4071 -4.3 -5.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3072 -4.2 -12.4 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_3252 -4.2 -9.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_66 -4.2 -9.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2897 -4.1 -12.2 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_4611 -3.9 -3.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_146 -3.9 -3.5 Transcriptional regulator, MarR family compare
Pf6N2E2_50 -3.9 -8.2 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5150 -3.8 -8.0 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_5780 -3.8 -11.9 Periplasmic protease compare
Pf6N2E2_5156 -3.8 -2.6 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5337 -3.6 -6.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_1189 -3.6 -8.2 Thioredoxin reductase (EC 1.8.1.9) compare
Pf6N2E2_4277 -3.5 -10.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2261 -3.5 -5.7 VacJ-like lipoprotein precursor compare
Pf6N2E2_4759 -3.4 -15.9 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3260 -3.4 -5.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3258 -3.4 -3.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5160 -3.3 -3.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3938 -3.3 -13.4 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3257 -3.3 -3.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_1190 -3.3 -7.0 Glutamine-dependent 2-keto-4-methylthiobutyrate transaminase compare
Pf6N2E2_3825 -3.2 -4.7 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_3463 -3.2 -12.7 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) conserved
Pf6N2E2_1672 -3.2 -10.2 hypothetical protein compare
Pf6N2E2_2074 -3.2 -2.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5527 -3.2 -3.0 Cold shock protein CspC compare
Pf6N2E2_2218 -3.2 -5.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_1188 -3.2 -6.5 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_5339 -3.1 -7.6 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3464 -3.1 -12.4 LysR family transcriptional regulator PA0133 compare
Pf6N2E2_5705 -3.1 -3.5 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_1673 -3.0 -4.4 Transcriptional regulator, TetR family compare
Pf6N2E2_63 -3.0 -4.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5338 -2.9 -9.9 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4638 -2.9 -4.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2895 -2.9 -10.4 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_2474 -2.8 -10.8 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_3869 -2.8 -11.6 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3170 -2.8 -6.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2891 -2.7 -12.0 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_2117 -2.7 -14.3 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_5579 -2.7 -6.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_2892 -2.6 -12.6 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_5679 -2.6 -4.8 hypothetical protein compare
Pf6N2E2_5536 -2.6 -1.7 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3835 -2.6 -3.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_4187 -2.5 -5.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2890 -2.4 -7.7 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_2574 -2.4 -2.1 Flagellar synthesis regulator FleN compare
Pf6N2E2_1056 -2.3 -1.3 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1191 -2.3 -7.4 Thiaminase II (EC 3.5.99.2) compare
Pf6N2E2_2889 -2.3 -9.4 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_5219 -2.3 -8.4 FIG140336: TPR domain protein compare
Pf6N2E2_34 -2.3 -6.2 Cytosine deaminase (EC 3.5.4.1) conserved
Pf6N2E2_4764 -2.2 -5.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2893 -2.2 -6.3 hypothetical protein compare
Pf6N2E2_3664 -2.2 -10.2 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_4797 -2.1 -2.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_178 -2.1 -2.0 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3786 -2.1 -4.5 Twin-arginine translocation protein TatC compare
Pf6N2E2_302 -2.1 -4.9 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3984 -2.1 -11.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5666 -2.1 -10.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4009 -2.1 -8.4 GGDEF domain protein compare
Pf6N2E2_497 -2.0 -7.5 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism conserved
Pf6N2E2_1072 -2.0 -6.2 LmbE-like protein compare
Pf6N2E2_3198 -2.0 -2.2 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_500 -2.0 -2.9 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_70 -2.0 -4.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2274 -1.9 -5.7 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2746 -1.9 -6.4 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_498 -1.9 -6.0 Dihydropyrimidinase (EC 3.5.2.2) (from data) conserved
Pf6N2E2_2888 -1.9 -9.3 Glucose-selective porin OprB compare
Pf6N2E2_5258 -1.9 -8.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4453 -1.9 -11.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2217 -1.8 -5.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3325 -1.8 -3.1 ABC transporter, ATP-binding protein compare
Pf6N2E2_6099 -1.8 -2.1 tRNA-Glu-TTC compare
Pf6N2E2_2795 -1.8 -3.7 putative exported protein compare
Pf6N2E2_2527 -1.8 -4.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_496 -1.8 -8.4 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) conserved
Pf6N2E2_2552 -1.8 -4.5 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_3349 -1.8 -2.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4159 -1.8 -4.5 Cytochrome c4 compare
Pf6N2E2_4391 -1.7 -6.0 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_2465 -1.7 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3667 -1.7 -1.5 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3373 -1.7 -2.3 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_5111 -1.7 -2.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2896 -1.6 -2.2 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_5494 -1.6 -5.2 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_1932 -1.6 -5.9 Transcriptional regulator, IclR family compare
Pf6N2E2_2340 -1.6 -3.4 Transcriptional regulator, GntR family compare
Pf6N2E2_3607 -1.6 -6.3 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_4276 -1.5 -4.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_1987 -1.5 -2.5 hypothetical protein compare
Pf6N2E2_3666 -1.5 -3.2 InaA protein compare
Pf6N2E2_2899 -1.5 -4.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3300 -1.5 -4.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_4351 -1.5 -7.7 Predicted signal transduction protein compare
Pf6N2E2_3476 -1.4 -9.7 Nucleoside ABC transporter, periplasmic nucleoside-binding protein conserved
Pf6N2E2_2311 -1.4 -6.6 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_499 -1.4 -3.6 Possible pyrimidine permease in reductive pathway conserved
Pf6N2E2_5728 -1.4 -4.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_942 -1.4 -2.1 Mll6465 protein compare
Pf6N2E2_3661 -1.4 -4.5 hypothetical protein compare
Pf6N2E2_3469 -1.4 -8.4 Nucleoside ABC transporter, permease protein 2 conserved
Pf6N2E2_5739 -1.4 -2.0 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_3665 -1.4 -1.2 serine/threonine protein kinase compare
Pf6N2E2_5524 -1.4 -6.9 Outer membrane porin, OprD family compare
Pf6N2E2_5257 -1.4 -8.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2753 -1.4 -2.8 HtrA protease/chaperone protein compare
Pf6N2E2_754 -1.4 -2.2 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_1034 -1.4 -2.0 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2470 -1.3 -7.7 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf6N2E2_2264 -1.3 -3.3 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2473 -1.3 -1.5 Major outer membrane lipoprotein I compare
Pf6N2E2_2310 -1.3 -7.7 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3323 -1.3 -4.1 hypothetical protein compare
Pf6N2E2_4072 -1.3 -4.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2863 -1.3 -5.8 Gluconate permease compare
Pf6N2E2_3834 -1.3 -4.4 Lipoprotein NlpD compare
Pf6N2E2_2320 -1.3 -3.3 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_863 -1.3 -4.8 Transcriptional regulator, IclR family compare
Pf6N2E2_3521 -1.3 -6.5 Sensor histidine kinase/response regulator compare
Pf6N2E2_3908 -1.3 -4.9 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3468 -1.3 -7.5 Nucleoside ABC transporter, permease protein 1 conserved
Pf6N2E2_5508 -1.3 -2.1 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_2188 -1.2 -3.7 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_5554 -1.2 -4.4 FIG023103: Predicted transmembrane protein compare
Pf6N2E2_4817 -1.2 -9.5 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_4763 -1.2 -5.8 Biotin synthesis protein BioC compare
Pf6N2E2_40 -1.2 -2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2864 -1.2 -1.7 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_4416 -1.2 -2.2 Tyrosine recombinase XerC compare
Pf6N2E2_3833 -1.2 -2.5 hypothetical protein compare
Pf6N2E2_2822 -1.2 -5.2 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_5746 -1.2 -3.1 Cobalamin synthase compare
Pf6N2E2_2317 -1.2 -3.5 Putative analog of CcoH, COG3198 compare
Pf6N2E2_2313 -1.2 -2.5 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_4963 -1.2 -1.4 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_2827 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_4631 -1.2 -7.3 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2938 -1.2 -3.5 Outer membrane lipoprotein compare
Pf6N2E2_1652 -1.2 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_1606 -1.2 -5.0 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2292 -1.2 -1.3 Universal stress protein family COG0589 compare
Pf6N2E2_4761 -1.2 -5.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_1848 -1.1 -3.2 hypothetical protein compare
Pf6N2E2_1288 -1.1 -1.7 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_2518 -1.1 -2.0 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_4077 -1.1 -2.4 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_3505 -1.1 -1.7 Translation initiation factor SUI1-related protein compare
Pf6N2E2_5331 -1.1 -4.3 ATPase, AFG1 family compare


Specific Phenotypes

For 18 genes in this experiment

For nitrogen source Cytosine in Pseudomonas fluorescens FW300-N2E2

For nitrogen source Cytosine across organisms